Reduced Alzheimer's disease β-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin

Journal of Neuroscience

Volumn 30, Issue 48, 2010, Pages 16160-16169

  Meckler, Xavier ^a   Roseman, Jelita ^a   Das, Pritam ^b   Cheng, Haipeng ^a   Pei, Susan ^a   Keat, Marcia ^a   Kassarjian, Breanne ^a   Golde, Todd E ^c   Parent, Angèle T ^a   Thinakaran, Gopal ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; DENDRITE; FOREBRAIN; FRONTAL CORTEX; GENE EXPRESSION; MOUSE; NERVE FIBER; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN STABILITY; TRANSGENE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ENDOPEPTIDASES; LIPOYLATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID;

EID: 78649733057     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4436-10.2010     Document Type: Article

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