Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells

Oncogene

Volumn 29, Issue 20, 2010, Pages 2973-2982

  Zanella, F ^a   Renner, O ^a   Garcia B ^a   Callejas, S ^b   Dopazo, A ^b   Peregrina, S ^a   Carnero, A ^a   Link, W ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

FOXO; Melanoma; RNAi; Screening; TRIB2

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DROSOPHILA; GENE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE SILENCING; GENETIC IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MELANOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA INTERFERENCE; SKIN CANCER; TRIB2 GENE; TRIBBLES GENE; TUMOR GROWTH; TUMOR XENOGRAFT; WOUND HEALING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; CYTOPLASM; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MELANOMA; MICE; MICE, SCID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR MARKERS, BIOLOGICAL; WOUND HEALING;

MAMMALIA;

EID: 77952672913     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.58     Document Type: Article

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