Theophylline-induced mesenteric periarteritis in F344/N rats

Archives of Toxicology

Volumn 72, Issue 11, 1998, Pages 731-737

  Nyska, Abraham ^a   Herbert, Ronald A ^a   Chan, Po C ^a   Haseman, Joseph K ^a   Hailey, James R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alkaloid; Arteritis; Bronchodilator; Pharmaceutical; Theophylline

Indexed keywords

THEOPHYLLINE;

ADVENTITIA; ANIMAL EXPERIMENT; ARTERITIS; ARTICLE; CARCINOGENICITY; DOSE RESPONSE; DRUG EFFECT; FEMALE; INTIMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; ARTERITIS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MESENTERIC ARTERIES; RATS; RATS, INBRED F344; THEOPHYLLINE; TIME FACTORS; VASODILATOR AGENTS;

ANIMALIA; ZEA MAYS;

EID: 0032441236     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050567     Document Type: Article

References (30)

1. Armitage P (1971) Statistical methods in medical research. John Wiley and Sons, New York, pp 362-365
2. Boor PJ, Gotlieb AI, Joseph EC, Kerns WD, Roth RA, Tomaszewski KE (1995) Chemical-induced vascular injury: summary of the symposium presented at the 32nd annual meeting of the Society of Toxicology. New Orleans, Louisiana, March 1993. Toxicol Appl Pharmacol 132: 177-195
3. Bugelski PJ, Vockley CMW, Sowinski JM, Arena E, Berkowitz BA, Morgan DG (1989) Ultrastructure of an arterial lesion induced in rats by fenoldopam mesylate, a dopaminergic vasodilator. Br J Exp Pathol 70: 153-165
4. Carlton WW, Engelhardt JA (1991) Polyarteritis, rat. In: Jones TC, Mohr U, Hunt RD (eds) Cardiovascular and musculoskeletal systems. Springer, Berlin, pp 71-76
5. Clayson DB, Garner RC (1976) Carcinogenic aromatic amines and related compounds. In: Searle CE. (ed) Chemical Carcinogens. American Chemical Society (Monograph 173), Washington, DC, pp 435-436
6. 1 mice. Fundam Appl Toxicol 11: 472-484
7. Cornish HH, Christman AA (1957) A study of the metabolism of theobromine, theophylline and caffeine in man. J Biol Chem 228: 315-323
8. Di Francia M, Barbier D, Mege JL, Orehek J (1994) Tumor necrosis factor-alpha levels and weight loss in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 150: 1453-1455
9. Dinse GE, Haseman JK (1986) Logistic regression analysis of incidental-tumor data from animal carcinogenicity experiments. Fundam Appl Toxicol 6: 44-52
10. Dinse GE, Lagakos SW (1983) Regression analysis of tumour prevalence data. Appl Statist 32: 236-248
11. Gilman AG, Rall TW, Nies AS, Taylor P (1990) (eds) 8th edn. Pergamon Press, New York, pp 589-603
12. Greaves P (1990) Cardiovascular system. In: Histopathology of preclinical toxicity studies: interpretation and relevance in drug safety evaluation. Elsevier Science Publishers, Amsterdam, pp 229-277
13. Grygiel JJ, Birkett DJ (1980) Effect of age on patterns of theophylline metabolism. Clin Pharmacol Ther 28: 456-462
14. Hanton G, Le Net J-L, Ruty B, Leblanc B (1995) Characterization of the arteritis induced by infusion of rats with UK-61,260, an inodilator, for 24 h. Arch Toxicol 69: 698-704
15. Johansson S (1981) Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine. Acta Pathol Microbiol Scand [A] 89: 185-191
16. Joseph EC, Rees JA, Dayan AD (1996) Mesenteric arteriopathy in the rat induced by phosphodiesterase III inhibitors: an investigation of morphological, ultrastructural, and hemodynamic changes. Toxicol Pathol 24: 436-450
17. Kerns WD (1996) Pathogenesis of drug-induced myocardial and arterial lesions: current concepts. Vet Pathol 33: 574 (Abstract)
18. Kerns WD, Arena E, Macia RA, Bugelski PJ, Matthews WD, Morgan DG (1989) Pathogenesis of arterial lesions induced by dopaminergic compounds in the rat. Toxicol Pathol 17: 203-213
19. Kerns WD, Joseph EC, Morgan DG (1991) Drug-induced lesions, arteries, rat. In: Jones TC, Mohr U, Hunt RD (eds) Cardiovascular and musculoskeletal systems. Springer, Berlin, pp 76-83
20. Kodama F, Fukushima K, Umeda M (1980) Chromosome aberrations induced by clinical medicines. J Toxicol Sci 5: 141-150
21. Minton NA, Henry JA (1996) Acute and chronic human toxicity of theophylline. Human Exp Toxicol 15: 471-481
22. Mitsumori K (1990) Blood and lymphatic vessels. In: Boorman GA, Eustis SL, Elwell MR, Montgomery CA, Jr, MacKenzie WF (eds) Pathology of the Fischer rat. Reference and atlas. Academic Press, San Diego, pp 473-484
23. Morgan DG, Bugelski PJ, Berkowitz BA, Valocik RF, Arena EA (1983) Medial necrosis and hemorrhage in rats infused with dopaminergic agents. Lab Invest 48: 60 A (Abstract)
24. Mullick FG, McAllister HA, Wagner BM, Fenoglio JJ (1979) Drug related vasculitis: clinicopathologic correlations in 30 patients. Hum Pathol 10: 313-325
25. National Research Council (1995) Guide for the care and use of laboratory animals. US Government Printing Office, Washington, DC, NIH Publication no. 85-23
26. National Toxicology Program (1998) Toxicology and Carcinogenicity of theophylline (CAS no. 58-55-9) in F344 rats and B6C3F1 mice (feed and gavage studies). NTP Technical Reporting 473, NIH Publication no. 98-3963. National Institute of Environmental Health Sciences Research Triangle Park, N.C.
27. Nordborg C, Fredriksson K, Johansson BB (1985) Internal carotid and vertebral arteries of spontaneously hypertensive and normotensive rats. Acta Pathol Microbiol Immunol Scand [A] 93: 153-158
28. Sandusky GE, Means JR (1987) Acute and subchronic toxicology of LY-195115 in rats and dogs. Toxicol Lett 38: 177-186
29. Semmler J, Gebert U, Eisenhut T, Moeller J, Schönharting MM, Alléra A, Endres S (1993) Xanthine derivatives: comparison between suppression of tumor necrosis factor-α production and inhibition of cAMP phosphodiesterase activity. Immunology 78: 520-525
30. Yuhas EM, Morgan DG, Arena E, Kupp RP, Saunders LZ, Lewis HB (1985) Arterial medial necrosis and hemorrhage induced in rats by intravenous infusion of fenoldopam mesylate, a dopaminergic vasodilator. Am J Pathol 119: 83-91