The conserved Trp155 in human frataxin as a hotspot for oxidative stress related chemical modifications

Biochemical and Biophysical Research Communications

Volumn 390, Issue 3, 2009, Pages 1007-1011

  Correia, Ana R ^a   Ow, Saw Y ^b   Wright, Phillip C ^b   Gomes, Cláudio M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Frataxin; Friedreich's ataxia; Metallochaperone; Oxidative stress; Protein flexibility; Protein folding

Indexed keywords

CHAPERONE; FRATAXIN; REACTIVE OXYGEN METABOLITE; TRYPTOPHAN; TYROSINE;

ARTICLE; BETA SHEET; CARBONYLATION; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; FENTON REACTION; FRIEDREICH ATAXIA; GENE MUTATION; GENETIC CONSERVATION; IRON BINDING CAPACITY; NITRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STABILITY; THERMOSTABILITY;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; HUMANS; IRON-BINDING PROTEINS; NITRITES; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; TRYPTOPHAN;

EID: 70449705810     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.10.095     Document Type: Article

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