A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription

Biopolymers

Volumn 95, Issue 1, 2011, Pages 24-30

  Actis, Marcelo ^a   Connelly, Michele C ^a   Mayasundari, Anand ^a   Punchihewa, Chandanamali ^a   Fujii, Naoaki ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Gli1; Hedgehog; Small molecule

Indexed keywords

AMIDE COMPOUNDS; CARBONYL GROUPS; DOWN-STREAM; GLI1; HEDGEHOG; KETOPROFEN; MEDIATED TRANSCRIPTION; SMALL MOLECULES; SMALL-MOLECULE INHIBITORS; STRUCTURE ACTIVITY RELATIONSHIPS;

AMIDES; ETHERS; KETONES; SULFUR COMPOUNDS; TRANSCRIPTION;

MOLECULES;

BENZAMIDE; KETOPROFEN; SULFONAMIDE; SULFONE; TRANSCRIPTION FACTOR GLI1;

ANIMAL CELL; ARTICLE; CANCER CELL; DRUG EFFECT; EMBRYO; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RHABDOMYOMA; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TRANSCRIPTION REGULATION;

BIOPOLYMERS; CELLS, CULTURED; DRUG DESIGN; MOLECULAR STRUCTURE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ERINACEIDAE;

EID: 78049426662     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.21544     Document Type: Article

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