Synthesis and profile of SCH351591, a novel PDE4 inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 12, 2002, Pages 1621-1623

  Billah, Motasim ^c   Cooper, Nicola ^a   Cuss, Francis ^c   Davenport, Richard J ^a   Dyke, Hazel J ^a   Egan, Robert ^c   Ganguly, Ashit ^c   Gowers, Lewis ^a   Hannah, Duncan R ^a   Haughan, Alan F ^a   Kendall, Hannah J ^a   Lowe, Christopher ^a   Minnicozzi, Michael ^c   Montana, John G ^a   Naylor, Robert ^b   Oxford, Janet ^a   Peake, Joanna C ^a   Piwinski, John J ^c   Runcie, Karen A ^a   Sabin, Verity ^a   Sharpe, Andrew ^a   Shih, Neng Yang ^c   Warneck, Julie B H ^a   more..

^a UCB PHARMA   (Belgium)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; N (3,5 DICHLORO 1 OXIDO 4 PYRIDINYL) 8 METHOXY 2 TRIFLUOROMETHYL 5 QUINOLINECARBOXAMIDE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; QUINOLINE DERIVATIVE; SCH 365351; UNCLASSIFIED DRUG; 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; AMINE OXIDE; PHOSPHODIESTERASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; LOEFFLER PNEUMONIA; NONHUMAN; ANIMAL; AREA UNDER THE CURVE; DRUG ANTAGONISM; SYNTHESIS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMAL; AREA UNDER CURVE; CYCLIC N-OXIDES; GUINEA PIGS; PHOSPHODIESTERASE INHIBITORS; QUINOLINES; ANIMALS;

EID: 0037124189     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00225-1     Document Type: Article

References (11)