-
1
-
-
0037044785
-
-
Arthur, W.T., S.M. Ellerbroek, C.J. Der, K. Burridge, and K. Wennerberg. 2002. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC. J. Biol. Chem. 277:42964-42972.
-
Arthur, W.T., S.M. Ellerbroek, C.J. Der, K. Burridge, and K. Wennerberg. 2002. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC. J. Biol. Chem. 277:42964-42972.
-
-
-
-
2
-
-
34250693117
-
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development
-
Benninger, Y., T. Thurnherr, J.A. Pereira, S. Krause, X. Wu, A. Chrostek-Grashoff, D. Herzog, K.A. Nave, R.J. Franklin, D. Meijer, et al. 2007. Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J. Cell Biol. 177:1051-1061.
-
(2007)
J. Cell Biol
, vol.177
, pp. 1051-1061
-
-
Benninger, Y.1
Thurnherr, T.2
Pereira, J.A.3
Krause, S.4
Wu, X.5
Chrostek-Grashoff, A.6
Herzog, D.7
Nave, K.A.8
Franklin, R.J.9
Meijer, D.10
-
3
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera, E., L. Haney, C. Grimsley, M. Lu, S.F. Walk, A.C. Tosello-Trampont, I.G. Macara, H. Madhani, G.R. Fink, and K.S. Ravichandran. 2002. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat. Cell Biol. 4:574-582.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
Macara, I.G.7
Madhani, H.8
Fink, G.R.9
Ravichandran, K.S.10
-
4
-
-
0027487867
-
Expanding roles for the Schwann cell: Ensheathment, myelination, trophism and regeneration
-
Bunge, R.P. 1993. Expanding roles for the Schwann cell: ensheathment, myelination, trophism and regeneration. Curr. Opin. Neurobiol. 3:805-809.
-
(1993)
Curr. Opin. Neurobiol
, vol.3
, pp. 805-809
-
-
Bunge, R.P.1
-
5
-
-
33750681355
-
The polarity protein Par-3 directly interacts with the p75 neurotrophin receptor to regulate myelination
-
Chan, J.R., C. Jolicoeur, J. Yamauchi, J. Elliott, J.P. Fawcett, B.K. Ng, and M. Cayouette. 2006. The polarity protein Par-3 directly interacts with the p75 neurotrophin receptor to regulate myelination. Science. 314:832-836.
-
(2006)
Science
, vol.314
, pp. 832-836
-
-
Chan, J.R.1
Jolicoeur, C.2
Yamauchi, J.3
Elliott, J.4
Fawcett, J.P.5
Ng, B.K.6
Cayouette, M.7
-
6
-
-
0346037264
-
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins
-
Chang, L., Y. Jones, M.H. Ellisman, L.S. Goldstein, and M. Karin. 2003. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev. Cell. 4:521-533.
-
(2003)
Dev. Cell
, vol.4
, pp. 521-533
-
-
Chang, L.1
Jones, Y.2
Ellisman, M.H.3
Goldstein, L.S.4
Karin, M.5
-
7
-
-
0034282454
-
GTPases and phosphatidylinositol 3-kinase are critical for insulin-like growth factor-I-mediated Schwann cell motility
-
Cheng, H.L., M.L. Steinway, J.W. Russell, and E.L. Feldman. 2000. GTPases and phosphatidylinositol 3-kinase are critical for insulin-like growth factor-I-mediated Schwann cell motility. J. Biol. Chem. 275: 27197-27204.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 27197-27204
-
-
Cheng, H.L.1
Steinway, M.L.2
Russell, J.W.3
Feldman, E.L.4
-
8
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
Citri, A., K.B. Skaria, and Y. Yarden. 2003. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp. Cell Res. 284:54-65.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
9
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Côté, J.F., and K. Vuori. 2002. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115:4901-4913.
-
(2002)
J. Cell Sci
, vol.115
, pp. 4901-4913
-
-
Côté, J.F.1
Vuori, K.2
-
11
-
-
2442664118
-
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
-
Gao, Y., J.B. Dickerson, F. Guo, J. Zheng, and Y. Zheng. 2004. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc. Natl. Acad. Sci. USA. 101:7618-7623.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7618-7623
-
-
Gao, Y.1
Dickerson, J.B.2
Guo, F.3
Zheng, J.4
Zheng, Y.5
-
12
-
-
0033777762
-
Neuregulin, a factor with many functions in the life of a Schwann cell
-
Garratt, A.N., S. Britsch, and C. Birchmeier. 2000. Neuregulin, a factor with many functions in the life of a Schwann cell. Bioessays. 22:987-996.
-
(2000)
Bioessays
, vol.22
, pp. 987-996
-
-
Garratt, A.N.1
Britsch, S.2
Birchmeier, C.3
-
13
-
-
10544248585
-
Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes
-
Grimes, M.L., J. Zhou, E.C. Beattie, E.C. Yuen, D.E. Hall, J.S. Valletta, K.S. Topp, J.H. LaVail, N.W. Bunnett, and W.C. Mobley. 1996. Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes. J. Neurosci. 16:7950-7964.
-
(1996)
J. Neurosci
, vol.16
, pp. 7950-7964
-
-
Grimes, M.L.1
Zhou, J.2
Beattie, E.C.3
Yuen, E.C.4
Hall, D.E.5
Valletta, J.S.6
Topp, K.S.7
LaVail, J.H.8
Bunnett, N.W.9
Mobley, W.C.10
-
14
-
-
0029926307
-
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane
-
Hasegawa, H., E. Kiyokawa, S. Tanaka, K. Nagashima, N. Gotoh, M. Shibuya, T. Kurata, and M. Matsuda. 1996. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol. Cell. Biol. 16:1770-1776.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 1770-1776
-
-
Hasegawa, H.1
Kiyokawa, E.2
Tanaka, S.3
Nagashima, K.4
Gotoh, N.5
Shibuya, M.6
Kurata, T.7
Matsuda, M.8
-
15
-
-
3042689209
-
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
-
Heo, Y.S., S.K. Kim, C.I. Seo, Y.K. Kim, B.J. Sung, H.S. Lee, J.I. Lee, S.Y. Park, J.H. Kim, K.Y. Hwang, et al. 2004. Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. EMBO J. 23:2185-2195.
-
(2004)
EMBO J
, vol.23
, pp. 2185-2195
-
-
Heo, Y.S.1
Kim, S.K.2
Seo, C.I.3
Kim, Y.K.4
Sung, B.J.5
Lee, H.S.6
Lee, J.I.7
Park, S.Y.8
Kim, J.H.9
Hwang, K.Y.10
-
16
-
-
14444288533
-
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
-
Hirose, M., T. Ishizaki, N. Watanabe, M. Uehata, O. Kranenburg, W.H. Moolenaar, F. Matsumura, M. Maekawa, H. Bito, and S. Narumiya. 1998. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J. Cell Biol. 141:1625-1636.
-
(1998)
J. Cell Biol
, vol.141
, pp. 1625-1636
-
-
Hirose, M.1
Ishizaki, T.2
Watanabe, N.3
Uehata, M.4
Kranenburg, O.5
Moolenaar, W.H.6
Matsumura, F.7
Maekawa, M.8
Bito, H.9
Narumiya, S.10
-
17
-
-
0038495741
-
2 003. JNK phosphorylates paxillin and regulates cell migration
-
Huang, C., Z. Rajfur, C. Borchers, M.D. Schaller, and K. J acobson. 2 003. JNK phosphorylates paxillin and regulates cell migration. Nature. 424: 219-223.
-
Nature
, vol.424
, pp. 219-223
-
-
Huang, C.1
Rajfur, Z.2
Borchers, C.3
Schaller, M.D.4
acobson, K.J.5
-
19
-
-
0029054398
-
Glucosylation of Rho proteins by Clostridium difficile toxin B
-
Just, I., J. Selzer, M. Wilm, C. von Eichel-Streiber, M. Mann, and K. Aktories. 1995. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature. 375:500-503.
-
(1995)
Nature
, vol.375
, pp. 500-503
-
-
Just, I.1
Selzer, J.2
Wilm, M.3
von Eichel-Streiber, C.4
Mann, M.5
Aktories, K.6
-
20
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
Katoh, H., and M. Negishi. 2003. RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature. 424:461-464.
-
(2003)
Nature
, vol.424
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
-
21
-
-
0042967835
-
The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
-
Kawauchi, T., K. Chihama, Y. Nabeshima, and M. Hoshino. 2003. The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J. 22:4190-4201.
-
(2003)
EMBO J
, vol.22
, pp. 4190-4201
-
-
Kawauchi, T.1
Chihama, K.2
Nabeshima, Y.3
Hoshino, M.4
-
22
-
-
0029896428
-
Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth
-
Mahanthappa, N.K., E.S. Anton, and W.D. Matthew. 1996. Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth. J. Neurosci. 16:4673-4683.
-
(1996)
J. Neurosci
, vol.16
, pp. 4673-4683
-
-
Mahanthappa, N.K.1
Anton, E.S.2
Matthew, W.D.3
-
23
-
-
0036713381
-
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
-
Meller, N., M. Irani-Tehrani, W.B. Kiosses, M.A. Del Pozo, and M.A. Schwartz. 2002. Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nat. Cell Biol. 4:639-647.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 639-647
-
-
Meller, N.1
Irani-Tehrani, M.2
Kiosses, W.B.3
Del Pozo, M.A.4
Schwartz, M.A.5
-
24
-
-
33749044823
-
Axonal regulation of myelination by neuregulin 1
-
Nave, K.A., and J.L. Salzer. 2006. Axonal regulation of myelination by neuregulin 1. Curr. Opin. Neurobiol. 16:492-500.
-
(2006)
Curr. Opin. Neurobiol
, vol.16
, pp. 492-500
-
-
Nave, K.A.1
Salzer, J.L.2
-
25
-
-
34250740938
-
β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination
-
Nodari, A., D. Zambroni, A. Quattrini, F.A. Court, A. D'Urso, A. Recchia, V.L. Tybulewicz, L. Wrabetz, and M.L. Feltri. 2007. β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination. J. Cell Biol. 177:1063-1075.
-
(2007)
J. Cell Biol
, vol.177
, pp. 1063-1075
-
-
Nodari, A.1
Zambroni, D.2
Quattrini, A.3
Court, F.A.4
D'Urso, A.5
Recchia, A.6
Tybulewicz, V.L.7
Wrabetz, L.8
Feltri, M.L.9
-
26
-
-
0027219258
-
A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
-
Ponzetto, C., A. Bardelli, F. Maina, P. Longati, G. Panayotou, R. Dhand, M.D. Waterfield, and P.M. Comoglio. 1993. A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol. Cell. Biol. 13:4600-4608.
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 4600-4608
-
-
Ponzetto, C.1
Bardelli, A.2
Maina, F.3
Longati, P.4
Panayotou, G.5
Dhand, R.6
Waterfield, M.D.7
Comoglio, P.M.8
-
27
-
-
13444252631
-
-
Rossman, K.L., C.J. Der, and J. Sondek. 2005. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6:167-180.
-
Rossman, K.L., C.J. Der, and J. Sondek. 2005. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6:167-180.
-
-
-
-
28
-
-
0028980059
-
Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development
-
Rushton, E., R. Drysdale, S.M. Abmayr, A.M. Michelson, and M. Bate. 1995. Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development. Development. 121:1979-1988.
-
(1995)
Development
, vol.121
, pp. 1979-1988
-
-
Rushton, E.1
Drysdale, R.2
Abmayr, S.M.3
Michelson, A.M.4
Bate, M.5
-
29
-
-
0036644975
-
Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
-
Schmidt, A., and A. Hall. 2002. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 16:1587-1609.
-
(2002)
Genes Dev
, vol.16
, pp. 1587-1609
-
-
Schmidt, A.1
Hall, A.2
-
30
-
-
0034983715
-
WASP and WAVE family proteins: Key molecules for rapid rearrangement of cortical actin filaments and cell movement
-
Takenawa, T., and H. Miki. 2001. WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement. J. Cell Sci. 114:1801-1809.
-
(2001)
J. Cell Sci
, vol.114
, pp. 1801-1809
-
-
Takenawa, T.1
Miki, H.2
-
31
-
-
0030044628
-
Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells
-
Tsai, C.M., A. Levitzki, L.H. Wu, K.T. Chang, C.C. Cheng, A. Gazit, and R.P. Perng. 1996. Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells. Cancer Res. 56:1068-1074.
-
(1996)
Cancer Res
, vol.56
, pp. 1068-1074
-
-
Tsai, C.M.1
Levitzki, A.2
Wu, L.H.3
Chang, K.T.4
Cheng, C.C.5
Gazit, A.6
Perng, R.P.7
-
32
-
-
33748577718
-
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18
-
Watabe-Uchida, M., K.A. John, J.A. Janas, S.E. Newey, and L. Van Aelst. 2006. The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron. 51:727-739.
-
(2006)
Neuron
, vol.51
, pp. 727-739
-
-
Watabe-Uchida, M.1
John, K.A.2
Janas, J.A.3
Newey, S.E.4
Van Aelst, L.5
-
33
-
-
0032473981
-
-
Wu, Y.C., and H.R. Horvitz. 1998. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature. 392:501-504.
-
Wu, Y.C., and H.R. Horvitz. 1998. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature. 392:501-504.
-
-
-
-
34
-
-
2942535957
-
Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases
-
Yamauchi, J., J.R. Chan, and E.M. Shooter. 2004. Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases. Proc. Natl. Acad. Sci. USA. 101:8774-8779.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8774-8779
-
-
Yamauchi, J.1
Chan, J.R.2
Shooter, E.M.3
-
35
-
-
17044363555
-
The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration
-
Yamauchi, J., J.R. Chan, Y. Miyamoto, G. Tsujimoto, and E.M. Shooter. 2005a. The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration. Proc. Natl. Acad. Sci. USA. 102:5198-5203.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5198-5203
-
-
Yamauchi, J.1
Chan, J.R.2
Miyamoto, Y.3
Tsujimoto, G.4
Shooter, E.M.5
-
36
-
-
26844432744
-
Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3- induced Schwann cell migration
-
Yamauchi, J., Y. Miyamoto, A. Tanoue, E.M. Shooter, and J.R. Chan. 2005b. Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3- induced Schwann cell migration. Proc. Natl. Acad. Sci. USA. 102:14889-14894.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14889-14894
-
-
Yamauchi, J.1
Miyamoto, Y.2
Tanoue, A.3
Shooter, E.M.4
Chan, J.R.5
-
37
-
-
14844293207
-
PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation
-
Zhao, Z.S., and E. Manser. 2005. PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation. Biochem. J. 386:201-214.
-
(2005)
Biochem. J
, vol.386
, pp. 201-214
-
-
Zhao, Z.S.1
Manser, E.2
|