Dual G1 and G2/M phase inhibition by SC-ααδ9, a combinatorially derived Cdc25 phosphatase inhibitor

Oncogene

Volumn 18, Issue 50, 1999, Pages 6989-6996

  Tamura, Kenji ^a,c   Rice, Robert L ^a   Wipf, Peter ^b   Lazo, John S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Cdc2; Cdc25 phosphatase inhibitor; Cdk2; Cdk4; Cell cycle arrest; tsFT210

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; METAPHASE; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TEMPERATURE SENSITIVE MUTANT;

ANIMALIA;

EID: 0033604449     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203179     Document Type: Article

References (33)

1. Baratte B, Meijer L, Galaktionov K and Beach D. (1992). Anticancer Res., 12, 873-880.
2. Galaktionov K and Beach D. (1991). Cell, 67, 1181-1194.
3. Galaktionov K, Chen X and Beach D. (1996). Nature, 382, 511-517.
4. Galaktionov K, Lee AK, Eckstein J, Draetta G, Meckler J, Loda M and Beach D. (1995a). Science, 269, 1575-1577.
5. Galaktionov K, Jessus C and Beach D. (1995b). Genes Dev., 9, 1046-1058.
6. Garner-Hamrick PA and Fisher C. (1998). Int. J. Cancer, 76, 720-728.
7. Gasparotto D, Maestro R, Piccinin S, Vukosavljevic T, Barzan L, Sulfaro S and Boiocchi M. (1997). Cancer Res., 57, 2366-2368.
8. Gunasekera SP, McCarthy PJ, Kelly-Broges M, Lobkovsky E and Clardy J. (1996). J. Am. Chem. Soc., 118, 8759-8760.
9. Hamaguchi T, Sudo T and Osada H. (1995). FEBS Lett., 372, 54-58.
10. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW and Vogelstein B. (1997). Molecular Cell, 1, 3-11.
11. Hernandez S, Hernandez L, Bea S, Cazorla M, Fernandez PL, Nadal A, Muntane J, Mallofre C, Montserrat E, Cardesa A and Campo E. (1998). Cancer Res., 58, 1762-1767.
12. Hoffmann I, Clarke PR, Marcote MJ, Karsenti E and Draetta G. (1993). EMBO J., 12, 53-63.
13. Hoffmann I, Draetta G and Karsenti E. (1994). EMBO J., 13, 4302-4310.
14. Horiguchi T, Nishi T, Hakoda S, Tanida S, Nagata A and Okayama H. (1994). Biochem. Pharmacol., 48, 2139-2141.
15. Hunter T and Pines J. (1994). Cell, 79, 537-582.
16. Izumi T and Maller JL. (1993). Mol. Biol. Cell, 4, 1337-1350.
17. Jinno S, Hung SC and Okayama H. (1999). Oncogene, 18, 565-571.
18. Jinno S, Suto K, Nagata A, Igarashi M, Kanaoka Y, Nojima H and Okayama H. (1994). EMBO J., 13, 1549-1556.
19. Kakeya H, Onose R, Liu PC, Onozawa C, Matsumura F and Osada H. (1998). Cancer Res., 58, 704-710.
20. Lammer C, Wagerer S, Saffrich R, Mertens D, Ansorge W and Hoffmann I. (1998). J. Cell Sci., 111, 2445-2453.
21. Millar JB, Blevitt J, Gerace L, Sadhu K, Featherstone C and Russell P. (1991). Proc. Natl. Acad. Sci. USA, 88, 10500-10504.
22. Nagata A, Igarashi M, Jinno S, Suto K and Okayama H. (1991). New Biol., 3, 959-968.
23. Peng H and Zalkow LH. (1998). J. Med. Chem., 41, 4677-4680.
24. Rice RL, Rusnak JM, Yokokawa F, Yokokawa S, Messner DJ, Boynton AL, Wipf P and Lazo JS. (1997). Biochem., 36, 15965-15974.
25. Rice RL, Vogt A, Johnson CS, Yokokawa F, Yokokawa S, Wipf P and Lazo JS. (1998). Proc. Am. Assoc. Cancer Res., 39, 1208.
26. Sadhu K, Reed SI, Richardson H and Russell P. (1990). Proc. Natl. Acad. Sci. USA, 87, 5139-5143.
27. Sebastian B, Kakizuka A and Hunter T. (1993). Proc. Natl. Acad. Sci. USA, 90, 3521-3524.
28. Strausfeld U, Fernandez A, Capony JP, Girard F, Lautredou N, Derancourt J, Labbe JC and Lamb NJ. (1994). J. Biol. Chem., 269, 5989-6000.
29. Terada Y, Tatsuka M, Jinno S and Okayama H. (1995). Nature, 376, 358-362.
30. Th'ng JP, Wright PS, Hamaguchi J, Lee MG, Norbury CJ, Nurse P and Bradbury EM. (1990). Cell, 63, 313-324.
31. Vogt A, Rice RL, Settineri CE, Yokokawa F, Yokokawa S, Wipf P and Lazo JS. (1998). J. Pharmacol. Exp. Ther., 287, 806-813.
32. Wipf P, Cunningham A, Rice RL and Lazo JS. (1997). Bioorg. Med. Chem., 5, 165-177.
33. Wu W, Fan YH, Kemp BL, Walsh G and Mao L. (1998). Cancer Res., 58, 4082-4085.