Characterization and immune function of two intracellular sensors, HmTLR1 and HmNLR, in the injured CNS of an invertebrate

Developmental and Comparative Immunology

Volumn 35, Issue 2, 2011, Pages 214-226

  Cuvillier Hot, Virginie ^a   Boidin Wichlacz, Céline ^a   Slomianny, Christian ^a   Salzet, Michel ^a   Tasiemski, Aurélie ^a  

^a UNIV LILLE   (France)

Author keywords

Hirudo medicinalis; Invertebrate; Medicinal leech; Neuroimmunity; Nod like receptor; Toll like receptor

Indexed keywords

NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR C3; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 13; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM INJURY; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; ENDOSOME; IMMUNE RESPONSE; LEECH; NERVE CELL; NERVE REGENERATION; NEUROIMMUNOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; RECEPTOR UPREGULATION; SEQUENCE HOMOLOGY;

HIRUDINIDA; HIRUDO MEDICINALIS; INVERTEBRATA; MAMMALIA;

EID: 78449266452     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2010.09.011     Document Type: Article

References (58)

1. Ao J.Q., Ling E., Yu X.Q. A toll receptor from Manduca sexta is in response to Escherichia coli infection. Mol. Immunol. 2008, 45:543-552.
2. Aravalli R.N., Peterson P.K., Lokensgard J.R. Toll-like receptors in defense and damage of the central nervous system. J. Neuroimmune Pharmacol. 2007, 2:297-312.
3. Barnich N., Aguirre J.E., Reinecker H.C., Xavier R., Podolsky D.K. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition. J. Cell Biol. 2005, 170:21-26.
4. Benko S., Philpott D.J., Girardin S.E. The microbial and danger signals that activate Nod-like receptors. Cytokine 2008, 43:368-373.
5. Bsibsi M., Persoon-Deen C., Verwer R.W., Meeuwsen S., Ravid R., Van Noort J.M. Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators. Glia 2006, 53:688-695.
6. Bsibsi M., Ravid R., Gveric D., van Noort J.M. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 2002, 61:1013-1021.
7. Cameron J.S., Alexopoulou L., Sloane J.A., DiBernardo A.B., Ma Y., Kosaras B., Flavell R., Strittmatter S.M., Volpe J., Sidman R., Vartanian T. Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals. J. Neurosci. 2007, 27:13033-13041.
8. Chauhan V.S., Sterka D.G., Furr S.R., Young A.B., Marriott I. NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens. Glia 2009, 57:414-423.
9. Conti B.J., Davis B.K., Zhang J., O'Connor W., Williams K.L., Ting J.P. CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. J. Biol. Chem. 2005, 280:18375-18385.
10. Davidson C.R., Best N.M., Francis J.W., Cooper E.L., Wood T.C. Toll-like receptor genes (TLRs) from Capitella capitata and Helobdella robusta (Annelida). Dev. Comp. Immunol. 2008, 32:608-612.
11. de Rivero Vaccari J.P., Lotocki G., Alonso O.F., Bramlett H.M., Dietrich W.D., Keane R.W. Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. J. Cereb. Blood Flow Metab. 2009, 29:1251-1261.
12. Dereeper A., Guignon V., Blanc G., Audic S., Buffet S., Chevenet F., Dufayard J.F., Guindon S., Lefort V., Lescot M., Claverie J.M., Gascuel O. Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res. 2008, 36:W465-469.
13. Dolan J., Walshe K., Alsbury S., Hokamp K., O'Keeffe S., Okafuji T., Miller S.F., Tear G., Mitchell K.J. The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genom. 2007, 8:320.
14. Eming S.A., Hammerschmidt M., Krieg T., Roers A. Interrelation of immunity and tissue repair or regeneration. Semin. Cell Dev. Biol. 2009, 20:517-527.
15. Frederick Lo C., Ning X., Gonzales C., Ozenberger B.A. Induced expression of death domain genes NALP1 and NALP5 following neuronal injury. Biochem. Biophys. Res. Commun. 2008, 366:664-669.
16. Hibino T., Loza-Coll M., Messier C., Majeske A.J., Cohen A.H., Terwilliger D.P., Buckley K.M., Brockton V., Nair S.V., Berney K., Fugmann S.D., Anderson M.K., Pancer Z., Cameron R.A., Smith L.C., Rast J.P. The immune gene repertoire encoded in the purple sea urchin genome. Dev. Biol. 2006, 300:349-365.
17. Huang S., Yuan S., Guo L., Yu Y., Li J., Wu T., Liu T., Yang M., Wu K., Liu H., Ge J., Huang H., Dong M., Yu C., Chen S., Xu A. Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity. Genome Res. 2008, 18:1112-1126.
18. Hughes A.L. Evolutionary relationships of vertebrate NACHT domain-containing proteins. Immunogenetics 2006, 58:785-791.
19. Imler J.L., Zheng L. Biology of Toll receptors: lessons from insects and mammals. J. Leukoc. Biol. 2004, 75:18-26.
20. Inohara N., Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 2003, 3:371-382.
21. Jackson A.C., Rossiter J.P., Lafon M. Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases. J. Neurovirol. 2006, 12:229-234.
22. Jeru I., Duquesnoy P., Fernandes-Alnemri T., Cochet E., Yu J.W., Lackmy-Port-Lis M., Grimprel E., Landman-Parker J., Hentgen V., Marlin S., McElreavey K., Sarkisian T., Grateau G., Alnemri E.S., Amselem S. Mutations in NALP12 cause hereditary periodic fever syndromes. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:1614-1619.
23. Jin M.S., Lee J.O. Structures of the toll-like receptor family and its ligand complexes. Immunity 2008, 29:182-191.
24. Kielian T. Overview of toll-like receptors in the CNS. Curr. Top. Microbiol. Immunol. 2009, 336:1-14.
25. Kufer T.A., Kremmer E., Banks D.J., Philpott D.J. Role for erbin in bacterial activation of Nod2. Infect. Immun. 2006, 74:3115-3124.
26. Lafon M., Megret F., Lafage M., Prehaud C. The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA. J. Mol. Neurosci. 2006, 29:185-194.
27. Laing K.J., Purcell M.K., Winton J.R., Hansen J.D. A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish. BMC Evol. Biol. 2008, 8:42.
28. Leulier F., Lemaitre B. Toll-like receptors-taking an evolutionary approach. Nat. Rev. Genet. 2008, 9:165-178.
29. Lich J.D., Ting J.P. Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD NLR) proteins with negative regulatory functions. Microb. Infect. 2007, 9:672-676.
30. Lord C.A., Savitsky D., Sitcheran R., Calame K., Wright J.R., Ting J.P., Williams K.L. Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1. J. Immunol. 2009, 182:2948-2958.
31. McGettrick A.F., O'Neill L.A. Localisation and trafficking of Toll-like receptors: an important mode of regulation. Curr. Opin. Immunol. 2010, 22:20-27.
32. Mishra B.B., Gundra U.M., Teale J.M. Expression and distribution of Toll-like receptors 11-13 in the brain during murine neurocysticercosis. J. Neuroinflammation 2008, 5:53.
33. Morgese V.J., Elliott E.J., Muller K.J. Microglial movement to sites of nerve lesion in the leech CNS. Brain Res. 1983, 272:166-170.
34. Muller K.J., Carbonetto S. The morphological and physiological properties of a regenerating synapse in the C.N.S. of the leech. J. Comp. Neurol. 1979, 185:485-516.
35. Nagao S., Tanaka A., Onozaki K., Hashimoto T. Differences between macrophage migration inhibitions by lymphokines and muramyl dipeptide (MDP) or lipopolysaccharide (LPS): migration enhancement by lymphokines. Cell Immunol. 1982, 71:1-11.
36. Nagao S., Tanaka A., Yamamoto Y., Koga T., Onoue K., Shiba T., Kusumoto K., Kotani S. Inhibition of macrophage migration by muramyl peptides. Infect. Immun. 1979, 24:308-312.
37. Nguyen M.D., Julien J.P., Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration?. Nat. Rev. Neurosci. 2002, 3:216-227.
38. Povelones M., Waterhouse R.M., Kafatos F.C., Christophides G.K. Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites. Science 2009, 324:258-261.
39. Powell J.R., Kim D.H., Ausubel F.M. The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:2782-2787.
40. Pradel E., Zhang Y., Pujol N., Matsuyama T., Bargmann C.I., Ewbank J.J. Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:2295-2300.
41. Prehaud C., Megret F., Lafage M., Lafon M. Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon. J. Virol. 2005, 79:12893-12904.
42. Rast J.P., Smith L.C., Loza-Coll M., Hibino T., Litman G.W. Genomic insights into the immune system of the sea urchin. Science 2006, 314:952-956.
43. Salminen A., Ojala J., Suuronen T., Kaarniranta K., Kauppinen A. Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. J. Cell Mol. Med. 2008, 12:2255-2262.
44. Schikorski D., Cuvillier-Hot V., Boidin-Wichlacz C., Slomianny C., Salzet M., Tasiemski A. Deciphering the immune function and regulation by a TLR of the cytokine EMAPII in the lesioned central nervous system using a leech model. J. Immunol. 2009, 183:7119-7128.
45. Schikorski D., Cuvillier-Hot V., Leippe M., Boidin-Wichlacz C., Slomianny C., Macagno E., Salzet M., Tasiemski A. Microbial challenge promotes the regenerative process of the injured central nervous system of the medicinal leech by inducing the synthesis of antimicrobial peptides in neurons and microglia. J. Immunol. 2008, 181:1083-1095.
46. Schultz J., Milpetz F., Bork P., Ponting C.P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:5857-5864.
47. Sha Z., Abernathy J.W., Wang S., Li P., Kucuktas H., Liu H., Peatman E., Liu Z. NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish. Dev. Comp. Immunol. 2009, 33:991-999.
48. Sterka D., Rati D.M., Marriott I. Functional expression of NOD2, a novel pattern recognition receptor for bacterial motifs, in primary murine astrocytes. Glia 2006, 53:322-330.
49. Tahtouh M., Croq F., Vizioli J., Sautiere P.E., Van Camp C., Salzet M., Daha M.R., Pestel J., Lefebvre C. Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord. Mol. Immunol. 2009, 46:523-531.
50. Vercammen E., Staal J., Beyaert R. Sensing of viral infection and activation of innate immunity by toll-like receptor 3. Clin. Microbiol. Rev. 2008, 21:13-25.
51. Wang W.Z., Emes R.D., Christoffers K., Verrall J., Blackshaw S.E. Hirudo medicinalis: a platform for investigating genes in neural repair. Cell Mol. Neurobiol. 2005, 25:427-440.
52. Wharton K.A., Crews S.T. CNS midline enhancers of the Drosophila slit and Toll genes. Mech. Dev. 1993, 40:141-154.
53. Williams K.L., Lich J.D., Duncan J.A., Reed W., Rallabhandi P., Moore C., Kurtz S., Coffield V.M., Accavitti-Loper M.A., Su L., Vogel S.N., Braunstein M., Ting J.P. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. J. Biol. Chem. 2005, 280:39914-39924.
54. Wilmanski J.M., Petnicki-Ocwieja T., Kobayashi K.S. NLR proteins: integral members of innate immunity and mediators of inflammatory diseases. J. Leukoc. Biol. 2008, 83:13-30.
55. Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., Takeuchi O., Sugiyama M., Okabe M., Takeda K., Akira S. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003, 301:640-643.
56. Ye Z., Ting J.P. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Curr. Opin. Immunol. 2008, 20:3-9.
57. Zhang D., Zhang G., Hayden M.S., Greenblatt M.B., Bussey C., Flavell R.A., Ghosh S. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004, 303:1522-1526.
58. Zhang Z., Trautmann K., Schluesener H.J. Microglia activation in rat spinal cord by systemic injection of TLR3 and TLR7/8 agonists. J. Neuroimmunol. 2005, 164:154-160.