The mood stabilizer valproic acid improves defective neurite formation caused by charcot-marie-tooth disease-associated mutant Rab7 through the JNK signaling pathway

Journal of Neuroscience Research

Volumn 88, Issue 14, 2010, Pages 3189-3197

  Yamauchi, Junji ^a,b,c   Torii, Tomohiro ^a   Kusakawa, Shinji ^a   Sanbe, Atsushi ^a   Nakamura, Kazuaki ^a   Takashima, Shou ^a,d   Hamasaki, Hajime ^a,b   Kawaguchi, Shogo ^a,b   Miyamoto, Yuki ^a   Tanoue, Akito ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c Japan Health Sciences Foundation   (Japan)

^d NOGUCHI INSTITUTE   (Japan)

Author keywords

CMT2B; JNK; Neuritogenesis; Rab7; VPA

Indexed keywords

RAB7 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; VALPROIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; ENZYME ACTIVITY; HEREDITARY MOTOR SENSORY NEUROPATHY; IN VITRO STUDY; MOUSE; NERVE CELL; NEURITE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CHARCOT-MARIE-TOOTH DISEASE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MUTATION; NERVE DEGENERATION; NEURITES; NEUROPROTECTIVE AGENTS; RAB GTP-BINDING PROTEINS; RATS; VALPROIC ACID;

EID: 78149353040     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22460     Document Type: Article

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