메뉴 건너뛰기




Volumn 4, Issue 2, 2008, Pages 109-115

Wnt signaling in limb organogenesis

Author keywords

Limb initiation; Morphogenesis; Outgrowth; Patterning; Wnts

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; WNT PROTEIN; WNT11 PROTEIN; WNT4 PROTEIN; WNT5A PROTEIN; WNT5B PROTEIN;

EID: 45849144382     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.4.2.5857     Document Type: Review
Times cited : (52)

References (98)
  • 1
    • 0015012597 scopus 로고    scopus 로고
    • Searls RL and Janners MY The initiation of limb bud outgrowth in the embryonic chick. Dev Biol 1971; 24:198-213.
    • Searls RL and Janners MY The initiation of limb bud outgrowth in the embryonic chick. Dev Biol 1971; 24:198-213.
  • 2
    • 0017625085 scopus 로고
    • Limb-somite relationship: Origin of the limb musculature
    • Chevallier A, Kieny M, and Mauger A Limb-somite relationship: origin of the limb musculature. J Embryol Exp Morphol 1977; 41:245-58.
    • (1977) J Embryol Exp Morphol , vol.41 , pp. 245-258
    • Chevallier, A.1    Kieny, M.2    Mauger, A.3
  • 3
    • 0016326266 scopus 로고
    • Origin of wing musculature. Experimental studies on quail and chick embryos]
    • Christ B, Jacob HJ, and Jacob M [Origin of wing musculature. Experimental studies on quail and chick embryos]. Experientia 1974; 30:1446-9.
    • (1974) Experientia , vol.30 , pp. 1446-1449
    • Christ, B.1    Jacob, H.J.2    Jacob, M.3
  • 4
    • 0017598019 scopus 로고
    • Experimental analysis of the origin of the wing musculature in avian embryos
    • Christ B, Jacob HJ, and Jacob M Experimental analysis of the origin of the wing musculature in avian embryos. Anat Embryol (Berl) 1977; 150:171-86.
    • (1977) Anat Embryol (Berl) , vol.150 , pp. 171-186
    • Christ, B.1    Jacob, H.J.2    Jacob, M.3
  • 5
    • 0020118107 scopus 로고    scopus 로고
    • Rowe DA and Fallon JF The proximodistal determination of skeletal parts in the developing chick leg. J Embryol Exp Morphol 1982; 68:1-7
    • Rowe DA and Fallon JF The proximodistal determination of skeletal parts in the developing chick leg. J Embryol Exp Morphol 1982; 68:1-7.
  • 6
    • 0016283408 scopus 로고    scopus 로고
    • Summerbell D Interaction between the proximo-distal and antero-posterior co-ordinates of positional value during the specification of positional information in the early development of the chick limb-bud. J Embryol Exp Morphol 1974; 32:227-37
    • Summerbell D Interaction between the proximo-distal and antero-posterior co-ordinates of positional value during the specification of positional information in the early development of the chick limb-bud. J Embryol Exp Morphol 1974; 32:227-37.
  • 7
    • 0036433866 scopus 로고    scopus 로고
    • Niswander L Interplay between the molecular signals that control vertebrate limb development
    • Niswander L Interplay between the molecular signals that control vertebrate limb development. Int J Dev Biol 2002; 46:877-81.
    • (2002) Int J Dev Biol , vol.46 , pp. 877-881
  • 8
    • 0037389087 scopus 로고    scopus 로고
    • Tickle C Patterning systems - from one end of the limb to the other. Dev Cell 2003; 4:449-58.
    • Tickle C Patterning systems - from one end of the limb to the other. Dev Cell 2003; 4:449-58.
  • 10
    • 0038011840 scopus 로고    scopus 로고
    • Mariani FV and Martin GR Deciphering skeletal patterning: clues from the limb. Nature 2003; 423:319-25.
    • Mariani FV and Martin GR Deciphering skeletal patterning: clues from the limb. Nature 2003; 423:319-25.
  • 11
    • 0036860704 scopus 로고    scopus 로고
    • Huelsken J and Behrens J The Wnt signalling pathway. J Cell Sci 2002; 115:3977-8.
    • Huelsken J and Behrens J The Wnt signalling pathway. J Cell Sci 2002; 115:3977-8.
  • 12
    • 0035479835 scopus 로고    scopus 로고
    • Huelsken J and Birchmeier W New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev 2001; 11:547-53.
    • Huelsken J and Birchmeier W New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev 2001; 11:547-53.
  • 13
    • 19644373254 scopus 로고    scopus 로고
    • Nusse R Wnt signaling in disease and in development
    • Nusse R Wnt signaling in disease and in development. Cell Res 2005; 15:28-32.
    • (2005) Cell Res , vol.15 , pp. 28-32
  • 14
    • 0034053069 scopus 로고    scopus 로고
    • Peifer M and Polakis P Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 2000; 287:1606-9.
    • Peifer M and Polakis P Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 2000; 287:1606-9.
  • 15
    • 0032406715 scopus 로고    scopus 로고
    • Wodarz A and Nusse R Mechanisms of Wnt signaling in development
    • Wodarz A and Nusse R Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998; 14:59-88.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
  • 16
    • 33746037296 scopus 로고    scopus 로고
    • PCP signaling: A veritable polar star in establishing patterns of polarity in embryonic tissues
    • Barrow JR Wnt/PCP signaling: a veritable polar star in establishing patterns of polarity in embryonic tissues. Semin Cell Dev Biol 2006; 17:185-93.
    • (2006) Semin Cell Dev Biol , vol.17 , pp. 185-193
    • Wnt, B.J.R.1
  • 17
    • 0034214847 scopus 로고    scopus 로고
    • The Wnt/Ca2+ pathway: A new vertebrate Wnt signaling pathway takes shape
    • Kuhl M, Sheldahl LC, Park M, Miller JR, and Moon RT The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet 2000; 16:279-83.
    • (2000) Trends Genet , vol.16 , pp. 279-283
    • Kuhl, M.1    Sheldahl, L.C.2    Park, M.3    Miller, J.R.4    Moon, R.T.5
  • 18
    • 8444251784 scopus 로고    scopus 로고
    • Logan CY and Nusse R The Wnt signaling pathway in development and disease
    • Logan CY and Nusse R The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20:781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
  • 19
    • 0032941717 scopus 로고    scopus 로고
    • Eastman Q and Grosschedl R Regulation of LEF-1/TCF transcription factors by Wnt and other signals. Curr Opin Cell Biol 1999; 11:233-40.
    • Eastman Q and Grosschedl R Regulation of LEF-1/TCF transcription factors by Wnt and other signals. Curr Opin Cell Biol 1999; 11:233-40.
  • 21
    • 0032898364 scopus 로고    scopus 로고
    • Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells
    • Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, and Wu D Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem 1999; 274:129-34.
    • (1999) J Biol Chem , vol.274 , pp. 129-134
    • Li, L.1    Yuan, H.2    Xie, W.3    Mao, J.4    Caruso, A.M.5    McMahon, A.6    Sussman, D.J.7    Wu, D.8
  • 22
    • 0033166245 scopus 로고    scopus 로고
    • Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner
    • Sheldahl LC, Park M, Malbon CC, and Moon RT Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner. Curr Biol 1999; 9:695-8.
    • (1999) Curr Biol , vol.9 , pp. 695-698
    • Sheldahl, L.C.1    Park, M.2    Malbon, C.C.3    Moon, R.T.4
  • 24
    • 0037118064 scopus 로고    scopus 로고
    • The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos
    • Saneyoshi T, Kume S, Amasaki Y, and Mikoshiba K The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos. Nature 2002; 417:295-9.
    • (2002) Nature , vol.417 , pp. 295-299
    • Saneyoshi, T.1    Kume, S.2    Amasaki, Y.3    Mikoshiba, K.4
  • 26
    • 0041971124 scopus 로고    scopus 로고
    • Naiche LA and Papaioannou VE Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois
    • Naiche LA and Papaioannou VE Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development 2003; 130:2681-93.
    • (2003) Development , vol.130 , pp. 2681-2693
  • 27
  • 31
    • 33646130168 scopus 로고    scopus 로고
    • Multiple roles of mesenchymal beta-catenin during murine limb patterning
    • Hill TP, Taketo MM, Birchmeier W, and Hartmann C Multiple roles of mesenchymal beta-catenin during murine limb patterning. Development 2006; 133:1219-29.
    • (2006) Development , vol.133 , pp. 1219-1229
    • Hill, T.P.1    Taketo, M.M.2    Birchmeier, W.3    Hartmann, C.4
  • 33
    • 0031569359 scopus 로고    scopus 로고
    • Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse
    • Yoshikawa Y, Fujimori T, McMahon AP, and Takada S Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Dev Biol 1997; 183:234-42.
    • (1997) Dev Biol , vol.183 , pp. 234-242
    • Yoshikawa, Y.1    Fujimori, T.2    McMahon, A.P.3    Takada, S.4
  • 34
    • 0344820773 scopus 로고    scopus 로고
    • Wnt3a-/ - like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice
    • Galceran J, Farinas I, Depew MJ, Clevers H, and Grosschedl R Wnt3a-/ - like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev 1999; 13:709-17.
    • (1999) Genes Dev , vol.13 , pp. 709-717
    • Galceran, J.1    Farinas, I.2    Depew, M.J.3    Clevers, H.4    Grosschedl, R.5
  • 35
    • 0037314332 scopus 로고    scopus 로고
    • Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge
    • Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, and McMahon AP Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev 2003; 17:394-409.
    • (2003) Genes Dev , vol.17 , pp. 394-409
    • Barrow, J.R.1    Thomas, K.R.2    Boussadia-Zahui, O.3    Moore, R.4    Kemler, R.5    Capecchi, M.R.6    McMahon, A.P.7
  • 36
    • 0032938813 scopus 로고    scopus 로고
    • Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
    • Yamaguchi TP, Bradley A, McMahon AP, and Jones S A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 1999; 126:1211-23.
    • (1999) Development , vol.126 , pp. 1211-1223
    • Yamaguchi, T.P.1    Bradley, A.2    McMahon, A.P.3    Jones, S.A.4
  • 37
    • 0027441061 scopus 로고
    • Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes
    • Dealy CN, Roth A, Ferrari D, Brown AM, and Kosher RA Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech Dev 1993; 43:175-86.
    • (1993) Mech Dev , vol.43 , pp. 175-186
    • Dealy, C.N.1    Roth, A.2    Ferrari, D.3    Brown, A.M.4    Kosher, R.A.5
  • 38
    • 0027201903 scopus 로고
    • Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds
    • Parr BA, Shea MJ, Vassileva G, and McMahon AP Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 1993; 119:247-61.
    • (1993) Development , vol.119 , pp. 247-261
    • Parr, B.A.1    Shea, M.J.2    Vassileva, G.3    McMahon, A.P.4
  • 39
    • 0030941498 scopus 로고    scopus 로고
    • A member of the Frizzled protein family mediating axis induction by Wnt-5A
    • He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, and Varmus H A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 1997; 275:1652-4.
    • (1997) Science , vol.275 , pp. 1652-1654
    • He, X.1    Saint-Jeannet, J.P.2    Wang, Y.3    Nathans, J.4    Dawid, I.5    Varmus, H.6
  • 40
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
    • Slusarski DC, Corces VG, and Moon RT Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 1997; 390:410-3.
    • (1997) Nature , vol.390 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.G.2    Moon, R.T.3
  • 41
    • 85177011364 scopus 로고    scopus 로고
    • Crossley PH and Martin GR The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 1995; 121:439-51.
    • Crossley PH and Martin GR The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 1995; 121:439-51.
  • 44
    • 0030982018 scopus 로고    scopus 로고
    • The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure
    • Michaud JL, Lapointe F, and Le Douarin NM The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure. Development 1997; 124:1453-63.
    • (1997) Development , vol.124 , pp. 1453-1463
    • Michaud, J.L.1    Lapointe, F.2    Le Douarin, N.M.3
  • 46
    • 0028951117 scopus 로고    scopus 로고
    • Parr BA and McMahon AP Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 1995; 374:350-3.
    • Parr BA and McMahon AP Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 1995; 374:350-3.
  • 47
    • 0028848301 scopus 로고
    • Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb
    • Riddle RD, Ensini M, Nelson C, Tsuchida T, Jessell TM, and Tabin C Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 1995; 83:631-40.
    • (1995) Cell , vol.83 , pp. 631-640
    • Riddle, R.D.1    Ensini, M.2    Nelson, C.3    Tsuchida, T.4    Jessell, T.M.5    Tabin, C.6
  • 48
    • 0029563650 scopus 로고
    • Dorsal cell fate specified by chick Lmx1 during vertebrate limb development
    • Vogel A, Rodriguez C, Warnken W, and Izpisua Belmonte JC Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 1995; 378:716-20.
    • (1995) Nature , vol.378 , pp. 716-720
    • Vogel, A.1    Rodriguez, C.2    Warnken, W.3    Izpisua Belmonte, J.C.4
  • 49
    • 0030855266 scopus 로고    scopus 로고
    • The role of Engrailed in establishing the dorsoventral axis of the chick limb
    • Logan C, Hornbruch A, Campbell I, and Lumsden A The role of Engrailed in establishing the dorsoventral axis of the chick limb. Development 1997; 124:2317-24.
    • (1997) Development , vol.124 , pp. 2317-2324
    • Logan, C.1    Hornbruch, A.2    Campbell, I.3    Lumsden, A.4
  • 50
    • 0028569704 scopus 로고
    • Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
    • Laufer E, Nelson CE, Johnson RL, Morgan BA, and Tabin C Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 1994; 79:993-1003.
    • (1994) Cell , vol.79 , pp. 993-1003
    • Laufer, E.1    Nelson, C.E.2    Johnson, R.L.3    Morgan, B.A.4    Tabin, C.5
  • 51
    • 0028149891 scopus 로고
    • A positive feedback loop coordinates growth and patterning in the vertebrate limb
    • Niswander L, Jeffrey S, Martin GR, and Tickle C A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 1994; 371:609-12.
    • (1994) Nature , vol.371 , pp. 609-612
    • Niswander, L.1    Jeffrey, S.2    Martin, G.R.3    Tickle, C.4
  • 52
    • 0028930947 scopus 로고
    • dorsal signals regulate anteroposterior patterning
    • Yang Y and Niswander L Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development
    • Yang Y and Niswander L Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 1995; 80:939-47.
    • (1995) Cell , vol.80 , pp. 939-947
  • 53
    • 0041030051 scopus 로고    scopus 로고
    • Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    • Zuniga A, Haramis AP, McMahon AP, and Zeller R Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature 1999; 401:598-602.
    • (1999) Nature , vol.401 , pp. 598-602
    • Zuniga, A.1    Haramis, A.P.2    McMahon, A.P.3    Zeller, R.4
  • 57
    • 3042702989 scopus 로고    scopus 로고
    • Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, and Meisler MH En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol 2004; 272:134-44.
    • Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, and Meisler MH En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol 2004; 272:134-44.
  • 58
    • 19544385099 scopus 로고    scopus 로고
    • Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb
    • Adamska M, Billi AC, Cheek S, and Meisler MH Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb. Dev Dyn 2005; 233:368-72.
    • (2005) Dev Dyn , vol.233 , pp. 368-372
    • Adamska, M.1    Billi, A.C.2    Cheek, S.3    Meisler, M.H.4
  • 59
    • 0034727078 scopus 로고    scopus 로고
    • An LDL-receptor-related protein mediates Wnt signalling in mice
    • Pinson KI, Brennan J, Monkley S, Avery BJ, and Skarnes WC An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 2000; 407:535-8.
    • (2000) Nature , vol.407 , pp. 535-538
    • Pinson, K.I.1    Brennan, J.2    Monkley, S.3    Avery, B.J.4    Skarnes, W.C.5
  • 62
    • 34247607671 scopus 로고    scopus 로고
    • Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway
    • Knobloch J, Shaughnessy JD, Jr., and Ruther U Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway. Faseb J 2007; 21:1410-21.
    • (2007) Faseb J , vol.21 , pp. 1410-1421
    • Knobloch, J.1    Shaughnessy Jr., J.D.2    Ruther, U.3
  • 64
    • 0042161921 scopus 로고    scopus 로고
    • Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb
    • Soshnikova N, Zechner D, Huelsken J, Mishina Y, Behringer RR, Taketo MM, Crenshaw EB, 3rd, and Birchmeier W Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev 2003; 17:1963-8.
    • (2003) Genes Dev , vol.17 , pp. 1963-1968
    • Soshnikova, N.1    Zechner, D.2    Huelsken, J.3    Mishina, Y.4    Behringer, R.R.5    Taketo, M.M.6    Crenshaw 3rd, E.B.7    Birchmeier, W.8
  • 66
    • 0028875718 scopus 로고
    • Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite
    • Munsterberg AE, Kitajewski J, Bumcrot DA, McMahon AP, and Lassar AB Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev 1995; 9:2911-22.
    • (1995) Genes Dev , vol.9 , pp. 2911-2922
    • Munsterberg, A.E.1    Kitajewski, J.2    Bumcrot, D.A.3    McMahon, A.P.4    Lassar, A.B.5
  • 70
    • 0037013294 scopus 로고    scopus 로고
    • Petropoulos H and Skerjanc IS Beta-catenin is essential and sufficient for skeletal myogenesis in P19 cells. J Biol Chem 2002; 277:15393-9
    • Petropoulos H and Skerjanc IS Beta-catenin is essential and sufficient for skeletal myogenesis in P19 cells. J Biol Chem 2002; 277:15393-9.
  • 73
    • 35748978870 scopus 로고    scopus 로고
    • A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells
    • Miller KA, Barrow J, Collinson JM, Davidson S, Lear M, Hill RE, and Mackenzie A A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells. Dev Biol 2007; 311:665-78.
    • (2007) Dev Biol , vol.311 , pp. 665-678
    • Miller, K.A.1    Barrow, J.2    Collinson, J.M.3    Davidson, S.4    Lear, M.5    Hill, R.E.6    Mackenzie, A.7
  • 74
    • 0035378321 scopus 로고    scopus 로고
    • Tufan AC and Tuan RS Wnt regulation of limb mesenchymal chondrogenesis is accompanied by altered N-cadherin-related functions. Faseb J 2001; 15:1436-8
    • Tufan AC and Tuan RS Wnt regulation of limb mesenchymal chondrogenesis is accompanied by altered N-cadherin-related functions. Faseb J 2001; 15:1436-8.
  • 75
    • 0036774718 scopus 로고    scopus 로고
    • Local extrinsic signals determine muscle and endothelial cell fate and patterning in the vertebrate limb
    • Kardon G, Campbell JK, and Tabin CJ Local extrinsic signals determine muscle and endothelial cell fate and patterning in the vertebrate limb. Dev Cell 2002; 3:533-45.
    • (2002) Dev Cell , vol.3 , pp. 533-545
    • Kardon, G.1    Campbell, J.K.2    Tabin, C.J.3
  • 76
    • 0038488949 scopus 로고    scopus 로고
    • Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration
    • Polesskaya A, Seale P, and Rudnicki MA Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell 2003; 113:841-52.
    • (2003) Cell , vol.113 , pp. 841-852
    • Polesskaya, A.1    Seale, P.2    Rudnicki, M.A.3
  • 77
    • 0035830506 scopus 로고    scopus 로고
    • Hartmann C and Tabin CJ Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 2001; 104:341-51.
    • Hartmann C and Tabin CJ Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 2001; 104:341-51.
  • 78
    • 0031149422 scopus 로고    scopus 로고
    • Rudnicki JA and Brown AM Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro. Dev Biol 1997; 185:104-18.
    • Rudnicki JA and Brown AM Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro. Dev Biol 1997; 185:104-18.
  • 79
    • 0029073744 scopus 로고
    • Murine Wnt-11 and Wnt-12 have temporally and spatially restricted expression patterns during embryonic development
    • Christiansen JH, Dennis CL, Wicking CA, Monkley SJ, Wilkinson DG, and Wainwright BJ Murine Wnt-11 and Wnt-12 have temporally and spatially restricted expression patterns during embryonic development. Mech Dev 1995; 51:341-50.
    • (1995) Mech Dev , vol.51 , pp. 341-350
    • Christiansen, J.H.1    Dennis, C.L.2    Wicking, C.A.3    Monkley, S.J.4    Wilkinson, D.G.5    Wainwright, B.J.6
  • 80
    • 0029889261 scopus 로고    scopus 로고
    • Christiansen JH, Monkley SJ, and Wainwright BJ Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cells. Oncogene 1996; 12:2705-11.
    • Christiansen JH, Monkley SJ, and Wainwright BJ Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cells. Oncogene 1996; 12:2705-11.
  • 81
    • 0033864484 scopus 로고    scopus 로고
    • Hartmann C and Tabin CJ Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development 2000; 127:3141-59.
    • Hartmann C and Tabin CJ Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development 2000; 127:3141-59.
  • 83
    • 18744415452 scopus 로고    scopus 로고
    • Comparative analysis of the expression patterns of Wnts during chick limb development
    • Loganathan PG, Nimmagadda S, Huang R, Scaal M, and Christ B Comparative analysis of the expression patterns of Wnts during chick limb development. Histochem Cell Biol 2005; 123:195-201.
    • (2005) Histochem Cell Biol , vol.123 , pp. 195-201
    • Loganathan, P.G.1    Nimmagadda, S.2    Huang, R.3    Scaal, M.4    Christ, B.5
  • 85
    • 0028815947 scopus 로고
    • Cloning and characterization of Wnt-4 and Wnt-11 cDNAs from chick embryo
    • Tanda N, Kawakami Y, Saito T, Noji S, and Nohno T Cloning and characterization of Wnt-4 and Wnt-11 cDNAs from chick embryo. DNA Seq 1995; 5:277-81.
    • (1995) DNA Seq , vol.5 , pp. 277-281
    • Tanda, N.1    Kawakami, Y.2    Saito, T.3    Noji, S.4    Nohno, T.5
  • 86
    • 0032805495 scopus 로고    scopus 로고
    • Successive formative stages of precartilaginous mesenchymal condensations in vitro: Modulation of cell adhesion by Wnt-7A and BMP-2
    • Stott NS, Jiang TX, and Chuong CM Successive formative stages of precartilaginous mesenchymal condensations in vitro: modulation of cell adhesion by Wnt-7A and BMP-2. J Cell Physiol 1999; 180:314-24.
    • (1999) J Cell Physiol , vol.180 , pp. 314-324
    • Stott, N.S.1    Jiang, T.X.2    Chuong, C.M.3
  • 88
    • 0036060527 scopus 로고    scopus 로고
    • Tufan AC, Daumer KM, DeLise AM, and Tuan RS AP-1 transcription factor complex is a target of signals from both WnT-7a and N-cadherin-dependent cell-cell adhesion complex during the regulation of limb mesenchymal chondrogenesis. Exp Cell Res 2002; 273:197-203.
    • Tufan AC, Daumer KM, DeLise AM, and Tuan RS AP-1 transcription factor complex is a target of signals from both WnT-7a and N-cadherin-dependent cell-cell adhesion complex during the regulation of limb mesenchymal chondrogenesis. Exp Cell Res 2002; 273:197-203.
  • 89
    • 0036152661 scopus 로고    scopus 로고
    • Frizzled-7 and limb mesenchymal chondrogenesis: Effect of misexpression and involvement of N-cadherin
    • Tufan AC, Daumer KM, and Tuan RS Frizzled-7 and limb mesenchymal chondrogenesis: effect of misexpression and involvement of N-cadherin. Dev Dyn 2002; 223:241-53.
    • (2002) Dev Dyn , vol.223 , pp. 241-253
    • Tufan, A.C.1    Daumer, K.M.2    Tuan, R.S.3
  • 90
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
    • Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, and Yang Y Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. J Cell Biol 2003; 162:899-908.
    • (2003) J Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 92
    • 33748148734 scopus 로고    scopus 로고
    • Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis
    • Spater D, Hill TP, O'Sullivan R J, Gruber M, Conner DA, and Hartmann C Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development 2006; 133:3039-49.
    • (2006) Development , vol.133 , pp. 3039-3049
    • Spater, D.1    Hill, T.P.2    O'Sullivan, R.J.3    Gruber, M.4    Conner, D.A.5    Hartmann, C.6
  • 93
    • 4644276225 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation
    • Guo X, Day TF, Jiang X, Garrett-Beal L, Topol L, and Yang Y Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev 2004; 18:2404-17.
    • (2004) Genes Dev , vol.18 , pp. 2404-2417
    • Guo, X.1    Day, T.F.2    Jiang, X.3    Garrett-Beal, L.4    Topol, L.5    Yang, Y.6
  • 94
    • 17844363974 scopus 로고    scopus 로고
    • Canonical Wnt/betacatenin signaling prevents osteoblasts from differentiating into chondrocytes
    • Hill TP, Spater D, Taketo MM, Birchmeier W, and Hartmann C Canonical Wnt/betacatenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell 2005; 8:727-38.
    • (2005) Dev Cell , vol.8 , pp. 727-738
    • Hill, T.P.1    Spater, D.2    Taketo, M.M.3    Birchmeier, W.4    Hartmann, C.5
  • 95
    • 0036845163 scopus 로고    scopus 로고
    • Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
    • Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, and Carson DA Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum 2002; 46:2867-77.
    • (2002) Arthritis Rheum , vol.46 , pp. 2867-2877
    • Sen, M.1    Reifert, J.2    Lauterbach, K.3    Wolf, V.4    Rubin, J.S.5    Corr, M.6    Carson, D.A.7
  • 97
    • 18044386744 scopus 로고    scopus 로고
    • Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Juppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, and Warman ML LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001; 107:513-23
    • Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Juppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, and Warman ML LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001; 107:513-23.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.