Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 26, 2010, Pages 11775-11780

  Sheftel, Alex D ^a   Stehling, Oliver ^a   Pierik, Antonio J ^a   Elsässer, Hans Peter ^a   Mühlenhoff, Ulrich ^a   Webert, Holger ^a   Hobler, Anna ^b   Hannemann, Frank ^b   Bernhardt, Rita ^b   Lill, Roland ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Adrenodoxin; Cytochrome P450; Iron; Iron sulfur cluster; IRP1

Indexed keywords

CYTOCHROME P450; FERREDOXIN; FERREDOXIN I; IRON; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL PROTEIN FDX2; STEROID; SULFUR; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL METABOLISM; HEME SYNTHESIS; HUMAN; HUMAN CELL; IRON METABOLISM; IRON TRANSPORT; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; STEROIDOGENESIS; YEAST;

ADRENODOXIN; FERREDOXINS; HELA CELLS; HEME; HUMANS; IRON; IRON-SULFUR PROTEINS; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PROTEIN ISOFORMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE PROTEINS; SPECIES SPECIFICITY; STEROIDS;

MAMMALIA;

EID: 77955405138     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004250107     Document Type: Article

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