Early events in vascular injury in the rat induced by the phosphodiesterase IV inhibitor SCH 351591

Toxicologic Pathology

Volumn 38, Issue 5, 2010, Pages 738-744

  Weaver, James L ^a   Jun Zhang, ^a   Knapton, Alan ^a   Miller, Terry ^a   Espandiari, Parvaneh ^a   Smith, Roger ^b   Gu, Yi Zhong ^b   Snyder, Ronald D ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

biomarkers.; phosphodiesterase inhibitor; vascular injury

Indexed keywords

HISTAMINE; N (3,5 DICHLORO 1 OXIDO 4 PYRIDINYL) 8 METHOXY 2 TRIFLUOROMETHYL 5 QUINOLINECARBOXAMIDE; NITRIC OXIDE; NITRITE; PHOSPHODIESTERASE IV;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BLOOD VESSEL INJURY; CELL ACTIVATION; CONTROLLED STUDY; GENE EXPRESSION; HISTAMINE BLOOD LEVEL; HISTOPATHOLOGY; LYMPHOCYTE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL MARKERS; CYCLIC N-OXIDES; GENE EXPRESSION; INFLAMMATION; MESENTERY; PHOSPHODIESTERASE 4 INHIBITORS; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; TIME; VASCULAR SYSTEM INJURIES;

RATTUS;

EID: 77958544121     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310374331     Document Type: Article

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