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Volumn 54, Issue 3, 2010, Pages 249-258

Molecular imaging of tumor microenvironment: Challenges and perspectives

Author keywords

Extracellular matrix; Matrix metalloproteinases; Molecular imaging

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 2 (N BENZYL 4 METHOXYBENZENESULFONAMIDO) N HYDROXY 3 METHYLBUTANAMIDE; CGS 27023 A; CGS 27023A; COPPER 64; CYCLIN D1; CYTOKINE; FIBROBLAST GROWTH FACTOR; FIBRONECTIN; GADOLINIUM; GELATINASE A; GELATINASE B; GROWTH FACTOR; IODINE 124; MESSENGER RNA; NANOPARTICLE; PROTEINASE; SCATTER FACTOR; SOMATOMEDIN; TRACER; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR;

EID: 77958610812     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (74)
  • 2
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - Bipolar effects of the tumour stroma in cancer
    • Mueller MM, Fusenig NE. Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004;4:839-49.
    • (2004) Nat Rev Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 3
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009;9:239-52.
    • (2009) Nat Rev Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 4
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: Interactions with the tumor stroma
    • doi:10.10l6/j.yexcr.2010.02.045
    • Pietras K, Ostman A. Hallmarks of cancer: Interactions with the tumor stroma. Exp Cell Res 2010; doi:10.10l6/j.yexcr.2010.02.045.
    • (2010) Exp Cell Res
    • Pietras, K.1    Ostman, A.2
  • 5
    • 34848863979 scopus 로고    scopus 로고
    • Impact of the non-cellular tumor microenvironment on metastasis: Potential therapeutic and imaging opportunities
    • Cretu A, Brooks PC. Impact of the non-cellular tumor microenvironment on metastasis: potential therapeutic and imaging opportunities. J Cell Physiol 2007;213:391-402.
    • (2007) J Cell Physiol , vol.213 , pp. 391-402
    • Cretu, A.1    Brooks, P.C.2
  • 7
    • 37549013776 scopus 로고    scopus 로고
    • A microenvironmental model of carcinogenesis
    • Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis. Nat Rev Cancer 2008;8:56-61.
    • (2008) Nat Rev Cancer , vol.8 , pp. 56-61
    • Gatenby, R.A.1    Gillies, R.J.2
  • 8
    • 50149097983 scopus 로고    scopus 로고
    • Hypoxia, HIF1 and glucose metabolism in the solid tumour
    • Denko NC. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer 2008,8:705-13.
    • (2008) Nat Rev Cancer , vol.8 , pp. 705-713
    • Denko, N.C.1
  • 9
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004;4:891-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 11
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009;324:1029-33.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 12
    • 46749121459 scopus 로고    scopus 로고
    • Causes and consequences of increased glucose metabolism of cancers
    • Gillies RJ, Robey I, Gatenby RA. Causes and consequences of increased glucose metabolism of cancers. J Nucl Med 2008;49 Suppl 2-24S-42S.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Gillies, R.J.1    Robey, I.2    Gatenby, R.A.3
  • 13
    • 46749127817 scopus 로고    scopus 로고
    • Tumor cell metabolism imaging
    • Plathow C, Weber WA. Tumor cell metabolism imaging. J Nucl Med 2008;49 Suppl 2:43S-63S.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Plathow, C.1    Weber, W.A.2
  • 14
    • 69249087671 scopus 로고    scopus 로고
    • Environment-mediated drug resistance: A major contributor to minimal residual disease
    • Meads MB, Gatenby RA, Dalton WS. Environment-mediated drug resistance: a major contributor to minimal residual disease. Nat Rev Cancer 2009;9:665-74.
    • (2009) Nat Rev Cancer , vol.9 , pp. 665-674
    • Meads, M.B.1    Gatenby, R.A.2    Dalton, W.S.3
  • 15
    • 0032883946 scopus 로고    scopus 로고
    • Causes and consequences of acidic pH in tumors: A magnetic resonance study
    • Stubbs M, McSheehy PM, Griffiths JR. Causes and consequences of acidic pH in tumors: a magnetic resonance study. Adv Enzyme Regul 1999;39:13-30.
    • (1999) Adv Enzyme Regul , vol.39 , pp. 13-30
    • Stubbs, M.1    McSheehy, P.M.2    Griffiths, J.R.3
  • 17
    • 13944273440 scopus 로고    scopus 로고
    • Imaging hypoxia and angiogenesis in tumors
    • Rajendran JG, Krohn KA. Imaging hypoxia and angiogenesis in tumors. Radiol Clin North Am 2005;43:169-87.
    • (2005) Radiol Clin North Am , vol.43 , pp. 169-187
    • Rajendran, J.G.1    Krohn, K.A.2
  • 19
    • 0020650109 scopus 로고
    • In vivo 31P NMR study of the metabolism of murine mammary 16/C adenocarcinoma and its response to chemotherapy, x-radiation, and hyperthermia
    • Evanochko WT, Ng TC, Lilly MB, Lawson AJ, Corbett TH, Durant JR et al. In vivo 31P NMR study of the metabolism of murine mammary 16/C adenocarcinoma and its response to chemotherapy, x-radiation, and hyperthermia. Proc Natl Acad Sci U S A 1983;80:334-8.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 334-338
    • Evanochko, W.T.1    Ng, T.C.2    Lilly, M.B.3    Lawson, A.J.4    Corbett, T.H.5    Durant, J.R.6
  • 20
    • 0025771650 scopus 로고
    • Are cancer cells acidic?
    • Griffiths JR. Are cancer cells acidic? Br J Cancer 1991;64:425-7.
    • (1991) Br J Cancer , vol.64 , pp. 425-427
    • Griffiths, J.R.1
  • 21
    • 0028465482 scopus 로고
    • 31P-MRS measurements of extra-cellular pH of tumors using 3-aminopropylphosphonate
    • Gillies RJ, Liu Z, Bhujwalla Z. 31P-MRS measurements of extra-cellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol 1994;267:C195-203.
    • (1994) Am J Physiol , vol.267
    • Gillies, R.J.1    Liu, Z.2    Bhujwalla, Z.3
  • 22
    • 0028432597 scopus 로고
    • Imidazol-1-ylalkanoic acids as extrinsic 1H NMR probes for the determination of intracellular pH, extracellular pH and cell volume
    • Gil S, Zaderenzo P, Cruz F, Cerdan S, Ballesteros P. Imidazol-1- ylalkanoic acids as extrinsic 1H NMR probes for the determination of intracellular pH, extracellular pH and cell volume. Bioorg Med Chem 1994;2:305-14.
    • (1994) Bioorg Med Chem , vol.2 , pp. 305-314
    • Gil, S.1    Zaderenzo, P.2    Cruz, F.3    Cerdan, S.4    Ballesteros, P.5
  • 23
    • 0042466426 scopus 로고    scopus 로고
    • Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI
    • Zhou J, Payen JF, Wilson DA, Traystman RJ, van Zijl PC. Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat Med 2003;9:1085-90.
    • (2003) Nat Med , vol.9 , pp. 1085-1090
    • Zhou, J.1    Payen, J.F.2    Wilson, D.A.3    Traystman, R.J.4    Van Zijl, P.C.5
  • 24
    • 0036204319 scopus 로고    scopus 로고
    • Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications
    • Aime S, Barge A, Delli Castelli D, Fedeli F, Mortillaro A, Nielsen FU et al. Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications. Magn Reson Med 2002;47:639-48.
    • (2002) Magn Reson Med , vol.47 , pp. 639-648
    • Aime, S.1    Barge, A.2    Delli Castelli, D.3    Fedeli, F.4    Mortillaro, A.5    Nielsen, F.U.6
  • 29
    • 58149357048 scopus 로고    scopus 로고
    • Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes
    • Urano Y, Asanuma D, Hama Y, Koyama Y, Barrett T, Kamiya M et al. Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med 2009;15:104-9.
    • (2009) Nat Med , vol.15 , pp. 104-109
    • Urano, Y.1    Asanuma, D.2    Hama, Y.3    Koyama, Y.4    Barrett, T.5    Kamiya, M.6
  • 31
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002;2:161-74.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 33
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer C, Tung CH, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001;7:743-8.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3
  • 34
    • 61749094550 scopus 로고    scopus 로고
    • Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon
    • Scherer RL, VanSaun MN, McIntyre JO, Matrisian LM. Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon. Mol Imaging 2008;7:118-31.
    • (2008) Mol Imaging , vol.7 , pp. 118-131
    • Scherer, R.L.1    VanSaun, M.N.2    McIntyre, J.O.3    Matrisian, L.M.4
  • 36
    • 75949098347 scopus 로고    scopus 로고
    • In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer
    • Camb
    • Olson ES, Aguilera TA, Jiang T, Ellies LG, Nguyen QT, Wong EH et al. In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. Integr Biol (Camb) 2009;1:382-93.
    • (2009) Integr Biol , vol.1 , pp. 382-393
    • Olson, E.S.1    Aguilera, T.A.2    Jiang, T.3    Ellies, L.G.4    Nguyen, Q.T.5    Wong, E.H.6
  • 37
    • 34249685936 scopus 로고    scopus 로고
    • A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo
    • Breyholz HJ, Wagner S, Levkau B, Schober O, Schafers M, Kopka K. A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo. Q J Nucl Med Mol Imaging 2007;51:24-32.
    • (2007) Q J Nucl Med Mol Imaging , vol.51 , pp. 24-32
    • Breyholz, H.J.1    Wagner, S.2    Levkau, B.3    Schober, O.4    Schafers, M.5    Kopka, K.6
  • 38
    • 1642451807 scopus 로고    scopus 로고
    • Comparative studies of potential cancer biomarkers carbon-11 labeled MMP inhibitors (S)-2-(4′-[11C]methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid and N-hydroxy-(R)-2-[[(4′-[11C]methoxyphenyl)sulfonyl]benzylamino]- 3-methylbut anamide
    • Zheng QH, Fei X, Liu X, Wang JQ, Stone KL, Martinez TD et al. Comparative studies of potential cancer biomarkers carbon-11 labeled MMP inhibitors (S)-2-(4′-[11C]methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid and N-hydroxy-(R)-2-[[(4′-[11C]methoxyphenyl)sulfonyl]benzylamino] -3-methylbut anamide. Nucl Med Biol 2004;31:77-85.
    • (2004) Nucl Med Biol , vol.31 , pp. 77-85
    • Zheng, Q.H.1    Fei, X.2    Liu, X.3    Wang, J.Q.4    Stone, K.L.5    Martinez, T.D.6
  • 39
    • 12144290444 scopus 로고    scopus 로고
    • Synthesis and preliminary biological evaluation of new radioiodinated MMP inhibitors for imaging MMP activity in vivo
    • Kopka K, Breyholz HJ, Wagner S, Uw MP, Riemann B, Schroer S, et al. Synthesis and preliminary biological evaluation of new radioiodinated MMP inhibitors for imaging MMP activity in vivo. Nucl Med Biol 2004;31:257-67.
    • (2004) Nucl Med Biol , vol.31 , pp. 257-267
    • Kopka, K.1    Breyholz, H.J.2    Wagner, S.3    Uw, M.P.4    Riemann, B.5    Schroer, S.6
  • 40
    • 2642575025 scopus 로고    scopus 로고
    • Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo
    • Schafers M, Riemann B, Kopka K, Breyholz HJ, Wagner S, Schafers KP et al. Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo. Circulation 2004;109:2554-9.
    • (2004) Circulation , vol.109 , pp. 2554-2559
    • Schafers, M.1    Riemann, B.2    Kopka, K.3    Breyholz, H.J.4    Wagner, S.5    Schafers, K.P.6
  • 41
    • 60149095901 scopus 로고    scopus 로고
    • A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: Radiosynthesis and initial small-animal PET studies
    • Wagner S, Breyholz HJ, Holtke C, Faust A, Schober O, Schafers M et al. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Appl Radiat Isot 2009;67:606-10.
    • (2009) Appl Radiat Isot , vol.67 , pp. 606-610
    • Wagner, S.1    Breyholz, H.J.2    Holtke, C.3    Faust, A.4    Schober, O.5    Schafers, M.6
  • 43
    • 37649020428 scopus 로고    scopus 로고
    • Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch
    • Lepage M, Dow WC, Melchior M, You Y, Fingleton B, Quarles CC et al. Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch. Mol Imaging 2007;6:393-403.
    • (2007) Mol Imaging , vol.6 , pp. 393-403
    • Lepage, M.1    Dow, W.C.2    Melchior, M.3    You, Y.4    Fingleton, B.5    Quarles, C.C.6
  • 44
    • 55749111198 scopus 로고    scopus 로고
    • Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model
    • Lebel R, Jastrzebska B, Therriault H, Cournoyer MM, McIntyre JO, Escher E et al. Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model. Magn Reson Med 2008;60:1056-65.
    • (2008) Magn Reson Med , vol.60 , pp. 1056-1065
    • Lebel, R.1    Jastrzebska, B.2    Therriault, H.3    Cournoyer, M.M.4    McIntyre, J.O.5    Escher, E.6
  • 45
    • 77749297971 scopus 로고    scopus 로고
    • Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
    • Olson ES, Jiang T, Aguilera TA, Nguyen QT, Ellies LG, Scadeng M et al. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A 2010; 107:4311-6.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 4311-4316
    • Olson, E.S.1    Jiang, T.2    Aguilera, T.A.3    Nguyen, Q.T.4    Ellies, L.G.5    Scadeng, M.6
  • 46
    • 63849278644 scopus 로고    scopus 로고
    • The urokinase receptor as an entertainer of signal transduction
    • D'Alessio S, Blasi F. The urokinase receptor as an entertainer of signal transduction. Front Biosci 2009;14:4575-87.
    • (2009) Front Biosci , vol.14 , pp. 4575-4587
    • D'Alessio, S.1    Blasi, F.2
  • 48
    • 0027172158 scopus 로고
    • Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: Comparison with urokinase levels
    • Del Vecchio S, Stoppelli MP, Carriero MV, Fonti R, Massa O, Li PY et al. Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: comparison with urokinase levels. Cancer Res 1993;53:3198-206.
    • (1993) Cancer Res , vol.53 , pp. 3198-3206
    • Del Vecchio, S.1    Stoppelli, M.P.2    Carriero, M.V.3    Fonti, R.4    Massa, O.5    Li, P.Y.6
  • 49
    • 0034653737 scopus 로고    scopus 로고
    • Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma
    • Zannetti A, Del Vecchio S, Carriero MV, Fonti R, Franco P, Botti G et al. Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma. Cancer Res 2000;60:1546-51.
    • (2000) Cancer Res , vol.60 , pp. 1546-1551
    • Zannetti, A.1    Del Vecchio, S.2    Carriero, M.V.3    Fonti, R.4    Franco, P.5    Botti, G.6
  • 50
    • 33846978442 scopus 로고    scopus 로고
    • Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
    • Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM et al. Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis. J Clin Oncol 2007;25:349-55.
    • (2007) J Clin Oncol , vol.25 , pp. 349-355
    • Shariat, S.F.1    Roehrborn, C.G.2    McConnell, J.D.3    Park, S.4    Alam, N.5    Wheeler, T.M.6
  • 52
    • 51049094210 scopus 로고    scopus 로고
    • Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET
    • Li ZB, Niu G, Wang H, He L, Yang L, Ploug M et al. Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET. Clin Cancer Res 2008;14:4758-66.
    • (2008) Clin Cancer Res , vol.14 , pp. 4758-4766
    • Li, Z.B.1    Niu, G.2    Wang, H.3    He, L.4    Yang, L.5    Ploug, M.6
  • 53
    • 68049102312 scopus 로고    scopus 로고
    • Receptor-targeted nanoparticles for in vivo imaging of breast cancer
    • Yang L, Peng XH, Wang YA, Wang X, Cao Z, Ni C et al. Receptor-targeted nanoparticles for in vivo imaging of breast cancer. Clin Cancer Res 2009;15:4722-32.
    • (2009) Clin Cancer Res , vol.15 , pp. 4722-4732
    • Yang, L.1    Peng, X.H.2    Wang, Y.A.3    Wang, X.4    Cao, Z.5    Ni, C.6
  • 54
    • 0037314650 scopus 로고    scopus 로고
    • Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer
    • Santimaria M, Moscatelli G, Viale GL, Giovannoni L, Neri G, Viti F et al. Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer. Clin Cancer Res 2003;9:571-9.
    • (2003) Clin Cancer Res , vol.9 , pp. 571-579
    • Santimaria, M.1    Moscatelli, G.2    Viale, G.L.3    Giovannoni, L.4    Neri, G.5    Viti, F.6
  • 55
    • 34250374545 scopus 로고    scopus 로고
    • Imaging of tumor angiogenesis using 99mTc-labeled human recombinant anti-ED-B fibronectin antibody fragments
    • Berndorff D, Borkowski S, Moosmayer D, Viti F, Muller-Tiemann B, Sieger S et al. Imaging of tumor angiogenesis using 99mTc-labeled human recombinant anti-ED-B fibronectin antibody fragments. J Nucl Med 2006;47:1707-16.
    • (2006) J Nucl Med , vol.47 , pp. 1707-1716
    • Berndorff, D.1    Borkowski, S.2    Moosmayer, D.3    Viti, F.4    Muller-Tiemann, B.5    Sieger, S.6
  • 57
    • 34447306888 scopus 로고    scopus 로고
    • Small-animal PET of tumor angiogenesis using a (76)Br-labeled human recombinant antibody fragment to the ED-B domain of fibronectin
    • Rossin R, Berndorff D, Friebe M, Dinkelborg LM, Welch MJ. Small-animal PET of tumor angiogenesis using a (76)Br-labeled human recombinant antibody fragment to the ED-B domain of fibronectin. J Nucl Med 2007;48:1172-9.
    • (2007) J Nucl Med , vol.48 , pp. 1172-1179
    • Rossin, R.1    Berndorff, D.2    Friebe, M.3    Dinkelborg, L.M.4    Welch, M.J.5
  • 58
    • 33749452709 scopus 로고    scopus 로고
    • Tenascin-C induced signaling in cancer
    • Orend G, Chiquet-Ehrismann R. Tenascin-C induced signaling in cancer. Cancer Lett 2006;244:143-63.
    • (2006) Cancer Lett , vol.244 , pp. 143-163
    • Orend, G.1    Chiquet-Ehrismann, R.2
  • 60
    • 0034064244 scopus 로고    scopus 로고
    • Role of nuclear medicine in the treatment of malignant gliomas: The locoregional radioimmunotherapy approach
    • Riva P, Franceschi G, Riva N, Casi M, Santimaria M, Adamo M. Role of nuclear medicine in the treatment of malignant gliomas: the locoregional radioimmunotherapy approach. Eur J Nucl Med 2000;27:601-9.
    • (2000) Eur J Nucl Med , vol.27 , pp. 601-609
    • Riva, P.1    Franceschi, G.2    Riva, N.3    Casi, M.4    Santimaria, M.5    Adamo, M.6
  • 61
    • 23044496421 scopus 로고    scopus 로고
    • Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: A phase II study
    • Akabani G, Reardon DA, Coleman RE, Wong TZ, Metzler SD, Bowsher JE et al. Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study. J Nucl Med 2005;46:1042-51.
    • (2005) J Nucl Med , vol.46 , pp. 1042-1051
    • Akabani, G.1    Reardon, D.A.2    Coleman, R.E.3    Wong, T.Z.4    Metzler, S.D.5    Bowsher, J.E.6
  • 62
    • 37649010802 scopus 로고    scopus 로고
    • Clinical experience with alpha-particle emitting 211At: Treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6
    • Zalutsky MR, Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS et al. Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6. J Nucl Med 2008;49:30-8.
    • (2008) J Nucl Med , vol.49 , pp. 30-38
    • Zalutsky, M.R.1    Reardon, D.A.2    Akabani, G.3    Coleman, R.E.4    Friedman, A.H.5    Friedman, H.S.6
  • 64
    • 33644833474 scopus 로고    scopus 로고
    • Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results
    • Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon JE, 2nd et al. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results. J Clin Oncol 2006;24:115-22.
    • (2006) J Clin Oncol , vol.24 , pp. 115-122
    • Reardon, D.A.1    Akabani, G.2    Coleman, R.E.3    Friedman, A.H.4    Friedman, H.S.5    Herndon II, J.E.6
  • 66
    • 77958531298 scopus 로고    scopus 로고
    • Preclinical molercular imaging of tumor angiogenesis
    • Zhu L, Niu G, Fang X, Chen X. Preclinical molercular imaging of tumor angiogenesis. Q J Nucl Med Mol Imaging 2010;54:291-308.
    • (2010) Q J Nucl Med Mol Imaging , vol.54 , pp. 291-308
    • Zhu, L.1    Niu, G.2    Fang, X.3    Chen, X.4
  • 67
    • 26444571830 scopus 로고    scopus 로고
    • Nuclear imaging of Met-expressing human and canine cancer xenografts with radiolabeled monoclonal antibodies (MetSeek)
    • Hay RV, Cao B, Skinner RS, Su Y, Zhao P, Gustafson MF et al. Nuclear imaging of Met-expressing human and canine cancer xenografts with radiolabeled monoclonal antibodies (MetSeek). Clin Cancer Res 2005;11:7064s-9s.
    • (2005) Clin Cancer Res , vol.11
    • Hay, R.V.1    Cao, B.2    Skinner, R.S.3    Su, Y.4    Zhao, P.5    Gustafson, M.F.6
  • 69
    • 0035875024 scopus 로고    scopus 로고
    • In vivo molecular imaging of met tyrosine kinase growth factor receptor activity in normal organs and breast tumors
    • Shaharabany M, Abramovitch R, Kushnir T, Tsarfaty G, Ravid-Megido M, Horev J et al. In vivo molecular imaging of met tyrosine kinase growth factor receptor activity in normal organs and breast tumors. Cancer Res 2001;61:4873-8.
    • (2001) Cancer Res , vol.61 , pp. 4873-4878
    • Shaharabany, M.1    Abramovitch, R.2    Kushnir, T.3    Tsarfaty, G.4    Ravid-Megido, M.5    Horev, J.6
  • 70
    • 48249128676 scopus 로고    scopus 로고
    • The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of (111)In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin)
    • Cornelissen B, McLarty K, Kersemans V, Reilly RM. The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of (111)In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin). Nucl Med Biol 2008;35:645-53.
    • (2008) Nucl Med Biol , vol.35 , pp. 645-653
    • Cornelissen, B.1    McLarty, K.2    Kersemans, V.3    Reilly, R.M.4
  • 71
    • 35348865605 scopus 로고    scopus 로고
    • PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes
    • Tian X, Aruva MR, Zhang K, Shanthly N, Cardi CA, Thakur ML et al. PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes. J Nucl Med 2007;48:1699-707.
    • (2007) J Nucl Med , vol.48 , pp. 1699-1707
    • Tian, X.1    Aruva, M.R.2    Zhang, K.3    Shanthly, N.4    Cardi, C.A.5    Thakur, M.L.6
  • 72
    • 34748820033 scopus 로고    scopus 로고
    • Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response
    • Koizumi K, Hojo S, Akashi T, Yasumoto K, Saiki I. Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. Cancer Sci 2007;98:1652-8.
    • (2007) Cancer Sci , vol.98 , pp. 1652-1658
    • Koizumi, K.1    Hojo, S.2    Akashi, T.3    Yasumoto, K.4    Saiki, I.5
  • 74
    • 67650033114 scopus 로고    scopus 로고
    • Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT
    • Nimmagadda S, Pullambhatla M, Pomper MG. Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT. J Nucl Med 2009;50:1124-30.
    • (2009) J Nucl Med , vol.50 , pp. 1124-1130
    • Nimmagadda, S.1    Pullambhatla, M.2    Pomper, M.G.3


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