Transcriptional Profiling of Laser Capture Microdissected Rat Arterial Elements: Fenoldopam-induced Vascular Toxicity as a Model System

Toxicologic Pathology

Volumn 36, Issue 3, 2008, Pages 496-519

  Dalmas, Deidre A ^a   Scicchitano, Marshall S ^a   Chen, Yifeng ^b   Kane, Janice ^a   Mirabile, Rosanna ^a   Schwartz, Lester W ^a   Thomas, Heath C ^a   Boyce, Rogely W ^a  

^a Department of Safety Assessment ^*  (United States)

^b Discovery Technology   (Finland)

Author keywords

endothelial cells; Fenoldopam; laser capture microdissection; transcriptional profiling; vascular injury; vascular smooth muscle cells

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; FENOLDOPAM; MESSENGER RNA; CASPASE 3;

ANIMAL; ARTERY; ARTICLE; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LASER; MALE; MESENTERY; METABOLISM; METHODOLOGY; MICRODISSECTION; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASCULARIZATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; BLOOD VESSEL INJURY; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE AMPLIFICATION; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LASER CAPTURE MICRODISSECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA ISOLATION; VASCULAR DISEASE;

ANIMALS; ARTERIES; DOPAMINE AGONISTS; ENDOTHELIUM, VASCULAR; FENOLDOPAM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INJECTIONS, SUBCUTANEOUS; LASERS; MALE; MESENTERY; MICRODISSECTION; MUSCLE, SMOOTH, VASCULAR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

ANIMALIA; RATTUS;

EID: 48549090141     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/0192623307311400     Document Type: Article

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