The mitogen-activated protein kinase p38-2 is necessary for the inhibition of N-type calcium current by bradykinin

Journal of Neuroscience

Volumn 18, Issue 1, 1998, Pages 112-118

  Wilk Blaszczak, Malgorzata A ^a   Stein, Bernd ^b   Xu, Shuichan ^c   Barbosa, Miguel S ^c   Cobb, Melanie H ^c   Belardetti, Francesco ^c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b CELGENE CORPORATION   (United States)

^c NONE

Author keywords

Bradykinin; Calcium channels; G protein; G13; MAPK; Neuroblastoma x glioma; NG108 15; p38

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BRADYKININ; CALCIUM CHANNEL; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0031963773     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-01-00112.1998     Document Type: Article

References (5)

1. Ahn NG, Robbins DJ, Haycock JW, Seger R, Cobb MH, Krebs EG (1992) Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin. J Neurochem 59:147-156.
2. Beyaert R, Cuenda A, Berghe WV, Plaisance S, Lee JC, Haegeman G, Cohen P, Fiers W (1996) The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumour necrosis factor. EM BO J. 15:1914-1923.
3. Bourne HR, Sanders DA, McCormick F (1990) The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348:125-132.
4. Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349:117-127.
5. Brown DA, Higashida H (1988a) Membrane current responses of NG108-15 mouse neuroblastoma x rat glioma hybrid cells to bradykinin. J Physiol (Lond) 397:167-184.