Acetylcholine acutely modifies nitric oxide synthase function in the human coronary circulation

Experimental Physiology

Volumn 95, Issue 12, 2010, Pages 1167-1176

  Miner, Steven E S ^a,b   Al Hesayen, Abdul ^b   Nield, Lynne E ^b,c   Gori, Tommaso ^b   Parker, John D ^b  

^a SOUTHLAKE REGIONAL HEALTH CENTRE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLESTEROL; CREATININE; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE;

ADULT; ANGIOCARDIOGRAPHY; ARTERY DIAMETER; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY SINUS; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DISEASE SEVERITY; DRUG DOSE INCREASE; ENZYME ACTIVITY; FEMALE; HUMAN; HYPERTENSION; INTRACORONARY INFUSION; MALE; OXYGEN SATURATION; SMOKING; VASOMOTOR REFLEX;

EID: 78649568171     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2010.053926     Document Type: Article

References (60)

1. Abu-Soud HM, Ichimori K, Presta A & Stuehr DJ (2000). Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase. J Biol Chem 275, 17349-173457.
2. Adak S, Wang Q & Stuehr DJ (2000). Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism. J Biol Chem 275, 33554-33561.
3. Adelman AG, Cohen EA, Kimball BP, Bonan R, Ricci DR, Webb JG, Laramee L, Barbeau G, Trabousi M & Corbett BN (1993). A comparison of directional atherectomy with balloon angioplasty for lesions of the left anterior descending coronary artery. N Engl J Med 329, 228-233.
4. Anderson RA, Jones CJ & Goodfellow J (2001). Is the fatty meal a trigger for acute coronary syndromes. Atherosclerosis 159, 9-15.
5. Anderson TJ, Worthley MI, Goodhart DM & Curtis MJ (2005). Relation of basal coronary nitric oxide activity to the burden of atherosclerosis. Am J Cardiol 95, 1170-1174.
6. 2 adrenergic receptors in human atherosclerotic coronary arteries. Circulation 111, 288-294.
7. Bellamy MF, McDowell IF, Ramsey MW, Brownlee M, Bones C, Newcombe RG & Lewis MJ (1998). Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults. Circulation 98, 1848-1852.
8. Beltran B, Orsi A, Clementi E & Moncada S (2000). Oxidative stress and S-nitrosylation of proteins in cells. Br J Pharmacol 129, 953-960.
9. 2+ during acetycholine-induced dilation of microvessels. Br J Pharmacol 128, 124-134.
10. G-Nitro l-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists. Circ Res 72, 387-395.
11. Chao CL, Kuo TL & Lee YT (2000). Effects of methionine-induced hyperhomocysteinemia on endothelium-dependent vasodilation and oxidative status in healthy adults. Circulation 101, 485-490.
12. Chiu JJ, Wung BS, Shyy JY, Hsieh HJ & Wang DL (1997). Reactive oxygen species are involved in shear stress-induced intercellular adhesion molecule-1 expression in endothelial cells. Arterioscler Thromb Vasc Biol 17, 3570-3577.
13. Closs EI, Scheld JS, Sharafi M & Forstermann U (2000). Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol Pharmacol 57, 68-74.
14. Cosentino F & Luscher TF (1998). Tetrahydrobiopterin and endothelial function. Eur Heart J 19 (Suppl G), G3-G8.
15. Ding X & Murray PA (2007). Acetylcholine activates protein kinse C-α in pulmnary venous smooth muscle. Anesthesiology 106, 507-514.
16. Duffy SJ, Castle SF, Harper RW & Meredith IT (1999). Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation. Circulation 100, 1951-1957.
17. Eu JP, Liu L, Zeng M & Stamler JS (2000). An apoptotic model for nitrosative stress. Biochemistry 39, 1040-1047.
18. Gordon JB, Ganz P, Nabel EG, Fish RD, Zebede J, Mudge GH, Alexander RW & Selwyn AP (1989). Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise. J Clin Invest 83, 1946-1952.
19. Gori T, Burstein JM, Ahmed S, Miner SE, Al-Hesayen A, Kelly S & Parker JD (2001). Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation 104, 1119-1123.
20. Griscavage JM, Hobbs AJ & Ignarro LJ (1995). Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds. Adv Pharmacol 34, 215-234.
21. Harrison D, Griendling KK, Landmesser U, Hornig B & Drexler H (2003). Role of oxidative stress in atherosclerosis. Am J Cardiol 91, 7A-11A.
22. + accumulation in acetylcholine-induced desensitization of guinea pig ileal longitudinal muscle. Jpn J Pharmacol 74, 291-295.
23. 2+-free conditions. J Auton Pharmacol 19, 275-280.
24. Horio Y, Yasue H, Rokutanda M, Nakamura N, Ogawa H, Takaoka K, Matsuyama K & Kimura T (1986). Effects of intracoronary injection of acetylcholine on coronary arterial diameter. Am J Cardiol 57, 984-989.
25. Hryhorenko LM, Woskowska Z & Fox-Threlkeld JA (1994). Nitric oxide (NO) inhibits release of acetylcholine from nerves of isolated circular muscle of the canine ileum: relationship to motility and release of nitric oxide. J Pharmacol Exp Ther 271, 918-926.
26. Hsieh HJ, Cheng CC, Wu ST, Chiu JJ, Wung BS & Wang DL (1998). Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression. J Cell Physiol 175, 156-162.
27. + conductances in human bronchial smooth muscle. Am J Physiol Lung Cell Mol Physiol 270, L772-L781.
28. Kaye DM, Ahlers BA, Autelitano DJ & Chin-Dusting JP (2000). In vivo and in vitro evidence for impaired arginine transport in human heart failure. Circulation 102, 2707-2712.
29. Kim H, Sohn UD, Mangannan V, Rich H, Jain MK, Behar J & Biancani P (1997). Leukotrines in acetylcholine-induced contraction of esophageal circular smooth muscle in experimental esophagitis. Gastroenterology 112, 1548-1558.
30. Kugiyama K, Yasue H, Okumura K, Ogawa H, Fujimoto K, Nakao K, Yoshimura M, Motoyama T, Inobe Y & Kawano H (1996). Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina. Circulation 94, 266-271.
31. Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, Tarpey M, Fukai T & Harrison DG (2001). Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation 103, 1282-1288.
32. Lefroy DC, Crake T, Uren NG, Davies GJ & Maseri A (1993). Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans. Circulation 88, 43-54.
33. 2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res 93, 573-580.
34. Milstien S & Katusic Z (1999). Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263, 681-684.
35. Miner SE, Al-Hesayen A, Kelly S, Beson T, Thiessen JJ, Young VR & Parker JD (2004). L-Arginine transport in the human coronary and peripheral circulation. Circulation 109, 1278-1283.
36. Mitsutake R, Niimura H, Miura S, Zhang B, Iwata A, Nishikawa H, Kawamura A, Kumagai K, Shirai K, Matsunaga A & Saku K (2006). Clinical significance of the coronary calcification score by multidetector row computed tomography for the evaluation of coronary stenosis in Japanese patients. Circ J 70, 1122-1127.
37. Oemar BS, Tschudi MR, Godoy N, Brovkovich V, Malinski T & Luscher TF (1998). Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis. Circulation 97, 2494-2498.
38. Prakash YS, Kannan MS & Sieck GC (1997). Regulation of intracellular calcium oscillations in porcine tracheal smooth muscle cells. Am J Physiol Cell Physiol 272, C966-C975.
39. Pritchard KA Jr, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, Wolin MS & Stemerman MB (1995). Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 77, 510-518.
40. Quyyumi AA, Dakak N, Diodati JG, Gilligan DM, Panza JA & Cannon RO III (1997a). Effect of l-arginine on human coronary endothelium-dependent and physiologic vasodilation. J Am Coll Cardiol 30, 1220-1227.
41. Quyyumi AA, Dakak N, Mulcahy D, Andrews NP, Husain S, Panza JA, Cannon RO & Cannon OR III (1997b). Nitric oxide activity in the atherosclerotic human coronary circulation. J Am Coll Cardiol 29, 308-317.
42. Rees DD, Palmer RM, Hodson HF & Moncada S (1989). A specific inhibitor of nitric oxide formation from l-arginine attenuates endothelium-dependent relaxation. Br J Pharmacol 96, 418-424.
43. Sarabi M, Fugmann A, Karlstrom B, Berne C, Lithell H & Lind L (2001). An ordinary mixed meal transiently impairs endothelium-dependent vasodilation in healthy subjects. Acta Physiol Scand 172, 107-113.
44. Schachinger V, Britten MB & Zeiher AM (2000). Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101, 1899-1906.
45. Schachinger V & Zeiher AM (1995). Quantitative assessment of coronary vasoreactivity in humans in vivo. Importance of baseline vasomotor tone in atherosclerosis. Circulation 92, 2087-2094.
46. Schwartz D, Mendonca M, Schwartz I, Xia Y, Satriano J, Wilson CB & Blantz RC (1997). Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest 100, 439-448.
47. Silvestro A, Scopacasa F, Oliva G, De Cristofaro T, Iuliano L & Brevetti G (2002). Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis 165, 277-283.
48. Stamler JS (1994). Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78, 931-936.
49. Stocker R, Huang A, Jeranian E, Hou JY, Wu TT, Thomas SR & Keaney JF (2004). Hypochlorous acid impairs endothelium-derived nitric oxide bioactivity through a superoxide-dependent mechanism. Arterioscler Thromb Vasc Biol 24, 2028-2033.
50. Tentolouris C, Tousoulis D, Crake T, Katsimaglis G, Stefanadis C, Davies G & Toutouzas P (1999). Inhibition of nitric oxide synthesis in human epicardial coronary arteries and stenoses in relation to serum lipid level. Atherosclerosis 147, 285-291.
51. Tiefenbacher CP, Chilian WM, Mitchell M & DeFily DV (1996). Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin. Circulation 94, 1423-1429.
52. Tousoulis D, Tentolouris C, Crake T, Toutouzas P & Davies G (1997). Basal and flow-mediated nitric oxide production by atheromatous coronary arteries. J Am Coll Cardiol 29, 1256-1262.
53. Traverse JH, Wang YL, Du R, Nelson D, Lindstrom P, Archer SL, Gong G & Bache RJ (2000). Coronary nitric oxide production in response to exercise and endothelium-dependent agonists. Circulation 101, 2526-2531.
54. Traylor LA & Mayeux PR (1997). Superoxide generation by renal proximal tubule nitric oxide synthase. Nitric Oxide 1, 432-438.
55. Von Mering GO, Arant CB, Wessel TR, McGorray SP, Bairey Merz CN, Sharaf BL, Smith KM, Olson MB, Johnson BD, Sopko G, Handberg E, Pepine CJ & Kerensky RA (2004). Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung and Blood Institue-sponsored women's ischemia syndrome evaluation (WISE). Circulation 109, 722-725.
56. Wang W, Wang S, Yan L, Madara P, Del Pilar Cintron A, Wesley RA & Danner RL (2000). Superoxide production and reactive oxygen species signaling by endothelial nitric-oxide synthase. J Biol Chem 275, 16899-16903.
57. Westphal S, Taneva E, Kastner S, Martens-Lobenhoffer J, Gode-Boger S, Kropf S, Dierkes J & Luley C (2006). Endothelial dysfunction induced by postprandial lipemia is neutralized by addition of proteins to the fatty meal. Atherosclerosis 185, 313-319.
58. Yeh JL, Whitney EG, Lamb S & Brophy CM (1996). Nitric oxide is an autocrine feedback inhibitor of vascular smooth muscle contraction. Surgery 119, 104-109.
59. Zhang J, Li YD, Patel JM & Block ER (1998). Thioredoxin overexpression prevents NO-induced reduction of NO synthase activity in lung endothelial cells. Am J Physiol Lung Cell Mol Physiol 275, L288-L293.
60. Zou MH, Shi C & Cohen RA (2002). Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 109, 817-826.