Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment

Journal of Immunology

Volumn 185, Issue 5, 2010, Pages 2867-2876

  Potula, Raghava ^a   Hawkins, Brian J ^a   Cenna, Jonathan M ^a   Fan, Shongshan ^a   Dykstra, Holly ^a   Ramirez, Servio H ^a   Morsey, Brenda ^b   Brodie, Michael R ^b   Persidsky, Yuri ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CALCIUM; CD28 ANTIGEN; INTERLEUKIN 2; METHAMPHETAMINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; CENTRAL STIMULANT AGENT; IMMUNOSUPPRESSIVE AGENT;

ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; DRUG EXPOSURE; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NITROSYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; STIMULATION; T LYMPHOCYTE; CALCIUM SIGNALING; CELL CULTURE; CYTOSOL; DOSE RESPONSE; DRUG EFFECT; ENERGY METABOLISM; FLUORESCENCE MICROSCOPY; IMMUNOLOGY; METABOLISM; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION; UPREGULATION;

CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENERGY METABOLISM; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHAMPHETAMINE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTE SUBSETS; UP-REGULATION;

EID: 78049398990     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903691     Document Type: Article

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