Teratogen-induced oxidative stress targets glyceraldehyde-3-phosphate dehydrogenase in the organogenesis stage mouse embryo

Toxicological Sciences

Volumn 118, Issue 2, 2010, Pages 686-695

  Schlisser, Ava E ^a   Yan, Jin ^a,b   Hales, Barbara F ^a  

^a MCGILL UNIVERSITY   (Canada)

^b TOXICOLOGY RESEARCH DIVISION   (Canada)

Author keywords

4 hydroxy 2 nonenal; Glyceraldehyde 3 phosphate dehydrogenase; Glycolysis; Nuclear translocation; Oxidative stress; Protein adducts

Indexed keywords

4 HYDROXYNONENAL; ALDOLASE 1; ASPARTATE AMINOTRANSFERASE ISOENZYME 2; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; E1A ASSOCIATED P300 PROTEIN; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROXYUREA; LACTIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA REPAIR; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOTOXICITY; ENERGY METABOLISM; ENZYME ACTIVITY; FEMALE; GENE TRANSLOCATION; NONHUMAN; ORGANOGENESIS; OXIDATIVE STRESS;

ABNORMALITIES, DRUG-INDUCED; ALDEHYDES; ANIMALS; ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL; CELL NUCLEUS; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FRUCTOSE-BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HYDROXYUREA; MICE; ORGANOGENESIS; OXIDATIVE STRESS; TERATOGENS; TRANSLOCATION, GENETIC;

MUS;

EID: 78549238911     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq287     Document Type: Article

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