메뉴 건너뛰기




Volumn 11, Issue 4, 2010, Pages 455-460

Cardiac pathologies in relation to Smad-dependent pathways

Author keywords

Bone morphogenetic proteins; Cardiac diseases; Map kinase signaling system; Signal transduction; Smad proteins; Transforming growth factor b

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CD36 ANTIGEN; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 78249248682     PISSN: 15699293     EISSN: None     Source Type: Journal    
DOI: 10.1510/icvts.2010.234773     Document Type: Article
Times cited : (23)

References (51)
  • 1
    • 21644466165 scopus 로고    scopus 로고
    • Negative regulation of TGF-b signaling in development
    • Chen YG, Meng AM. Negative regulation of TGF-b signaling in development. Cell Res 2004;14:441-449.
    • (2004) Cell Res , vol.14 , pp. 441-449
    • Chen, Y.G.1    Meng, A.M.2
  • 3
    • 40849133772 scopus 로고    scopus 로고
    • Role of transforming growth factor-b superfamily signaling pathways in human disease
    • Gordon KJ, Blobe GC. Role of transforming growth factor-b superfamily signaling pathways in human disease. Biochim Biophys Acta 2008; 1782:197-228.
    • (2008) Biochim Biophys Acta , vol.1782 , pp. 197-228
    • Gordon, K.J.1    Blobe, G.C.2
  • 4
    • 0033012207 scopus 로고    scopus 로고
    • Signal transduction of the TGF-b superfamily by Smad proteins
    • Kawabata M, Miyazono K. Signal transduction of the TGF-b superfamily by Smad proteins. J Biochem 1999;125:9-16.
    • (1999) J Biochem , vol.125 , pp. 9-16
    • Kawabata, M.1    Miyazono, K.2
  • 7
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
    • Miyazono K, Maeda S, Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev 2005;16:251-263.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 8
    • 0031685620 scopus 로고    scopus 로고
    • TGF-b signal transduction
    • Massagué J. TGF-b signal transduction. Annu Rev Biochem 1998;67:753-791.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massagué, J.1
  • 10
    • 0031939744 scopus 로고    scopus 로고
    • Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
    • Nishimura R, Kato Y, Chen D, Harris SE, Mundy GR, Yoneda T. Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. J Biol Chem 1998;273:1872-1879.
    • (1998) J Biol Chem , vol.273 , pp. 1872-1879
    • Nishimura, R.1    Kato, Y.2    Chen, D.3    Harris, S.E.4    Mundy, G.R.5    Yoneda, T.6
  • 11
    • 31444446365 scopus 로고    scopus 로고
    • Cross-talk between bone morphogenetic protein 2 and leukemia inhibitory factor through ERK 1y2 and Smad1 in protection against doxorubicin-induced injury of cardiomyocytes
    • Izumi M, Masaki M, Hiramoto Y, Sugiyama S, Kuroda T, Terai K, Hori M, Kawase I, Hirota H. Cross-talk between bone morphogenetic protein 2 and leukemia inhibitory factor through ERK 1y2 and Smad1 in protection against doxorubicin-induced injury of cardiomyocytes. J Mol Cell Cardiol 2006;40:224-233.
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 224-233
    • Izumi, M.1    Masaki, M.2    Hiramoto, Y.3    Sugiyama, S.4    Kuroda, T.5    Terai, K.6    Hori, M.7    Kawase, I.8    Hirota, H.9
  • 13
    • 0346996450 scopus 로고    scopus 로고
    • Signal transduction of bone morphogenetic protein receptors
    • Nohe A, Keating E, Knaus P, Petersen NO. Signal transduction of bone morphogenetic protein receptors. Cell Signal 2004;16:291-299.
    • (2004) Cell Signal , vol.16 , pp. 291-299
    • Nohe, A.1    Keating, E.2    Knaus, P.3    Petersen, N.O.4
  • 14
    • 0030773834 scopus 로고    scopus 로고
    • Opposing BMP and EGF signaling pathways converge on the TGF-b family mediator Smad1
    • Kretzschmar M, Doody J, Massagué J. Opposing BMP and EGF signaling pathways converge on the TGF-b family mediator Smad1. Nature 1997;389:618-622.
    • (1997) Nature , vol.389 , pp. 618-622
    • Kretzschmar, M.1    Doody, J.2    Massagué, J.3
  • 15
    • 0036674213 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase is required for TGFb-mediated fibroblastic trans differentiation and cell migration
    • Bakin AV, Rinehart C, Tomlinson AK, Arteaga CL. p38 mitogen-activated protein kinase is required for TGFb-mediated fibroblastic trans differentiation and cell migration. J Cell Sci 2002;115(Pt 15):3193-3206.
    • (2002) J Cell Sci , vol.115 , Issue.Pt 15 , pp. 3193-3206
    • Bakin, A.V.1    Rinehart, C.2    Tomlinson, A.K.3    Arteaga, C.L.4
  • 16
    • 36448974832 scopus 로고    scopus 로고
    • Opposing effects of Wnt and MAPK on BMPySmad signal duration
    • Verheyen EM. Opposing effects of Wnt and MAPK on BMPySmad signal duration. Dev Cell 2007;13:755-756.
    • (2007) Dev Cell , vol.13 , pp. 755-756
    • Verheyen, E.M.1
  • 17
    • 67649378995 scopus 로고    scopus 로고
    • SMAD-proteins as a molecular switch from hypertrophy to apoptosis induction in adult ventricular cardiomyocytes
    • Heger J, Peters SC, Piper HM, Euler G. SMAD-proteins as a molecular switch from hypertrophy to apoptosis induction in adult ventricular cardiomyocytes. J Cell Physiol 2009;220:515-523.
    • (2009) J Cell Physiol , vol.220 , pp. 515-523
    • Heger, J.1    Peters, S.C.2    Piper, H.M.3    Euler, G.4
  • 18
    • 37549050584 scopus 로고    scopus 로고
    • Transforming growth factor-b receptor antagonism attenuates myocardial fibrosis in mice with cardiac-restricted overexpression of tumor necrosis factor
    • Sakata Y, Chancey AL, Divakaran VG, Sekiguchi K, Sivasubramanian N, Mann DL. Transforming growth factor-b receptor antagonism attenuates myocardial fibrosis in mice with cardiac-restricted overexpression of tumor necrosis factor. Basic Res Cardiol 2008;103:60-68.
    • (2008) Basic Res Cardiol , vol.103 , pp. 60-68
    • Sakata, Y.1    Chancey, A.L.2    Divakaran, V.G.3    Sekiguchi, K.4    Sivasubramanian, N.5    Mann, D.L.6
  • 20
    • 78249288342 scopus 로고    scopus 로고
    • Cardiovasc Res 2005;67:87-96.
    • (2005) Cardiovasc Res , vol.67 , pp. 87-96
  • 21
    • 33646076196 scopus 로고    scopus 로고
    • GDF15yMIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
    • Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. GDF15yMIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res 2006;98:342-350.
    • (2006) Circ Res , vol.98 , pp. 342-350
    • Xu, J.1    Kimball, T.R.2    Lorenz, J.N.3    Brown, D.A.4    Bauskin, A.R.5    Klevitsky, R.6    Hewett, T.E.7    Breit, S.N.8    Molkentin, J.D.9
  • 22
    • 70149110619 scopus 로고    scopus 로고
    • Heart-infiltrating prominin-1qy CD133q progenitor cells represent the cellular source of transforming growth factor b-mediated cardiac fibrosis in experimental autoimmune myocarditis
    • Kania G, Blyszczuk P, Stein S, Valaperti A, Germano D, Dirnhofer S, Hunziker L, Matter CM, Eriksson U. Heart-infiltrating prominin-1qy CD133q progenitor cells represent the cellular source of transforming growth factor b-mediated cardiac fibrosis in experimental autoimmune myocarditis. Circ Res 2009;105:462-470.
    • (2009) Circ Res , vol.105 , pp. 462-470
    • Kania, G.1    Blyszczuk, P.2    Stein, S.3    Valaperti, A.4    Germano, D.5    Dirnhofer, S.6    Hunziker, L.7    Matter, C.M.8    Eriksson, U.9
  • 24
    • 64649102284 scopus 로고    scopus 로고
    • Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload
    • Xia Y, Lee K, Li N, Corbett D, Mendoza L, Frangogiannis NG. Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol 2009;131:471-481.
    • (2009) Histochem Cell Biol , vol.131 , pp. 471-481
    • Xia, Y.1    Lee, K.2    Li, N.3    Corbett, D.4    Mendoza, L.5    Frangogiannis, N.G.6
  • 25
  • 27
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factor-b1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factor-b1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 2005;97:900-907.
    • (2005) Circ Res , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 28
    • 78249250769 scopus 로고    scopus 로고
    • [27] Gramley F, Lorenzen J, Koellensperger E, Kettering K, Weiss C, Munzel T. Atrial fibrosis and atrial fibrillation: the role of the TGF-b1 signaling pathway. Int J Cardiol 2009 Apr 23. wEpub ahead of printx.
  • 31
    • 43149103190 scopus 로고    scopus 로고
    • Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle
    • Dadlani H, Ballinger ML, Osman N, Getachew R, Little PJ. Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle. J Biol Chem 2008;283:7844-7852.
    • (2008) J Biol Chem , vol.283 , pp. 7844-7852
    • Dadlani, H.1    Ballinger, M.L.2    Osman, N.3    Getachew, R.4    Little, P.J.5
  • 32
    • 68949104261 scopus 로고    scopus 로고
    • Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis
    • Khanna AK. Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis. J Biomed Sci 2009;16:66.
    • (2009) J Biomed Sci , vol.16 , pp. 66
    • Khanna, A.K.1
  • 34
    • 0035834818 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-b signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice
    • Mallat Z, Gojova A, Marchiol-Fournigault C, Esposito B, Kamaté C, Merval R, Fradelizi D, Tedgui A. Inhibition of transforming growth factor-b signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice. Circ Res 2001;89:930-934.
    • (2001) Circ Res , vol.89 , pp. 930-934
    • Mallat, Z.1    Gojova, A.2    Marchiol-Fournigault, C.3    Esposito, B.4    Kamaté, C.5    Merval, R.6    Fradelizi, D.7    Tedgui, A.8
  • 35
    • 0034537229 scopus 로고    scopus 로고
    • Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro
    • Hao J, Wang B, Jones SC, Jassal DS, Dixon IM. Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro. Am J Physiol Heart Circ Physiol 2000;279:H3020-3030.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Hao, J.1    Wang, B.2    Jones, S.C.3    Jassal, D.S.4    Dixon, I.M.5
  • 37
    • 29144486106 scopus 로고    scopus 로고
    • The complex pattern of SMAD signaling in the cardiovascular system
    • Euler-Taimor G, Heger J. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc Res 2006;69:15-25.
    • (2006) Cardiovasc Res , vol.69 , pp. 15-25
    • Euler-Taimor, G.1    Heger, J.2
  • 38
    • 60249085947 scopus 로고    scopus 로고
    • Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS)
    • Maleszewski JJ, Miller DV, Lu J, Dietz HC, Halushka MK. Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS). Am J Surg Pathol 2009;33:194-201.
    • (2009) Am J Surg Pathol , vol.33 , pp. 194-201
    • Maleszewski, J.J.1    Miller, D.V.2    Lu, J.3    Dietz, H.C.4    Halushka, M.K.5
  • 42
    • 13444279874 scopus 로고    scopus 로고
    • Pathogenesis of pulmonary arterial hypertension: The need for multiple hits
    • Yuan JX, Rubin LJ. Pathogenesis of pulmonary arterial hypertension: the need for multiple hits. Circulation 2005;111:534-538.
    • (2005) Circulation , vol.111 , pp. 534-538
    • Yuan, J.X.1    Rubin, L.J.2
  • 43
    • 77951215757 scopus 로고    scopus 로고
    • Cross talk between Smad, MAPK and actin in the etiology of pulmonary arterial hypertension
    • West J. Cross talk between Smad, MAPK and actin in the etiology of pulmonary arterial hypertension. Adv Exp Med Biol 2010;661:265-278.
    • (2010) Adv Exp Med Biol , vol.661 , pp. 265-278
    • West, J.1
  • 44
    • 33645397400 scopus 로고    scopus 로고
    • Role of smadand wnt-dependent pathways in embryonic cardiac development
    • Pal R, Khanna A. Role of smadand wnt-dependent pathways in embryonic cardiac development. Stem Cells Dev 2006;15:29-39.
    • (2006) Stem Cells Dev , vol.15 , pp. 29-39
    • Pal, R.1    Khanna, A.2
  • 47
    • 70349599607 scopus 로고    scopus 로고
    • Miyazono K. c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-b signaling in diffuse-type gastric carcinoma
    • Kiyono K, Suzuki HI, Morishita Y, Komuro A, Iwata C, Yashiro M, Hirakawa K, Kano MR, Miyazono K. c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-b signaling in diffuse-type gastric carcinoma. Cancer Sci 2009;100:1809-1816.
    • (2009) Cancer Sci , vol.100 , pp. 1809-1816
    • Kiyono, K.1    Suzuki, H.I.2    Morishita, Y.3    Komuro, A.4    Iwata, C.5    Yashiro, M.6    Hirakawa, K.7    Kano, M.R.8
  • 48
    • 44949107350 scopus 로고    scopus 로고
    • Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
    • Cushing MC, Mariner PD, Liao JT, Sims EA, Anseth KS. Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. FASEB J 2008;22:1769-1777.
    • (2008) FASEB J , vol.22 , pp. 1769-1777
    • Cushing, M.C.1    Mariner, P.D.2    Liao, J.T.3    Sims, E.A.4    Anseth, K.S.5
  • 50
    • 41149122223 scopus 로고    scopus 로고
    • Atrial natriuretic peptide inhibits transforming growth factor b-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts
    • Li P, Wang D, Lucas J, Oparil S, Xing D, Cao X, Novak L, Renfrow MB, Chen YF. Atrial natriuretic peptide inhibits transforming growth factor b-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res 2008;102:185-192.
    • (2008) Circ Res , vol.102 , pp. 185-192
    • Li, P.1    Wang, D.2    Lucas, J.3    Oparil, S.4    Xing, D.5    Cao, X.6    Novak, L.7    Renfrow, M.B.8    Chen, Y.F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.