A β-strand in the γ2 subunit lines the benzodiazepine binding site of the GABAA receptor: Structural rearrangements detected during channel gating

Journal of Neuroscience

Volumn 21, Issue 14, 2001, Pages 4977-4986

  Teissére, Jeremy A ^a   Czajkowski, Cynthia ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Allostery; Benzodiazepine; Binding site; GABA; GABAA receptor; Ligand gated ion channel; Secondary structure; Substituted cysteine accessibility method; Xenopus oocytes

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; ION CHANNEL; MESYLIC ACID; THIOL DERIVATIVE;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; BETA CHAIN; CHANNEL GATING; CONFORMATION; COVALENT BOND; DRUG BINDING SITE; DRUG RECEPTOR BINDING; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; XENOPUS LAEVIS;

EID: 0035879190     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-14-04977.2001     Document Type: Article

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