Soluble Jagged1 attenuates lateral inhibition, allowing for the clonal expansion of neural crest stem cells

Stem Cells

Volumn 25, Issue 12, 2007, Pages 3133-3142

  Nikopoulos, George N ^a   Duarte, Maria ^b   Kubu, Chris J ^b   Bellum, Stephen ^b   Friesel, Robert ^b   Maciag, Thomas ^b   Prudovsky, Igor ^b   Verdi, Joseph M ^b  

^a UNIVERSITY OF MAINE   (United States)

^b Maine Medical Center Research Institute   (United States)

Author keywords

Adherent cells; Apoptosis; Cellular therapy; Delta1; Developmental biology; Neural crest; Notch; Self renewal

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; JAGGED1; NOTCH RECEPTOR;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL RENEWAL; CELL TRANSPLANTATION; CELL VIABILITY; CONTROLLED STUDY; GLIA CELL; HUMAN; HUMAN CELL; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST; NONHUMAN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; STEM CELL; TISSUE REPAIR;

ANIMALS; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CLONE CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NEURAL CREST; NEURAL INHIBITION; NEURONS; RATS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SOLUBILITY; STEM CELLS;

EID: 37349007419     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0327     Document Type: Article

References (41)

1. Sommer L, Rao M. Neural stem cells and regulation of cell number. Prog Neurobiol 2002;66:1-18.
2. Cavaleri F, Scholer HR. Nanog: A new recruit to the embryonic stem cell orchestra. Cell 2003;113:551-552.
3. Tsai RY, Kittappa R, McKay RD. Plasticity, niches, and the use of stem cells. Dev Cell 2002;2:707-712.
4. Chambers I. The molecular basis of pluripotency in mouse embryonic stem cells. Cloning Stem Cells 2004;6:386-391.
5. Chambers I, Smith A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 2004;23:7150-7160.
6. Park IK, Morrison SJ, Clarke MF. Bmi1, stem cells, and senescence regulation. J Clin Invest 2004;113:175-179.
7. Kubu CJ, Orimoto K, Morrison SJ et al. Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells. Dev Biol 2002;244:199-214.
8. White PM, Morrison SJ, Orimoto K et al. Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals. Neuron 2001;29:57-71.
9. Burns CE, Traver D, Mayhall E et al. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev 2005;19:2331-2342.
10. Chadwick N, Nostro MC, Baron M et al. Notch signaling induces apoptosis in primary human CD34+ hematopoietic progenitor cells. STEM CELLS 2007;25:203-210.
11. Guentchev M, McKay RD. Notch controls proliferation and differentiation of stem cells in a dose-dependent manner. Eur J Neurosci 2006;23:2289-2296.
12. Jadhav AP, Cho SH, Cepko CL. Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proc Natl Acad Sci U S A 2006;103:18998-19003.
13. Jadhav AP, Mason HA, Cepko CL. Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development 2006;133:913-923.
14. Jundt F, Anagnostopoulos I, Forster R et al. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood 2002;99:3398-3403.
15. Sarmento LM, Huang H, Limon A et al. Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation. J Exp Med 2005;202:157-168.
16. Chiba S. Notch signaling in stem cell systems. STEM CELLS 2006;24:2437-2447.
17. Yeo SY, Chitnis AB. Jagged-mediated Notch signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord. Proc Natl Acad Sci U S A 2007;104:5913-5918.
18. Morrison SJ, Perez SE, Qiao Z et al. Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 2000;101:499-510.
19. Chambers CB, Peng Y, Nguyen H et al. Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors. Development 2001;128:689-702.
20. Gaiano N, Nye JS, Fishell G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 2000;26:395-404.
21. Nye JS, Kopan R, Axel R. An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development 1994;120:2421-2430.
22. Christiansen JH, Coles EG, Wilkinson DG. Molecular control of neural crest formation, migration and differentiation. Curr Opin Cell Biol 2000;12:719-724.
23. Lundkvist J, Lendahl U. Notch and the birth of glial cells. Trends Neurosci 2001;24:492-494.
24. Vetter ML, Moore KB. Becoming glial in the neural retina. Dev Dyn 2001;221:146-153.
25. Wang S, Barres BA. Up a notch: Instructing gliogenesis. Neuron 2000;27:197-200.
26. Artavanis-Tsakonas S, Matsuno K, Fortini ME. Notch signaling. Science 1995;268:225-232.
27. Kadesch T. Notch signaling: A dance of proteins changing partners. Exp Cell Res 2000;260:1-8.
28. Weinmaster G. The ins and outs of notch signaling. Mol Cell Neurosci 1997;9:91-102.
29. Hu QD, Ang BT, Karsak M et al. F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 2003;115:163-175.
30. Small D, Kovalenko D, Kacer D et al. Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype. J Biol Chem 2001;276:32022-32030.
31. Stemple DL, Anderson DJ. Isolation of a stem cell for neurons and glia from the mammalian neural crest. Cell 1992;71:973-985.
32. Morrison SJ, White PM, Zock C et al. Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells. Cell 1999;96:737-749.
33. Verdi JM, Ip N, Yancopoulos GD et al. Expression of trk in MAH cells lacking the p75 low-affinity nerve growth factor receptor is sufficient to permit nerve growth factor-induced differentiation to postmitotic neurons. Proc Natl Acad Sci U S A 1994;91:3949-3953.
34. Amsen D, Blander JM, Lee GR et al. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 2004;117:515-526.
35. Nomaguchi K, Suzu S, Yamada M et al. Expression of Jagged1 gene in macrophages and its regulation by hematopoietic growth factors. Exp Hematol 2001;29:850-855.
36. Coffman CR, Skoglund P, Harris WA et al. Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos. Cell 1993;73:659-671.
37. Fortini ME, Rebay I, Caron LA et al. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 1993;365:555-557.
38. Struhl G, Fitzgerald K, Greenwald I. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 1993;74:331-345.
39. Bani-Yaghoub M, Kubu CJ, Cowling R et al. A switch in numb isoforms is a critical step in cortical development. Dev Dyn 2007;236:696-705; erratum in Dev Dyn 2007;236:1158.
40. Small D, Kovalenko D, Soldi R et al. Notch activation suppresses fibroblast growth factor-dependent cellular transformation. J Biol Chem 2003;278:16405-16413.
41. Hitoshi S, Alexson T, Tropepe V et al. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev 2002;16:846-858.