Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury

European Journal of Pharmacology

Volumn 556, Issue 1-3, 2007, Pages 69-74

  Takeuchi, Yuichi ^a   Takasu, Keiko ^a   Honda, Motoko ^a   Ono, Hideki ^a   Tanabe, Mitsuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Descending noradrenergic system; Gabapentin; Neuropathic pain; Noradrenaline turnover; Spinal cord

Indexed keywords

4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; BRAIN MONOAMINE; DOPAMINE; GABAPENTIN; NORADRENALIN; SEROTONIN;

5 HYDROXYINDOLEACETIC ACID BRAIN LEVEL; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOSE RESPONSE; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERSENSITIVITY; MOUSE; NERVE LIGATION; NEUROCHEMISTRY; NEUROPATHIC PAIN; NONHUMAN; NORADRENALIN BRAIN LEVEL; NORADRENALIN RELEASE; NORADRENERGIC SYSTEM; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL; TREATMENT RESPONSE;

AMINES; ANALGESICS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; HYDROXYINDOLEACETIC ACID; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MALE; METHOXYHYDROXYPHENYLGLYCOL; MICE; NOREPINEPHRINE; PAIN; PAIN MEASUREMENT; SCIATIC NERVE; SCIATIC NEUROPATHY; SEROTONIN; SPINAL CORD;

EID: 33846083305     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.10.059     Document Type: Article

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