-
1
-
-
77954187741
-
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
-
Pommier Y, Leo E, Zhang H, Marchand C. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol 2010;17:421-33.
-
(2010)
Chem Biol
, vol.17
, pp. 421-433
-
-
Pommier, Y.1
Leo, E.2
Zhang, H.3
Marchand, C.4
-
2
-
-
33747889217
-
Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
-
DOI 10.1016/j.dnarep.2006.05.022, PII S1568786406001662, Mechanisms of Chromosomal Translocations
-
Sonoda E, Hochegger H, Saberi A, Taniguchi Y, Takeda S. Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair (Amst) 2006;5: 1021-9. (Pubitemid 44291617)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1021-1029
-
-
Sonoda, E.1
Hochegger, H.2
Saberi, A.3
Taniguchi, Y.4
Takeda, S.5
-
3
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori AA, Lukas C, Coates J, et al. Human CtIP promotes DNA end resection. Nature 2007;450:509-14.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
-
4
-
-
68249116573
-
DNA end resection: Many nucleases make light work
-
Amst
-
Mimitou EP, Symington LS. DNA end resection: many nucleases make light work. DNA Repair (Amst) 2009;8:983-95.
-
(2009)
DNA Repair
, vol.8
, pp. 983-995
-
-
Mimitou, E.P.1
Symington, L.S.2
-
5
-
-
65849336044
-
At loose ends: Resecting a double-strand break
-
Bernstein KA, Rothstein R. At loose ends: resecting a double-strand break. Cell 2009;137:807-10.
-
(2009)
Cell
, vol.137
, pp. 807-810
-
-
Bernstein, K.A.1
Rothstein, R.2
-
6
-
-
76749157216
-
Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair
-
Nakamura K, Kogame T, Oshiumi H, et al. Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. PLoS Genet 2010;6:e1000828.
-
(2010)
PLoS Genet
, vol.6
-
-
Nakamura, K.1
Kogame, T.2
Oshiumi, H.3
-
7
-
-
19944434079
-
Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination
-
Hatanaka A, Yamazoe M, Sale JE, et al. Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination. Mol Cell Biol 2005;25: 1124-34.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1124-1134
-
-
Hatanaka, A.1
Yamazoe, M.2
Sale, J.E.3
-
8
-
-
38049115657
-
The mechanism of human nonhomologous DNA end joining
-
Lieber MR. The mechanism of human nonhomologous DNA end joining. J Biol Chem 2008;283:1-5.
-
(2008)
J Biol Chem
, vol.283
, pp. 1-5
-
-
Lieber, M.R.1
-
9
-
-
64649090292
-
Targeting DNA topoisomerase II in cancer chemotherapy
-
Nitiss JL. Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer 2009;9:338-50.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 338-350
-
-
Nitiss, J.L.1
-
10
-
-
33749034730
-
Topoisomerase I inhibitors: Camptothecins and beyond
-
Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 2006;6:789-802.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 789-802
-
-
Pommier, Y.1
-
11
-
-
0141592619
-
Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: Implications for the repair of topoisomerase II-mediated DNA damage
-
DOI 10.1074/jbc.M306500200
-
Adachi N, Suzuki H, Iiizumi S, Koyama H. Hypersensitivity of non-homologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage. J Biol Chem 2003;278:35897-902. (Pubitemid 37139907)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.38
, pp. 35897-35902
-
-
Adachi, N.1
Suzuki, H.2
Iiizumi, S.3
Koyama, H.4
-
12
-
-
0024804442
-
Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors
-
Jeggo PA, Caldecott K, Pidsley S, Banks GR. Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors. Cancer Res 1989;49:7057-63. (Pubitemid 20016593)
-
(1989)
Cancer Research
, vol.49
, Issue.24
, pp. 7057-7063
-
-
Jeggo, P.A.1
Caldecott, K.2
Pidsley, S.3
Banks, G.R.4
-
13
-
-
0025147256
-
DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II
-
Caldecott K, Banks G, Jeggo P. DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II. Cancer Res 1990;50:5778-83. (Pubitemid 20331376)
-
(1990)
Cancer Research
, vol.50
, Issue.18
, pp. 5778-5783
-
-
Caldecott, K.1
Banks, G.2
Jeggo, P.3
-
14
-
-
4444327584
-
Loss of nonhomologous end joining confers camptothecin resistance in DT40 cells: Implications for the repair of topoisomerase I-mediated DNA damage
-
DOI 10.1074/jbc.M313910200
-
Adachi N, So S, Koyama H. Loss of nonhomologous end joining confers camptothecin resistance in DT40 cells. Implications for the repair of topoisomerase I-mediated DNA damage. J Biol Chem 2004;279: 37343-8. (Pubitemid 39195442)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.36
, pp. 37343-37348
-
-
Adachi, N.1
So, S.2
Koyama, H.3
-
15
-
-
14544268980
-
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
-
DOI 10.1038/nature03314
-
El-Khamisy SF, Saifi GM, Weinfeld M, et al. Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1. Nature 2005;434:108-13. (Pubitemid 40349394)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 108-113
-
-
El-Khamisy, S.F.1
Saifi, G.M.2
Weinfeld, M.3
Johansson, F.4
Helleday, T.5
Lupski, J.R.6
Caldecott, K.W.7
-
16
-
-
70349673605
-
A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage
-
Cortes Ledesma F, El Khamisy SF, Zuma MC, Osborn K, Caldecott KW. A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage. Nature 2009;461:674-8.
-
(2009)
Nature
, vol.461
, pp. 674-678
-
-
Cortes Ledesma, F.1
El Khamisy, S.F.2
Zuma, M.C.3
Osborn, K.4
Caldecott, K.W.5
-
17
-
-
23944459784
-
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
-
DOI 10.1038/nature03872
-
Neale MJ, Pan J, Keeney S. Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature 2005;436: 1053-7. (Pubitemid 41191692)
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 1053-1057
-
-
Neale, M.J.1
Pan, J.2
Keeney, S.3
-
18
-
-
58149289464
-
Distinct requirements for the Rad32 (Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA
-
Hartsuiker E, Neale MJ, Carr AM. Distinct requirements for the Rad32 (Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA. Mol Cell 2009;33:117-23.
-
(2009)
Mol Cell
, vol.33
, pp. 117-123
-
-
Hartsuiker, E.1
Neale, M.J.2
Carr, A.M.3
-
19
-
-
6344264992
-
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
-
Yu X, Chen J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol Cell Biol 2004;24:9478-86.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9478-9486
-
-
Yu, X.1
Chen, J.2
-
20
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B, Matsuoka S, Ballif BA, et al. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 2007;316:1194-8.
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
-
21
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian B, Shao G, Lilli DR, et al. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 2007;316: 1198-202.
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
-
22
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim H, Chen J, Yu X. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 2007;316: 1202-5.
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
23
-
-
34547120473
-
The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response
-
Yan J, Kim YS, Yang XP, et al. The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer Res 2007;67:6647-56.
-
(2007)
Cancer Res
, vol.67
, pp. 6647-6656
-
-
Yan, J.1
Kim, Y.S.2
Yang, X.P.3
-
24
-
-
62549140202
-
The Rap80-36 de-ubiquitinating enzyme complex antagonizes RNF8-13-dependent ubiquitination events at DNA double strand breaks
-
Shao G, Lilli DR, Patterson-Fortin J, Coleman KA, Morrissey DE, Greenberg RA. The Rap80-36 de-ubiquitinating enzyme complex antagonizes RNF8-13-dependent ubiquitination events at DNA double strand breaks. Proc Natl Acad Sci U S A 2009;106:3166-71.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3166-3171
-
-
Shao, G.1
Lilli, D.R.2
Patterson-Fortin, J.3
Coleman, K.A.4
Morrissey, D.E.5
Greenberg, R.A.6
-
25
-
-
0025936509
-
Increased ratio of targeted to random integration after transfection of chicken B cell lines
-
Buerstedde JM, Takeda S. Increased ratio of targeted to random integration after transfection of chicken B cell lines. Cell 1991;67: 179-88.
-
(1991)
Cell
, vol.67
, pp. 179-188
-
-
Buerstedde, J.M.1
Takeda, S.2
-
26
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
-
Takata M, Sasaki MS, Sonoda E, et al. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J 1998;17: 5497-508.
-
(1998)
EMBO J
, vol.17
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
-
27
-
-
35448968240
-
RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors
-
Martin RW, Orelli BJ, Yamazoe M, Minn AJ, Takeda S, Bishop DK. RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors. Cancer Res 2007;67: 9658-65.
-
(2007)
Cancer Res
, vol.67
, pp. 9658-9665
-
-
Martin, R.W.1
Orelli, B.J.2
Yamazoe, M.3
Minn, A.J.4
Takeda, S.5
Bishop, D.K.6
-
28
-
-
29244435019
-
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells
-
Nojima K, Hochegger H, Saberi A, et al. Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res 2005;65:11704-11.
-
(2005)
Cancer Res
, vol.65
, pp. 11704-11711
-
-
Nojima, K.1
Hochegger, H.2
Saberi, A.3
-
29
-
-
74949085703
-
A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants
-
Ji K, Kogame T, Choi K, et al. A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants. Environ Health Perspect 2009;117:1737-44.
-
(2009)
Environ Health Perspect
, vol.117
, pp. 1737-1744
-
-
Ji, K.1
Kogame, T.2
Choi, K.3
-
30
-
-
33847413700
-
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination
-
Zhao GY, Sonoda E, Barber LJ, et al. A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell 2007;25:663-75.
-
(2007)
Mol Cell
, vol.25
, pp. 663-675
-
-
Zhao, G.Y.1
Sonoda, E.2
Barber, L.J.3
-
31
-
-
34548807121
-
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells
-
Murakawa Y, Sonoda E, Barber LJ, et al. Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res 2007;67:8536-43.
-
(2007)
Cancer Res
, vol.67
, pp. 8536-8543
-
-
Murakawa, Y.1
Sonoda, E.2
Barber, L.J.3
-
32
-
-
0034604716
-
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
-
Bhattacharyya A, Ear US, Koller BH, Weichselbaum RR, Bishop DK. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 2000;275: 23899-903.
-
(2000)
J Biol Chem
, vol.275
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
Weichselbaum, R.R.4
Bishop, D.K.5
-
33
-
-
33750958146
-
BRCA1 ubiquitylation of CtIP: Just the tIP of the iceberg?
-
Amst
-
Barber LJ, Boulton SJ. BRCA1 ubiquitylation of CtIP: just the tIP of the iceberg? DNA Repair (Amst) 2006;5:1499-504.
-
(2006)
DNA Repair
, vol.5
, pp. 1499-1504
-
-
Barber, L.J.1
Boulton, S.J.2
-
34
-
-
63049112033
-
MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA doublestrand breaks
-
Shao G, Patterson-Fortin J, Messick TE, et al. MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA doublestrand breaks. Genes Dev 2009;23:740-54.
-
(2009)
Genes Dev
, vol.23
, pp. 740-754
-
-
Shao, G.1
Patterson-Fortin, J.2
Messick, T.E.3
-
35
-
-
0033604444
-
Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation
-
Takao N, Kato H, Mori R, et al. Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation. Oncogene 1999;18:7002-9.
-
(1999)
Oncogene
, vol.18
, pp. 7002-7009
-
-
Takao, N.1
Kato, H.2
Mori, R.3
-
36
-
-
50449098473
-
New players in the BRCA1-mediated DNA damage responsive pathway
-
Kim H, Chen J. New players in the BRCA1-mediated DNA damage responsive pathway. Mol Cells 2008;25:457-61.
-
(2008)
Mol Cells
, vol.25
, pp. 457-461
-
-
Kim, H.1
Chen, J.2
-
37
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen MS, Sy SM, Chen J. BRCA1 and its toolbox for the maintenance of genome integrity. Nat Rev Mol Cell Biol 2010;11: 138-48.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
38
-
-
70350763838
-
ATM and Artemis promote homologous recombination of radiation-induced DNA doublestrand breaks in G2
-
Beucher A, Birraux J, Tchouandong L, et al. ATM and Artemis promote homologous recombination of radiation-induced DNA doublestrand breaks in G2. EMBO J 2009;28:3413-27.
-
(2009)
EMBO J
, vol.28
, pp. 3413-3427
-
-
Beucher, A.1
Birraux, J.2
Tchouandong, L.3
-
39
-
-
31044441712
-
Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations
-
Nakada S, Katsuki Y, Imoto I, et al. Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations. J Clin Invest 2006;116:80-9.
-
(2006)
J Clin Invest
, vol.116
, pp. 80-89
-
-
Nakada, S.1
Katsuki, Y.2
Imoto, I.3
|