Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures

Neurobiology of Disease

Volumn 41, Issue 1, 2011, Pages 96-103

  Gibbons, Hannah M ^a   Smith, Amy M ^a   Teoh, H Heng ^b   Bergin, Peter M ^a,c   Mee, Edward W ^a,c   Faull, Richard L M ^a   Dragunow, Mike ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b Labtests   (New Zealand)

^c AUCKLAND CITY HOSPITAL   (New Zealand)

Author keywords

Apoptosis; Epilepsy; Microglia; Phagocytosis; Primary adult human cell culture; Valproic acid

Indexed keywords

CASPASE 3; CD45 ANTIGEN; TRANSCRIPTION FACTOR PU 1; VALPROIC ACID;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROGLIA; NERVE CELL LESION; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ADULT; ANTICONVULSANTS; ANTIGENS, CD45; APOPTOSIS; CASPASE 3; CELLS, CULTURED; HUMANS; MICROGLIA; PHAGOCYTOSIS; PROTO-ONCOGENE PROTEINS; TRANS-ACTIVATORS; VALPROIC ACID;

EID: 78349306562     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.08.024     Document Type: Article

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