Erratum: Biological pathways and genetic variables involved in pain (Quality of Life Research (2010) 19 (1407-1417) DOI: 10.1007/s11136-010-9738-x);Biological pathways and genetic variables involved in pain

Quality of Life Research

Volumn 19, Issue 10, 2010, Pages 1407-1417

  Shi, Qiuling ^a   Cleeland, Charles S ^a   Klepstad, Pål ^b   Miaskowski, Christine ^c   Pedersen, Nancy L ^d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Analgesic efficacy; Biological pathways; Genetic polymorphism; Pain

Indexed keywords

ANALGESIC AGENT; CYTOCHROME P450; GLYCOPROTEIN P;

GENETICS; HUMAN; INFLAMMATION; NOCICEPTION; PAIN; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SYNAPTIC TRANSMISSION;

ANALGESICS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; INFLAMMATION; P-GLYCOPROTEIN; PAIN; PAIN PERCEPTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SYNAPTIC TRANSMISSION;

EID: 78349309752     PISSN: 09629343     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11136-010-9797-z     Document Type: Erratum

References (105)

1. F Aubrun O Langeron C Quesnel P Coriat B Riou 2003 Relationships between measurement of pain using visual analog score and morphine requirements during postoperative intravenous morphine titration Anesthesiology 98 6 1415 1421 1:CAS:528:DC%2BD3sXksVamtLk%3D 12766651
2. P Klepstad O Dale S Kaasa K Zahlsen T Aamo P Fayers, et al. 2003 Influences on serum concentrations of morphine, M6G and M3G during routine clinical drug monitoring: a prospective survey in 300 adult cancer patients Acta Anaesthesiologica Scandinavica 47 6 725 731 1:CAS:528:DC%2BD3sXmtVGisr0%3D 12803591
3. MA Sprangers JA Sloan R Veenhoven CS Cleeland MY Halyard AP Abertnethy, et al. 2009 The establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes Twin Research and Human Genetics 12 3 301 311 19456223
4. T Lotta J Vidgren C Tilgmann I Ulmanen K Melén I Julkunen, et al. 1995 Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme Biochemistry 34 13 4202 4210 1:CAS:528:DyaK2MXks1Kisrc%3D 7703232
5. JK Zubieta MM Heitzeg YR Smith JA Bueller K Xu Y Xu, et al. 2003 COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor Science 299 5610 1240 1243 1:CAS:528:DC%2BD3sXht12jtbc%3D 12595695
6. AG Nackley SA Shabalina IE Tchivileva K Satterfield O Korchynskyi SS Makarov, et al. 2006 Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure Science 314 5807 1930 1933 1:CAS:528:DC%2BD28Xhtlemt7bF 17185601
7. L Diatchenko GD Slade AG Nackley K Bhalang A Sigurdsson I Belfer, et al. 2005 Genetic basis for individual variations in pain perception and the development of a chronic pain condition Human Molecular Genetics 14 1 135 143 1:CAS:528:DC%2BD2MXitFGlsA%3D%3D 15537663
8. TT Rakvåg JR Ross H Sato F Skorpen S Kaasa P Klepstad 2008 Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain Molecular Pain 4 64 19094200
9. JR Ross J Riley AB Taegetmeyer H Sato S Gretton RM du Bois, et al. 2008 Genetic variation and response to morphine in cancer patients: Catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects Cancer 112 6 1390 1403 1:CAS:528: DC%2BD1cXksFKisro%3D 18257092
10. CB Pert SH Snyder 1973 Opiate receptor: Demonstration in nervous tissue Science 179 77 1011 1014 1:CAS:528:DyaE3sXktVShs7k%3D 4687585
11. C Stein 1993 Peripheral mechanisms of opioid analgesia Anesthesia and Analgesia 76 1 182 191 1:STN:280:DyaK3s7hvV2juw%3D%3D 8380316
12. JM Bidlack M Khimich AL Parkhill S Sumagin B Sun CM Tipton 2006 Opioid receptors and signaling on cells from the immune system Journal of Neuroimmune Pharmacology 1 3 260 269 18040803
13. H McQuay 1999 Opioids in pain management Lancet 353 9171 2229 2232 1:STN:280:DyaK1MzitVWksA%3D%3D 10393001
14. M Satoh M Minami 1995 Molecular pharmacology of the opioid receptors Pharmacology and Therapeutics 68 3 343 364 1:CAS:528:DyaK28Xis1Ortw%3D%3D 8788562
15. C Bond KS LaForge M Tian D Melia S Zhang L Borg, et al. 1998 Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction Proceedings of the National Academy of Sciences of the United States of America 95 16 9608 9613 1:CAS:528:DyaK1cXltlClsbY%3D 9689128
16. BG Oertel M Kettner K Scholich C Renné B Roskam G Geisslinger, et al. 2009 A common human {micro}-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain The Journal of Biological Chemistry 284 10 6530 6535 1:CAS:528:DC%2BD1MXisVSrsb0%3D 19116204
17. AT Sia Y Lim EC Lim RW Goh HY Law R Landau, et al. 2008 A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia Anesthesiology 109 3 520 526 1:CAS:528:DC%2BD1cXhtVWntr7E 18719451
18. WY Chou CH Wang PH Liu CC Liu CC Tseng B Jawan 2006 Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy Anesthesiology 105 2 334 337 1:CAS:528:DC%2BD28Xntl2mtb8%3D 16871067
19. P Klepstad TT Rakvåg S Kaasa M Holthe O Dale PC Borchgrevink, et al. 2004 The 118 A>G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease Acta Anaesthesiologica Scandinavica 48 10 1232 1239 1:CAS:528: DC%2BD2cXhtVOqtL%2FN 15504181
20. R Landau C Kern MO Columb RM Smiley JL Blouin 2008 Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women Pain 139 1 5 14 1:CAS:528:DC%2BD1cXhtFCgur3F 18403122
21. RD Blakely LJ De Felice HC Hartzell 1994 Molecular physiology of norepinephrine and serotonin transporters Journal of Experimental Biology 196 263 281 1:CAS:528:DyaK2MXivFWrtbc%3D 7823027
22. KP Lesch D Bengel A Heils SZ Sabol BD Greenberg S Petri, et al. 1996 Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 5292 1527 1531 1:CAS:528:DyaK28Xnt1ansL8%3D 8929413
23. A Heils A Teufel S Petri G Stöber P Riederer D Bengel, et al. 1996 Allelic variation of human serotonin transporter gene expression Journal of Neurochemistry 66 6 2621 2624 1:CAS:528:DyaK28XjtFCrsrk%3D 8632190
24. E Kosek KB Jensen TB Lonsdorf M Schalling M Ingvar 2009 Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans Molecular pain 5 37 19570226
25. H Herken E Erdal N Mutlu O Barlas O Cataloluk F Oz, et al. 2001 Possible association of temporomandibular joint pain and dysfunction with a polymorphism in the serotonin transporter gene American Journal of Orthodontics and Dentofacial Orthopedics 120 3 308 313 1:STN:280:DC%2BD3Mrgt1Okug%3D%3D 11552131
26. I Tegeder M Costigan RS Griffin A Abele I Belfer H Schmidt, et al. 2006 GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence Nature Medicine 12 11 1269 1277 1:CAS:528:DC%2BD28XhtFKlsLbK 17057711
27. J Lötsch I Belfer A Kirchhof BK Mishra MB Max A Doehring, et al. 2007 Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms Clinical Chemistry 53 6 1010 1015 17363416
28. GM Story AM Peier AJ Reeve SR Eid J Mosbacher TR Hricik, et al. 2003 ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures Cell 112 6 819 829 1:CAS:528:DC%2BD3sXivVWjsbk%3D 12654248
29. H Kim DP Mittal MJ Iadarola RA Dionne 2006 Genetic predictors for acute experimental cold and heat pain sensitivity in humans Journal of Medical Genetics 43 8 e40 1:STN:280:DC%2BD28vlvFOiug%3D%3D 16882734
30. MJ Caterina MA Schumacher M Tominaga TA Rosen JD Levine D Julius 1997 The capsaicin receptor: A heat-activated ion channel in the pain pathway Nature 389 6653 816 824 1:CAS:528:DyaK2sXmvFSksbs%3D 9349813
31. H Kim JK Neubert A San Miguel K Xu RK Krishnaraju MJ Iadarola, et al. 2004 Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament Pain 109 3 488 496 15157710
32. AH Lichtman CC Shelton T Advani BF Cravatt 2004 Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia Pain 109 3 319 327 1:CAS:528:DC%2BD2cXkt1SltL4%3D 15157693
33. KP Chiang AL Gerber JC Sipe BF Cravatt 2004 Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: Evidence for a link between defects in the endocannabinoid system and problem drug use Human Molecular Genetics 13 18 2113 2119 1:CAS:528:DC%2BD2cXnsVyisrg%3D 15254019
34. S Raimondi F Sera S Gandini S Iodice S Caini P Maisonneuve, et al. 2008 MC1R variants, melanoma and red hair color phenotype: A meta-analysis International Journal of Cancer 122 12 2753 2760 1:CAS:528:DC%2BD1cXht1eku7rJ
35. EB Liem TV Joiner K Tsueda DI Sessler 2005 Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads Anesthesiology 102 3 509 514 1:CAS:528:DC%2BD2MXhsF2ltb0%3D 15731586
36. JS Mogil SG Wilson EJ Chesler AL Rankin KV Nemmani WR Lariviere, et al. 2003 The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans Proceedings of the National Academy of Sciences of the United States of America 100 8 4867 4872 1:CAS:528:DC%2BD3sXjt12ntrg%3D 12663858
37. JS Mogil J Ritchie SB Smith K Strasburg L Kaplan MR Wallace, et al. 2005 Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans Journal of Medical Genetics 42 7 583 587 1:CAS:528: DC%2BD2MXnsVehsbw%3D 15994880
38. BN Lee R Dantzer KE Langley GJ Bennett PM Dougherty AJ Dunn, et al. 2004 A cytokine-based neuroimmunologic mechanism of cancer-related symptoms Neuroimmunomodulation 11 5 279 292 1:CAS:528:DC%2BD2cXmslCgt7w%3D 15316238
39. SF Maier LR Watkins 2003 Immune-to-central nervous system communication and its role in modulating pain and cognition: Implications for cancer and cancer treatment Brain, Behavior, and Immunity 17 Suppl 1 S125 S131 1:CAS:528:DC%2BD3sXhsVCgsLs%3D 12615198
40. SB Oh PB Tran SE Gillard RW Hurley DL Hammond RJ Miller 2001 Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons Journal of Neuroscience 21 14 5027 5035 1:CAS:528: DC%2BD3MXkvFSku7s%3D 11438578
41. GJ Bennett YK Xie 1988 A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man Pain 33 1 87 107 1:STN:280:DyaL1c3kslGhsw%3D%3D 2837713
42. GJ Bennett 1999 Does a neuroimmune interaction contribute to the genesis of painful peripheral neuropathies? Proceedings of the National Academy of Sciences of the United States of America 96 14 7737 7738 1:CAS:528: DyaK1MXltVOktrk%3D 10393890
43. GJ Bennett 2000 A neuroimmune interaction in painful peripheral neuropathy Clinical Journal of Pain 16 3 Suppl S139 S143 1:STN:280: DC%2BD3cvmt1CjtQ%3D%3D 11014458
44. AJ Reeve S Patel A Fox K Walker L Urban 2000 Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat European Journal of Pain: Ejp 4 3 247 257 1:CAS:528:DC%2BD3cXntFOmsLw%3D 10985868
45. C Sommer S Petrausch T Lindenlaub KV Toyka 1999 Neutralizing antibodies to interleukin 1-receptor reduce pain associated behavior in mice with experimental neuropathy Neuroscience Letters 270 1 25 28 1:CAS:528: DyaK1MXksFaitrs%3D 10454137
46. R Dominici M Cattaneo G Malferrari D Archi C Mariani LM Grimaldi, et al. 2002 Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha Immunogenetics 54 2 82 86 1:CAS:528:DC%2BD38Xjs1ahu7c%3D 12037600
47. J Hulkkonen P Laippala M Hurme 2000 A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals European Cytokine Network 11 2 251 255 1:CAS:528:DC%2BD3cXmt1Oht7w%3D 10903804
48. TL McDowell JA Symons R Ploski O Førre GW Duff 1995 A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism Arthritis and Rheumatism 38 2 221 228 1:STN:280: DyaK2M7ltFSmsg%3D%3D 7848312
49. F Pociot J Mølvig L Wogensen H Worsaae J Nerup 1992 A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro European Journal of Clinical Investigation 22 6 396 402 1:CAS:528:DyaK3sXitVKltA%3D%3D 1353022
50. FS di Giovine E Takhsh AI Blakemore GW Duff 1992 Single base polymorphism at -511 in the human interleukin-1 beta gene (IL1 beta) Human Molecular Genetics 1 6 450 1:CAS:528:DyaK38XmtVKhsrg%3D 1301918
51. JK Tarlow AI Blakemore A Lennard R Solari HN Hughes A Steinkasserer, et al. 1993 Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat Human Genetics 91 4 403 404 1:CAS:528:DyaK3sXlsFyjtro%3D 8500797
52. NA Tountas V Casini-Raggi H Yang FS di Giovine M Vecchi L Kam, et al. 1999 Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis Gastroenterology 117 4 806 813 1:CAS:528:DyaK1MXmvVWnur0%3D 10500062
53. S Solovieva P Leino-Arjas J Saarela K Luoma R Raininko H Riihimäki 2004 Possible association of interleukin 1 gene locus polymorphisms with low back pain Pain 109 1-2 8 19 1:CAS:528:DC%2BD2cXjtVCgur8%3D 15082121
54. H Bessler Y Shavit E Mayburd G Smirnov B Beilin 2006 Postoperative pain, morphine consumption, and genetic polymorphism of IL-1 beta and IL-1 receptor antagonist Neuroscience Letters 404 1-2 154 158 1:CAS:528:DC%2BD28XntFSit7o%3D 16777324
55. BA Winkelstein MD Rutkowski JN Weinstein JA DeLeo 2001 Quantification of neural tissue injury in a rat radiculopathy model: Comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons Journal of Neuroscience Methods 111 1 49 57 1:CAS:528:DC%2BD3MXntV2jurg%3D 11574119
56. M Bianchi R Maggi F Pimpinelli T Rubino D Parolaro V Poli, et al. 1999 Presence of a reduced opioid response in interleukin-6 knock out mice European Journal of Neuroscience 11 5 1501 1507 1:STN:280:DyaK1M3jtl2nsg%3D%3D 10215902
57. XS Wang Q Shi LA Williams CS Cleeland GM Mobley JM Reuben, et al. 2008 Serum interleukin-6 predicts the development of multiple symptoms at nadir of allogeneic hematopoietic stem cell transplantation Cancer 113 8 2102 2109 18792065
58. D Fishman G Faulds R Jeffery V Mohamed-Ali JS Yudkin S Humphries, et al. 1998 The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis Journal of Clinical Investigation 102 7 1369 1376 1:CAS:528:DyaK1cXmsFOrsrY%3D 9769329
59. CC Reyes-Gibby B El Osta MR Spitz H Parsons R Kurzrock X Wu, et al. 2008 The influence of tumor necrosis factor-alpha -308 G/A and IL-6-174 G/C on pain and analgesia response in lung cancer patients receiving supportive care Cancer Epidemiology, Biomarkers and Prevention 17 11 3262 3267 1:CAS:528: DC%2BD1cXhtlCkurzF 18990769
60. K Oen PN Malleson DA Cabral AM Rosenberg RE Petty P Nickerson, et al. 2005 Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis Rheumatology (Oxford) 44 9 1115 1121 1:CAS:528:DC%2BD2MXovVKrtb8%3D
61. J Karppinen I Daavittila N Noponen M Haapea S Taimela H Vanharanta, et al. 2008 Is the interleukin-6 haplotype a prognostic factor for sciatica? European Journal of Pain: Ejp 12 8 1018 1025 1:CAS:528:DC%2BD1cXhtV2jtLbI 18321738
62. E Utreras A Futatsugi P Rudrabhatla J Keller MJ Iadarola HC Pant, et al. 2009 Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35 The Journal of Biological Chemistry 284 4 2275 2284 1:CAS:528:DC%2BD1MXlvFejtg%3D%3D 19049962
63. G Segond von Banchet MK Boettger N Fischer M Gajda R Bräuer HG Schaible 2009 Experimental arthritis causes tumor necrosis factor-alpha- dependent infiltration of macrophages into rat dorsal root ganglia which correlates with pain-related behavior Pain 145 1-2 151 159 1:CAS:528: DC%2BD1MXhtVKntbfF 19560272
64. AG Wilson JA Symons TL McDowell HO McDevitt GW Duff 1997 Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation Proceedings of the National Academy of Sciences of the United States of America 94 7 3195 3199 1:CAS:528:DyaK2sXisVKgtbg%3D 9096369
65. SH Ahn YW Cho MW Ahn SH Jang YK Sohn HS Kim 2002 mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs Spine (Phila Pa 1976) 27 9 911 917
66. XM Wang M Hamza TX Wu RA Dionne 2009 Upregulation of IL-6, IL-8 and CCL2 gene expression after acute inflammation: Correlation to clinical pain Pain 142 3 275 283 1:CAS:528:DC%2BD1MXjtF2jsb8%3D 19233564
67. J Hull A Thomson D Kwiatkowski 2000 Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families Thorax 55 12 1023 1027 1:STN:280:DC%2BD3M7hs1aktg%3D%3D 11083887
68. CC Reyes-Gibby M Spitz X Wu K Merriman C Etzel E Bruera, et al. 2007 Cytokine genes and pain severity in lung cancer: Exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A Cancer Epidemiology, Biomarkers and Prevention 16 12 2745 2751 1:CAS:528:DC%2BD2sXhsVenur3E 18086782
69. AH Schinkel E Wagenaar L van Deemter CA Mol P Borst 1995 Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A Journal of Clinical Investigation 96 4 1698 1705 1:CAS:528:DyaK2MXosFyhsLY%3D 7560060
70. SJ Thompson K Koszdin CM Bernards 2000 Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein Anesthesiology 92 5 1392 1399 1:CAS:528:DC%2BD3cXjslSrs70%3D 10781286
71. M King W Su A Chang A Zuckerman GW Pasternak 2001 Transport of opioids from the brain to the periphery by P-glycoprotein: Peripheral actions of central drugs Nature Neuroscience 4 3 268 274 1:CAS:528:DC%2BD3MXhsF2rurg%3D 11224543
72. CF Higgins 2001 ABC transporters: Physiology, structure and mechanism-an overview Research in Microbiology 152 3-4 205 210 1:CAS:528:DC%2BD3MXks12jsrc%3D 11421269
73. S Hoffmeyer O Burk O von Richter HP Arnold J Brockmöller A Johne, et al. 2000 Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo Proceedings of the National Academy of Sciences of the United States of America 97 7 3473 3478 1:CAS:528:DC%2BD3cXitlWqtL8%3D 10716719
74. J Lötsch N von Hentig R Freynhagen N Griessinger M Zimmermann A Doehring, et al. 2009 Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers Pharmacogenetics and genomics 19 6 429 436 19514130
75. D Campa A Gioia A Tomei P Poli R Barale 2008 Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief Clinical Pharmacology and Therapeutics 83 4 559 566 1:CAS:528:DC%2BD1cXjsFClu7s%3D 17898703
76. JK Coller DT Barratt K Dahlen MH Loennechen AA Somogyi 2006 ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals Clinical Pharmacology and Therapeutics 80 6 682 690 1:CAS:528:DC%2BD28Xhtleisb7L 17178268
77. HJ Park HK Shinn SH Ryu HS Lee CS Park JH Kang 2007 Genetic polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans Clinical Pharmacology and Therapeutics 81 4 539 546 1:CAS:528:DC%2BD2sXkvFymu7g%3D 17192767
78. FP Guengerich 2008 Cytochrome p450 and chemical toxicology Chemical Research in Toxicology 21 1 70 83 1:CAS:528:DC%2BD2sXhtlynurbF 18052394
79. UM Stamer F Musshoff M Kobilay B Madea A Hoeft F Stuber 2007 Concentrations of tramadol and O-desmethyltramadol enantiomers in different CYP2D6 genotypes Clinical Pharmacology and Therapeutics 82 1 41 47 1:CAS:528:DC%2BD2sXotVGju7o%3D 17361124
80. UM Zanger K Klein T Saussele J Blievernicht MH Hofmann M Schwab 2007 Polymorphic CYP2B6: Molecular mechanisms and emerging clinical significance Pharmacogenomics 8 7 743 759 1:CAS:528:DC%2BD2sXnvVertrw%3D 17638512
81. WD Paar S Poche J Gerloff HJ Dengler 1997 Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol European Journal of Clinical Pharmacology 53 3-4 235 239 1:CAS:528:DyaK2sXnvVensLY%3D 9476037
82. J de Leon MT Susce E Murray-Carmichael 2006 The AmpliChip CYP450 genotyping test: Integrating a new clinical tool Molecular diagnosis & therapy 10 3 135 151
83. J Desmeules MP Gascon P Dayer M Magistris 1991 Impact of environmental and genetic factors on codeine analgesia European Journal of Clinical Pharmacology 41 1 23 26 1:CAS:528:DyaK3MXlsFSgs7g%3D 1782973
84. QY Yue J Hasselström JO Svensson J Säwe 1991 Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: Comparisons between extensive and poor hydroxylators of debrisoquine British Journal of Clinical Pharmacology 31 6 635 642 1:CAS:528:DyaK3MXks1eqtbg%3D 1867957
85. G Wang H Zhang F He X Fang 2006 Effect of the CYP2D6*10 C188T polymorphism on postoperative tramadol analgesia in a Chinese population European Journal of Clinical Pharmacology 62 11 927 931 1:CAS:528: DC%2BD28XhtFegtLfJ 16960721
86. S Crettol JJ Déglon J Besson M Croquette-Krokar R Hämmig I Gothuey, et al. 2006 ABCB1 and cytochrome P450 genotypes and phenotypes: Influence on methadone plasma levels and response to treatment Clinical Pharmacology and Therapeutics 80 6 668 681 1:CAS:528:DC%2BD28Xhtleisb7K 17178267
87. A Pilotto D Seripa M Franceschi C Scarcelli D Colaizzo E Grandone, et al. 2007 Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: Role of cytochrome P450 2C9 polymorphisms Gastroenterology 133 2 465 471 1:CAS:528:DC%2BD2sXhtVWqsr7K 17681167
88. SC Armstrong KL Cozza 2003 Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: Theory and clinical reality, part I Psychosomatics 44 2 167 171 12618536
89. M Holthe TN Rakvåg P Klepstad JR Idle S Kaasa HE Krokan, et al. 2003 Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: Identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients The Pharmacogenomics Journal 3 1 17 26 1:CAS:528:DC%2BD3sXhslyjtrk%3D 12629580
90. Y Duguay C Báár F Skorpen C Guillemette 2004 A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity Clinical Pharmacology and Therapeutics 75 3 223 233 1:CAS:528:DC%2BD2cXhslenurc%3D 15001974
91. DS Darbari RH van Schaik EV Capparelli S Rana R McCarter J van den Anker 2008 UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease American Journal of Hematology 83 3 200 202 1:CAS:528:DC%2BD1cXjsFylu7Y%3D 17724700
92. JS Mogil 2009 Are we getting anywhere in human pain genetics? Pain 146 3 231 232 19679395
93. TT Rakvåg P Klepstad C Báár TM Kvam O Dale S Kaasa, et al. 2005 The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients Pain 116 1-2 73 78 15927391
94. K Hagen E Pettersen LJ Stovner F Skorpen JA Zwart 2006 The association between headache and Val158Met polymorphism in the catechol-O-methyltransferase gene: The HUNT Study The Journal of Headache and Pain 7 2 70 74 1:CAS:528:DC%2BD28XksFCjsbg%3D 16688411 (Pubitemid 44419858)
95. G Vargas-Alarcón JM Fragoso D Cruz-Robles A Vargas A Vargas JI Lao-Villadóniga, et al. 2007 Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia Arthritis Research & Therapy 9 5 R110
96. H Kim H Lee J Rowan J Brahim RA Dionne 2006 Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans Molecular Pain 2 24 16848906
97. G Ruaño PD Thompson A Windemuth RL Seip A Dande A Sorokin, et al. 2007 Physiogenomic association of statin-related myalgia to serotonin receptors Muscle and Nerve 36 3 329 335 17600820
98. AL Guimarães F Correia-Silva Jde AR Sá JM Victória MG Diniz O Costa Fde, et al. 2007 Investigation of functional gene polymorphisms IL-1beta, IL-6, IL-10 and TNF-alpha in individuals with recurrent aphthous stomatitis Archives of Oral Biology 52 3 268 272 17052682
99. P Klepstad O Dale F Skorpen PC Borchgrevink S Kaasa 2005 Genetic variability and clinical efficacy of morphine Acta Anaesthesiologica Scandinavica 49 7 902 908 1:CAS:528:DC%2BD2MXpslSlu7w%3D 16045647
100. RS Pedersen P Damkier K Brosen 2005 Tramadol as a new probe for cytochrome P450 2D6 phenotyping: A population study Clinical Pharmacology and Therapeutics 77 6 458 467 1:CAS:528:DC%2BD2MXlt1GqtrY%3D 15961977
101. JK Coller C Joergensen DJ Foster H James D Gillis L Christrup, et al. 2007 Lack of influence of CYP2D6 genotype on the clearance of (R)-, (S)- and racemic-methadone International Journal of Clinical Pharmacology and Therapeutics 45 7 410 417 1:CAS:528:DC%2BD2sXpt1yqurg%3D 17725248
102. A Ferrari CP Coccia A Bertolini E Sternieri 2004 Methadone-metabolism, pharmacokinetics and interactions Pharmacological Research 50 6 551 559 1:CAS:528:DC%2BD2cXovVyqsr8%3D 15501692
103. MR Shiran MS Lennard MZ Iqbal O Lagundoye N Seivewright GT Tucker, et al. 2009 Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment British Journal of Clinical Pharmacology 67 1 29 37 1:CAS:528:DC%2BD1MXitFyqu78%3D 19133059
104. W Cai B Chen X Tao S Ling Y Zhang 2000 Correlation of genetic polymorphism of cytochrome P4502D6 with dextromethorphan oxidative metabolism in Chinese Zhonghua Yixue Yichuanxue Zazhi 17 3 181 184 1:CAS:528: DC%2BD3cXmvFWhtro%3D 10837520
105. T Takashima S Murase K Iwasaki K Shimada 2005 Evaluation of dextromethorphan metabolism using hepatocytes from CYP2D6 poor and extensive metabolizers Drug Metabolism and Pharmacokinetics 20 3 177 182 1:CAS:528:DC%2BD2MXoslGmtbg%3D 15988119