Neurochemistry of sleep. an overview of animal experimental work

Handbook of Clinical Neurology

Volumn 98, Issue C, 2011, Pages 173-190

  Luppi, Pierre Hervé ^a   Fort, Patrice ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

ANIMAL; ANIMAL MODEL; BIOLOGICAL MODEL; BRAIN; CYTOLOGY; DRUG EFFECT; HUMAN; METABOLISM; NERVE CELL; NERVE TRACT; NEUROCHEMISTRY; PHYSIOLOGY; REVIEW; SLEEP;

ANIMALS; BRAIN; HUMANS; MODELS, ANIMAL; MODELS, NEUROLOGICAL; NEURAL PATHWAYS; NEUROCHEMISTRY; NEURONS; NEUROTRANSMITTER AGENTS; SLEEP;

EID: 78149401242     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-52006-7.00011-3     Document Type: Book

References (203)

1. Aghajanian G.K., VanderMaelen C.P. Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure. J Neurosci 1982, 2:1786-1792.
2. Airaksinen M.S., Alanen S., Szabat E., et al. Multiple neurotransmitters in the tuberomammillary nucleus: comparison of rat, mouse, and guinea pig. J Comp Neurol 1992, 323:103-116.
3. Alam M.N., Gong H., Alam T., et al. Sleep-waking discharge patterns of neurons recorded in the rat perifornical lateral hypothalamic area. J Physiol 2002, 538:619-631.
4. Alam M.N., Kumar S., Bashir T., et al. GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats. J Physiol 2005, 563:569-582.
5. Aserinsky E., Kleitman N. Regularly occurring periods of eye motility and concomitant phenomena during sleep. Science 1953, 118:273-274.
6. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981, 1:876-886.
7. Baghdoyan H.A. Cholinergic mechanisms regulating REM sleep. Sleep Science: Integrating Basic Research and Clinical Practice 1997, 88-116. S. Karger, Basel. W.J. Schwartz (Ed.).
8. Barnes N.M., Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999, 38:1083-1152. JID - 0236217.
9. Basheer R., Porkka-Heiskanen T., Stenberg D., et al. Adenosine and behavioral state control: adenosine increases c-Fos protein and AP1 binding in basal forebrain of rats. Brain Res Mol Brain Res 1999, 73:1-10. JID - 8908640.
10. Bayer L., Eggermann E., Serafin M., et al. Orexins (hypocretins) directly excite tuberomammillary neurons. Eur J Neurosci 2001, 14:1571-1575.
11. Bayer L., Mairet-Coello G., Risold P.Y., et al. Orexin/hypocretin neurons: chemical phenotype and possible interactions with melanin-concentrating hormone neurons. Regul Pept 2002, 104:33-39.
12. Benington J.H., Kodali S.K., Heller H.C. Stimulation of A1 adenosine receptors mimics the electroencephalographic effects of sleep deprivation. Brain Res 1995, 692:79-85. JID - 0045503.
13. Boissard R., Gervasoni D., Fort P., et al. Neuronal networks responsible for paradoxical sleep onset and maintenance in rats: a new hypothesis. Sleep 2000, 23(Suppl):107.
14. Boissard R., Gervasoni D., Schmidt M.H., et al. The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study. Eur J Neurosci 2002, 16:1959-1973.
15. Boissard R., Fort P., Gervasoni D., et al. Localization of the GABAergic and non-GABAergic neurons projecting to the sublaterodorsal nucleus and potentially gating paradoxical sleep onset. Eur J Neurosci 2003, 18:1627-1639.
16. Borbely A.A. A two process model of sleep regulation. Hum Neurobiol 1982, 1:195-204.
17. Borbely A.A. From slow waves to sleep homeostasis: new perspectives. Arch Ital Biol 2001, 139:53-61.
18. Bourgin P., Escourrou P., Gaultier C., et al. Induction of rapid eye movement sleep by carbachol infusion into the pontine reticular formation in the rat. Neuroreport 1995, 6:532-536.
19. Bourgin P., Huitron-Resendiz S., Spier A.D., et al. Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons. J Neurosci 2000, 20:7760-7765.
20. Brown R.E., Sergeeva O., Eriksson K.S., et al. Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat. Neuropharmacology 2001, 40:457-459.
21. Carli G., Zanchetti A. A study of pontine lesions suppressing deep sleep in the cat. Arch Ital Biol 1965, 103:751-788.
22. Chase M.H., Soja P.J., Morales F.R. Evidence that glycine mediates the postsynaptic potentials that inhibit lumbar motoneurons during the atonia of active sleep. J Neurosci 1989, 9:743-751.
23. Chemelli R.M., Willie J.T., Sinton C.M., et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999, 98:437-451.
24. Chou T.C., Bjorkum A.A., Gaus S.E., et al. Afferents to the ventrolateral preoptic nucleus. J Neurosci 2002, 22:977-990.
25. Chou T.C., Scammell T.E., Gooley J.J., et al. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci 2003, 23:10691-10702.
26. Crochet S., Sakai K. Alpha-2 adrenoceptor mediated paradoxical (REM) sleep inhibition in the cat. Neuroreport 1999, 10:2199-2204.
27. Crochet S., Sakai K. Effects of microdialysis application of monoamines on the EEG and behavioural states in the cat mesopontine tegmentum. Eur J Neurosci 1999, 11:3738-3752.
28. Darracq L., Gervasoni D., Souliere F., et al. Effect of strychnine on rat locus coeruleus neurones during sleep and wakefulness. Neuroreport 1996, 8:351-355.
29. Datta S., Hobson J.A. Neuronal activity in the caudo-lateral peribrachial pons: relationship to PGO waves and rapid eye movement. J Neurophysiol 1994, 71:95-109.
30. Datta S., Siwek D.F. Single cell activity patterns of pedunculopontine tegmentum neurons across the sleep-wake cycle in the freely moving rats. J Neurosci Res 2002, 70:611-621.
31. Datta S., Spoley E.E., Patterson E.H. Microinjection of glutamate into the pedunculopontine tegmentum induces REM sleep and wakefulness in the rat. Am J Physiol Regul Integr Comp Physiol 2001, 280:752-759.
32. De Andres I., Gomez-Montoya J., Gutierrez-Rivas E., et al. Differential action upon sleep states of ventrolateral and central areas of pontine tegmental field. Arch Ital Biol 1985, 123:1-11.
33. Deboer T., Sanford L.D., Ross R.J., et al. Effects of electrical stimulation in the amygdala on ponto-geniculo-occipital waves in rats. Brain Res 1998, 793:305-310.
34. de Lecea L., Kilduff T.S., Peyron C., et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A 1998, 95:322-327.
35. Dement W., Kleitman N. The relation of eye movements during sleep to dream activity: an objective method for the study of dreaming. J Exp Psychol Learn Mem Cogn 1957, 53:339-346.
36. Deurveilher S., Hars B., Hennevin E. Pontine microinjection of carbachol does not reliably enhance paradoxical sleep in rats. Sleep 1997, 20:593-607.
37. Deurveilher S., Burns J., Semba K. Indirect projections from the suprachiasmatic nucleus to the ventrolateral preoptic nucleus: a dual tract-tracing study in rat. Eur J Neurosci 2002, 16:1195-1213.
38. Eggermann E., Serafin M., Bayer L., et al. Orexins/hypocretins excite basal forebrain cholinergic neurones. Neuroscience 2001, 108:177-181.
39. Ennis M., Aston-Jones G. GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla. J Neurosci 1989, 9:2973-2981.
40. Eriksson K.S., Sergeeva O., Brown R.E., et al. Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus. J Neurosci 2001, 21:9273-9279.
41. Fenik V., Ogawa H., Davies R.O., et al. Pontine carbachol produces a spectrum of REM sleep-like and arousal-like electrocortical responses in urethane-anesthetized rats. Sleep Res Online 1999, 2(Suppl):30.
42. Fort P., Luppi P.H., Wenthold R., et al. [Glycine immunoreactive neurons in the medulla oblongata in cats.]. C R Acad Sci III 1990, 311:205-212.
43. Fort P., Luppi P.H., Jouvet M. Glycine-immunoreactive neurones in the cat brain stem reticular formation. Neuroreport 1993, 4:1123-1126.
44. Fort P., Gervasoni D., Peyron C., et al. GABAergic projections to the magnocellular preoptic area and substantia innominata in the rat. Neurosci Abstr, 423 1998.
45. Gallopin T., Fort P., Eggermann E., et al. Identification of sleep-promoting neurons in vitro. Nature 2000, 404:992-995.
46. Gallopin T., Luppi P.H., Rambert F.A., et al. Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study. Sleep 2004, 27:19-25.
47. Gallopin T., Luppi P.H., Cauli B., et al. The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A2A receptors in the ventrolateral preoptic nucleus. Neuroscience 2005, 134:1377-1390.
48. Gao X.B., van den Pol A.N. Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus. J Physiol 2001, 533:237-252.
49. Garzon M., De Andres I., Reinoso-Suarez F. Sleep patterns after carbachol delivery in the ventral oral pontine tegmentum of the cat. Neuroscience 1998, 83:1137-1144.
50. George R., Haslett W.L., Jenden D.J. A cholinergic mechanism in the brainstem reticular formation: induction of paradoxical sleep. Int J Neuropharmacol 1964, 3:541-552.
51. Gervasoni D., Darracq L., Fort P., et al. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. Eur J Neurosci 1998, 10:964-970.
52. Gervasoni D., Peyron C., Rampon C., et al. Role and origin of the GABAergic innervation of dorsal raphe serotonergic neurons. J Neurosci 2000, 20:4217-4225.
53. Gervasoni D., Panconi E., Henninot V., et al. Effect of chronic treatment with milnacipran on sleep architecture in rats compared with paroxetine and imipramine. Pharmacol Biochem Behav 2002, 73:557-563.
54. Gnadt J.W., Pegram G.V. Cholinergic brainstem mechanisms of REM sleep in the rat. Brain Res 1986, 384:29-41.
55. Goutagny R., Comte J.C., Salvert D., et al. Paradoxical sleep in mice lacking M(3) and M(2)/M(4) muscarinic receptors. Neuropsychobiology 2005, 52:140-146.
56. Goutagny R., Luppi P.H., Salvert D., et al. GABAergic control of hypothalamic melanin-concentrating hormone-containing neurons across the sleep-waking cycle. Neuroreport 2005, 16:1069-1073.
57. Goutagny R., Luppi P.H., Salvert D., et al. Role of the dorsal paragigantocellular reticular nucleus in paradoxical (rapid eye movment) sleep generation: a combined electrophysiological and anatomical study in the rat. Neuroscience 2005, 152:849-857.
58. Guan J.L., Uehara K., Lu S., et al. Reciprocal synaptic relationships between orexin- and melanin-concentrating hormone-containing neurons in the rat lateral hypothalamus: a novel circuit implicated in feeding regulation. Int J Obes Relat Metab Disord 2002, 26:1523-1532.
59. Guyenet P.G., Aghajanian G.K. Ach, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action. Eur J Pharmacol 1979, 53:319-328.
60. Hagan J.J., Leslie R.A., Patel S., et al. Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci U S A 1999, 96:10911-10916.
61. Hervieu G.J., Cluderay J.E., Harrison D.C., et al. Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord. Neuroscience 2001, 103:777-797.
62. Hobson J.A., Mccarley R.W., Wyzinski P.W. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975, 189:55-58.
63. Holmes C.J., Jones B.E. Importance of cholinergic, GABAergic, serotonergic and other neurons in the medial medullary reticular formation for sleep-wake states studied by cytotoxic lesions in the cat. Neuroscience 1994, 62:1179-1200.
64. Holstege J.C., Bongers C.M. A glycinergic projection from the ventromedial lower brainstem to spinal motoneurons. An ultrastructural double labeling study in rat. Brain Res 1991, 566:308-315.
65. Horner R.L., Kubin L. Pontine carbachol elicits multiple rapid eye movement sleep-like neural events in urethane-anaesthetized rats. Neuroscience 1999, 93:215-226.
66. Horvath T.L., Peyron C., Diano S., et al. Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J Comp Neurol 1999, 415:145-159.
67. Huang Z.L., Qu W.M., Li W.D., et al. Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci U S A 2001, 98:9965-9970.
68. Huang Z.L., Qu W.M., Eguchi N., et al. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci 2005, 8:858-859.
69. Jacobs B.L. Overview of the activity of brain monoaminergic neurons across the sleep-wake cycle. Sleep: Neurotransmitters and Neuromodulators 1985, 1-14. Raven Press, New York. A. Wauquier, J.M. Gaillard, J.M. Monti (Eds.).
70. Jones B.E. Noradrenergic locus coeruleus neurons: their distant connections and their relationship to neighboring (including cholinergic and GABAergic) neurons of the central gray and reticular formation. Prog Brain Res 1991, 88:15-30.
71. Jones B.E. Paradoxical sleep and its chemical/structural substrates in the brain. Neuroscience 1991, 40:637-656.
72. Jones B. The organization of central cholinergic systells and their functional importance in sleep-waking states. Cholinergic Function and Dysfunction. Progress in Brain Research 1993, Elsevier, Amsterdam. A. Cuello (Ed.).
73. Jones B.E. The organization of central cholinergic systems and their functional importance in sleep-waking states. Prog Brain Res 1993, 98:61-71.
74. Jones B.E. Basic mechanisms of sleep-wake states. Principles and Practice of Sleep Medicine 1994, 61-71. WB Saunders, Philadelphia. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
75. Jouvet M. Recherches sur les structures nerveuses et les mécanismes responsables des différentes phases du sommeil physiologique. Arch Ital Biol 1962, 100:125-206.
76. Jouvet M. Biogenic amines and the states of sleep. Science 1969, 163:32-41.
77. Jouvet M. The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle. Ergeb Physiol 1972, 64:166-307.
78. Jouvet M. Cholinergic mechanisms and sleep. Cholinergic Mechanisms 1975, 455-476. Raven Press, New York. P.G. Waser (Ed.).
79. Jouvet M. The regulation of paradoxical sleep by the hypothalamo-hypophysis. Arch Ital Biol 1988, 126:259-274.
80. Jouvet M., Michel F. Electromyographic correlations of sleep in the chronic decorticate and mesencephalic cat. CR Séances Soc Biol (Paris) 1959, 153:422-425.
81. Kaur S., Saxena R.N., Mallick B.N. GABAergic neurons in prepositus hypoglossi regulate REM sleep by its action on locus coeruleus in freely moving rats. Synapse 2001, 42:141-150.
82. Kayama Y., Ohta M., Jodo E. Firing of 'possibly' cholinergic neurons in the rat laterodorsal tegmental nucleus during sleep and wakefulness. Brain Res 1992, 569:210-220.
83. Kilduff T.S., Peyron C. The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders. Trends Neurosci 2000, 23:359-365.
84. Kodama T., Lai Y.Y., Siegel J.M. Enhanced glutamate release during REM sleep in the rostromedial medulla as measured by in vivo microdialysis. Brain Res 1998, 780:178-181.
85. Kodama T., Lai Y.Y., Siegel J.M. Changes in inhibitory amino acid release linked to pontine-induced atonia: an in vivo microdialysis study. J Neurosci 2003, 23:1548-1554.
86. Kohlmeier K.A., Lopez-Rodriguez F., Liu R.H., et al. State-dependent phenomena in cat masseter motoneurons. Brain Res 1996, 722:30-38.
87. Koyama Y., Kayama Y. Mutual interactions among cholinergic, noradrenergic and serotonergic neurons studied by ionophoresis of these transmitters in rat brainstem nuclei. Neuroscience 1993, 55:1117-1126.
88. Koyama Y., Takahashi K., Kodama T., et al. State-dependent activity of neurons in the perifornical hypothalamic area during sleep and waking. Neuroscience 2003, 119:1209-1219.
89. Krueger J.M. Cytokines and sleep regulation. Handbook of Behavioral State Control. Cellular and Molecular Mechanisms 1999, 609-622. CRC Press, New-York. R. Lydic, H.A. Baghdoyan (Eds.).
90. Krueger J.M., Majde J.A. Humoral links between sleep and the immune system: research issues. Ann N Y Acad Sci 2003, 992:9-20.
91. Lai Y.Y., Siegel J.M. Cardiovascular and muscle tone changes produced by microinjection of cholinergic and glutamatergic agonists in dorsolateral pons and medial medulla. Brain Res 1990, 514:27-36.
92. Lai Y.Y., Siegel J.M. Pontomedullary glutamate receptors mediating locomotion and muscle tone suppression. J Neurosci 1991, 11:2931-2937.
93. Lee M.G., Hassani O.K., Jones B.E. Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J Neurosci 2005, 25:6716-6720.
94. Levine E.S., Jacobs B.L. Neurochemical afferents controlling the activity of serotonergic neurons in the dorsal raphe nucleus: microiontophoretic studies in the awake cat. J Neurosci 1992, 12:4037-4044.
95. Li Y.Q., Takada M., Kaneko T., et al. GABAergic and glycinergic neurons projecting to the trigeminal motor nucleus: a double labeling study in the rat. J Comp Neurol 1996, 373:498-510.
96. Lin J.S., Sakai K., Vanni-Mercier G., et al. A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats. Brain Res 1989, 479:225-240.
97. Lin J.S., Roussel B., Akaoka H., et al. Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the cat. Brain Res 1992, 591:319-326.
98. Lin J.S., Hou Y., Sakai K., et al. Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. J Neurosci 1996, 16:1523-1537.
99. Lin L., Faraco J., Li R., et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999, 98:365-376.
100. Liu R., Jolas T., Aghajanian G. Serotonin 5-HT(2) receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus. Brain Res 2000, 873:34-45.
101. Liu R.J., Van Den Pol A.N., Aghajanian G.K. Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions. J Neurosci 2002, 22:9453-9464.
102. Lu J., Shiromani P., Saper C.B. Retinal input to the sleep-active ventrolateral preoptic nucleus in the rat. Neuroscience 1999, 93:209-214. JID - 7605074.
103. Lu J., Greco M.A., Shiromani P., et al. Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep. J Neurosci 2000, 20:3830-3842. JID - 8102140.
104. Lu J., Bjorkum A.A., Xu M., et al. Selective activation of the extended ventrolateral preoptic nucleus during rapid eye movement sleep. J Neurosci 2002, 22:4568-4576. JID - 8102140.
105. Luppi P.H., Sakai K., Fort P., et al. The nuclei of origin of monoaminergic, peptidergic, and cholinergic afferents to the cat nucleus reticularis magnocellularis: a double-labeling study with cholera toxin as a retrograde tracer. J Comp Neurol 1988, 277:1-20.
106. Luppi P.H., Charlety P.J., Fort P., et al. Anatomical and electrophysiological evidence for a glycinergic inhibitory innervation of the rat locus coeruleus. Neurosci Lett 1991, 128:33-36.
107. Luppi P.H., Aston-Jones G., Akaoka H., et al. Afferent projections to the rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin. Neuroscience 1995, 65:119-160.
108. Luppi P.H., Gervasoni D., Peyron C., et al. Norepinephrine and REM Sleep. Rapid Eye Movement Sleep 1999, 107-122. Norosa Publishing House, New Delhi. B.N. Mallick, S. Inoue (Eds.).
109. McCarley R.W., Hobson J.A. Neuronal excitability modulation over the sleep cycle: a structural and mathematical model. Science 1975, 189:58-60.
110. McGinty D.J., Harper R.M. Dorsal raphe neurons: depression of firing during sleep in cats. Brain Res 1976, 101:569-575.
111. McGinty D., Szymusiak R. Hypothalamic regulation of sleep and arousal. Front Biosci 2003, 8:s1074-s1083.
112. McGinty D., Alam M.N., Szymusiak R., et al. Hypothalamic sleep-promoting mechanisms: coupling to thermoregulation. Arch Ital Biol 2001, 139:63-75. JID - 0372441.
113. Maloney K.J., Mainville L., Jones B.E. Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery. J Neurosci 1999, 19:3057-3072.
114. Maloney K.J., Mainville L., Jones B.E. c-Fos expression in GABAergic, serotonergic, and other neurons of the pontomedullary reticular formation and raphe after paradoxical sleep deprivation and recovery. J Neurosci 2000, 20:4669-4679.
115. Maquet P., Peters J., Aerts J., et al. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature 1996, 383:163-166.
116. Marcus J.N., Aschkenasi C.J., Lee C.E., et al. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 2001, 435:6-25.
117. Matsuo S., Jang I.S., Nabekura J., et al. Alpha 2-adrenoceptor-mediated presynaptic modulation of GABAergic transmission in mechanically dissociated rat ventrolateral preoptic neurons. J Neurophysiol 2003, 89:1640-1648.
118. Mileykovskiy B.Y., Kiyashchenko L.I., Siegel J.M. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 2005, 46:787-798.
119. Morales F.R., Sampogna S., Yamuy J., et al. c-Fos expression in brainstem premotor interneurons during cholinergically induced active sleep in the cat. J Neurosci 1999, 19:9508-9518.
120. Moruzzi G.M.H. Brain stem reticular formation and activation of the EEG. J Clin Neurosci 1949, 7:251-267.
121. Moruzzi G. The sleep-waking cycle. Ergeb Physiol 1972, 64:1-165.
122. Nakamura T., Uramura K., Nambu T., et al. Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system. Brain Res 2000, 873:181-187.
123. Nauta W.J. Hypothalamic regulation of sleep in rats. Experimental study. J Neurophysiol 1946, 9:285-316.
124. Nishino S., Ripley B., Overeem S., et al. Hypocretin (orexin) deficiency in human narcolepsy. Lancet 2000, 355:39-40. JID - 2985213R.
125. Nitz D., Siegel J. GABA release in the dorsal raphe nucleus: role in the control of REM sleep. Am J Physiol 1997, 273:R451-R455.
126. Nitz D., Siegel J.M. GABA release in the locus coeruleus as a function of sleep/wake state. Neuroscience 1997, 78:795-801.
127. Novak C.M., Nunez A.A. Daily rhythms in Fos activity in the rat ventrolateral preoptic area and midline thalamic nuclei. Am J Physiol 1998, 275:R1620-R1626. JID - 0370511.
128. Novak C.M., Nunez A.A. A sparse projection from the suprachiasmatic nucleus to the sleep active ventrolateral preoptic area in the rat. Neuroreport 2000, 11:93-96. JID - 9100935.
129. Obal F., Krueger J.M. Biochemical regulation of non-rapid-eye-movement sleep. Front Biosci 2003, 8:d520-d550.
130. Onoe H., Sakai K. Kainate receptors: a novel mechanism in paradoxical (REM) sleep generation. Neuroreport 1995, 6:353-356.
131. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 1997, Academic Press, Sydney.
132. Peyron C., Tighe D.K., Van Den Pol A.N., et al. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 1998, 18:9996-10015.
133. Peyron C., Faraco J., Rogers W., et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000, 6:991-997.
134. Pollock M.S., Mistlberger R.E. Rapid eye movement sleep induction by microinjection of the GABA-A antagonist bicuculline into the dorsal subcoeruleus area of the rat. Brain Res 2003, 962:68-77.
135. Porkka-Heiskanen T., Strecker R.E., Thakkar M., et al. Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness. Science 1997, 276:1265-1268.
136. Porkka-Heiskanen T., Strecker R.E., Mccarley R.W. Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience 2000, 99:507-517. JID - 7605074.
137. Portas C.M., Thakkar M., Rainnie D.G., et al. Role of adenosine in behavioral state modulation: a microdialysis study in the freely moving cat. Neuroscience 1997, 79:225-235.
138. Rainnie D.G., Grunze H.C., McCarley R.W., et al. Adenosine inhibition of mesopontine cholinergic neurons: implications for EEG arousal. Science 1994, 263:689-692.
139. Rampon C., Luppi P.H., Fort P., et al. Distribution of glycine-immunoreactive cell bodies and fibers in the rat brain. Neuroscience 1996, 75:737-755.
140. Rampon C., Peyron C., Petit J.M., et al. Origin of the glycinergic innervation of the rat trigeminal motor nucleus. Neuroreport 1996, 7:3081-3085.
141. Ranson S.W. Somnolence caused by hypothalamic lesions in the monkey. Arch Neurol Psychiatr 1939, 41:1-23.
142. Sakai K. Neurons responsible for paradoxical sleep. Sleep: Neurotransmitters and Neuromodulators 1985, 29-42. Raven Press, New York. A. Wauquier, Janssen Research Foundation (Eds.).
143. Sakai K. Central mechanisms of paradoxical sleep. Brain Dev 1986, 8:402-407.
144. Sakai K., Crochet S. Serotonergic dorsal raphe neurons cease firing by disfacilitation during paradoxical sleep. Neuroreport 2000, 11:3237-3241.
145. Sakai K., Koyama Y. Are there cholinergic and non-cholinergic paradoxical sleep-on neurones in the pons?. Neuroreport 1996, 7:2449-2453.
146. Sakai K., Sastre J.P., Salvert D., et al. Tegmentoreticular projections with special reference to the muscular atonia during paradoxical sleep in the cat: an HRP study. Brain Res 1979, 176:233-254.
147. Sakai K., Sastre J.P., Kanamori N., et al. State-specific neurones in the ponto-medullary reticular formation with special reference to the postural atonia during paradoxical sleep in the cat. Brain Mechanisms of Perceptual Awareness and Purposeful Behavior 1981, Raven Press, New York. O. Pompeiano, C. Aimone Marsan (Eds.).
148. Sakai K., Crochet S., Onoe H. Pontine structures and mechanisms involved in the generation of paradoxical (REM) sleep. Arch Ital Biol 2001, 139:93-107.
149. Sakurai T., Amemiya A., Ishii M., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998, 92:573-585.
150. Sallanon M., Sakai K., Buda C., et al. Increase of paradoxical sleep induced by microinjections of ibotenic acid into the ventrolateral part of the posterior hypothalamus in the cat. Arch Ital Biol 1988, 126:87-97.
151. Sallanon M., Denoyer M., Kitahama K., et al. Long-lasting insomnia induced by preoptic neuron lesions and its transient reversal by muscimol injection into the posterior hypothalamus in the cat. Neuroscience 1989, 32:669-683.
152. Sanford L.D., Tang X., Xiao J., et al. GABAergic regulation of REM sleep in reticularis pontis oralis and caudalis in rats. J Neurophysiol 2003, 90:938-945.
153. Saper C.B., Chou T.C., Scammell T.E. The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci 2001, 24:726-731.
154. Sastre J.P., Sakai K., Jouvet M. Are the gigantocellular tegmental field neurons responsible for paradoxical sleep?. Brain Res 1981, 229:147-161.
155. Sastre J.P., Buda C., Kitahama K., et al. Importance of the ventrolateral region of the periaqueductal gray and adjacent tegmentum in the control of paradoxical sleep as studied by muscimol microinjections in the cat. Neuroscience 1996, 74:415-426.
156. Sastre J.P., Buda C., Lin J.S., et al. Differential c-Fos expression in the rhinencephalon and striatum after enhanced sleep-wake states in the cat. Eur J Neurosci 2000, 12:1397-1410.
157. Satoh S., Matsumura H., Suzuki F., et al. Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats. Proc Natl Acad Sci U S A 1996, 93:5980-5984. JID - 7505876.
158. Scammell T.E., Gerashchenko D.Y., Mochizuki T., et al. An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience 2001, 107:653-663. JID - 7605074.
159. Schmidt M.H., Valatx J.L., Sakai K., et al. Role of the lateral preoptic area in sleep-related erectile mechanisms and sleep generation in the rat. J Neurosci 2000, 20:6640-6647.
160. Schmidt M.H., Gervasoni D., Luppi P.H., et al. Carbachol administration into the lateral preoptic area induces penile erections and wakefulness. Neurosci Abstr 2001, 522.
161. Schmidt M.H., Gervasoni D., Luppi P.H., et al. The ventrolateral preoptic area: role and origin of cholinergic input in the control of wakefulness and penile erections. Sleep 2002, 25(Suppl).
162. Schmidt M.H., Gervasoni D., Luppi P.H., et al. Quantitative analysis of cholinergic afferents to the ventrolateral preoptic area: role in waking mechanisms. Sleep 2003, 26(Suppl):0089.
163. Sherin J.E., Shiromani P.J., McCarley R.W., et al. Activation of ventrolateral preoptic neurons during sleep. Science 1996, 271:216-219.
164. Sherin J.E., Elmquist J.K., Torrealba F., et al. Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. J Neurosci 1998, 18:4705-4721.
165. Shiromani P.J., Fishbein W. Continuous pontine cholinergic microinfusion via mini-pump induces sustained alterations in rapid eye movement (REM) sleep. Pharmacol Biochem Behav 1986, 25:1253-1261.
166. Shiromani P., Scammell T., Sherin J.E., et al. Hypothalamic regulation of sleep. Handbook of Behavioral State Control. Cellular and Molecular Machanisms 1999, 311-325. CRC Press, New York. R. Lydic, H.A. Baghdoyan (Eds.).
167. Siegel J.M., Wheeler R.L., McGinty D.J. Activity of medullary reticular formation neurons in the unrestrained cat during waking and sleep. Brain Res 1979, 179:49-60.
168. Soja P.J., Lopez-Rodriguez F., Morales F.R., et al. The postsynaptic inhibitory control of lumbar motoneurons during the atonia of active sleep: effect of strychnine on motoneuron properties. J Neurosci 1991, 11:2804-2811.
169. Steininger T.L., Alam M.N., Gong H., et al. Sleep-waking discharge of neurons in the posterior lateral hypothalamus of the albino rat. Brain Res 1999, 840:138-147.
170. Steininger T.L., Gong H., Mcginty D., et al. Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups. J Comp Neurol 2001, 429:638-653.
171. Stenberg D., Litonius E., Halldner L., et al. Sleep and its homeostatic regulation in mice lacking the adenosine A1 receptor. J Sleep Res 2003, 12:283-290.
172. Sun X., Whitefield S., Rusak B., et al. Electrophysiological analysis of suprachiasmatic nucleus projections to the ventrolateral preoptic area in the rat. Eur J Neurosci 2001, (14):1257-1274. JID - 8918110.
173. Swanson L.W. Brain Maps: Structure of the Rat Brain: A Laboratory Guide with Printed and Electronic Templates for Data, Models, and Schematics 1998, Elsevier, New York.
174. Swett C.P., Hobson J.A. The effects of posterior hypothalamic lesions on behavioral and electrographic manifestations of sleep and waking in cats. Arch Ital Biol 1968, 106:283-293.
175. Szymusiak R., Alam N., Steininger T.L., et al. Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res 1998, 803:178-188.
176. Szymusiak R., Steininger T., Alam N., et al. Preoptic area sleep-regulating mechanisms. Arch Ital Biol 2001, 139:77-92.
177. Taguchi O., Kubin L., Pack A.I. Evocation of postural atonia and respiratory depression by pontine carbachol in the decerebrate rat. Brain Res 1992, 595:107-115.
178. Thompson R.H., Canteras N.S., Swanson L.W. Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat. J Comp Neurol 1996, 376:143-173. JID - 0406041.
179. Tononi G., Pompeiano M., Cirelli C. Suppression of desynchronized sleep through microinjection of the alpha 2-adrenergic agonist clonidine in the dorsal pontine tegmentum of the cat. Pflugers Arch 1991, 418:512-518.
180. Torterolo P., Yamuy J., Sampogna S., et al. Hypocretinergic neurons are primarily involved in activation of the somatomotor system. Sleep 2003, 26:25-28.
181. Trivedi P., Yu H., Macneil D.J., et al. Distribution of orexin receptor mrna in the rat brain. FEBS Lett 1998, 438:71-75.
182. Urade Y., Eguchi N., Qu W.M., et al. Minireview: sleep regulation in adenosine A(2A) receptor-deficient mice. Neurology 2003, 61:S94-S96.
183. van den Pol A.N. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J Neurosci 1999, 19:3171-3182.
184. Vanni-Mercier G., Sakai K., Jouvet M. [Specific neurons for wakefulness in the posterior hypothalamus in the cat]. C R Acad Sci III 1984, 298:195-200.
185. Vanni-Mercier G., Sakai K., Lin J.S., et al. Mapping of cholinoceptive brainstem structures responsible for the generation of paradoxical sleep in the cat. Arch Ital Biol 1989, 127:133-164.
186. Velazquez-Moctezuma J., Gillin J.C., Shiromani P.J. Effect of specific M1, M2 muscarinic receptor agonists on REM sleep generation. Brain Res 1989, 503:128-131.
187. Verret L., Goutagny R., Fort P., et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci 2003, 4:19.
188. Verret L., Leger L., Fort P., et al. Cholinergic and noncholinergic brainstem neurons expressing Fos after paradoxical (REM) sleep deprivation and recovery. Eur J Neurosci 2005, 21:2488-2504.
189. Verret L., Fort P., Gervasoni D., et al. Localization of the neurons active during paradoxical (REM) sleep and projecting to the locus coeruleus noradrenergic neurons in the rat. J Comp Neurol 2005, 495:573-586.
190. von Economo C. Die Pathologie des Schlafes. Handbuch des Normalen und Pathologischen Physiologie 1926, Springer, Berlin. A. Von Bethe, G.V. Bergman, G. Embden (Eds.).
191. von Economo C. Schlaftheorie. Ergeb Physiol 1929, 55:121-135.
192. Watts A.G., Swanson L.W., Sanchez-Watts G. Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J Comp Neurol 1987, 258:204-229. JID - 0406041.
193. Webster H.H., Jones B.E. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. II. Effects upon sleep-waking states. Brain Res 1988, 458:285-302.
194. Woch G., Davies R.O., Pack A.I., et al. Behaviour of raphe cells projecting to the dorsomedial medulla during carbachol-induced atonia in the cat. J Physiol 1996, 490(Pt 3):745-758.
195. Xi M.C., Morales F.R., Chase M.H. Evidence that wakefulness and REM sleep are controlled by a GABAergic pontine mechanism. J Neurophysiol 1999, 82:2015-2019.
196. Xi M.C., Morales F.R., Chase M.H. The motor inhibitory system operating during active sleep is tonically suppressed by GABAergic mechanisms during other states. J Neurophysiol 2001, 86:1908-1915.
197. Xi M.C., Morales F.R., Chase M.H. Interactions between GABAergic and cholinergic processes in the nucleus pontis oralis: neuronal mechanisms controlling active (rapid eye movement) sleep and wakefulness. J Neurosci 2004, 24:10670-10678.
198. Yamamoto K., Mamelak A.N., Quattrochi J.J., et al. A cholinoceptive desynchronized sleep induction zone in the anterodorsal pontine tegmentum: locus of the sensitive region. Neuroscience 1990, 39:279-293.
199. Yamanaka A., Tsujino N., Funahashi H., et al. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochem Biophys Res Commun 2002, 290:1237-1245.
200. Yamuy J., Sampogna S., Lopez-Rodriguez F., et al. Fos and serotonin immunoreactivity in the raphe nuclei of the cat during carbachol-induced active sleep: a double-labeling study. Neuroscience 1995, 67:211-223.
201. Yamuy J., Fung S.J., Xi M., et al. Hypoglossal motoneurons are postsynaptically inhibited during carbachol-induced rapid eye movement sleep. Neuroscience 1999, 94:11-15.
202. Yoshida Y., Fujiki N., Nakajima T., et al. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. Eur J Neurosci 2001, 14:1075-1081.
203. Zeitzer J.M., Buckmaster C.L., Parker K.J., et al. Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. J Neurosci 2003, 23:3555-3560.