메뉴 건너뛰기




Volumn 24, Issue 11, 2004, Pages 2028-2033

Hypochlorous acid impairs endothelium-derived nitric oxide bioactivity through a superoxide-dependent mechanism

Author keywords

Endothelium; Nitric oxide; Oxidant stress; Superoxide

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; ACETYLCHOLINE; ACETYLCYSTEINE; CALCIMYCIN; DIMER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYPOCHLOROUS ACID; LACTATE DEHYDROGENASE; METHIONINE; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE DONOR; OXIDIZING AGENT; SCAVENGER; SUPEROXIDE;

EID: 8344253531     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000143388.20994.fa     Document Type: Article
Times cited : (72)

References (44)
  • 2
    • 0027230446 scopus 로고
    • Dysfunction of vascular endothelium in diabetes mellitus
    • Cohen RA. Dysfunction of vascular endothelium in diabetes mellitus. Circulation. 1993;87:V67-V76.
    • (1993) Circulation , vol.87
    • Cohen, R.A.1
  • 4
    • 0024590132 scopus 로고
    • Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholestsrolemia and atherosclerosis
    • Shimokawa H, Vanhoutte PM. Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholestsrolemia and atherosclerosis. Circ Res. 1989;64:900-914.
    • (1989) Circ Res , vol.64 , pp. 900-914
    • Shimokawa, H.1    Vanhoutte, P.M.2
  • 6
    • 0037799889 scopus 로고    scopus 로고
    • Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease
    • Gokce N, Keaney JF Jr, Hunter LM, Watkins MT, Nedeljkovic ZS, Menzoian JO, Vita JA. Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease. J Am Coll Cardiol. 2003;41:1769-1775.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1769-1775
    • Gokce, N.1    Keaney Jr., J.F.2    Hunter, L.M.3    Watkins, M.T.4    Nedeljkovic, Z.S.5    Menzoian, J.O.6    Vita, J.A.7
  • 7
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 8
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA. 1990;87:1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 9
    • 0025989760 scopus 로고
    • Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits
    • Mugge A, Elwell JH, Peterson TE, Hofmeyer TG, Heistad DD, Harrison DG. Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits. Circ Res. 1991;69:1293-1300.
    • (1991) Circ Res , vol.69 , pp. 1293-1300
    • Mugge, A.1    Elwell, J.H.2    Peterson, T.E.3    Hofmeyer, T.G.4    Heistad, D.D.5    Harrison, D.G.6
  • 10
    • 0344043305 scopus 로고    scopus 로고
    • Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
    • Miller FJJ, Gutterman DD, Rios CD, Heistad DD, Davidson BL. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res. 1998;82:1298-1305.
    • (1998) Circ Res , vol.82 , pp. 1298-1305
    • Miller, F.J.J.1    Gutterman, D.D.2    Rios, C.D.3    Heistad, D.D.4    Davidson, B.L.5
  • 11
    • 0017240322 scopus 로고
    • Studies on the chlorinating activity of myeloperoxidase
    • Harrison JE, Schultz J. Studies on the chlorinating activity of myeloperoxidase. J Biol Chem. 1976;251:1371-1374.
    • (1976) J Biol Chem , vol.251 , pp. 1371-1374
    • Harrison, J.E.1    Schultz, J.2
  • 12
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
    • Daugherty A, Dunn JL, Rateri DL, Heinecke JW. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J Clin Invest. 1994;94:437-444.
    • (1994) J Clin Invest , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 13
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P. Macrophage myeloperoxidase regulation by granulocyte macrophage colony- stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol. 2001;158:879-891.
    • (2001) Am J Pathol , vol.158 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3    Virmani, R.4    Heinecke, J.W.5    Libby, P.6
  • 16
    • 0034534961 scopus 로고    scopus 로고
    • Nitric oxide is a physiological substrate for mammalian peroxidases
    • Abu-Soud HM, Hazen SL. Nitric oxide is a physiological substrate for mammalian peroxidases. J Biol Chem. 2000;275:37524-37532.
    • (2000) J Biol Chem , vol.275 , pp. 37524-37532
    • Abu-Soud, H.M.1    Hazen, S.L.2
  • 17
  • 18
    • 0030036853 scopus 로고    scopus 로고
    • Vascular incorporation of α-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation
    • Keaney JF Jr, Guo Y, Cunningham D, Shwaery GT, Xu A, Vila JA. Vascular incorporation of α-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation. J Clin Invest. 1996;98:386-394.
    • (1996) J Clin Invest , vol.98 , pp. 386-394
    • Keaney Jr., J.F.1    Guo, Y.2    Cunningham, D.3    Shwaery, G.T.4    Xu, A.5    Vila, J.A.6
  • 19
    • 0029056560 scopus 로고
    • Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
    • Keaney JF Jr, Xu A, Cunningham D, Jackson T, Frei B, Vita JA. Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation. J Clin Invest. 1995;95:2520-2529.
    • (1995) J Clin Invest , vol.95 , pp. 2520-2529
    • Keaney Jr., J.F.1    Xu, A.2    Cunningham, D.3    Jackson, T.4    Frei, B.5    Vita, J.A.6
  • 20
    • 0034625391 scopus 로고    scopus 로고
    • Ascorbic acid enhances endothelial nitric oxide synthase activity by increasing intracellular tetrahydrobiopterin
    • Huang A, Vita JA, Venema RC, Keaney JF Jr. Ascorbic acid enhances endothelial nitric oxide synthase activity by increasing intracellular tetrahydrobiopterin. J Biol Chem. 2000;275:17399-17406.
    • (2000) J Biol Chem , vol.275 , pp. 17399-17406
    • Huang, A.1    Vita, J.A.2    Venema, R.C.3    Keaney Jr., J.F.4
  • 21
    • 0037155131 scopus 로고    scopus 로고
    • Hydrogen peroxide activates endothelial nitric oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway
    • Thomas SR, Chen K, Keaney JF Jr. Hydrogen peroxide activates endothelial nitric oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. J Biol Chem. 2002;277:6017-6024.
    • (2002) J Biol Chem , vol.277 , pp. 6017-6024
    • Thomas, S.R.1    Chen, K.2    Keaney Jr., J.F.3
  • 24
    • 0031776230 scopus 로고    scopus 로고
    • Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite
    • Thomas SR, Davies MJ, Stocker R. Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite. Chem Res Toxicol. 1998;11:484-494.
    • (1998) Chem Res Toxicol , vol.11 , pp. 484-494
    • Thomas, S.R.1    Davies, M.J.2    Stocker, R.3
  • 25
    • 0002949575 scopus 로고
    • Endogenous antioxidant defences in human blood plasma
    • Sies H, ed. London, UK: Academic Press
    • Stocker R, Frei B. Endogenous antioxidant defences in human blood plasma. In: Sies H, ed. Oxidative Stress: Oxidants and Antioxidants. London, UK: Academic Press; 1991:213-243.
    • (1991) Oxidative Stress: Oxidants and Antioxidants , pp. 213-243
    • Stocker, R.1    Frei, B.2
  • 26
    • 0003698541 scopus 로고
    • Biological reactivity of hypochlorous acid: Implications for microbicidal mechanisms of leukocyte myeloperoxidase
    • Albrich JM, McCarthy CA, Hurst JK. Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase. Proc Natl Acad Sci USA. 1981;78:210-214.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 210-214
    • Albrich, J.M.1    McCarthy, C.A.2    Hurst, J.K.3
  • 27
    • 0021807129 scopus 로고
    • Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite
    • Winterboum CC. Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite. Biochim Biophys Acta. 1985;840:204-210.
    • (1985) Biochim Biophys Acta , vol.840 , pp. 204-210
    • Winterboum, C.C.1
  • 28
    • 0027516393 scopus 로고
    • Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages
    • Hazell LJ, Stocker R. Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages. Biochem J. 1993;290:165-172.
    • (1993) Biochem J , vol.290 , pp. 165-172
    • Hazell, L.J.1    Stocker, R.2
  • 30
    • 0034162772 scopus 로고    scopus 로고
    • Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein
    • Carr AC, Frei B. Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein. Biochem J. 2000;346:491-499.
    • (2000) Biochem J , vol.346 , pp. 491-499
    • Carr, A.C.1    Frei, B.2
  • 31
    • 0036199685 scopus 로고    scopus 로고
    • Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
    • Zou MH, Shi C, Cohen RA. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest. 2002;109:817-826.
    • (2002) J Clin Invest , vol.109 , pp. 817-826
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3
  • 32
    • 0001059250 scopus 로고    scopus 로고
    • 2/halide system in human atherosclerotic lesions: Colocalization of myeloperoxidase and hypochlorite-modified proteins
    • 2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins. Eur J Biochem. 2000;267:4495-4503.
    • (2000) Eur J Biochem , vol.267 , pp. 4495-4503
    • Malle, E.1    Waeg, G.2    Schreiber, R.3    Grone, E.F.4    Sattler, W.5    Grone, H.J.6
  • 33
    • 0030880306 scopus 로고    scopus 로고
    • α-tocopherol does not inhibit hypochlorite-induced oxidation of apolipoprotein B-100 of low-density lipoprotein
    • Hazell LJ, Stocker R. α-Tocopherol does not inhibit hypochlorite-induced oxidation of apolipoprotein B-100 of low-density lipoprotein. FEBS Lett. 1997;414:541-544.
    • (1997) FEBS Lett , vol.414 , pp. 541-544
    • Hazell, L.J.1    Stocker, R.2
  • 34
    • 0030979720 scopus 로고    scopus 로고
    • 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima
    • Hazen SL, Heinecke JW. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997;99:2075-2081.
    • (1997) J Clin Invest , vol.99 , pp. 2075-2081
    • Hazen, S.L.1    Heinecke, J.W.2
  • 35
    • 0034615999 scopus 로고    scopus 로고
    • p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima
    • Heller JI, Crowley JR, Hazen SL, Salvay DM, Wagner P, Pennathur S, Heinecke JW. p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima. J Biol Chem. 2000;275:9957-9962.
    • (2000) J Biol Chem , vol.275 , pp. 9957-9962
    • Heller, J.I.1    Crowley, J.R.2    Hazen, S.L.3    Salvay, D.M.4    Wagner, P.5    Pennathur, S.6    Heinecke, J.W.7
  • 37
    • 0032949778 scopus 로고    scopus 로고
    • Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages
    • Whitman SC, Hazen SL, Miller DB, Hegele RA, Heinecke JW, Huff MW. Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages. Arterioscler Thromb Vasc Biol. 1999;19:1238-1249.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1238-1249
    • Whitman, S.C.1    Hazen, S.L.2    Miller, D.B.3    Hegele, R.A.4    Heinecke, J.W.5    Huff, M.W.6
  • 38
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res. 2000;86:494-501.
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 39
    • 0035957931 scopus 로고    scopus 로고
    • Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase
    • Nuszkowski A, Grabner R, Marsche G, Unbehaun A, Malle E, Heller R. Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase. J Biol Chem. 2001;276:14212-14221.
    • (2001) J Biol Chem , vol.276 , pp. 14212-14221
    • Nuszkowski, A.1    Grabner, R.2    Marsche, G.3    Unbehaun, A.4    Malle, E.5    Heller, R.6
  • 41
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem. 1998;273:25804-25808.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 43
    • 0032510977 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy
    • Ushio-Fukai M, Alexander RW, Akers M, Griendling KK. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem. 1998;273:15022-15029.
    • (1998) J Biol Chem , vol.273 , pp. 15022-15029
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Griendling, K.K.4
  • 44
    • 0035844273 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves src-dependent EGF receptor transactivation
    • Chen K, Vita JA, Berk BC, Keaney JF Jr. c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves src-dependent EGF receptor transactivation. J Biol Chem 2001;276:16045-16050.
    • (2001) J Biol Chem , vol.276 , pp. 16045-16050
    • Chen, K.1    Vita, J.A.2    Berk, B.C.3    Keaney Jr., J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.