Novel radioiodinated γ-hydroxybutyric acid analogues for radiolabeling and photolinking of high-affinity γ-hydroxybutyric acid binding sites

Journal of Pharmacology and Experimental Therapeutics

Volumn 335, Issue 2, 2010, Pages 458-464

  Wellendorph, Petrine ^a   Høg, Signe ^a   Sabbatini, Paola ^a,d   Pedersen, Martin H F ^b   Martiny, Lars ^b   Knudsen, Gitte M ^c   Frølund, Bente ^a   Clausen, Rasmus P ^a   Bräuner Osborne, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

(6,7,8,9 TETRAHYDRO 5 HYDROXY 5H BENZOCYCLOHEPT 6 YLIDENE)ACETIC ACID H 3; 4 HYDROXY 4 [4 (2 AZIDO 5 IODOBENZYLOXY)PHENYL]BUTANOATE I 125; 4 HYDROXY 4 [4 (2 IODOBENZYLOXY)PHENYL]BUTANOATE I 125; 4 HYDROXYBUTYRIC ACID; IODINE 125; NCS 382; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN SLICE; CEREBELLUM; CORRELATION ANALYSIS; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HIPPOCAMPUS; ISOTOPE LABELING; MALE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN ELECTROPHORESIS; RADIOIODINATION; RAT;

AFFINITY LABELS; ANIMALS; AUTORADIOGRAPHY; AZIDES; BENZOCYCLOHEPTENES; BINDING SITES; BINDING, COMPETITIVE; BRAIN; CELL MEMBRANE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYDROXYBUTYRATES; IODINE RADIOISOTOPES; LIGANDS; MOLECULAR STRUCTURE; PHENYLBUTYRATES; PHOTOAFFINITY LABELS; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA-B;

EID: 78149270040     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.170670     Document Type: Article

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