-
1
-
-
58449131001
-
Chemical and molecular basis of the carcinogenicity of Aristolochia plants
-
8
-
Schmeiser HH, Stiborova M, Arlt VM,. Chemical and molecular basis of the carcinogenicity of Aristolochia plants. Curr Opin Drug Dis Develop 2009; 12: 141 8.
-
(2009)
Curr Opin Drug Dis Develop
, vol.12
, pp. 141
-
-
Schmeiser, H.H.1
Stiborova, M.2
Arlt, V.M.3
-
3
-
-
0034622082
-
Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)
-
92
-
Nortier JL, Martinez MC, Schmeiser HH, Arlt VM, Bieler CA, Petein M, Depierreux MF, de Pauw L, Abramowicz D, Vereerstraeten P, Vanherweghem JL,. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). New Engl J Med 2000; 342: 1686 92.
-
(2000)
New Engl J Med
, vol.342
, pp. 1686
-
-
Nortier, J.L.1
Martinez, M.C.2
Schmeiser, H.H.3
Arlt, V.M.4
Bieler, C.A.5
Petein, M.6
Depierreux, M.F.7
De Pauw, L.8
Abramowicz, D.9
Vereerstraeten, P.10
Vanherweghem, J.L.11
-
4
-
-
39449104221
-
Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: A case series with 15-year follow-up
-
7
-
Lemy A, Wissing KM, Rorive S, Zlotta A, Roumeguere T, Muniz Martinez MC, Decaestecker C, Salmon I, Abramowicz D, Vanherweghem JL, Nortier J,. Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: a case series with 15-year follow-up. Am J Kidney Dis 2008; 51: 471 7.
-
(2008)
Am J Kidney Dis
, vol.51
, pp. 471
-
-
Lemy, A.1
Wissing, K.M.2
Rorive, S.3
Zlotta, A.4
Roumeguere, T.5
Muniz Martinez, M.C.6
Decaestecker, C.7
Salmon, I.8
Abramowicz, D.9
Vanherweghem, J.L.10
Nortier, J.11
-
5
-
-
0029983768
-
Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy
-
8
-
Schmeiser HH, Bieler CA, Wiessler M, van Ypersele de Strihou C, Cosyns JP,. Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy. Cancer Res 1996; 56: 2025 8.
-
(1996)
Cancer Res
, vol.56
, pp. 2025
-
-
Schmeiser, H.H.1
Bieler, C.A.2
Wiessler, M.3
Van Ypersele De Strihou, C.4
Cosyns, J.P.5
-
6
-
-
0031284662
-
32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy
-
7
-
Bieler CA, Stiborova M, Wiessler M, Cosyns JP, van Ypersele de Strihou C, Schmeiser HH,. 32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy. Carcinogenesis 1997; 18: 1063 7.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1063
-
-
Bieler, C.A.1
Stiborova, M.2
Wiessler, M.3
Cosyns, J.P.4
Van Ypersele De Strihou, C.5
Schmeiser, H.H.6
-
7
-
-
0035802716
-
Urothelial malignant disease and Chinese herbal nephropathy
-
6
-
Lord GM, Cook T, Arlt VM, Schmeiser HH, Williams G, Pusey CD,. Urothelial malignant disease and Chinese herbal nephropathy. Lancet 2001; 358: 1515 6.
-
(2001)
Lancet
, vol.358
, pp. 1515
-
-
Lord, G.M.1
Cook, T.2
Arlt, V.M.3
Schmeiser, H.H.4
Williams, G.5
Pusey, C.D.6
-
8
-
-
4143142193
-
Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer
-
80
-
Arlt VM, Alunni-Perret V, Quatrehomme G, Ohayon P, Albano L, Gaid H, Michiels JF, Meyrier A, Cassuto E, Wiessler M, Schmeiser HH, Cosyns JP,. Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer. Int J Cancer 2004; 111: 977 80.
-
(2004)
Int J Cancer
, vol.111
, pp. 977
-
-
Arlt, V.M.1
Alunni-Perret, V.2
Quatrehomme, G.3
Ohayon, P.4
Albano, L.5
Gaid, H.6
Michiels, J.F.7
Meyrier, A.8
Cassuto, E.9
Wiessler, M.10
Schmeiser, H.H.11
Cosyns, J.P.12
-
9
-
-
20144364600
-
Detection of Herba Aristolochia Mollissemae in a patient with unexplained nephropathy
-
10
-
Lo SH, Wong KS, Arlt VM, Phillips DH, Lai CK, Poon WT, Chan CK, Mo KL, Chan KW, Chan A,. Detection of Herba Aristolochia Mollissemae in a patient with unexplained nephropathy. Am J Kidney Dis 2005; 45: 407 10.
-
(2005)
Am J Kidney Dis
, vol.45
, pp. 407
-
-
Lo, S.H.1
Wong, K.S.2
Arlt, V.M.3
Phillips, D.H.4
Lai, C.K.5
Poon, W.T.6
Chan, C.K.7
Mo, K.L.8
Chan, K.W.9
Chan, A.10
-
10
-
-
0141905769
-
Aristolochic acid, an herbal carcinogen, sold on the Web after FDA alert
-
7
-
Gold LS, Slone TH,. Aristolochic acid, an herbal carcinogen, sold on the Web after FDA alert. New Engl J Med 2003; 349: 1576 7.
-
(2003)
New Engl J Med
, vol.349
, pp. 1576
-
-
Gold, L.S.1
Slone, T.H.2
-
11
-
-
34547549854
-
Aristolochic acid and the etiology of endemic (Balkan) nephropathy
-
34
-
Grollman AP, Shibutani S, Moriya M, Miller F, Wu L, Moll U, Suzuki N, Fernandes A, Rosenquist T, Medverec Z, Jakovina K, Brdar B, et al. Aristolochic acid and the etiology of endemic (Balkan) nephropathy. Proc Natl Acad Sci USA 2007; 104: 12129 34.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12129
-
-
Grollman, A.P.1
Shibutani, S.2
Moriya, M.3
Miller, F.4
Wu, L.5
Moll, U.6
Suzuki, N.7
Fernandes, A.8
Rosenquist, T.9
Medverec, Z.10
Jakovina, K.11
Brdar, B.12
-
12
-
-
36148933380
-
Aristolochic acid mutagenesis: Molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer
-
61
-
Arlt VM, Stiborova M, vom Brocke J, Simoes ML, Lord GM, Nortier JL, Hollstein M, Phillips DH, Schmeiser HH,. Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer. Carcinogenesis 2007; 28: 2253 61.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2253
-
-
Arlt, V.M.1
Stiborova, M.2
Vom Brocke, J.3
Simoes, M.L.4
Lord, G.M.5
Nortier, J.L.6
Hollstein, M.7
Phillips, D.H.8
Schmeiser, H.H.9
-
13
-
-
0028237221
-
Chinese herbs nephropathy: A clue to Balkan endemic nephropathy?
-
8
-
Cosyns JP, Jadoul M, Squifflet JP, de Plaen JF, Ferluga D, van Ypersele de Strihou C,. Chinese herbs nephropathy: a clue to Balkan endemic nephropathy? Kidney Int 1994; 45: 1680 8.
-
(1994)
Kidney Int
, vol.45
, pp. 1680
-
-
Cosyns, J.P.1
Jadoul, M.2
Squifflet, J.P.3
De Plaen, J.F.4
Ferluga, D.5
Van Ypersele De Strihou, C.6
-
14
-
-
0037057532
-
Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?
-
2
-
Arlt VM, Ferluga D, Stiborova M, Pfohl-Leszkowicz A, Vukelic M, Ceovic S, Schmeiser HH, Cosyns JP,. Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer? Int J Cancer 2002; 101: 500 2.
-
(2002)
Int J Cancer
, vol.101
, pp. 500
-
-
Arlt, V.M.1
Ferluga, D.2
Stiborova, M.3
Pfohl-Leszkowicz, A.4
Vukelic, M.5
Ceovic, S.6
Schmeiser, H.H.7
Cosyns, J.P.8
-
15
-
-
2942513154
-
DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy
-
7
-
Lord GM, Hollstein M, Arlt VM, Roufosse C, Pusey CD, Cook T, Schmeiser HH,. DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy. Am J Kidney Dis 2004; 43: e11 7.
-
(2004)
Am J Kidney Dis
, vol.43
, pp. 11
-
-
Lord, G.M.1
Hollstein, M.2
Arlt, V.M.3
Roufosse, C.4
Pusey, C.D.5
Cook, T.6
Schmeiser, H.H.7
-
16
-
-
0035138584
-
Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR
-
40
-
Arlt VM, Schmeiser HH, Pfeifer GP,. Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR. Carcinogenesis 2001; 22: 133 40.
-
(2001)
Carcinogenesis
, vol.22
, pp. 133
-
-
Arlt, V.M.1
Schmeiser, H.H.2
Pfeifer, G.P.3
-
17
-
-
1542327685
-
Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene
-
8
-
Liu Z, Hergenhahn M, Schmeiser HH, Wogan GN, Hong A, Hollstein M,. Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene. Proc Natl Acad Sci USA 2004; 101: 2963 8.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2963
-
-
Liu, Z.1
Hergenhahn, M.2
Schmeiser, H.H.3
Wogan, G.N.4
Hong, A.5
Hollstein, M.6
-
18
-
-
58149459327
-
TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours
-
90
-
Nedelko T, Arlt VM, Phillips DH, Hollstein M,. TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours. Int J Cancer 2009; 124: 987 90.
-
(2009)
Int J Cancer
, vol.124
, pp. 987
-
-
Nedelko, T.1
Arlt, V.M.2
Phillips, D.H.3
Hollstein, M.4
-
19
-
-
34249277438
-
Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis
-
68
-
Stemmer K, Ellinger-Ziegelbauer H, Ahr HJ, Dietrich DR,. Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis. Cancer Res 2007; 67: 4052 68.
-
(2007)
Cancer Res
, vol.67
, pp. 4052
-
-
Stemmer, K.1
Ellinger-Ziegelbauer, H.2
Ahr, H.J.3
Dietrich, D.R.4
-
20
-
-
33947317378
-
Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (Kidney) and non-target (Liver) tissues in rats
-
Chen T, Guo L, Zhang L, Shi L, Fang H, Sun Y, Fuscoe JC, Mei N,. Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (Kidney) and non-target (Liver) tissues in rats. BMC Bioinform 2006; 7 (Suppl 2): S20.
-
(2006)
BMC Bioinform
, vol.7
, Issue.SUPPL. 2
, pp. 20
-
-
Chen, T.1
Guo, L.2
Zhang, L.3
Shi, L.4
Fang, H.5
Sun, Y.6
Fuscoe, J.C.7
Mei, N.8
-
21
-
-
51549086000
-
Gene expression profiles modulated by the human carcinogen aristolochic acid i in human cancer cells and their dependence on TP53
-
98
-
Simoes ML, Hockley SL, Schwerdtle T, da Costa GG, Schmeiser HH, Phillips DH, Arlt VM,. Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53. Toxicol Appl Pharmacol 2008; 232: 86 98.
-
(2008)
Toxicol Appl Pharmacol
, vol.232
, pp. 86
-
-
Simoes, M.L.1
Hockley, S.L.2
Schwerdtle, T.3
Da Costa, G.G.4
Schmeiser, H.H.5
Phillips, D.H.6
Arlt, V.M.7
-
22
-
-
0023923240
-
Tumour induction in mice following exposure to aristolochic acid
-
5
-
Mengs U,. Tumour induction in mice following exposure to aristolochic acid. Arch Toxicol 1988; 61: 504 5.
-
(1988)
Arch Toxicol
, vol.61
, pp. 504
-
-
Mengs, U.1
-
23
-
-
39149106168
-
The 32P-postlabeling assay for DNA adducts
-
81
-
Phillips DH, Arlt VM,. The 32P-postlabeling assay for DNA adducts. Nat Protoc 2007; 2: 2772 81.
-
(2007)
Nat Protoc
, vol.2
, pp. 2772
-
-
Phillips, D.H.1
Arlt, V.M.2
-
24
-
-
33750595636
-
Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2
-
Hockley SL, Arlt VM, Brewer D, Giddings I, Phillips DH,. Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2. BMC Genomics 2006; 7: 260.
-
(2006)
BMC Genomics
, vol.7
, pp. 260
-
-
Hockley, S.L.1
Arlt, V.M.2
Brewer, D.3
Giddings, I.4
Phillips, D.H.5
-
25
-
-
38849094467
-
Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53
-
10
-
Hockley SL, Arlt VM, Jahnke G, Hartwig A, Giddings I, Phillips DH,. Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53. Carcinogenesis 2008; 29: 202 10.
-
(2008)
Carcinogenesis
, vol.29
, pp. 202
-
-
Hockley, S.L.1
Arlt, V.M.2
Jahnke, G.3
Hartwig, A.4
Giddings, I.5
Phillips, D.H.6
-
26
-
-
0026542525
-
Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics
-
68
-
Forrester LM, Henderson CJ, Glancey MJ, Back DJ, Park BK, Ball SE, Kitteringham NR, McLaren AW, Miles JS, Skett P, et al. Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics. Biochem J 1992; 281: 359 68.
-
(1992)
Biochem J
, vol.281
, pp. 359
-
-
Forrester, L.M.1
Henderson, C.J.2
Glancey, M.J.3
Back, D.J.4
Park, B.K.5
Ball, S.E.6
Kitteringham, N.R.7
McLaren, A.W.8
Miles, J.S.9
Skett, P.10
-
27
-
-
71049164157
-
Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells
-
44
-
Kim S, Dere E, Burgoon LD, Chang CC, Zacharewski TR,. Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells. Toxicol Sci 2009; 112: 229 44.
-
(2009)
Toxicol Sci
, vol.112
, pp. 229
-
-
Kim, S.1
Dere, E.2
Burgoon, L.D.3
Chang, C.C.4
Zacharewski, T.R.5
-
28
-
-
58149139730
-
The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences
-
23
-
vom Brocke J, Krais A, Whibley C, Hollstein MC, Schmeiser HH,. The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences. Mutagenesis 2009; 24: 17 23.
-
(2009)
Mutagenesis
, vol.24
, pp. 17
-
-
Vom Brocke, J.1
Krais, A.2
Whibley, C.3
Hollstein, M.C.4
Schmeiser, H.H.5
-
29
-
-
0033011129
-
Urothelial lesions in Chinese-herb nephropathy
-
7
-
Cosyns JP, Jadoul M, Squifflet JP, Wese FX, van Ypersele de Strihou C,. Urothelial lesions in Chinese-herb nephropathy. Am J Kidney Dis 1999; 33: 1011 7.
-
(1999)
Am J Kidney Dis
, vol.33
, pp. 1011
-
-
Cosyns, J.P.1
Jadoul, M.2
Squifflet, J.P.3
Wese, F.X.4
Van Ypersele De Strihou, C.5
-
30
-
-
38649109829
-
Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy
-
67
-
Stiborova M, Frei E, Arlt VM, Schmeiser HH,. Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy. Mutat Res 2008; 658: 55 67.
-
(2008)
Mutat Res
, vol.658
, pp. 55
-
-
Stiborova, M.1
Frei, E.2
Arlt, V.M.3
Schmeiser, H.H.4
-
31
-
-
0035905749
-
Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: A new biomedical research tool
-
8
-
Luo JL, Yang Q, Tong WM, Hergenhahn M, Wang ZQ, Hollstein M,. Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool. Oncogene 2001; 20: 320 8.
-
(2001)
Oncogene
, vol.20
, pp. 320
-
-
Luo, J.L.1
Yang, Q.2
Tong, W.M.3
Hergenhahn, M.4
Wang, Z.Q.5
Hollstein, M.6
-
32
-
-
27144459404
-
Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53
-
34
-
Jaworski M, Hailfinger S, Buchmann A, Hergenhahn M, Hollstein M, Ittrich C, Schwarz M,. Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53. Carcinogenesis 2005; 26: 1829 34.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1829
-
-
Jaworski, M.1
Hailfinger, S.2
Buchmann, A.3
Hergenhahn, M.4
Hollstein, M.5
Ittrich, C.6
Schwarz, M.7
-
33
-
-
33748170994
-
Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences
-
8
-
Feldmeyer N, Schmeiser HH, Muehlbauer KR, Belharazem D, Knyazev Y, Nedelko T, Hollstein M,. Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences. Mutat Res 2006; 608: 163 8.
-
(2006)
Mutat Res
, vol.608
, pp. 163
-
-
Feldmeyer, N.1
Schmeiser, H.H.2
Muehlbauer, K.R.3
Belharazem, D.4
Knyazev, Y.5
Nedelko, T.6
Hollstein, M.7
-
34
-
-
0024989974
-
Aristolochic acid activates ras genes in rat tumors at deoxyadenosine residues
-
9
-
Schmeiser HH, Janssen JW, Lyons J, Scherf HR, Pfau W, Buchmann A, Bartram CR, Wiessler M,. Aristolochic acid activates ras genes in rat tumors at deoxyadenosine residues. Cancer Res 1990; 50: 5464 9.
-
(1990)
Cancer Res
, vol.50
, pp. 5464
-
-
Schmeiser, H.H.1
Janssen, J.W.2
Lyons, J.3
Scherf, H.R.4
Pfau, W.5
Buchmann, A.6
Bartram, C.R.7
Wiessler, M.8
-
35
-
-
0025916249
-
Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice
-
43
-
Schmeiser HH, Scherf HR, Wiessler M,. Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice. Cancer Lett 1991; 59: 139 43.
-
(1991)
Cancer Lett
, vol.59
, pp. 139
-
-
Schmeiser, H.H.1
Scherf, H.R.2
Wiessler, M.3
-
36
-
-
0034791132
-
Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells
-
42
-
Lebeau C, Arlt VM, Schmeiser HH, Boom A, Verroust PJ, Devuyst O, Beauwens R,. Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells. Kidney Int 2001; 60: 1332 42.
-
(2001)
Kidney Int
, vol.60
, pp. 1332
-
-
Lebeau, C.1
Arlt, V.M.2
Schmeiser, H.H.3
Boom, A.4
Verroust, P.J.5
Devuyst, O.6
Beauwens, R.7
-
37
-
-
27644597566
-
Early proximal tubule injury in experimental aristolochic acid nephropathy: Functional and histological studies
-
32
-
Lebeau C, Debelle FD, Arlt VM, Pozdzik A, de Prez EG, Phillips DH, Deschodt-Lanckman MM, Vanherweghem JL, Nortier JL,. Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies. Nephrol Dial Transplant 2005; 20: 2321 32.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 2321
-
-
Lebeau, C.1
Debelle, F.D.2
Arlt, V.M.3
Pozdzik, A.4
De Prez, E.G.5
Phillips, D.H.6
Deschodt-Lanckman, M.M.7
Vanherweghem, J.L.8
Nortier, J.L.9
-
38
-
-
69449105950
-
Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy
-
9
-
Bakhiya N, Arlt VM, Bahn A, Burckhardt G, Phillips DH, Glatt H,. Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. Toxicology 2009; 264: 74 9.
-
(2009)
Toxicology
, vol.264
, pp. 74
-
-
Bakhiya, N.1
Arlt, V.M.2
Bahn, A.3
Burckhardt, G.4
Phillips, D.H.5
Glatt, H.6
-
39
-
-
3943071150
-
Cytochrome C-mediated apoptosis
-
106
-
Jiang X, Wang X,. Cytochrome C-mediated apoptosis. Annu Rev Biochem 2004; 73: 87 106.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 87
-
-
Jiang, X.1
Wang, X.2
-
40
-
-
39349086390
-
Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation
-
607
-
Pozdzik AA, Salmon IJ, Debelle FD, Decaestecker C, van den Branden C, Verbeelen D, Deschodt-Lanckman MM, Vanherweghem JL, Nortier JL,. Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation. Kidney Int 2008; 73: 595 607.
-
(2008)
Kidney Int
, vol.73
, pp. 595
-
-
Pozdzik, A.A.1
Salmon, I.J.2
Debelle, F.D.3
Decaestecker, C.4
Van Den Branden, C.5
Verbeelen, D.6
Deschodt-Lanckman, M.M.7
Vanherweghem, J.L.8
Nortier, J.L.9
-
41
-
-
20444474590
-
Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53
-
43
-
Krones-Herzig A, Mittal S, Yule K, Liang H, English C, Urcis R, Soni T, Adamson ED, Mercola D,. Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53. Cancer Res 2005; 65: 5133 43.
-
(2005)
Cancer Res
, vol.65
, pp. 5133
-
-
Krones-Herzig, A.1
Mittal, S.2
Yule, K.3
Liang, H.4
English, C.5
Urcis, R.6
Soni, T.7
Adamson, E.D.8
Mercola, D.9
-
42
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
74
-
el-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Burrell M, Hill DE, Wang Y, et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 1994; 54: 1169 74.
-
(1994)
Cancer Res
, vol.54
, pp. 1169
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
-
43
-
-
3142679562
-
The negative role of cyclin G in ATM-dependent p53 activation
-
8
-
Ohtsuka T, Jensen MR, Kim HG, Kim KT, Lee SW,. The negative role of cyclin G in ATM-dependent p53 activation. Oncogene 2004; 23: 5405 8.
-
(2004)
Oncogene
, vol.23
, pp. 5405
-
-
Ohtsuka, T.1
Jensen, M.R.2
Kim, H.G.3
Kim, K.T.4
Lee, S.W.5
-
44
-
-
20244375365
-
UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin
-
63
-
Luo JL, Tong WM, Yoon JH, Hergenhahn M, Koomagi R, Yang Q, Galendo D, Pfeifer GP, Wang ZQ, Hollstein M,. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin. Cancer Res 2001; 61: 8158 63.
-
(2001)
Cancer Res
, vol.61
, pp. 8158
-
-
Luo, J.L.1
Tong, W.M.2
Yoon, J.H.3
Hergenhahn, M.4
Koomagi, R.5
Yang, Q.6
Galendo, D.7
Pfeifer, G.P.8
Wang, Z.Q.9
Hollstein, M.10
-
45
-
-
48749088588
-
Patterns of interstitial inflammation during the evolution of renal injury in experimental aristolochic acid nephropathy
-
91
-
Pozdzik AA, Salmon IJ, Husson CP, Decaestecker C, Rogier E, Bourgeade MF, Deschodt-Lanckman MM, Vanherweghem JL, Nortier JL,. Patterns of interstitial inflammation during the evolution of renal injury in experimental aristolochic acid nephropathy. Nephrol Dial Transplant 2008; 23: 2480 91.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 2480
-
-
Pozdzik, A.A.1
Salmon, I.J.2
Husson, C.P.3
Decaestecker, C.4
Rogier, E.5
Bourgeade, M.F.6
Deschodt-Lanckman, M.M.7
Vanherweghem, J.L.8
Nortier, J.L.9
-
46
-
-
62549127264
-
NF-kappaB pathways in the immune system: Control of the germinal center reaction
-
47
-
Goetz CA, Baldwin AS,. NF-kappaB pathways in the immune system: control of the germinal center reaction. Immunol Res 2008; 41: 233 47.
-
(2008)
Immunol Res
, vol.41
, pp. 233
-
-
Goetz, C.A.1
Baldwin, A.S.2
-
47
-
-
33750214678
-
Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit
-
32
-
Schumm K, Rocha S, Caamano J, Perkins ND,. Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit. EMBO J 2006; 25: 4820 32.
-
(2006)
EMBO J
, vol.25
, pp. 4820
-
-
Schumm, K.1
Rocha, S.2
Caamano, J.3
Perkins, N.D.4
-
48
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
6
-
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E, Ben-Neriah Y,. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004; 431: 461 6.
-
(2004)
Nature
, vol.431
, pp. 461
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Urieli-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
49
-
-
33748075785
-
The retinoblastoma tumor-suppressor gene, the exception that proves the rule
-
43
-
Goodrich DW,. The retinoblastoma tumor-suppressor gene, the exception that proves the rule. Oncogene 2006; 25: 5233 43.
-
(2006)
Oncogene
, vol.25
, pp. 5233
-
-
Goodrich, D.W.1
-
50
-
-
28844453641
-
Induction of urothelial proliferation in rats by aristolochic acid through cell cycle progression via activation of cyclin D1/cdk4 and cyclin E/cdk2
-
35
-
Chang HR, Lian JD, Lo CW, Chang YC, Yang MY, Wang CJ,. Induction of urothelial proliferation in rats by aristolochic acid through cell cycle progression via activation of cyclin D1/cdk4 and cyclin E/cdk2. Food Chem Toxicol 2006; 44: 28 35.
-
(2006)
Food Chem Toxicol
, vol.44
, pp. 28
-
-
Chang, H.R.1
Lian, J.D.2
Lo, C.W.3
Chang, Y.C.4
Yang, M.Y.5
Wang, C.J.6
-
51
-
-
24344433172
-
ARF directly binds DP1: Interaction with DP1 coincides with the G1 arrest function of ARF
-
36
-
Datta A, Sen J, Hagen J, Korgaonkar CK, Caffrey M, Quelle DE, Hughes DE, Ackerson TJ, Costa RH, Raychaudhuri P,. ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF. Mol Cell Biol 2005; 25: 8024 36.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8024
-
-
Datta, A.1
Sen, J.2
Hagen, J.3
Korgaonkar, C.K.4
Caffrey, M.5
Quelle, D.E.6
Hughes, D.E.7
Ackerson, T.J.8
Costa, R.H.9
Raychaudhuri, P.10
-
53
-
-
0031828287
-
Predictive value of molecular alterations for the prognosis of urothelial carcinoma
-
9
-
Schulz WA, Jankevicius F, Gerharz CD, Kushima M, van Roeyen C, Bultel H, Gobell P, Schmitz-Drager BJ,. Predictive value of molecular alterations for the prognosis of urothelial carcinoma. Cancer Detect Prev 1998; 22: 422 9.
-
(1998)
Cancer Detect Prev
, vol.22
, pp. 422
-
-
Schulz, W.A.1
Jankevicius, F.2
Gerharz, C.D.3
Kushima, M.4
Van Roeyen, C.5
Bultel, H.6
Gobell, P.7
Schmitz-Drager, B.J.8
-
54
-
-
0028129547
-
Oncogene amplification in urothelial cancers with p53 gene mutation or MDM2 amplification
-
5
-
Habuchi T, Kinoshita H, Yamada H, Kakehi Y, Ogawa O, Wu WJ, Takahashi R, Sugiyama T, Yoshida O,. Oncogene amplification in urothelial cancers with p53 gene mutation or MDM2 amplification. J Natl Cancer Inst 1994; 86: 1331 5.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1331
-
-
Habuchi, T.1
Kinoshita, H.2
Yamada, H.3
Kakehi, Y.4
Ogawa, O.5
Wu, W.J.6
Takahashi, R.7
Sugiyama, T.8
Yoshida, O.9
-
55
-
-
0028871650
-
Inactivation of tumor suppressor genes and deregulation of the c-myc gene in urothelial cancer cell lines
-
300
-
Grimm MO, Jurgens B, Schulz WA, Decken K, Makri D, Schmitz-Drager BJ,. Inactivation of tumor suppressor genes and deregulation of the c-myc gene in urothelial cancer cell lines. Urol Res 1995; 23: 293 300.
-
(1995)
Urol Res
, vol.23
, pp. 293
-
-
Grimm, M.O.1
Jurgens, B.2
Schulz, W.A.3
Decken, K.4
Makri, D.5
Schmitz-Drager, B.J.6
-
56
-
-
0032970163
-
Over-expression and amplification of the c-myc gene in human urothelial carcinoma
-
73
-
Christoph F, Schmidt B, Schmitz-Drager BJ, Schulz WA,. Over-expression and amplification of the c-myc gene in human urothelial carcinoma. Int J Cancer 1999; 84: 169 73.
-
(1999)
Int J Cancer
, vol.84
, pp. 169
-
-
Christoph, F.1
Schmidt, B.2
Schmitz-Drager, B.J.3
Schulz, W.A.4
-
57
-
-
56749184298
-
Reflecting on 25 years with MYC
-
90
-
Meyer N, Penn LZ,. Reflecting on 25 years with MYC. Nat Rev 2008; 8: 976 90.
-
(2008)
Nat Rev
, vol.8
, pp. 976
-
-
Meyer, N.1
Penn, L.Z.2
-
58
-
-
27544468372
-
The Fos family of transcription factors and their role in tumourigenesis
-
61
-
Milde-Langosch K,. The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer 2005; 41: 2449 61.
-
(2005)
Eur J Cancer
, vol.41
, pp. 2449
-
-
Milde-Langosch, K.1
-
59
-
-
33747506490
-
Understanding urothelial carcinoma through cancer pathways
-
8
-
Schulz WA,. Understanding urothelial carcinoma through cancer pathways. Int J Cancer 2006; 119: 1513 8.
-
(2006)
Int J Cancer
, vol.119
, pp. 1513
-
-
Schulz, W.A.1
|