-
1
-
-
0034727066
-
Multiple sclerosis
-
Noseworthy, J.H., Lucchinetti, C., Rodriguez, M., Weinshenker, B.G. Multiple sclerosis. N. Engl. J. Med., 2000, 343, 938-952.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 938-952
-
-
Noseworthy, J.H.1
Lucchinetti, C.2
Rodriguez, M.3
Weinshenker, B.G.4
-
2
-
-
34248359578
-
Natural history of multiple sclerosis: Risk factors and prognostic indicators
-
Vukusic, S., Confavreux, C. Natural history of multiple sclerosis: risk factors and prognostic indicators. Curr. Opin. Neurol., 2007, 20, 269-274.
-
(2007)
Curr. Opin. Neurol
, vol.20
, pp. 269-274
-
-
Vukusic, S.1
Confavreux, C.2
-
3
-
-
34548633861
-
Primary-progressive multiple sclerosis
-
Miller, D.H., Leary, S.M. Primary-progressive multiple sclerosis. Lancet Neurol., 2007, 6, 903-912.
-
(2007)
Lancet Neurol
, vol.6
, pp. 903-912
-
-
Miller, D.H.1
Leary, S.M.2
-
4
-
-
28544436950
-
Diagnostic criteria for multiple sclerosis: 2005 revisions to the McDonald Criteria
-
Polman, C.H., Reingold, S.C., Edan, G., Filippi, M., Hartung, H.P., Kappos, L., Lublin, F.D., Metz, L.M., McFarland, H.F., O'Connor, P.W., Sandberg-Wollheim, M., Thompson, A.J., Weinshenker, B.G., Wolinsky, J.S. Diagnostic criteria for multiple sclerosis: 2005 revisions to the McDonald Criteria. Ann. Neurol., 2005, 58, 840-846.
-
(2005)
Ann. Neurol
, vol.58
, pp. 840-846
-
-
Polman, C.H.1
Reingold, S.C.2
Edan, G.3
Filippi, M.4
Hartung, H.P.5
Kappos, L.6
Lublin, F.D.7
Metz, L.M.8
McFarland, H.F.9
O'Connor, P.W.10
Sandberg-Wollheim, M.11
Thompson, A.J.12
Weinshenker, B.G.13
Wolinsky, J.S.14
-
5
-
-
33244466021
-
Natural history of multiple sclerosis: A unifying concept
-
Confavreux, C., Vukusic, S. Natural history of multiple sclerosis: a unifying concept. Brain, 2006, 129, 606-616.
-
(2006)
Brain
, vol.129
, pp. 606-616
-
-
Confavreux, C.1
Vukusic, S.2
-
6
-
-
0034676548
-
Relapses and progression of disability in multiple sclerosis
-
Confavreux, C., Vukusic, S., Moreau, T., Adeleine, P. Relapses and progression of disability in multiple sclerosis. N. Engl. J. Med., 2000, 343, 1430-1438.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 1430-1438
-
-
Confavreux, C.1
Vukusic, S.2
Moreau, T.3
Adeleine, P.4
-
7
-
-
34548133584
-
Multiple sclerosis: A complicated picture of autoimmunity
-
McFarland, H.F., Martin, R. Multiple sclerosis: a complicated picture of autoimmunity. Nat. Immunol., 2007, 8, 913-919.
-
(2007)
Nat. Immunol
, vol.8
, pp. 913-919
-
-
McFarland, H.F.1
Martin, R.2
-
8
-
-
0036305186
-
Multiple sclerosis: Deeper understanding of its pathogenesis reveals new targets for therapy
-
Steinman, L., Martin, R., Bernard, C., Conlon, P., Oksenberg, J.R. Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy. Annu. Rev. Neurosci., 2002, 25, 491-505.
-
(2002)
Annu. Rev. Neurosci
, vol.25
, pp. 491-505
-
-
Steinman, L.1
Martin, R.2
Bernard, C.3
Conlon, P.4
Oksenberg, J.R.5
-
9
-
-
65249142200
-
The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease
-
Weiner, H.L. The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease? Ann. Neurol., 2009, 65, 239-248.
-
(2009)
Ann. Neurol
, vol.65
, pp. 239-248
-
-
Weiner, H.L.1
-
10
-
-
48249139449
-
Multiple sclerosis: An immune or neurodegenerative disorder?
-
Trapp, B.D., Nave, K.A. Multiple sclerosis: an immune or neurodegenerative disorder? Annu. Rev. Neurosci., 2008, 31, 247-269.
-
(2008)
Annu. Rev. Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
11
-
-
43249107238
-
Cortical pathology in multiple sclerosis
-
Stadelmann, C., Albert, M., Wegner, C., Bruck, W. Cortical pathology in multiple sclerosis. Curr. Opin. Neurol., 2008, 21, 229-234.
-
(2008)
Curr. Opin. Neurol
, vol.21
, pp. 229-234
-
-
Stadelmann, C.1
Albert, M.2
Wegner, C.3
Bruck, W.4
-
12
-
-
6944249912
-
Biomarkers and surrogate outcomes in neurode-generative disease: Lessons from multiple sclerosis
-
Miller, D.H. Biomarkers and surrogate outcomes in neurode-generative disease: lessons from multiple sclerosis. NeuroRx, 2004, 1, 284-294.
-
(2004)
NeuroRx
, vol.1
, pp. 284-294
-
-
Miller, D.H.1
-
13
-
-
0027503708
-
Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis
-
Katz, D., Taubenberger, J.K., Cannella, B., McFarlin, D.E., Raine, C.S., McFarland, H.F. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Ann. Neurol., 1993, 34, 661-669.
-
(1993)
Ann. Neurol
, vol.34
, pp. 661-669
-
-
Katz, D.1
Taubenberger, J.K.2
Cannella, B.3
McFarlin, D.E.4
Raine, C.S.5
McFarland, H.F.6
-
14
-
-
0030780349
-
Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology
-
Bruck, W., Bitsch, A., Kolenda, H., Bruck, Y., Stiefel, M., Lassmann, H. Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology. Ann. Neurol., 1997, 42, 783-793.
-
(1997)
Ann. Neurol
, vol.42
, pp. 783-793
-
-
Bruck, W.1
Bitsch, A.2
Kolenda, H.3
Bruck, Y.4
Stiefel, M.5
Lassmann, H.6
-
15
-
-
0025233883
-
Patterns of disease activity in multiple sclerosis: Clinical and magnetic resonance imaging study
-
Thompson, A.J., Kermode, A.G., MacManus, D.G., Kendall, B.E., Kingsley, D.P., Moseley, I.F., McDonald, W.I. Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study. BMJ, 1990, 300, 631-634.
-
(1990)
BMJ
, vol.300
, pp. 631-634
-
-
Thompson, A.J.1
Kermode, A.G.2
Macmanus, D.G.3
Kendall, B.E.4
Kingsley, D.P.5
Moseley, I.F.6
McDonald, W.I.7
-
16
-
-
0033586376
-
Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: A meta-analysis. Gadolinium MRI Meta-analysis Group
-
Kappos, L., Moeri, D., Radue, E.W., Schoetzau, A., Schweikert, K., Barkhof, F., Miller, D., Guttmann, C.R., Weiner, H.L., Gasperini, C., Filippi, M. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group. Lancet, 1999, 353, 964-969.
-
(1999)
Lancet
, vol.353
, pp. 964-969
-
-
Kappos, L.1
Moeri, D.2
Radue, E.W.3
Schoetzau, A.4
Schweikert, K.5
Barkhof, F.6
Miller, D.7
Guttmann, C.R.8
Weiner, H.L.9
Gasperini, C.10
Filippi, M.11
-
17
-
-
0037122957
-
A longitudinal study of abnormalities on MRI and disability from multiple sclerosis
-
Brex, P.A., Ciccarelli, O., O'Riordan, J.I., Sailer, M., Thompson, A.J., Miller, D.H. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. N. Engl. J. Med., 2002, 346, 158-164.
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 158-164
-
-
Brex, P.A.1
Ciccarelli, O.2
O'Riordan, J.I.3
Sailer, M.4
Thompson, A.J.5
Miller, D.H.6
-
18
-
-
0033551457
-
A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)
-
Simon, J.H., Jacobs, L.D., Campion, M.K., Rudick, R.A., Cookfair, D.L., Herndon, R.M., Richert, J.R., Salazar, A.M., Fischer, J.S., Goodkin, D.E., Simonian, N., Lajaunie, M., Miller, D.E., Wende, K., Martens-Davidson, A., Kinkel, R.P., Munschauer, F.E., 3rd, Brownscheidle, C.M. A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology, 1999, 53, 139-148.
-
(1999)
Neurology
, vol.53
, pp. 139-148
-
-
Simon, J.H.1
Jacobs, L.D.2
Campion, M.K.3
Rudick, R.A.4
Cookfair, D.L.5
Herndon, R.M.6
Richert, J.R.7
Salazar, A.M.8
Fischer, J.S.9
Goodkin, D.E.10
Simonian, N.11
Lajaunie, M.12
Miller, D.E.13
Wende, K.14
Martens-Davidson, A.15
Kinkel, R.P.16
Munschauer III, F.E.17
Brownscheidle, C.M.18
-
19
-
-
0035833970
-
Optimizing the association between disability and biological markers in MS
-
Kalkers, N.F., Bergers, E., Castelijns, J.A., van Walderveen, M.A., Bot, J.C., Ader, H.J., Polman, C.H., Barkhof, F. Optimizing the association between disability and biological markers in MS. Neurology, 2001, 57, 1253-1258.
-
(2001)
Neurology
, vol.57
, pp. 1253-1258
-
-
Kalkers, N.F.1
Bergers, E.2
Castelijns, J.A.3
van Walderveen, M.A.4
Bot, J.C.5
Ader, H.J.6
Polman, C.H.7
Barkhof, F.8
-
20
-
-
0031962941
-
Imaging axonal damage of normal-appearing white matter in multiple sclerosis
-
Fu, L., Matthews, P.M., De Stefano, N., Worsley, K.J., Narayanan, S., Francis, G.S., Antel, J.P., Wolfson, C., Arnold, D.L. Imaging axonal damage of normal-appearing white matter in multiple sclerosis. Brain, 1998, 121 (Pt 1), 103-113.
-
(1998)
Brain
, vol.121
, Issue.PART 1
, pp. 103-113
-
-
Fu, L.1
Matthews, P.M.2
de Stefano, N.3
Worsley, K.J.4
Narayanan, S.5
Francis, G.S.6
Antel, J.P.7
Wolfson, C.8
Arnold, D.L.9
-
21
-
-
0030609055
-
1H magnetic resonance spectroscopy of chronic cerebral white matter lesions and normal appearing white matter in multiple sclerosis
-
Davie, C.A., Barker, G.J., Thompson, A.J., Tofts, P.S., McDonald, W.I., Miller, D.H. 1H magnetic resonance spectroscopy of chronic cerebral white matter lesions and normal appearing white matter in multiple sclerosis. J. Neurol. Neurosurg. Psychiatry, 1997, 63, 736-742.
-
(1997)
J. Neurol. Neurosurg. Psychiatry
, vol.63
, pp. 736-742
-
-
Davie, C.A.1
Barker, G.J.2
Thompson, A.J.3
Tofts, P.S.4
McDonald, W.I.5
Miller, D.H.6
-
22
-
-
0033663894
-
Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients
-
Bjartmar, C., Kidd, G., Mork, S., Rudick, R., Trapp, B.D. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann. Neurol., 2000, 48, 893-901.
-
(2000)
Ann. Neurol
, vol.48
, pp. 893-901
-
-
Bjartmar, C.1
Kidd, G.2
Mork, S.3
Rudick, R.4
Trapp, B.D.5
-
23
-
-
0037469191
-
Multiple sclerosis: Neurofilament light chain antibodies are correlated to cerebral atrophy
-
Eikelenboom, M.J., Petzold, A., Lazeron, R.H., Silber, E., Sharief, M., Thompson, E.J., Barkhof, F., Giovannoni, G., Polman, C.H., Uitdehaag, B.M. Multiple sclerosis: Neurofilament light chain antibodies are correlated to cerebral atrophy. Neurology, 2003, 60, 219-223.
-
(2003)
Neurology
, vol.60
, pp. 219-223
-
-
Eikelenboom, M.J.1
Petzold, A.2
Lazeron, R.H.3
Silber, E.4
Sharief, M.5
Thompson, E.J.6
Barkhof, F.7
Giovannoni, G.8
Polman, C.H.9
Uitdehaag, B.M.10
-
24
-
-
15944409728
-
Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss
-
Petzold, A. Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss. J. Neurol. Sci., 2005, 233, 183-198.
-
(2005)
J. Neurol. Sci
, vol.233
, pp. 183-198
-
-
Petzold, A.1
-
25
-
-
45549092100
-
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis
-
Oksenberg, J.R., Baranzini, S.E., Sawcer, S., Hauser, S.L. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat. Rev. Genet., 2008, 9, 516-526.
-
(2008)
Nat. Rev. Genet
, vol.9
, pp. 516-526
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
Sawcer, S.3
Hauser, S.L.4
-
26
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager, P.L., Jia, X., Wang, J., de Bakker, P.I., Ottoboni, L., Aggarwal, N.T., Piccio, L., Raychaudhuri, S., Tran, D., Aubin, C., Briskin, R., Romano, S., Baranzini, S.E., McCauley, J.L., Pericak-Vance, M.A., Haines, J.L., Gibson, R.A., Naeglin, Y., Uitdehaag, B., Matthews, P.M., Kappos, L., Polman, C., McArdle, W.L., Strachan, D.P., Evans, D., Cross, A.H., Daly, M.J., Compston, A., Sawcer, S.J., Weiner, H.L., Hauser, S.L., Hafler, D.A., Oksenberg, J.R. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat. Genet., 2009, 41, 776-782.
-
(2009)
Nat. Genet
, vol.41
, pp. 776-782
-
-
de Jager, P.L.1
Jia, X.2
Wang, J.3
de Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
Piccio, L.7
Raychaudhuri, S.8
Tran, D.9
Aubin, C.10
Briskin, R.11
Romano, S.12
Baranzini, S.E.13
McCauley, J.L.14
Pericak-Vance, M.A.15
Haines, J.L.16
Gibson, R.A.17
Naeglin, Y.18
Uitdehaag, B.19
Matthews, P.M.20
Kappos, L.21
Polman, C.22
McArdle, W.L.23
Strachan, D.P.24
Evans, D.25
Cross, A.H.26
Daly, M.J.27
Compston, A.28
Sawcer, S.J.29
Weiner, H.L.30
Hauser, S.L.31
Hafler, D.A.32
Oksenberg, J.R.33
more..
-
27
-
-
67649881102
-
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
-
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat. Genet., 2009, 41, 824-828.
-
(2009)
Nat. Genet
, vol.41
, pp. 824-828
-
-
-
28
-
-
0031002545
-
Axonal damage in acute multiple sclerosis lesions
-
Ferguson, B., Matyszak, M.K., Esiri, M.M., Perry, V.H. Axonal damage in acute multiple sclerosis lesions. Brain, 1997, 120(Pt 3), 393-399.
-
(1997)
Brain
, vol.120
, Issue.PART 3
, pp. 393-399
-
-
Ferguson, B.1
Matyszak, M.K.2
Esiri, M.M.3
Perry, V.H.4
-
29
-
-
0032576752
-
Axonal transection in the lesions of multiple sclerosis
-
Trapp, B.D., Peterson, J., Ransohoff, R.M., Rudick, R., Mork, S., Bo, L. Axonal transection in the lesions of multiple sclerosis. N. Engl. J. Med., 1998, 338, 278-285.
-
(1998)
N. Engl. J. Med
, vol.338
, pp. 278-285
-
-
Trapp, B.D.1
Peterson, J.2
Ransohoff, R.M.3
Rudick, R.4
Mork, S.5
Bo, L.6
-
30
-
-
0033870097
-
Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
-
Kornek, B., Storch, M.K., Weissert, R., Wallstroem, E., Stefferl, A., Olsson, T., Linington, C., Schmidbauer, M., Lassmann, H. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am. J. Pathol., 2000, 157, 267-276.
-
(2000)
Am. J. Pathol
, vol.157
, pp. 267-276
-
-
Kornek, B.1
Storch, M.K.2
Weissert, R.3
Wallstroem, E.4
Stefferl, A.5
Olsson, T.6
Linington, C.7
Schmidbauer, M.8
Lassmann, H.9
-
31
-
-
0026580004
-
Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells
-
de Waegh, S.M., Lee, V.M., Brady, S.T. Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell, 1992, 68, 451-463.
-
(1992)
Cell
, vol.68
, pp. 451-463
-
-
de Waegh, S.M.1
Lee, V.M.2
Brady, S.T.3
-
32
-
-
11244309560
-
Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis
-
Schneider, A., Araujo, G.W., Trajkovic, K., Herrmann, M.M., Merkler, D., Mandelkow, E.M., Weissert, R., Simons, M. Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis. J. Biol. Chem., 2004, 279, 55833-55839.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55833-55839
-
-
Schneider, A.1
Araujo, G.W.2
Trajkovic, K.3
Herrmann, M.M.4
Merkler, D.5
Mandelkow, E.M.6
Weissert, R.7
Simons, M.8
-
33
-
-
64449088756
-
Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis
-
Anderson, J.M., Patani, R., Reynolds, R., Nicholas, R., Compston, A., Spillantini, M.G., Chandran, S. Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis. Acta Neuropathol., 2009, 117, 583-589.
-
(2009)
Acta Neuropathol
, vol.117
, pp. 583-589
-
-
Anderson, J.M.1
Patani, R.2
Reynolds, R.3
Nicholas, R.4
Compston, A.5
Spillantini, M.G.6
Chandran, S.7
-
34
-
-
42449141602
-
Cytoskeletal protein carbonylation and degradation in experimental autoimmune encephalomyelitis
-
Smerjac, S.M., Bizzozero, O.A. Cytoskeletal protein carbonylation and degradation in experimental autoimmune encephalomyelitis. J. Neurochem., 2008, 105, 763-772.
-
(2008)
J. Neurochem
, vol.105
, pp. 763-772
-
-
Smerjac, S.M.1
Bizzozero, O.A.2
-
35
-
-
0038459134
-
Molecular mechanisms of axonal damage in inflammatory central nervous system diseases
-
Neumann, H. Molecular mechanisms of axonal damage in inflammatory central nervous system diseases. Curr. Opin. Neurol., 2003, 16, 267-273.
-
(2003)
Curr. Opin. Neurol
, vol.16
, pp. 267-273
-
-
Neumann, H.1
-
36
-
-
0036788406
-
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time 10.1093/brain/awf235
-
Kuhlmann, T., Lingfeld, G., Bitsch, A., Schuchardt, J., Bruck, W. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time 10.1093/brain/awf235. Brain, 2002, 125, 2202-2212.
-
(2002)
Brain
, vol.125
, pp. 2202-2212
-
-
Kuhlmann, T.1
Lingfeld, G.2
Bitsch, A.3
Schuchardt, J.4
Bruck, W.5
-
37
-
-
66549130329
-
The relation between inflammation and neurode-generation in multiple sclerosis brains
-
Frischer, J.M., Bramow, S., Dal-Bianco, A., Lucchinetti, C.F., Rauschka, H., Schmidbauer, M., Laursen, H., Sorensen, P.S., Lassmann, H. The relation between inflammation and neurode-generation in multiple sclerosis brains. Brain, 2009, 132, 1175-1189.
-
(2009)
Brain
, vol.132
, pp. 1175-1189
-
-
Frischer, J.M.1
Bramow, S.2
Dal-Bianco, A.3
Lucchinetti, C.F.4
Rauschka, H.5
Schmidbauer, M.6
Laursen, H.7
Sorensen, P.S.8
Lassmann, H.9
-
38
-
-
0036161001
-
Brain atrophy in clinically early relapsing-remitting multiple sclerosis
-
Chard, D.T., Griffin, C.M., Parker, G.J., Kapoor, R., Thompson, A.J., Miller, D.H. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain, 2002, 125, 327-337.
-
(2002)
Brain
, vol.125
, pp. 327-337
-
-
Chard, D.T.1
Griffin, C.M.2
Parker, G.J.3
Kapoor, R.4
Thompson, A.J.5
Miller, D.H.6
-
39
-
-
0031054508
-
Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: Differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha
-
Neumann, H., Schmidt, H., Cavalie, A., Jenne, D., Wekerle, H. Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha. J. Exp. Med., 1997, 185, 305-316.
-
(1997)
J. Exp. Med
, vol.185
, pp. 305-316
-
-
Neumann, H.1
Schmidt, H.2
Cavalie, A.3
Jenne, D.4
Wekerle, H.5
-
40
-
-
0034790728
-
In vivo expression of major histocompatibility complex molecules on oligodendrocytes and neurons during viral infection
-
Redwine, J.M., Buchmeier, M.J., Evans, C.F. In vivo expression of major histocompatibility complex molecules on oligodendrocytes and neurons during viral infection. Am. J.Pathol., 2001, 159, 1219-1224.
-
(2001)
Am. J.Pathol
, vol.159
, pp. 1219-1224
-
-
Redwine, J.M.1
Buchmeier, M.J.2
Evans, C.F.3
-
41
-
-
0034842960
-
Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes
-
Medana, I., Martinic, M.A., Wekerle, H., Neumann, H. Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am. J. Pathol., 2001, 159, 809-815.
-
(2001)
Am. J. Pathol
, vol.159
, pp. 809-815
-
-
Medana, I.1
Martinic, M.A.2
Wekerle, H.3
Neumann, H.4
-
42
-
-
23444434940
-
Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy?
-
Friese, M.A., Fugger, L. Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain, 2005, 128, 1747-1763.
-
(2005)
Brain
, vol.128
, pp. 1747-1763
-
-
Friese, M.A.1
Fugger, L.2
-
43
-
-
0345432117
-
Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis
-
Rivera-Quinones, C., McGavern, D., Schmelzer, J.D., Hunter, S.F., Low, P.A., Rodriguez, M. Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis. Nat. Med., 1998, 4, 187-193.
-
(1998)
Nat. Med
, vol.4
, pp. 187-193
-
-
Rivera-Quinones, C.1
McGavern, D.2
Schmelzer, J.D.3
Hunter, S.F.4
Low, P.A.5
Rodriguez, M.6
-
44
-
-
35548986304
-
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
-
Hanisch, U.K., Kettenmann, H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci., 2007, 10, 1387-1394.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.K.1
Kettenmann, H.2
-
45
-
-
0013292906
-
The role of nitric oxide in multiple sclerosis
-
Smith, K.J., Lassmann, H. The role of nitric oxide in multiple sclerosis. Lancet Neurol., 2002, 1, 232-241.
-
(2002)
Lancet Neurol
, vol.1
, pp. 232-241
-
-
Smith, K.J.1
Lassmann, H.2
-
46
-
-
0036095995
-
Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation
-
Renganathan, M., Cummins, T.R., Waxman, S.G. Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation. J. Neurophysiol., 2002, 87, 761-775.
-
(2002)
J. Neurophysiol
, vol.87
, pp. 761-775
-
-
Renganathan, M.1
Cummins, T.R.2
Waxman, S.G.3
-
47
-
-
12144264780
-
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide
-
Stagi, M., Dittrich, P.S., Frank, N., Iliev, A.I., Schwille, P., Neumann, H. Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide. J. Neurosci., 2005, 25, 352-362.
-
(2005)
J. Neurosci
, vol.25
, pp. 352-362
-
-
Stagi, M.1
Dittrich, P.S.2
Frank, N.3
Iliev, A.I.4
Schwille, P.5
Neumann, H.6
-
48
-
-
0027973242
-
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains
-
Bo, L., Dawson, T.M., Wesselingh, S., Mork, S., Choi, S., Kong, P.A., Hanley, D., Trapp, B.D. Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol., 1994, 36, 778-786.
-
(1994)
Ann. Neurol
, vol.36
, pp. 778-786
-
-
Bo, L.1
Dawson, T.M.2
Wesselingh, S.3
Mork, S.4
Choi, S.5
Kong, P.A.6
Hanley, D.7
Trapp, B.D.8
-
49
-
-
0034965383
-
Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions
-
Liu, J.S., Zhao, M.L., Brosnan, C.F., Lee, S.C. Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions. Am. J. Pathol., 2001, 158, 2057-2066.
-
(2001)
Am. J. Pathol
, vol.158
, pp. 2057-2066
-
-
Liu, J.S.1
Zhao, M.L.2
Brosnan, C.F.3
Lee, S.C.4
-
50
-
-
0033958462
-
Glutamate excitotoxicity in a model of multiple sclerosis
-
Pitt, D., Werner, P., Raine, C.S. Glutamate excitotoxicity in a model of multiple sclerosis. Nat. Med., 2000, 6, 67-70.
-
(2000)
Nat. Med
, vol.6
, pp. 67-70
-
-
Pitt, D.1
Werner, P.2
Raine, C.S.3
-
51
-
-
63849213783
-
Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis
-
Centonze, D., Muzio, L., Rossi, S., Cavasinni, F., De Chiara, V., Bergami, A., Musella, A., D'Amelio, M., Cavallucci, V., Martorana, A., Bergamaschi, A., Cencioni, M.T., Diamantini, A., Butti, E., Comi, G., Bernardi, G., Cecconi, F., Battistini, L., Furlan, R., Martino, G. Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis. J. Neurosci., 2009, 29, 3442-3452.
-
(2009)
J. Neurosci
, vol.29
, pp. 3442-3452
-
-
Centonze, D.1
Muzio, L.2
Rossi, S.3
Cavasinni, F.4
de Chiara, V.5
Bergami, A.6
Musella, A.7
D'Amelio, M.8
Cavallucci, V.9
Martorana, A.10
Bergamaschi, A.11
Cencioni, M.T.12
Diamantini, A.13
Butti, E.14
Comi, G.15
Bernardi, G.16
Cecconi, F.17
Battistini, L.18
Furlan, R.19
Martino, G.20
more..
-
52
-
-
0033963231
-
Autoimmune encephalomyelitis ameliorated by AMPA antagonists
-
Smith, T., Groom, A., Zhu, B., Turski, L. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat. Med., 2000, 6, 62-66.
-
(2000)
Nat. Med
, vol.6
, pp. 62-66
-
-
Smith, T.1
Groom, A.2
Zhu, B.3
Turski, L.4
-
53
-
-
29244483141
-
NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
-
Salter, M.G., Fern, R. NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature, 2005, 438, 1167-1171.
-
(2005)
Nature
, vol.438
, pp. 1167-1171
-
-
Salter, M.G.1
Fern, R.2
-
54
-
-
29244440745
-
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
-
Karadottir, R., Cavelier, P., Bergersen, L.H., Attwell, D. NMDA receptors are expressed in oligodendrocytes and activated in ischaemia. Nature, 2005, 438, 1162-1166.
-
(2005)
Nature
, vol.438
, pp. 1162-1166
-
-
Karadottir, R.1
Cavelier, P.2
Bergersen, L.H.3
Attwell, D.4
-
55
-
-
34948864286
-
Neurofascin as a novel target for autoantibodymediated axonal injury
-
Mathey, E.K., Derfuss, T., Storch, M.K., Williams, K.R., Hales, K., Woolley, D.R., Al-Hayani, A., Davies, S.N., Rasband, M.N., Olsson, T., Moldenhauer, A., Velhin, S., Hohlfeld, R., Meinl, E., Linington, C. Neurofascin as a novel target for autoantibodymediated axonal injury. J. Exp. Med., 2007, 204, 2363-2372.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2363-2372
-
-
Mathey, E.K.1
Derfuss, T.2
Storch, M.K.3
Williams, K.R.4
Hales, K.5
Woolley, D.R.6
Al-Hayani, A.7
Davies, S.N.8
Rasband, M.N.9
Olsson, T.10
Moldenhauer, A.11
Velhin, S.12
Hohlfeld, R.13
Meinl, E.14
Linington, C.15
-
56
-
-
66249105681
-
Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals
-
Derfuss, T., Parikh, K., Velhin, S., Braun, M., Mathey, E., Krumbholz, M., Kumpfel, T., Moldenhauer, A., Rader, C., Sonderegger, P., Pollmann, W., Tiefenthaller, C., Bauer, J., Lassmann, H., Wekerle, H., Karagogeos, D., Hohlfeld, R., Linington, C., Meinl, E. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proc. Natl. Acad. Sci. USA, 2009, 106, 8302-8307.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8302-8307
-
-
Derfuss, T.1
Parikh, K.2
Velhin, S.3
Braun, M.4
Mathey, E.5
Krumbholz, M.6
Kumpfel, T.7
Moldenhauer, A.8
Rader, C.9
Sonderegger, P.10
Pollmann, W.11
Tiefenthaller, C.12
Bauer, J.13
Lassmann, H.14
Wekerle, H.15
Karagogeos, D.16
Hohlfeld, R.17
Linington, C.18
Meinl, E.19
-
57
-
-
67049158616
-
Epstein-Barr virus and multiple sclerosis
-
Salvetti, M., Giovannoni, G., Aloisi, F. Epstein-Barr virus and multiple sclerosis. Curr. Opin. Neurol., 2009, 22, 201-206.
-
(2009)
Curr. Opin. Neurol
, vol.22
, pp. 201-206
-
-
Salvetti, M.1
Giovannoni, G.2
Aloisi, F.3
-
58
-
-
61849179617
-
The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: A biological interface between virology, genetics, and immunology in human physiology and disease
-
Dolei, A., Perron, H. The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease. J. Neurovirol., 2009, 15, 4-13.
-
(2009)
J. Neurovirol
, vol.15
, pp. 4-13
-
-
Dolei, A.1
Perron, H.2
-
59
-
-
66549118688
-
Mitochondrial changes within axons in multiple sclerosis
-
Mahad, D.J., Ziabreva, I., Campbell, G., Lax, N., White, K., Hanson, P.S., Lassmann, H., Turnbull, D.M. Mitochondrial changes within axons in multiple sclerosis. Brain, 2009, 132, 1161-1174.
-
(2009)
Brain
, vol.132
, pp. 1161-1174
-
-
Mahad, D.J.1
Ziabreva, I.2
Campbell, G.3
Lax, N.4
White, K.5
Hanson, P.S.6
Lassmann, H.7
Turnbull, D.M.8
-
60
-
-
70349135156
-
Enhanced number and activity of mitochondria in multiple sclerosis lesions
-
Witte, M.E., Bo, L., Rodenburg, R.J., Belien, J.A., Musters, R., Hazes, T., Wintjes, L.T., Smeitink, J.A., Geurts, J.J., De Vries, H.E., van der Valk, P., van Horssen, J. Enhanced number and activity of mitochondria in multiple sclerosis lesions. J. Pathol., 2009, 219, 193-204.
-
(2009)
J. Pathol
, vol.219
, pp. 193-204
-
-
Witte, M.E.1
Bo, L.2
Rodenburg, R.J.3
Belien, J.A.4
Musters, R.5
Hazes, T.6
Wintjes, L.T.7
Smeitink, J.A.8
Geurts, J.J.9
de Vries, H.E.10
van der Valk, P.11
van Horssen, J.12
-
61
-
-
68449092498
-
Axonal degeneration in multiple sclerosis: The mitochondrial hypothesis
-
Su, K.G., Banker, G., Bourdette, D., Forte, M. Axonal degeneration in multiple sclerosis: the mitochondrial hypothesis. Curr. Neurol. Neurosci. Rep., 2009, 9, 411-417.
-
(2009)
Curr. Neurol. Neurosci. Rep
, vol.9
, pp. 411-417
-
-
Su, K.G.1
Banker, G.2
Bourdette, D.3
Forte, M.4
-
62
-
-
33947509525
-
The immunopathology of multiple sclerosis: An overview
-
Lassmann, H., Bruck, W., Lucchinetti, C.F. The immunopathology of multiple sclerosis: an overview. Brain Pathol., 2007, 17, 210-218.
-
(2007)
Brain Pathol
, vol.17
, pp. 210-218
-
-
Lassmann, H.1
Bruck, W.2
Lucchinetti, C.F.3
-
63
-
-
2442708947
-
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
-
Serafini, B., Rosicarelli, B., Magliozzi, R., Stigliano, E., Aloisi, F. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol., 2004, 14, 164-174.
-
(2004)
Brain Pathol
, vol.14
, pp. 164-174
-
-
Serafini, B.1
Rosicarelli, B.2
Magliozzi, R.3
Stigliano, E.4
Aloisi, F.5
-
64
-
-
0037828315
-
Subpial demyelination in the cerebral cortex of multiple sclerosis patients
-
Bo, L., Vedeler, C.A., Nyland, H.I., Trapp, B.D., Mork, S.J. Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J. Neuropathol. Exp. Neurol., 2003, 62, 723-732.
-
(2003)
J. Neuropathol. Exp. Neurol
, vol.62
, pp. 723-732
-
-
Bo, L.1
Vedeler, C.A.2
Nyland, H.I.3
Trapp, B.D.4
Mork, S.J.5
-
65
-
-
47249163192
-
Lymphoid chemokines in chronic neuroinflammation
-
Aloisi, F., Columba-Cabezas, S., Franciotta, D., Rosicarelli, B., Magliozzi, R., Reynolds, R., Ambrosini, E., Coccia, E., Salvetti, M., Serafini, B. Lymphoid chemokines in chronic neuroinflammation. J. Neuroimmunol. Chemokines Chemokine Recept. Nervous Syst., 2008, 198, 106-112.
-
(2008)
J. Neuroimmunol. Chemokines Chemokine Recept. Nervous Syst
, vol.198
, pp. 106-112
-
-
Aloisi, F.1
Columba-Cabezas, S.2
Franciotta, D.3
Rosicarelli, B.4
Magliozzi, R.5
Reynolds, R.6
Ambrosini, E.7
Coccia, E.8
Salvetti, M.9
Serafini, B.10
-
66
-
-
0032935470
-
Cortical lesions in multiple sclerosis
-
Kidd, D., Barkhof, F., McConnell, R., Algra, P.R., Allen, I.V., Revesz, T. Cortical lesions in multiple sclerosis. Brain, 1999, 122 (Pt 1), 17-26.
-
(1999)
Brain
, vol.122
, Issue.PART 1
, pp. 17-26
-
-
Kidd, D.1
Barkhof, F.2
McConnell, R.3
Algra, P.R.4
Allen, I.V.5
Revesz, T.6
-
67
-
-
0034842126
-
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
-
Peterson, J.W., Bo, L., Mork, S., Chang, A., Trapp, B.D. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann. Neurol., 2001, 50, 389-400.
-
(2001)
Ann. Neurol
, vol.50
, pp. 389-400
-
-
Peterson, J.W.1
Bo, L.2
Mork, S.3
Chang, A.4
Trapp, B.D.5
-
68
-
-
27644552194
-
Cortical demyelination and diffuse white matter injury in multiple sclerosis
-
Kutzelnigg, A., Lucchinetti, C.F., Stadelmann, C., Bruck, W., Rauschka, H., Bergmann, M., Schmidbauer, M., Parisi, J.E., Lassmann, H. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain, 2005, 128, 2705-2712.
-
(2005)
Brain
, vol.128
, pp. 2705-2712
-
-
Kutzelnigg, A.1
Lucchinetti, C.F.2
Stadelmann, C.3
Bruck, W.4
Rauschka, H.5
Bergmann, M.6
Schmidbauer, M.7
Parisi, J.E.8
Lassmann, H.9
-
69
-
-
33748510173
-
Innate immunity in multiple sclerosis: Myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response
-
Karni, A., Abraham, M., Monsonego, A., Cai, G., Freeman, G.J., Hafler, D., Khoury, S.J., Weiner, H.L. Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response. J. Immunol., 2006, 177, 4196-4202.
-
(2006)
J. Immunol
, vol.177
, pp. 4196-4202
-
-
Karni, A.1
Abraham, M.2
Monsonego, A.3
Cai, G.4
Freeman, G.J.5
Hafler, D.6
Khoury, S.J.7
Weiner, H.L.8
-
70
-
-
0020509790
-
Characterization of cloned cDNA representing rat myelin basic protein: Absence of expression in brain of shiverer mutant mice
-
Roach, A., Boylan, K., Horvath, S., Prusiner, S.B., Hood, L.E. Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice. Cell, 1983, 34, 799-806.
-
(1983)
Cell
, vol.34
, pp. 799-806
-
-
Roach, A.1
Boylan, K.2
Horvath, S.3
Prusiner, S.B.4
Hood, L.E.5
-
71
-
-
0035313624
-
Changes in microtubule stability and density in myelin-deficient shiverer mouse CNS axons
-
Kirkpatrick, L.L., Witt, A.S., Payne, H.R., Shine, H.D., Brady, S.T. Changes in microtubule stability and density in myelin-deficient shiverer mouse CNS axons. J. Neurosci., 2001, 21, 2288-2297.
-
(2001)
J. Neurosci
, vol.21
, pp. 2288-2297
-
-
Kirkpatrick, L.L.1
Witt, A.S.2
Payne, H.R.3
Shine, H.D.4
Brady, S.T.5
-
72
-
-
43249098296
-
Axon-glial signaling and the glial support of axon function
-
Nave, K.A., Trapp, B.D. Axon-glial signaling and the glial support of axon function. Annu. Rev. Neurosci., 2008, 31, 535-561.
-
(2008)
Annu. Rev. Neurosci
, vol.31
, pp. 535-561
-
-
Nave, K.A.1
Trapp, B.D.2
-
73
-
-
33751514940
-
Neuron-glia communication in the control of oligodendrocyte function and myelin biogenesis
-
Simons, M., Trajkovic, K. Neuron-glia communication in the control of oligodendrocyte function and myelin biogenesis. J. Cell Sci., 2006, 119, 4381-4389.
-
(2006)
J. Cell Sci
, vol.119
, pp. 4381-4389
-
-
Simons, M.1
Trajkovic, K.2
-
74
-
-
0037370361
-
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
-
Lappe-Siefke, C., Goebbels, S., Gravel, M., Nicksch, E., Lee, J., Braun, P.E., Griffiths, I.R., Nave, K.A. Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat. Genet., 2003, 33, 366-374.
-
(2003)
Nat. Genet
, vol.33
, pp. 366-374
-
-
Lappe-Siefke, C.1
Goebbels, S.2
Gravel, M.3
Nicksch, E.4
Lee, J.5
Braun, P.E.6
Griffiths, I.R.7
Nave, K.A.8
-
75
-
-
0032486428
-
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
-
Griffiths, I., Klugmann, M., Anderson, T., Yool, D., Thomson, C., Schwab, M.H., Schneider, A., Zimmermann, F., McCulloch, M., Nadon, N., Nave, K.A. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science, 1998, 280, 1610-1613.
-
(1998)
Science
, vol.280
, pp. 1610-1613
-
-
Griffiths, I.1
Klugmann, M.2
Anderson, T.3
Yool, D.4
Thomson, C.5
Schwab, M.H.6
Schneider, A.7
Zimmermann, F.8
McCulloch, M.9
Nadon, N.10
Nave, K.A.11
-
76
-
-
0028276189
-
Myelination in the absence of myelin-associated glycoprotein
-
Li, C., Tropak, M.B., Gerlai, R., Clapoff, S., Abramow-Newerly, W., Trapp, B., Peterson, A., Roder, J. Myelination in the absence of myelin-associated glycoprotein. Nature, 1994, 369, 747-750.
-
(1994)
Nature
, vol.369
, pp. 747-750
-
-
Li, C.1
Tropak, M.B.2
Gerlai, R.3
Clapoff, S.4
Abramow-Newerly, W.5
Trapp, B.6
Peterson, A.7
Roder, J.8
-
77
-
-
0141987863
-
Polarized domains of myelinated axons
-
Salzer, J.L. Polarized domains of myelinated axons. Neuron, 2003,40, 297-318.
-
(2003)
Neuron
, vol.40
, pp. 297-318
-
-
Salzer, J.L.1
-
78
-
-
0033749676
-
Molecular domains of myelinated axons
-
Peles, E., Salzer, J.L. Molecular domains of myelinated axons. Curr. Opin. Neurobiol., 2000, 10, 558-565.
-
(2000)
Curr. Opin. Neurobiol
, vol.10
, pp. 558-565
-
-
Peles, E.1
Salzer, J.L.2
-
79
-
-
40549135991
-
Mechanisms of disease: Sodium channels and neuroprotection in multiple sclerosis-current status
-
Waxman, S.G. Mechanisms of disease: sodium channels and neuroprotection in multiple sclerosis-current status. Nat. Clin. Pract. Neurol., 2008, 4, 159-169.
-
(2008)
Nat. Clin. Pract. Neurol
, vol.4
, pp. 159-169
-
-
Waxman, S.G.1
-
80
-
-
0030787862
-
Distribution of sodium channels in chronically demyelinated spinal cord axons: Immunoultrastructural localization and electro-physiological observations
-
Black, J.A., Felts, P., Smith, K.J., Kocsis, J.D., Waxman, S.G. Distribution of sodium channels in chronically demyelinated spinal cord axons: immunoultrastructural localization and electro-physiological observations. Brain Res., 1997, 761, 1.
-
(1997)
Brain Res
, vol.761
, pp. 1
-
-
Black, J.A.1
Felts, P.2
Smith, K.J.3
Kocsis, J.D.4
Waxman, S.G.5
-
81
-
-
0030767405
-
Conduction in segmentally demyelinated mammalian central axons
-
Felts, P.A., Baker, T.A., Smith, K.J. Conduction in segmentally demyelinated mammalian central axons. J. Neurosci., 1997, 17, 7267-7277.
-
(1997)
J. Neurosci
, vol.17
, pp. 7267-7277
-
-
Felts, P.A.1
Baker, T.A.2
Smith, K.J.3
-
82
-
-
0017902740
-
The internodal axon membrane: Electrical excitability and continuous conduction in segmental demyelination
-
Bostock, H., Sears, T.A. The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination. J. Physiol., 1978, 280, 273-301.
-
(1978)
J. Physiol
, vol.280
, pp. 273-301
-
-
Bostock, H.1
Sears, T.A.2
-
83
-
-
0026556810
-
Ionic mechanisms of anoxic injury in mammalian CNS white matter: Role of Na+ channels and Na(+)-Ca2+ exchanger
-
Stys, P.K., Waxman, S.G., Ransom, B.R. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. J. Neurosci., 1992, 12, 430-439.
-
(1992)
J. Neurosci
, vol.12
, pp. 430-439
-
-
Stys, P.K.1
Waxman, S.G.2
Ransom, B.R.3
-
84
-
-
64049119359
-
Multiple sclerosis therapeutics: Unexpected outcomes clouding undisputed successes
-
Wiendl, H., Hohlfeld, R. Multiple sclerosis therapeutics: unexpected outcomes clouding undisputed successes. Neurology, 2009, 72, 1008-1015.
-
(2009)
Neurology
, vol.72
, pp. 1008-1015
-
-
Wiendl, H.1
Hohlfeld, R.2
-
85
-
-
22444447949
-
Primary progressive multiple sclerosis: Current and future treatment options
-
Leary, S.M., Thompson, A.J. Primary progressive multiple sclerosis: current and future treatment options. CNS Drugs, 2005, 19, 369-376.
-
(2005)
CNS Drugs
, vol.19
, pp. 369-376
-
-
Leary, S.M.1
Thompson, A.J.2
-
86
-
-
33846833929
-
Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial
-
Wolinsky, J.S., Narayana, P.A., O'Connor, P., Coyle, P.K., Ford, C., Johnson, K., Miller, A., Pardo, L., Kadosh, S., Ladkani, D. Glatiramer acetate in primary progressive multiple sclerosis: results of a multinational, multicenter, double-blind, placebo-controlled trial. Ann.Neurol., 2007, 61, 14-24.
-
(2007)
Ann.Neurol
, vol.61
, pp. 14-24
-
-
Wolinsky, J.S.1
Narayana, P.A.2
O'Connor, P.3
Coyle, P.K.4
Ford, C.5
Johnson, K.6
Miller, A.7
Pardo, L.8
Kadosh, S.9
Ladkani, D.10
-
87
-
-
0037435526
-
Interferon beta-1a in primary progressive MS: An exploratory, randomized, controlled trial
-
Leary, S.M., Miller, D.H., Stevenson, V.L., Brex, P.A., Chard, D.T., Thompson, A.J. Interferon beta-1a in primary progressive MS: an exploratory, randomized, controlled trial. Neurology, 2003, 60, 44-51.
-
(2003)
Neurology
, vol.60
, pp. 44-51
-
-
Leary, S.M.1
Miller, D.H.2
Stevenson, V.L.3
Brex, P.A.4
Chard, D.T.5
Thompson, A.J.6
-
89
-
-
72449124379
-
A single-center, randomized, double-blind, placebo-controlled study of interferon beta-1b on primary progressive and transitional multiple sclerosis
-
Montalban, X., Sastre-Garriga, J., Tintore, M., Brieva, L., Aymerich, F.X., Rio, J., Porcel, J., Borras, C., Nos, C., Rovira, A. A single-center, randomized, double-blind, placebo-controlled study of interferon beta-1b on primary progressive and transitional multiple sclerosis. Mult. Scler., 2009, 15, 1195-1205.
-
(2009)
Mult. Scler
, vol.15
, pp. 1195-1205
-
-
Montalban, X.1
Sastre-Garriga, J.2
Tintore, M.3
Brieva, L.4
Aymerich, F.X.5
Rio, J.6
Porcel, J.7
Borras, C.8
Nos, C.9
Rovira, A.10
-
90
-
-
3042643912
-
Mitoxantrone as a potential therapy for primary progressive multiple sclerosis
-
Stuve, O., Kita, M., Pelletier, D., Fox, R.J., Stone, J., Goodkin, D.E., Zamvil, S.S. Mitoxantrone as a potential therapy for primary progressive multiple sclerosis. Mult. Scler., 2004, 10, S58-61.
-
(2004)
Mult. Scler
, vol.10
-
-
Stuve, O.1
Kita, M.2
Pelletier, D.3
Fox, R.J.4
Stone, J.5
Goodkin, D.E.6
Zamvil, S.S.7
-
91
-
-
54949143968
-
The CAMMS223 Trial Investigators Alemtuzumab vs. Interferon Beta-1a in Early Multiple Sclerosis 10.1056/NEJMoa0802670
-
The CAMMS223 Trial Investigators Alemtuzumab vs. Interferon Beta-1a in Early Multiple Sclerosis 10.1056/NEJMoa0802670. N. Engl. J. Med., 2008, 359, 1786-1801.
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 1786-1801
-
-
-
92
-
-
31544467633
-
The window of therapeutic opportunity in multiple sclerosis: Evidence from monoclonal antibody therapy
-
Coles, A.J., Cox, A., Le Page, E., Jones, J., Trip, S.A., Deans, J., Seaman, S., Miller, D.H., Hale, G., Waldmann, H., Compston, D.A. The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J. Neurol., 2006, 253, 98-108.
-
(2006)
J. Neurol
, vol.253
, pp. 98-108
-
-
Coles, A.J.1
Cox, A.2
Le Page, E.3
Jones, J.4
Trip, S.A.5
Deans, J.6
Seaman, S.7
Miller, D.H.8
Hale, G.9
Waldmann, H.10
Compston, D.A.11
-
93
-
-
0034646216
-
Cladribine and progressive MS: Clinical and MRI outcomes of a multicenter controlled trial. Cladribine MRI Study Group
-
Rice, G.P., Filippi, M., Comi, G. Cladribine and progressive MS: clinical and MRI outcomes of a multicenter controlled trial. Cladribine MRI Study Group. Neurology, 2000, 54, 1145-1155.
-
(2000)
Neurology
, vol.54
, pp. 1145-1155
-
-
Rice, G.P.1
Filippi, M.2
Comi, G.3
-
94
-
-
0035849496
-
Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results
-
Group S.S. Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results. Neurology, 2001, 56, 1496-1504.
-
(2001)
Neurology
, vol.56
, pp. 1496-1504
-
-
Group, S.S.1
-
95
-
-
0032494792
-
Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS
-
Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS. Lancet, 1998, 352, 1491-1497.
-
(1998)
Lancet
, vol.352
, pp. 1491-1497
-
-
-
96
-
-
8844285856
-
Interferon beta-1b in secondary progressive MS: A combined analysis of the two trials
-
Kappos, L., Weinshenker, B., Pozzilli, C., Thompson, A.J., Dahlke, F., Beckmann, K., Polman, C., McFarland, H. Interferon beta-1b in secondary progressive MS: a combined analysis of the two trials. Neurology, 2004, 63, 1779-1787.
-
(2004)
Neurology
, vol.63
, pp. 1779-1787
-
-
Kappos, L.1
Weinshenker, B.2
Pozzilli, C.3
Thompson, A.J.4
Dahlke, F.5
Beckmann, K.6
Polman, C.7
McFarland, H.8
-
97
-
-
0037153729
-
Mitoxantrone in progressive multiple sclerosis: A placebo-controlled, double-blind, randomised, multicentre trial
-
Hartung, H.P., Gonsette, R., Konig, N., Kwiecinski, H., Guseo, A., Morrissey, S.P., Krapf, H., Zwingers, T. Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial. Lancet, 2002, 360, 2018-2025.
-
(2002)
Lancet
, vol.360
, pp. 2018-2025
-
-
Hartung, H.P.1
Gonsette, R.2
Konig, N.3
Kwiecinski, H.4
Guseo, A.5
Morrissey, S.P.6
Krapf, H.7
Zwingers, T.8
-
98
-
-
4344594349
-
Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis
-
Debouverie, M., Vandenberghe, N., Morrissey, S.P., Anxionnat, R., Pittion-Vouyovitch, S., Vespignani, H., Edan, G. Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis. Mult. Scler., 2004, 10, 407-412.
-
(2004)
Mult. Scler
, vol.10
, pp. 407-412
-
-
Debouverie, M.1
Vandenberghe, N.2
Morrissey, S.P.3
Anxionnat, R.4
Pittion-Vouyovitch, S.5
Vespignani, H.6
Edan, G.7
-
99
-
-
39049142995
-
The HERMES Trial Group B-Cell Depletion with Rituximab in Relapsing-Remitting Multiple Sclerosis
-
Hauser, S.L., Waubant, E., Arnold, D.L., Vollmer, T., Antel, J., Fox, R.J., Bar-Or, A., Panzara, M., Sarkar, N., Agarwal, S., Langer-Gould, A., Smith, C.H., The HERMES Trial Group B-Cell Depletion with Rituximab in Relapsing-Remitting Multiple Sclerosis. N. Engl. J. Med., 2008, 358, 676-688.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 676-688
-
-
Hauser, S.L.1
Waubant, E.2
Arnold, D.L.3
Vollmer, T.4
Antel, J.5
Fox, R.J.6
Bar-Or, A.7
Panzara, M.8
Sarkar, N.9
Agarwal, S.10
Langer-Gould, A.11
Smith, C.H.12
-
100
-
-
13444274684
-
Effect of Rituximab on the Peripheral Blood and Cerebrospinal Fluid B Cells in Patients With Primary Progressive Multiple Sclerosis
-
Monson, N.L., Cravens, P.D., Frohman, E.M., Hawker, K., Racke, M.K. Effect of Rituximab on the Peripheral Blood and Cerebrospinal Fluid B Cells in Patients With Primary Progressive Multiple Sclerosis. Arch. Neurol., 2005, 62, 258-264.
-
(2005)
Arch. Neurol
, vol.62
, pp. 258-264
-
-
Monson, N.L.1
Cravens, P.D.2
Frohman, E.M.3
Hawker, K.4
Racke, M.K.5
-
101
-
-
16844366404
-
An open label study of the effects of rituximab in neuromyelitis optica
-
Cree, B.A.C., Lamb, S., Morgan, K., Chen, A., Waubant, E., Genain, C. An open label study of the effects of rituximab in neuromyelitis optica. Neurology, 2005, 64, 1270-1272.
-
(2005)
Neurology
, vol.64
, pp. 1270-1272
-
-
Cree, B.A.C.1
Lamb, S.2
Morgan, K.3
Chen, A.4
Waubant, E.5
Genain, C.6
-
102
-
-
0141593519
-
Hematopoietic stem cell transplantation for progressive multiple sclerosis: Failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
-
Burt, R.K., Cohen, B.A., Russell, E., Spero, K., Joshi, A., Oyama, Y., Karpus, W.J., Luo, K., Jovanovic, B., Traynor, A., Karlin, K., Stefoski, D., Burns, W.H. Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores. Blood, 2003, 102, 2373-2378.
-
(2003)
Blood
, vol.102
, pp. 2373-2378
-
-
Burt, R.K.1
Cohen, B.A.2
Russell, E.3
Spero, K.4
Joshi, A.5
Oyama, Y.6
Karpus, W.J.7
Luo, K.8
Jovanovic, B.9
Traynor, A.10
Karlin, K.11
Stefoski, D.12
Burns, W.H.13
-
103
-
-
33646819993
-
Sphingosine Kinase and Sphingosine-1-Phosphate Regulate Migration, Endocytosis and Apoptosis of Dendritic Cells
-
Eigenbrod, S., Derwand, R., Jakl, V., Endres, S., Eigler, A. Sphingosine Kinase and Sphingosine-1-Phosphate Regulate Migration, Endocytosis and Apoptosis of Dendritic Cells. Immunol. Investig., 2006, 35, 149-165.
-
(2006)
Immunol. Investig
, vol.35
, pp. 149-165
-
-
Eigenbrod, S.1
Derwand, R.2
Jakl, V.3
Endres, S.4
Eigler, A.5
-
104
-
-
17644365138
-
Chemokines, Sphingosine-1-Phosphate, and cell migration in secondary lymphoid organs
-
Cyster, J.G. Chemokines, Sphingosine-1-Phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol., 2005, 23, 127-159.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 127-159
-
-
Cyster, J.G.1
-
105
-
-
34547497820
-
Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: A 3-year follow-up analysis of the BENEFIT study
-
Kappos, L., Freedman, M.S., Polman, C.H., Edan, G., Hartung, H.-P., Miller, D.H., Montalbán, X., Barkhof, F., Radü, E.-W., Bauer, L., Dahms, S., Lanius, V., Pohl, C., Sandbrink, R. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study. Lancet, 2007, 370, 389-397.
-
(2007)
Lancet
, vol.370
, pp. 389-397
-
-
Kappos, L.1
Freedman, M.S.2
Polman, C.H.3
Edan, G.4
Hartung, H.-P.5
Miller, D.H.6
Montalbán, X.7
Barkhof, F.8
Radü, E.-W.9
Bauer, L.10
Dahms, S.11
Lanius, V.12
Pohl, C.13
Sandbrink, R.14
-
106
-
-
34247608145
-
New natural history of interferon-beta-treated relapsing multiple sclerosis
-
Trojano, M., Pellegrini, F., Fuiani, A., Paolicelli, D., Zipoli, V., Zimatore, G.B., Di Monte, E., Portaccio, E., Lepore, V., Livrea, P., Amato, M.P. New natural history of interferon-beta-treated relapsing multiple sclerosis. Ann. Neurol., 2007, 61, 300-306.
-
(2007)
Ann. Neurol
, vol.61
, pp. 300-306
-
-
Trojano, M.1
Pellegrini, F.2
Fuiani, A.3
Paolicelli, D.4
Zipoli, V.5
Zimatore, G.B.6
Di Monte, E.7
Portaccio, E.8
Lepore, V.9
Livrea, P.10
Amato, M.P.11
-
107
-
-
1842845857
-
The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study
-
Kalkers, N.F., Barkhof, F., Bergers, E., van Schijndel, R., Polman, C.H. The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: a pilot study. Mult. Scler., 2002, 8, 532-533.
-
(2002)
Mult. Scler
, vol.8
, pp. 532-533
-
-
Kalkers, N.F.1
Barkhof, F.2
Bergers, E.3
van Schijndel, R.4
Polman, C.H.5
-
108
-
-
0032442475
-
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
-
Yrjanheikki, J., Keinanen, R., Pellikka, M., Hokfelt, T., Koistinaho, J. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc. Natl. Acad. Sci. USA, 1998, 95, 15769-15774.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15769-15774
-
-
Yrjanheikki, J.1
Keinanen, R.2
Pellikka, M.3
Hokfelt, T.4
Koistinaho, J.5
-
109
-
-
10344257516
-
Additive effect of the combination of glatiramer acetate and minocycline in a model of MS
-
Giuliani, F., Metz, L.M., Wilson, T., Fan, Y., Bar-Or, A., Wee Yong, V. Additive effect of the combination of glatiramer acetate and minocycline in a model of MS. J. Neuroimmunol., 2005, 158, 213-221.
-
(2005)
J. Neuroimmunol
, vol.158
, pp. 213-221
-
-
Giuliani, F.1
Metz, L.M.2
Wilson, T.3
Fan, Y.4
Bar-Or, A.5
Wee Yong, V.6
-
110
-
-
41849124231
-
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis
-
Basso, A.S., Frenkel, D., Quintana, F.J., Costa-Pinto, F.A., Petrovic-Stojkovic, S., Puckett, L., Monsonego, A., Bar-Shir, A., Engel, Y., Gozin, M., Weiner, H.L. Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. J. Clin. Invest., 2008, 118, 1532-1543.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 1532-1543
-
-
Basso, A.S.1
Frenkel, D.2
Quintana, F.J.3
Costa-Pinto, F.A.4
Petrovic-Stojkovic, S.5
Puckett, L.6
Monsonego, A.7
Bar-Shir, A.8
Engel, Y.9
Gozin, M.10
Weiner, H.L.11
-
111
-
-
0037191415
-
Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis
-
Lo, A.C., Black, J.A., Waxman, S.G. Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. Neuroreport, 2002, 13, 1909-1912.
-
(2002)
Neuroreport
, vol.13
, pp. 1909-1912
-
-
Lo, A.C.1
Black, J.A.2
Waxman, S.G.3
-
112
-
-
2142760098
-
Axonal protection using flecainide in experimental autoimmune encephalomyelitis
-
Bechtold, D.A., Kapoor, R., Smith, K.J. Axonal protection using flecainide in experimental autoimmune encephalomyelitis. Ann. Neurol., 2004, 55, 607-616.
-
(2004)
Ann. Neurol
, vol.55
, pp. 607-616
-
-
Bechtold, D.A.1
Kapoor, R.2
Smith, K.J.3
-
113
-
-
36849009834
-
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system
-
Friese, M.A., Craner, M.J., Etzensperger, R., Vergo, S., Wemmie, J.A., Welsh, M.J., Vincent, A., Fugger, L. Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat. Med., 2007, 13, 1483-1489.
-
(2007)
Nat. Med
, vol.13
, pp. 1483-1489
-
-
Friese, M.A.1
Craner, M.J.2
Etzensperger, R.3
Vergo, S.4
Wemmie, J.A.5
Welsh, M.J.6
Vincent, A.7
Fugger, L.8
-
114
-
-
33748908067
-
Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models
-
Kaneko, S., Wang, J., Kaneko, M., Yiu, G., Hurrell, J.M., Chitnis, T., Khoury, S.J., He, Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J. Neurosci., 2006, 26, 9794-9804.
-
(2006)
J. Neurosci
, vol.26
, pp. 9794-9804
-
-
Kaneko, S.1
Wang, J.2
Kaneko, M.3
Yiu, G.4
Hurrell, J.M.5
Chitnis, T.6
Khoury, S.J.7
He, Z.8
-
115
-
-
0037064261
-
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
-
Agnello, D., Bigini, P., Villa, P., Mennini, T., Cerami, A., Brines, M.L., Ghezzi, P. Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res., 2002, 952, 128-134.
-
(2002)
Brain Res
, vol.952
, pp. 128-134
-
-
Agnello, D.1
Bigini, P.2
Villa, P.3
Mennini, T.4
Cerami, A.5
Brines, M.L.6
Ghezzi, P.7
-
116
-
-
12744273391
-
Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis
-
Sattler, M.B., Merkler, D., Maier, K., Stadelmann, C., Ehrenreich, H., Bahr, M., Diem, R. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell Death Differ., 2004, 11(Suppl 2), S181-192.
-
(2004)
Cell Death Differ
, vol.11
, Issue.SUPPL. 2
-
-
Sattler, M.B.1
Merkler, D.2
Maier, K.3
Stadelmann, C.4
Ehrenreich, H.5
Bahr, M.6
Diem, R.7
-
117
-
-
34848841517
-
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis
-
Ehrenreich, H., Fischer, B., Norra, C., Schellenberger, F., Stender, N., Stiefel, M., Siren, A.L., Paulus, W., Nave, K.A., Gold, R., Bartels, C. Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain, 2007, 130, 2577-2588.
-
(2007)
Brain
, vol.130
, pp. 2577-2588
-
-
Ehrenreich, H.1
Fischer, B.2
Norra, C.3
Schellenberger, F.4
Stender, N.5
Stiefel, M.6
Siren, A.L.7
Paulus, W.8
Nave, K.A.9
Gold, R.10
Bartels, C.11
-
118
-
-
0037122960
-
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
-
Chang, A., Tourtellotte, W.W., Rudick, R., Trapp, B.D. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N. Engl. J. Med., 2002, 346, 165-173.
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 165-173
-
-
Chang, A.1
Tourtellotte, W.W.2
Rudick, R.3
Trapp, B.D.4
-
119
-
-
46849098585
-
Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
-
Kuhlmann, T., Miron, V., Cuo, Q., Wegner, C., Antel, J., Bruck, W. Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 2008, 131, 1749-1758.
-
(2008)
Brain
, vol.131
, pp. 1749-1758
-
-
Kuhlmann, T.1
Miron, V.2
Cuo, Q.3
Wegner, C.4
Antel, J.5
Bruck, W.6
-
120
-
-
39849101009
-
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
-
Han, M.H., Hwang, S.I., Roy, D.B., Lundgren, D.H., Price, J.V., Ousman, S.S., Fernald, G.H., Gerlitz, B., Robinson, W.H., Baranzini, S.E., Grinnell, B.W., Raine, C.S., Sobel, R.A., Han, D.K., Steinman, L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature, 2008, 451, 1076-1081.
-
(2008)
Nature
, vol.451
, pp. 1076-1081
-
-
Han, M.H.1
Hwang, S.I.2
Roy, D.B.3
Lundgren, D.H.4
Price, J.V.5
Ousman, S.S.6
Fernald, G.H.7
Gerlitz, B.8
Robinson, W.H.9
Baranzini, S.E.10
Grinnell, B.W.11
Raine, C.S.12
Sobel, R.A.13
Han, D.K.14
Steinman, L.15
-
121
-
-
22844453047
-
LINGO-1 negatively regulates myelination by oligodendrocytes
-
Mi, S., Miller, R.H., Lee, X., Scott, M.L., Shulag-Morskaya, S., Shao, Z., Chang, J., Thill, G., Levesque, M., Zhang, M., Hession, C., Sah, D., Trapp, B., He, Z., Jung, V., McCoy, J.M., Pepinsky, R.B. LINGO-1 negatively regulates myelination by oligodendrocytes. Nat. Neurosci., 2005,8, 745-751.
-
(2005)
Nat. Neurosci
, vol.8
, pp. 745-751
-
-
Mi, S.1
Miller, R.H.2
Lee, X.3
Scott, M.L.4
Shulag-Morskaya, S.5
Shao, Z.6
Chang, J.7
Thill, G.8
Levesque, M.9
Zhang, M.10
Hession, C.11
Sah, D.12
Trapp, B.13
He, Z.14
Jung, V.15
McCoy, J.M.16
Pepinsky, R.B.17
-
122
-
-
65249142739
-
Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
-
Mi, S., Miller, R.H., Tang, W., Lee, X., Hu, B., Wu, W., Zhang, Y., Shields, C.B., Miklasz, S., Shea, D., Mason, J., Franklin, R.J., Ji, B., Shao, Z., Chedotal, A., Bernard, F., Roulois, A., Xu, J., Jung, V., Pepinsky, B. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Ann. Neurol., 2009, 65, 304-315.
-
(2009)
Ann. Neurol
, vol.65
, pp. 304-315
-
-
Mi, S.1
Miller, R.H.2
Tang, W.3
Lee, X.4
Hu, B.5
Wu, W.6
Zhang, Y.7
Shields, C.B.8
Miklasz, S.9
Shea, D.10
Mason, J.11
Franklin, R.J.12
Ji, B.13
Shao, Z.14
Chedotal, A.15
Bernard, F.16
Roulois, A.17
Xu, J.18
Jung, V.19
Pepinsky, B.20
more..
-
123
-
-
70449418132
-
Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial
-
Hawker, K., O'Connor, P., Freedman, M.S., Calabresi, P.A., Antel, J., Simon, J., Hauser, S., Waubant, E., Vollmer, T., Panitch, H., Zhang, J., Chin, P., Smith, C.H. Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial. Ann. Neurol., 2009, 66, 460-471.
-
(2009)
Ann. Neurol
, vol.66
, pp. 460-471
-
-
Hawker, K.1
O'Connor, P.2
Freedman, M.S.3
Calabresi, P.A.4
Antel, J.5
Simon, J.6
Hauser, S.7
Waubant, E.8
Vollmer, T.9
Panitch, H.10
Zhang, J.11
Chin, P.12
Smith, C.H.13
-
124
-
-
0037441441
-
Interferon beta-1a in primary progressive multiple sclerosis
-
Leary, S.M., Thompson, A.J. Interferon beta-1a in primary progressive multiple sclerosis. J. Neurol. Sci., 2003, 206, 215-216.
-
(2003)
J. Neurol. Sci
, vol.206
, pp. 215-216
-
-
Leary, S.M.1
Thompson, A.J.2
-
125
-
-
63749125437
-
Autologous attenuated T-cell vaccine (Tovaxin) dose escalation in multiple sclerosis relapsing-remitting and secondary progressive patients nonresponsive to approved immunomodulatory therapies
-
Loftus, B., Newsom, B., Montgomery, M., Von Gynz-Rekowski, K., Riser, M., Inman, S., Garces, P., Rill, D., Zhang, J., Williams, J.C. Autologous attenuated T-cell vaccine (Tovaxin) dose escalation in multiple sclerosis relapsing-remitting and secondary progressive patients nonresponsive to approved immunomodulatory therapies. Clin. Immunol., 2009, 131, 202-215.
-
(2009)
Clin. Immunol
, vol.131
, pp. 202-215
-
-
Loftus, B.1
Newsom, B.2
Montgomery, M.3
Von Gynz-Rekowski, K.4
Riser, M.5
Inman, S.6
Garces, P.7
Rill, D.8
Zhang, J.9
Williams, J.C.10
-
126
-
-
39549098027
-
Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: A randomized placebo controlled multicentre study
-
Pohlau, D., Przuntek, H., Sailer, M., Bethke, F., Koehler, J., Konig, N., Heesen, C., Spath, P., Andresen, I. Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre study. Mult. Scler., 2007, 13, 1107-1117.
-
(2007)
Mult. Scler
, vol.13
, pp. 1107-1117
-
-
Pohlau, D.1
Przuntek, H.2
Sailer, M.3
Bethke, F.4
Koehler, J.5
Konig, N.6
Heesen, C.7
Spath, P.8
Andresen, I.9
-
127
-
-
60649090430
-
Sustained-release oral fampridine in multiple sclerosis: A randomised, double-blind, controlled trial
-
Goodman, A.D., Brown, T.R., Krupp, L.B., Schapiro, R.T., Schwid, S.R., Cohen, R., Marinucci, L.N., Blight, A.R. Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial. Lancet, 2009, 373, 732-738.
-
(2009)
Lancet
, vol.373
, pp. 732-738
-
-
Goodman, A.D.1
Brown, T.R.2
Krupp, L.B.3
Schapiro, R.T.4
Schwid, S.R.5
Cohen, R.6
Marinucci, L.N.7
Blight, A.R.8
-
128
-
-
34547655745
-
Treatment of active secondary progressive multiple sclerosis with treosulfan
-
Wiendl, H., Kieseier, B.C., Weissert, R., Mylius, H.A., Pichlmeier, U., Hartung, H.P., Melms, A., Kuker, W., Weller, M. Treatment of active secondary progressive multiple sclerosis with treosulfan. J. Neurol., 2007, 254, 884-889.
-
(2007)
J. Neurol
, vol.254
, pp. 884-889
-
-
Wiendl, H.1
Kieseier, B.C.2
Weissert, R.3
Mylius, H.A.4
Pichlmeier, U.5
Hartung, H.P.6
Melms, A.7
Kuker, W.8
Weller, M.9
|