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TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver
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Human tribbles, a protein family controlling mitogen-activated protein kinase cascades
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Kiss-Toth E., Bagstaff S.M., Sung H.Y., Jozsa V., Dempsey C., Caunt J.C., Oxley K.M., Wyllie D.H., Polgar T., Harte M., O'Neill A., Qwarnstrom E.E., and Dower S.K. Human tribbles, a protein family controlling mitogen-activated protein kinase cascades. J. Biol. Chem. 279 (2004) 42703-42708
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SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia
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TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism
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Qi L., Heredia J.E., Altarejos J.Y., Screaton R., Goebel N., Niessen S., Macleod I.X., Liew C.W., Kulkarni R.N., Bain J., Newgard C., Nelson M., Evans R.M., Yates J., and Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science 312 (2006) 1763-1766
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Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity
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Matsushima R., Harada N., Webster N.J., Tsutsumi Y.M., and Nakaya Y. Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity. J. Biol. Chem. 281 (2006) 29719-29729
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Mouse NIPK interacts with ATF4 and affects its transcriptional activity
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Regulation of expression and signalling modulator function of mammalian tribbles is cell-type specific
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Sung H.Y., Francis S.E., Crossman D.C., and Kiss-Toth E. Regulation of expression and signalling modulator function of mammalian tribbles is cell-type specific. Immunol. Lett. 104 (2006) 171-177
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TRB3 is a PI 3-kinase dependent indicator for nutrient starvation
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Schwarzer R., Dames S., Tondera D., Klippel A., and Kaufmann J. TRB3 is a PI 3-kinase dependent indicator for nutrient starvation. Cell. Signal. 18 (2006) 899-909
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PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
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Koo S.H., Satoh H., Herzig S., Lee C.H., Hedrick S., Kulkarni R., Evans R.M., Olefsky J., and Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat. Med. 10 (2004) 530-534
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TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
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Ohoka N., Yoshii S., Hattori T., Onozaki K., and Hayashi H. TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J. 24 (2005) 1243-1255
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Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions
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Ord D., and Ord T. Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions. Biochem. Biophys. Res. Commun. 330 (2005) 210-218
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Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression
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Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation
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He L., Simmen F.A., Mehendale H.M., Ronis M.J., and Badger T.M. Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. J. Biol. Chem. 281 (2006) 11126-11134
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CtIP, a candidate tumor susceptibility gene is a team player with luminaries
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Intranuclear localization of the transcription coadaptor CBP/p300 and the transcription factor RBP-Jk in relation to EBNA-2 and-5 in B lymphocytes
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Bandobashi K., Maeda A., Teramoto N., Nagy N., Szekely L., Taguchi H., Miyoshi I., Klein G., and Klein E. Intranuclear localization of the transcription coadaptor CBP/p300 and the transcription factor RBP-Jk in relation to EBNA-2 and-5 in B lymphocytes. Virology 288 (2001) 275-282
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RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression
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Chatterjee T.K., and Fisher R.A. RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression. Mol.Cell. Biol. 22 (2002) 4334-4345
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Glucose, dexamethasone and the unfolded protein response regulate TRB3 mRNA expression in 3T3-L1 adipocytes and L6 myotubes
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(in press)
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Yacoub Wasef S.Z., Robinson K.A., Berkaw M.N., and Buse M.G. Glucose, dexamethasone and the unfolded protein response regulate TRB3 mRNA expression in 3T3-L1 adipocytes and L6 myotubes. Am. J. Physiol. Endocrinol. Metab. (2006) (in press)
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