Protein kinase C isoforms differentially phosphorylate Cav1.2 α1c (Biochemistry (2009) 48, (6674) DOI: 10.1021/bi900322a);Protein kinase C isoforms differentially phosphorylate Cav1.2 α1c

Biochemistry

Volumn 48, Issue 28, 2009, Pages 6674-6683

  Yang, Lin ^a   Doshi, Darshan ^a   Morrow, John ^a   Katchman, Alexander ^a   Chen, Xiang ^a   Marx, Steven O ^a,b  

^a Columbia University ^*  (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; EPITOPES;

BIOCHEMICAL INFORMATION; BISINDOLYLMALEIMIDE; CARDIAC CONTRACTILITY; EPITOPE SPECIFIC ANTIBODIES; MOLECULAR MECHANISM; PHOSPHORYLATION SITES; PROTEIN PHOSPHORYLATION; SYMPATHETIC NERVOUS SYSTEMS;

PHOSPHORYLATION;

BISINDOLYLMALEIMIDE; CALCIUM CHANNEL L TYPE; EPITOPE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA; PROTEIN KINASE C GAMMA; PROTEIN KINASE C THETA; PROTEIN KINASE C ZETA; SERINE;

ADRENERGIC SYSTEM; ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; ISOLATED HEART; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

RATTUS;

EID: 67650474249     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9013903     Document Type: Erratum

References (42)

1. Fabiato, A., and Fabiato, F. (1979) Calcium and cardiac excitation-contraction coupling. Annu. Rev. Physiol. 41, 473-484.
2. Kamp, T. J., and Hell, J. W. (2000) Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ. Res. 87, 1095-1102.
3. Dempsey, E. C., Newton, A. C., Mochly-Rosen, D., Fields, A. P., Reyland, M. E., Insel, P. A., and Messing, R. O. (2000) Protein kinase Cisozymes and the regulation of diverse cell responses. Am. J. Physiol. 279, L429-L438.
4. Dorn, G. W.II, Tepe, N. M., Lorenz, J. N., Koch, W. J., and Liggett, S. B. (1999) Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gαq-overexpressing mice. Proc. Natl. Acad. Sci. U.S.A. 96, 6400-6405.
5. Dorn, G. W.II, and Force, T. (2005) Protein kinase cascades in the regulation of cardiac hypertrophy. J. Clin. Invest. 115, 527-537.
6. Puceat, M., Hilal-Dandan, R., Strulovici, B., Brunton, L. L., and Brown, J. H. (1994) Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes. J. Biol. Chem. 269, 16938-16944.
7. 2+- and protein kinase C-dependent mechanism. Am. J. Physiol. 280, H1528-H1536.
8. Robu, V. G., Pfeiffer, E. S., Robia, S. L., Balijepalli, R. C., Pi, Y., Kamp, T. J., and Walker, J. W. (2003) Localization of functional endothelin receptor signaling complexes in cardiac transverse tubules. J. Biol. Chem. 278, 48154-48161.
9. 2+ current by activation of protein kinase C in rat ventricular myocytes. J. Physiol. 524 (Part 3), 807-820.
10. Cheng, T. H., Chang, C. Y., Wei, J., and Lin, C. I. (1995) Effects of endothelin 1 on calcium and sodium currents in isolated human cardiac myocytes. Can. J. Physiol. Pharmacol. 73, 1774-1783.
11. 2+ current in guinea-pig ventricular myocytes. J. Physiol. 503 (Part 1), 55-65.
12. 2+ channel. Circ. Res. 102, 1378-1388.
13. Dosemeci, A., Dhallan, R. S., Cohen, N. M., Lederer, W. J., and Rogers, T. B. (1988) Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circ. Res. 62, 347-357.
14. 2+ channels. Nature 335, 249-251.
15. Tseng, G. N., and Boyden, P. A. (1991) Different effects of intracellular Ca and protein kinase C on cardiac T and L Ca currents. Am. J. Physiol. 261, H364-H379.
16. 2+ current: Independent of protein kinase C activation. Am. J. Physiol. 270, C655-C662.
17. 2+ channels. Circ. Res. 80, 720-729.
18. Nishikawa, K., Toker, A., Johannes, F. J., Songyang, Z., and Cantley, L. C. (1997) Determination of the specific substrate sequence motifs of protein kinase C isozymes. J. Biol. Chem. 272, 952-960.
19. Puri, T. S., Gerhardstein, B. L., Zhao, X. L., Ladner, M. B., and Hosey, M. M. (1997) Differential effects of subunit interactions on protein kinase A- and C-mediated phosphorylation of L-type calcium channels. Biochemistry 36, 9605-9615. (Pubitemid 27347002)
20. 2+ channel expression by deletions at the amino terminus of the cardiac α 1C subunit. Recept. Channels 4, 205-215.
21. 2+ channel and its modulation by protein kinase C. J. Biol. Chem. 273, 17901-17909.
22. McHugh, D., Sharp, E. M., Scheuer, T., and Catterall, W. A. (2000) Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain. Proc. Natl. Acad. Sci. U.S.A. 97, 12334-12338.
23. Yang, L., Liu, G., Zakharov, S. I., Morrow, J. P., Rybin, V. O., Steinberg, S. F., and Marx, S. O. (2005) Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms. J. Biol. Chem. 280, 207-214.
24. Yang, L., Liu, G., Zakharov, S. I., Bellinger, A. M., Mongillo, M., and Marx, S. O. (2007) Protein kinase G phosphorylates Cav1.2 α1c and β2 subunits. Circ. Res. 101, 465-474.
25. Braz, J. C., Gregory, K., Pathak, A., Zhao, W., Sahin, B., Klevitsky, R., Kimball, T. F., Lorenz, J. N., Nairn, A. C., Liggett, S. B., Bodi, I., Wang, S., Schwartz, A., Lakatta, E. G., DePaoli-Roach, A. A., Robbins, J., Hewett, T. E., Bibb, J. A., Westfall, M. V., Kranias, E. G., and Molkentin, J. D. (2004) PKC-α regulates cardiac contractility and propensity toward heart failure. Nat. Med. 10, 248-254.
26. Dobransky, T., Doherty-Kirby, A., Kim, A. R., Brewer, D., Lajoie, G., and Rylett, R. J. (2004) Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity. J. Biol. Chem. 279, 52059-52068.
27. Toni, L., Andrea, W., Johannes, C. C., Anne, B., Dominik, B., Peter, L., Franz, H., and Sven, M. (2008) Unchanged β-adrenergic stimulation of cardlac L-type calcium channels in Cav1.2 phosphorylation site S1928A mutant mice. J. Biol. Chem. 283, 35738-134744
28. Hall, D. D., Davare, M. A., Shi, M., Allen, M. L., Weisenhaus, M., McKnight, G. S., and Hell, J. W. (2007) Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry 46, 1635-1646. (Pubitemid 46256761)
29. Hulme, J. T., Westenbroek, R. E., Scheuer, T., and Catterall, W. A. (2006) Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during β1-adrenergic regulation. Proc. Natl. Acad. Sci. U.S.A. 103, 16574-16579.
30. Bunemann, M., Gerhardstein, B. L., Gao, T., and Hosey, M. M. (1999) Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the β2 subunit. J. Biol. Chem. 274, 33851-33854. (Pubitemid 129511708)
31. De Jongh, K. S., Murphy, B. J., Colvin, A. A., Hell, J. W., Takahashi, M., and Catterall, W. A. (1996) Specific phosphorylation of a site in the full-length form of the α1 subunit of the cardiac L-type calcium channel by adenosine 3′,5′-cyclic monophosphate-dependent protein kinase. Biochemistry 35, 10392-10402. (Pubitemid 26277298)
32. Jalili, T., Takeishi, Y., Song, G., Ball, N. A., Howles, G., and Walsh, R. A. (1999) PKC translocation without changes in GRq and PLC-β protein abundance in cardiac hypertrophy and failure. Am. J. Physiol. 277, H2298-H2304.
33. Takeishi, Y., Jalili, T., Ball, N. A., and Walsh, R. A. (1999) Responses of cardiac protein kinase C isoforms to distinct pathological stimuli are differentially regulated. Circ. Res. 85, 264-271.
34. Bayer, A. L., Heidkamp, M. C., Patel, N., Porter, M., Engman, S., and Samarel, A. M. (2003) Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy. Mol. Cell. Biochem. 242, 145-152.
35. Murphy, S., and Frishman, W. H. (2005) Protein kinase C in cardiac disease and as a potential therapeutic target. Cardiol. Rev. 13, 3-12.
36. Wakasaki, H., Koya, D., Schoen, F. J., Jirousek, M. R., Ways, D. K., Hoit, B. D., Walsh, R. A., and King, G. L. (1997) Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy. Proc. Natl. Acad. Sci. U.S.A. 94, 9320-9325.
37. Takeishi, Y., Ping, P., Bolli, R., Kirkpatrick, D. L., Hoit, B. D., and Walsh, R. A. (2000) Transgenic overexpression of constitutively active protein kinase Cε causes concentric cardiac hypertrophy. Circ. Res. 86, 1218-1223.
38. 2+ signals for facilitation. J. Cell Biol. 171, 537-547.
39. 2+ channel facilitation mediated by phosphorylation of the β subunit by CaMKII. Mol. Cell 23, 641-650.
40. 2+ channels. Annu. Rev. Cell Dev. Biol. 16, 521-555.
41. Jiang, L. H., Gawler, D. J., Hodson, N., Milligan, C. J., Pearson, H. A., Porter, V., and Wray, D. (2000) Regulation of cloned cardiac L-type calcium channels by cGMP-dependent protein kinase. J. Biol. Chem. 275, 6135-6143.
42. Hell, J. W., Yokoyama, C. T., Breeze, L. J., Chavkin, C., and Catterall, W. A. (1995) Phosphorylation of presynaptic and postsy-naptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons. EMBO J. 14, 3036-3044.