A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics

Journal of Pharmacology and Experimental Therapeutics

Volumn 335, Issue 3, 2010, Pages 600-606

  McCracken, Mandy L ^a   Borghese, Cecilia M ^a   Trudell, James R ^b   Harris, R Adron ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; ALCOHOL; ALFAXALONE; ANESTHETIC AGENT; BUTANOL; CYSTEINE; FLUNITRAZEPAM; ISOFLURANE; OCTANOL; PENTOBARBITAL; THIOL GROUP;

ARTICLE; BINDING SITE; DRUG BINDING; DRUG EFFECT; ELECTROPHYSIOLOGY; FEMALE; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; XENOPUS LAEVIS;

1-BUTANOL; 1-OCTANOL; ALCOHOLS; AMINO ACID SUBSTITUTION; ANESTHETICS; ANIMALS; ASPARAGINE; BINDING SITES; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ETHANOL; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; ION CHANNEL GATING; ISOFLURANE; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, GABA-A; RNA, COMPLEMENTARY; THIOSULFONIC ACIDS; XENOPUS LAEVIS;

EID: 78649626143     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.170472     Document Type: Article

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