Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II

Journal of Biological Chemistry

Volumn 285, Issue 48, 2010, Pages 37641-37649

  Durrington, Hannah J ^a,b   Upton, Paul D ^a   Hoer, Simon ^b   Boname, Jessica ^b   Dunmore, Benjamin J ^a   Yang, Jun ^a   Crilley, Trina K ^a   Butler, Lynn M ^c   Blackbourn, David J ^c   Nash, Gerard B ^c   Lehner, Paul J ^b   Morrell, Nicholas W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL SURFACE RECEPTORS; CELL SURFACES; CYTOPLASMIC DOMAINS; DOWN-REGULATION; E3 LIGASE; ECTOPIC EXPRESSIONS; ETIOLOGIC AGENTS; KAPOSI SARCOMA-ASSOCIATED HERPESVIRUS; LYSOSOMAL DEGRADATION; PATHOBIOLOGY; PULMONARY ARTERIAL HYPERTENSION; TUMORIGENESIS; TYPE II; UBIQUITIN; UBIQUITINATION; VASCULAR CELLS; VASCULAR DISEASE;

AMINO ACIDS; BONE; CELL MEMBRANES; DEGRADATION; GENE EXPRESSION; HYDROGELS; MAMMALS; SIGNALING; TUMORS;

PROTEINS;

ATROPHIN 1 INTERACTING PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; INTERCELLULAR ADHESION MOLECULE 1; LYSINE; PROTEIN ITCH; PROTEIN K5; SMAD1 PROTEIN; SMAD5 PROTEIN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; HERPES VIRUS INFECTION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; HUMAN TISSUE; IMMUNOBLOTTING; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RING FINGER MOTIF; SIGNAL TRANSDUCTION; UBIQUITINATION;

BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELLS, CULTURED; ENDOTHELIAL CELLS; HELA CELLS; HERPESVIRUS 8, HUMAN; HUMANS; LYSOSOMES; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SARCOMA, KAPOSI; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRAL PROTEINS;

HUMAN HERPESVIRUS 8; MAMMALIA;

EID: 78549286371     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.132415     Document Type: Article

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