A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein

Biochemistry

Volumn 49, Issue 47, 2010, Pages 10061-10071

  Polishchuk, Alexei L ^a   Lear, James D ^a   Ma, Chunlong ^b   Lamb, Robert A ^b   Pinto, Lawrence H ^b   Degrado, William F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUSTABLE PARAMETERS; C-TERMINAL REGIONS; CONFORMATIONAL CHANGE; CONFORMATIONAL ENSEMBLE; CONFORMATIONAL STATE; CRYSTALLOGRAPHIC STRUCTURE; EXPERIMENTAL DATA; HIGH RESOLUTION; HIGH-RESOLUTION STRUCTURES; KINETIC MODELS; MECHANISTIC MODELS; MOLECULAR DYNAMICS CALCULATION; N-TERMINALS; OPTICAL SPECTROSCOPY; PH RANGE; PH VALUE; PH-DEPENDENT; PROTON AFFINITY; PROTON CONDUCTION; PROTON TRANSPORT; SOLVENT ACCESSIBILITY; STRUCTURAL INFORMATION; STRUCTURAL STATE; TRANS-MEMBRANE DOMAINS; TRANSITION MIDPOINT;

ACTIVATION ANALYSIS; DISTILLATION; LIPOSOMES; MAGNETIC DOMAINS; MAGNETIC RESONANCE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH EFFECTS; PHOSPHOLIPIDS; PROTEINS;

PROTONS;

PHOSPHOLIPID; PROTEIN M2;

ARTICLE; CONFORMATIONAL TRANSITION; ELECTROPHYSIOLOGY; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTON TRANSPORT;

ANIMALS; HYDROGEN-ION CONCENTRATION; INFLUENZA A VIRUS; ION CHANNELS; KINETICS; LIPOSOMES; OOCYTES; PROTEIN CONFORMATION; PROTONS; VIRAL MATRIX PROTEINS; XENOPUS;

EID: 78649500359     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101229m     Document Type: Article

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