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Volumn 150, Issue 5, 2009, Pages 2036-2045

Mechanisms of resistance to structurally diverse antiestrogens differ under premenopausal and postmenopausal conditions: Evidence from in Vitro breast cancer cell models

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYTAMOXIFEN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; TAMOXIFEN; 4-HYDROXYTAMOXIFEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DRUG DERIVATIVE; EGFR PROTEIN, HUMAN; ESTROGEN RECEPTOR; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

EID: 66449117772     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1195     Document Type: Article
Times cited : (28)

References (44)
  • 1
    • 33847023585 scopus 로고    scopus 로고
    • Long-term treatment with tamoxifen facilitates translocation of estrogen receptor a out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells
    • Fan P, Wang J, Santen RJ, Yue W 2007 Long-term treatment with tamoxifen facilitates translocation of estrogen receptor a out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. Cancer Res 67:1352-1360
    • (2007) Cancer Res , vol.67 , pp. 1352-1360
    • Fan, P.1    Wang, J.2    Santen, R.J.3    Yue, W.4
  • 2
    • 8444222836 scopus 로고    scopus 로고
    • Cyclin D1 expression is dependent on estrogen receptor function in tamoxifen-resistant breast cancer cells
    • Kilker RL, Hartl MW, Rutherford TM, Planas-Silva MD 2004 Cyclin D1 expression is dependent on estrogen receptor function in tamoxifen-resistant breast cancer cells. J Steroid Biochem Mol Biol 92:63-71
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 63-71
    • Kilker, R.L.1    Hartl, M.W.2    Rutherford, T.M.3    Planas-Silva, M.D.4
  • 3
    • 0037373326 scopus 로고    scopus 로고
    • Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
    • Knowlden JM, Hutcheson IR, Jones HE, Madden T, Gee JM, Harper ME, Barrow D, Wakeling AE, Nicholson RI 2003 Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells. Endocrinology 144: 1032-1044
    • (2003) Endocrinology , vol.144 , pp. 1032-1044
    • Knowlden, J.M.1    Hutcheson, I.R.2    Jones, H.E.3    Madden, T.4    Gee, J.M.5    Harper, M.E.6    Barrow, D.7    Wakeling, A.E.8    Nicholson, R.I.9
  • 4
    • 0034987631 scopus 로고    scopus 로고
    • Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182, 780 (Faslodex)
    • McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, Knowlden JM, Gee JM, Nicholson RI 2001 Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182, 780 (Faslodex). Endocrinology 142:2776-2788
    • (2001) Endocrinology , vol.142 , pp. 2776-2788
    • McClelland, R.A.1    Barrow, D.2    Madden, T.A.3    Dutkowski, C.M.4    Pamment, J.5    Knowlden, J.M.6    Gee, J.M.7    Nicholson, R.I.8
  • 5
    • 0029883292 scopus 로고    scopus 로고
    • Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines
    • Pink JJ, Jordan VC 1996 Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines. Cancer Res 56:2321-2330
    • (1996) Cancer Res , vol.56 , pp. 2321-2330
    • Pink, J.J.1    Jordan, V.C.2
  • 6
    • 0025933431 scopus 로고
    • Antiestrogen resistance: Mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy
    • Katzenellenbogen BS 1991 Antiestrogen resistance: mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy. J Natl Cancer Inst 83:1434-1435
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1434-1435
    • Katzenellenbogen, B.S.1
  • 7
    • 15644377090 scopus 로고    scopus 로고
    • MCF7/LCC9: An antiestro- gen-resistant MCF-7 variant in which acquired resistance to the steroidal an- tiestrogen ICI 182, 780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen
    • Brunner N, Boysen B, Jirus S, Skaar TC, Holst-Hansen C, LippmanJ, Frandsen T, Spang-Thomsen M, Fuqua SA, Clarke R 1997 MCF7/LCC9: an antiestro- gen-resistant MCF-7 variant in which acquired resistance to the steroidal an- tiestrogen ICI 182, 780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen. Cancer Res 57:3486-3493
    • (1997) Cancer Res , vol.57 , pp. 3486-3493
    • Brunner, N.1    Boysen, B.2    Jirus, S.3    Skaar, T.C.4    Holst-Hansen, C.5    Lippman, J.6    Frandsen, T.7    Spang-Thomsen, M.8    Fuqua, S.A.9    Clarke, R.10
  • 8
    • 0028329961 scopus 로고
    • Altered expression of estrogen- regulated genes in a tamoxifen-resistant and ICI 164, 384 and ICI 182, 780 sensitive human breast cancer cell line, MCF-7/TAMR-1
    • Lykkesfeldt AE, Madsen MW, Briand P 1994 Altered expression of estrogen- regulated genes in a tamoxifen-resistant and ICI 164, 384 and ICI 182, 780 sensitive human breast cancer cell line, MCF-7/TAMR-1. Cancer Res 54:1587-1595
    • (1994) Cancer Res , vol.54 , pp. 1587-1595
    • Lykkesfeldt, A.E.1    Madsen, M.W.2    Briand, P.3
  • 9
    • 0026068370 scopus 로고
    • Acquired tamoxifen resistance: Correlation with reduced breast tumor levels of tamox- ifen and isomerization of trans-4-hydroxytamoxifen
    • Osborne CK, Coronado E, AllredDC, Wiebe V, DeGregorio M 1991 Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamox- ifen and isomerization of trans-4-hydroxytamoxifen. J Natl Cancer Inst 83: 1477-1482
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1477-1482
    • Osborne, C.K.1    Coronado, E.2    Allred, D.C.3    Wiebe, V.4    DeGregorio, M.5
  • 12
    • 0036721523 scopus 로고    scopus 로고
    • Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol
    • Yue W, Wang JP, Conaway M, Masamura S, Li Y, Santen RJ2002 Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol. Endocrinology 143:3221-3229
    • (2002) Endocrinology , vol.143 , pp. 3221-3229
    • Yue, W.1    Wang, J.P.2    Conaway, M.3    Masamura, S.4    Li, Y.5    Santen, R.J.6
  • 15
    • 34250878367 scopus 로고    scopus 로고
    • Superiority of gas chromatography/tandem mass spectrom- etry assay (GC/MS/MS) for estradiol for monitoring of aromatase inhibitor therapy
    • Santen RJ, Demers L, Ohorodnik S, Settlage J, Langecker P, Blanchett D, Goss PE, Wang S 2007 Superiority of gas chromatography/tandem mass spectrom- etry assay (GC/MS/MS) for estradiol for monitoring of aromatase inhibitor therapy. Steroids 72:666 -671
    • (2007) Steroids , vol.72 , pp. 666-671
    • Santen, R.J.1    Demers, L.2    Ohorodnik, S.3    Settlage, J.4    Langecker, P.5    Blanchett, D.6    Goss, P.E.7    Wang, S.8
  • 18
    • 0027232052 scopus 로고
    • Estrone sulfate promotes human breastcancer cellreplicationand nuclear uptakeofestradiolinMCF-7 cell cultures
    • Santner SJ, Ohlsson-Wilhelm B, Santen RJ 1993 Estrone sulfate promotes human breastcancer cellreplicationand nuclear uptakeofestradiolinMCF-7 cell cultures. Int JCancer 54:119-124
    • (1993) Int JCancer , vol.54 , pp. 119-124
    • Santner, S.J.1    Ohlsson-Wilhelm, B.2    Santen, R.J.3
  • 19
    • 2542464918 scopus 로고
    • Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture
    • Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS 1986 Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 83:2496-2500
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2496-2500
    • Berthois, Y.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 24
    • 33745839812 scopus 로고    scopus 로고
    • unctional screen for genes responsible for tamoxifen resistance in human breast cancer cells
    • Meijer D, van Agthoven T, Bosma PT, Nooter K, Dorssers LC2006Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells. Mol Cancer Res 4:379-386
    • (2006) Mol Cancer Res , vol.4 , pp. 379-386
    • Meijer, D.1    van Agthoven, T.2    Bosma, P.T.3    Nooter, K.4    Dorssers, L.C.5
  • 25
    • 0018943330 scopus 로고
    • High-affinity binding to the estrogen receptor of [3H]4-hydroxytamoxifen, an active antiestrogen metabolite
    • Borgna JL, Rochefort H 1980 High-affinity binding to the estrogen receptor of [3H]4-hydroxytamoxifen, an active antiestrogen metabolite. Mol Cell En- docrinol 20:71-85
    • (1980) Mol Cell En- docrinol , vol.20 , pp. 71-85
    • Borgna, J.L.1    Rochefort, H.2
  • 27
    • 0027521287 scopus 로고
    • Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain
    • Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW 1993 Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol 7:1266 -1274
    • (1993) Mol Endocrinol , vol.7 , pp. 1266-1274
    • Beekman, J.M.1    Allan, G.F.2    Tsai, S.Y.3    Tsai, M.J.4    O'Malley, B.W.5
  • 29
    • 0026560435 scopus 로고
    • AntiestrogenICI 164, 384 reduces cellular estrogen receptor content by increasing its turnover
    • Dauvois S, Danielian PS, White R, Parker MG 1992 AntiestrogenICI 164, 384 reduces cellular estrogen receptor content by increasing its turnover. Proc Natl Acad Sci USA 89:4037-4041
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4037-4041
    • Dauvois, S.1    Danielian, P.S.2    White, R.3    Parker, M.G.4
  • 31
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, Weiss H, SchiffR 2004 Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96:926-935
    • (2004) J Natl Cancer Inst , vol.96 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    Ali, S.5    Weiss, H.6    SchiffR7
  • 33
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164, 384 appears to be mediated by impaired receptor dimerization
    • Fawell SE, White R, Hoare S, Sydenham M, Page M, Parker MG 1990 Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164, 384 appears to be mediated by impaired receptor dimerization. Proc Natl Acad Sci USA 87:6883-6887
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3    Sydenham, M.4    Page, M.5    Parker, M.G.6
  • 34
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182, 780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois S, White R, Parker MG 1993 The antiestrogen ICI 182, 780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 106:1377-1388
    • (1993) J Cell Sci , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 35
    • 0015898197 scopus 로고
    • Estrogen receptor in a human cell line (MCF-7) from breast carcinoma
    • Brooks SC, Locke ER, Soule HD 1973 Estrogen receptor in a human cell line (MCF-7) from breast carcinoma. J Biol Chem 248:6251-6253
    • (1973) J Biol Chem , vol.248 , pp. 6251-6253
    • Brooks, S.C.1    Locke, E.R.2    Soule, H.D.3
  • 36
    • 0015762456 scopus 로고
    • A human cell line from a pleural effusion derived from a breast carcinoma
    • Soule HD, Vazguez J, Long A, Albert S, Brennan M 1973 A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51:1409-1416
    • (1973) J Natl Cancer Inst , vol.51 , pp. 1409-1416
    • Soule, H.D.1    Vazguez, J.2    Long, A.3    Albert, S.4    Brennan, M.5
  • 37
    • 0033429237 scopus 로고    scopus 로고
    • Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family
    • Larsen SS, Egeblad M, Jaattela M, Lykkesfeldt AE 1999 Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family. Breast Cancer Res Treat 58:41-56
    • (1999) Breast Cancer Res Treat , vol.58 , pp. 41-56
    • Larsen, S.S.1    Egeblad, M.2    Jaattela, M.3    Lykkesfeldt, A.E.4
  • 38
    • 18044398983 scopus 로고    scopus 로고
    • Reversal oftamoxifenresistant breast cancer by low dose estrogen therapy
    • Osipo C, Gajdos C, Cheng D, Jordan VC2005 Reversal oftamoxifenresistant breast cancer by low dose estrogen therapy. J Steroid Biochem Mol Biol 93: 249-256
    • (2005) J Steroid Biochem Mol Biol , vol.93 , pp. 249-256
    • Osipo, C.1    Gajdos, C.2    Cheng, D.3    Jordan, V.C.4
  • 39
    • 34249845380 scopus 로고    scopus 로고
    • Characterization of a novel tripartite nuclear localization sequence in the EGFR family
    • Hsu SC, Hung MC 2007 Characterization of a novel tripartite nuclear localization sequence in the EGFR family. JBiol Chem 282:10432-10440
    • (2007) JBiol Chem , vol.282 , pp. 10432-10440
    • Hsu, S.C.1    Hung, M.C.2
  • 40
    • 33746561717 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, im- portin 01 and CRM1
    • Lo HW, Ali-Seyed M, Wu Y, Bartholomeusz G, Hsu SC, Hung MC 2006 Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, im- portin 01 and CRM1. J Cell Biochem 98:1570-1583
    • (2006) J Cell Biochem , vol.98 , pp. 1570-1583
    • Lo, H.W.1    Ali-Seyed, M.2    Wu, Y.3    Bartholomeusz, G.4    Hsu, S.C.5    Hung, M.C.6
  • 41
    • 0036069975 scopus 로고    scopus 로고
    • Local uptake and synthesis of oestrone in normal and malignant postmenopausal breast tissues
    • Larionov AA, Berstein LM, Miller WR 2002 Local uptake and synthesis of oestrone in normal and malignant postmenopausal breast tissues. J Steroid Biochem Mol Biol 81:57-64
    • (2002) J Steroid Biochem Mol Biol , vol.81 , pp. 57-64
    • Larionov, A.A.1    Berstein, L.M.2    Miller, W.R.3
  • 42
    • 0032031754 scopus 로고    scopus 로고
    • In situ aroma- tization enhances breast tumor estradiol levels and cellular proliferation
    • Yue W, Wang JP, HamiltonCJ, Demers LM, SantenRJ 1998 In situ aroma- tization enhances breast tumor estradiol levels and cellular proliferation. Cancer Res 58:927-932
    • (1998) Cancer Res , vol.58 , pp. 927-932
    • Yue, W.1    Wang, J.P.2    Hamilton, C.J.3    Demers, L.M.4    Santen, R.J.5
  • 43
  • 44
    • 0021931084 scopus 로고
    • Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue
    • van Landeghem AA, Poortman, J, Nabuurs M, Thijssen JH 1985 Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue. Cancer Res 45:2900 -2906
    • (1985) Cancer Res , vol.45 , pp. 2900-2906
    • van Landeghem, A.A.1    Poortman, J.2    Nabuurs, M.3    Thijssen, J.H.4


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