Anti-allodynic effect of the flavonoid myricetin in a rat model of neuropathic pain: Involvement of p38 and protein kinase C mediated modulation of Ca2+ channels

European Journal of Pain

Volumn 14, Issue 10, 2010, Pages 992-998

  Hagenacker, Tim ^a   Hillebrand, Imke ^a   Wissmann, Andreas ^a   Büsselberg, Dietrich ^b   Schäfers, Maria ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b WEILL CORNELL MEDICAL COLLEGE   (Qatar)

Author keywords

Flavonoids; Myricetin; Neuropathic pain; Patch clamp; Voltage activated calcium channel currents

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHELERYTHRINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYRICETIN; PROTEIN KINASE C; VOLTAGE GATED CALCIUM CHANNEL;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; DEPOLARIZATION; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HYPERALGESIA; MALE; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SPINAL GANGLION; SPINAL NERVE;

ANALGESICS, NON-NARCOTIC; ANIMALS; BEHAVIOR, ANIMAL; CALCIUM CHANNELS; ELECTROPHYSIOLOGY; FLAVONOIDS; GANGLIA, SPINAL; HOT TEMPERATURE; LIGATION; MALE; NEURALGIA; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PATCH-CLAMP TECHNIQUES; PHYSICAL STIMULATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, WISTAR; SPINAL NERVES;

EID: 78349305945     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2010.04.005     Document Type: Article

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