Lung protease/anti-protease network and modulation of mucus production and surfactant activity

Biochimie

Volumn 92, Issue 11, 2010, Pages 1608-1617

  Garcia Verdugo, Ignacio ^a,b   Descamps, Delphyne ^a,b   Chignard, Michel ^a,b   Touqui, Lhousseine ^a,b   Sallenave, Jean Michel ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

Author keywords

Elafin; Mucus; Neutrophil elastase; SLPI; Surfactant proteins

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; BACTERIAL PROTEASE; COLLECTIN; DISINTEGRIN; ELAFIN; ELASTASE; HUMAN AIRWAY TRYPSIN LIKE PROTEASE; IODOACETAMIDE; LEUKOCYTE ELASTASE; LUNG ENZYME; LUNG SURFACTANT; MARIMASTAT; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; MUCIN; PHOSPHORAMIDON; PROTEINASE; PROTEINASE INHIBITOR; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SIVELESTAT; SURFACTANT PROTEIN A; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C; SURFACTANT PROTEIN D; TRYPSIN LIKE SERINE PROTEASE INHIBITOR; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; UNCLASSIFIED DRUG;

AIRWAY; ANTIINFLAMMATORY ACTIVITY; ASTHMA; BACTERIAL PNEUMONIA; BRONCHUS MUCUS; CELL ADHESION; CELL FUSION; CELL MIGRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME SYNTHESIS; FIBROSING ALVEOLITIS; HOMEOSTASIS; HUMAN; IMMUNOMODULATION; INNATE IMMUNITY; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG INFECTION; MOLECULAR INTERACTION; MUCUS SECRETION; NEOPLASM; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA; REVIEW;

ANIMALS; HUMANS; LUNG; MUCINS; MUCUS; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; PULMONARY SURFACTANTS;

EID: 78149360115     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.05.010     Document Type: Review

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