Natural antioxidants synergistically enhance the anticancer potential of AP9-cd, a novel lignan composition from Cedrus deodara in human leukemia HL-60 cells

Chemico-Biological Interactions

Volumn 188, Issue 3, 2010, Pages 580-590

  Saxena, Arpita ^a   Saxena, A K ^a   Singh, Jaswant ^a   Bhushan, Shashi ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Acteoside; Antioxidants; AP9 cd; Curcumin; NF B; Silymarin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ACTEOSIDE; ANNEXIN; ANTIOXIDANT; AP 9CD; CURCUMIN; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SILYMARIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CEDRUS; CEDRUS DEODARA; CELL CYCLE PHASE; CELL PROLIFERATION; CELL STRAIN HL 60; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SCREENING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BIOLOGICAL PRODUCTS; CEDRUS; CELL CYCLE; CELL PROLIFERATION; DNA FRAGMENTATION; DOWN-REGULATION; DRUG SYNERGISM; FERRIC COMPOUNDS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCEINS; HL-60 CELLS; HUMANS; LEUKEMIA; LIGNANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NECROSIS; NF-KAPPA B; NITRIC OXIDE; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

CEDRUS DEODARA;

EID: 78149466067     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.09.029     Document Type: Article

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