Induction of urothelial proliferation in rats by aristolochic acid through cell cycle progression via activation of cyclin D1/cdk4 and cyclin E/cdk2

Food and Chemical Toxicology

Volumn 44, Issue 1, 2006, Pages 28-35

  Chang, Horng Rong ^a,b   Lian, Jong Da ^a   Lo, Chia Wen ^b   Chang, Yun Ching ^b   Yang, Mon Yuan ^b   Wang, Chau Jong ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Aristolochic acid; Cell cycle; Urothelial proliferation

Indexed keywords

ARISTOLOCHIC ACID; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HISTOPATHOLOGY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; UROTHELIUM;

ADMINISTRATION, ORAL; ANIMALS; ARISTOLOCHIC ACIDS; CARCINOGENS; CELL CYCLE; CELL PROLIFERATION; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOPRECIPITATION; MALE; RATS; RATS, WISTAR; URINARY BLADDER; UROTHELIUM;

ANIMALIA;

EID: 28844453641     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.06.002     Document Type: Article

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