-
1
-
-
34548106014
-
Biphasic modulation of cell proliferation by sulforaphane at physiologically relevant exposure times in a human colon cancer cell line
-
DOI 10.1002/mnfr.200700115
-
Pappa G, Bartsch H and Gerhauser C: Biphasic modulation of cell proliferation by sulforaphane at physiologically relevant exposure times in a human colon cancer cell line. Mol Nutr Food Res 51: 977-984, 2007. (Pubitemid 47292272)
-
(2007)
Molecular Nutrition and Food Research
, vol.51
, Issue.8
, pp. 977-984
-
-
Pappa, G.1
Bartsch, H.2
Gerhauser, C.3
-
2
-
-
33749019130
-
Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma hepg2 cells
-
Keum YS, Yu S, Chang PP, Yuan X, Kim JH, Xu C, Han J, Agarwal A and Kong AN: Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma hepg2 cells. Cancer Res 66: 8804-8813, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 8804-8813
-
-
Keum, Y.S.1
Yu, S.2
Chang, P.P.3
Yuan, X.4
Kim, J.H.5
Xu, C.6
Han, J.7
Agarwal, A.8
Kong, A.N.9
-
3
-
-
0035881570
-
Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines
-
Bonnesen C, Eggleston IM and Hayes JD: Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 61: 6120-6130, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6120-6130
-
-
Bonnesen, C.1
Eggleston, I.M.2
Hayes, J.D.3
-
5
-
-
34248547027
-
Sulforaphane as a promising molecule for fighting cancer
-
Fimognari C and Hrelia P: Sulforaphane as a promising molecule for fighting cancer. Mutat Res 635: 90-104, 2007.
-
(2007)
Mutat Res
, vol.635
, pp. 90-104
-
-
Fimognari, C.1
Hrelia, P.2
-
6
-
-
0031025733
-
Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes
-
Gerhauser C, You M, Liu J, Moriarty RM, Hawthorne M, Mehta RG, Moon RC and Pezzuto JM: Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Res 57: 272-278, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 272-278
-
-
Gerhauser, C.1
You, M.2
Liu, J.3
Moriarty, R.M.4
Hawthorne, M.5
Mehta, R.G.6
Moon, R.C.7
Pezzuto, J.M.8
-
7
-
-
51349088974
-
Multi-targeted prevention of cancer by sulforaphane
-
Clarke JD, Dashwood RH and Ho E: Multi-targeted prevention of cancer by sulforaphane. Cancer Lett 269: 291-304, 2008.
-
(2008)
Cancer Lett
, vol.269
, pp. 291-304
-
-
Clarke, J.D.1
Dashwood, R.H.2
Ho, E.3
-
8
-
-
33749581701
-
+ mice by sulforaphane, a natural product derived from cruciferous vegetable
-
+ mice by sulforaphane, a natural product derived from cruciferous vegetable. Carcinogenesis 27: 2038-2046, 2006.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2038-2046
-
-
Hu, R.1
Khor, T.O.2
Shen, G.3
Jeong, W.S.4
Hebbar, V.5
Chen, C.6
Xu, C.7
Reddy, B.8
Chada, K.9
Kong, A.N.10
-
9
-
-
0028203252
-
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
-
Zhang Y, Kensler TW, Cho CG, Posner GH and Talalay P: Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proc Natl Acad Sci USA 91: 3147-3150, 1994. (Pubitemid 24130192)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.8
, pp. 3147-3150
-
-
Zhang, Y.1
Kensler, T.W.2
Cho, C.-G.3
Posner, G.H.4
Talalay, P.5
-
10
-
-
34247606510
-
Molecular basis for chemoprevention by sulforaphane: A comprehensive review
-
Juge N, Mithen RF and Traka M: Molecular basis for chemoprevention by sulforaphane: A comprehensive review. Cell Mol Life Sci 64: 1105-1127, 2007.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1105-1127
-
-
Juge, N.1
Mithen, R.F.2
Traka, M.3
-
11
-
-
1642545614
-
Sulforaphane induces caspase-mediated apoptosis in cultured pc-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo
-
Singh AV, Xiao D, Lew KL, Dhir R and Singh SV: Sulforaphane induces caspase-mediated apoptosis in cultured pc-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo. Carcinogenesis 25: 83-90, 2004.
-
(2004)
Carcinogenesis
, vol.25
, pp. 83-90
-
-
Singh, A.V.1
Xiao, D.2
Lew, K.L.3
Dhir, R.4
Singh, S.V.5
-
12
-
-
0034162822
-
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells
-
Gamet-Payrastre L, Li P, Lumeau S, Cassar G, Dupont MA, Chevolleau S, Gase N, Tulliez J and Terce F: Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res 60: 1426-1433, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 1426-1433
-
-
Gamet-Payrastre, L.1
Li, P.2
Lumeau, S.3
Cassar, G.4
Dupont, M.A.5
Chevolleau, S.6
Gase, N.7
Tulliez, J.8
Terce, F.9
-
13
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
-
Zhang Y, Talalay P, Cho CG and Posner GH: A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
14
-
-
0029801147
-
Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: A structure-activity relationship study
-
Conaway CC, Jiao D and Chung FL: Inhibition of rat liver cytochrome p450 isozymes by isothiocyanates and their conjugates: A structure activity relationship study. Carcinogenesis 17: 2423-2427, 1996. (Pubitemid 26402242)
-
(1996)
Carcinogenesis
, vol.17
, Issue.11
, pp. 2423-2427
-
-
Conaway, C.C.1
Jiao, D.2
Chung, F.-L.3
-
15
-
-
29144533949
-
Peptide-bond modified glutathione conjugate analogs modulate gstpi function in GSH-conjugation, drug sensitivity and JNK signaling
-
Burg D, Riepsaame J, Pont C, Mulder G and van de Water B: Peptide-bond modified glutathione conjugate analogs modulate gstpi function in GSH-conjugation, drug sensitivity and JNK signaling. Biochem Pharmacol 71: 268-277, 2006.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 268-277
-
-
Burg, D.1
Riepsaame, J.2
Pont, C.3
Mulder, G.4
Van De Water, B.5
-
16
-
-
0028326168
-
Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms
-
Zhang Y and Talalay P: Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms. Cancer Res 54: 1976s-1981s, 1994.
-
(1994)
Cancer Res
, vol.54
-
-
Zhang, Y.1
Talalay, P.2
-
17
-
-
39849092746
-
Sulforaphane and erucin increase MRPl and MRP2 in human carcinoma cell lines
-
Harris KE and Jeffery EH: Sulforaphane and erucin increase MRPl and MRP2 in human carcinoma cell lines. J Nutr Biochem 19: 246-254, 2008.
-
(2008)
J Nutr Biochem
, vol.19
, pp. 246-254
-
-
Harris, K.E.1
Jeffery, E.H.2
-
18
-
-
23344431898
-
Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines
-
Jakubikova J, Bao Y and Sedlak J: Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res 25: 3375-3386, 2005. (Pubitemid 41105214)
-
(2005)
Anticancer Research
, vol.25
, Issue.5
, pp. 3375-3386
-
-
Jakubikova, J.1
Bao, Y.2
Sedlak, J.3
-
19
-
-
67349224103
-
Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells
-
Melchini A, Costa C, Traka M, Miceli N, Mithen R, De Pasquale R and Trovato A: Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem Toxicol 47: 1430-1436, 2009.
-
(2009)
Food Chem Toxicol
, vol.47
, pp. 1430-1436
-
-
Melchini, A.1
Costa, C.2
Traka, M.3
Miceli, N.4
Mithen, R.5
De Pasquale, R.6
Trovato, A.7
-
20
-
-
67651165192
-
D,1-sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
-
Kim SH and Singh SV: D,1-sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther 8: 1946-1954, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1946-1954
-
-
Kim, S.H.1
Singh, S.V.2
-
21
-
-
6344283043
-
Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate
-
Kang YH, Lee E, Choi MK, Ku JL, Kim SH, Park YG and Lim SJ: Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate. Int J Cancer 112: 385-392, 2004.
-
(2004)
Int J Cancer
, vol.112
, pp. 385-392
-
-
Kang, Y.H.1
Lee, E.2
Choi, M.K.3
Ku, J.L.4
Kim, S.H.5
Park, Y.G.6
Lim, S.J.7
-
22
-
-
33745875948
-
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from brassicaceae
-
Pappa G, Lichtenberg M, Iori R, Barillari J, Bartsch H and Gerhauser C: Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from brassicaceae. Mutat Res 599: 76-87, 2006.
-
(2006)
Mutat Res
, vol.599
, pp. 76-87
-
-
Pappa, G.1
Lichtenberg, M.2
Iori, R.3
Barillari, J.4
Bartsch, H.5
Gerhauser, C.6
-
23
-
-
43749092334
-
Intracellular redox status and oxidative stress: Implications for cell proliferation, apoptosis, and carcinogenesis
-
Mates JM, Segura JA, Alonso FJ and Marquez J: Intracellular redox status and oxidative stress: Implications for cell proliferation, apoptosis, and carcinogenesis. Arch Toxicol 82: 273-299, 2008.
-
(2008)
Arch Toxicol
, vol.82
, pp. 273-299
-
-
Mates, J.M.1
Segura, J.A.2
Alonso, F.J.3
Marquez, J.4
-
24
-
-
7444229836
-
The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice
-
Pham NA, Jacobberger JW, Schimmer AD, Cao P, Gronda M and Hedley DW: The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice. Mol Cancer Ther 3: 1239-1248, 2004. (Pubitemid 39440169)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.10
, pp. 1239-1248
-
-
Pham, N.-A.1
Jacobberger, J.W.2
Schimmer, A.D.3
Cao, P.4
Gronda, M.5
Hedley, D.W.6
-
25
-
-
32944475745
-
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (trail)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5
-
Kim H, Kim EH, Eom YW, Kim WH, Kwon TK, Lee SJ and Choi KS: Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (trail)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res 66: 1740-1750, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 1740-1750
-
-
Kim, H.1
Kim, E.H.2
Eom, Y.W.3
Kim, W.H.4
Kwon, T.K.5
Lee, S.J.6
Choi, K.S.7
-
26
-
-
34147135143
-
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
-
Pledgie-Tracy A, Sobolewski MD and Davidson NE: Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther 6: 1013-1021, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1013-1021
-
-
Pledgie-Tracy, A.1
Sobolewski, M.D.2
Davidson, N.E.3
-
27
-
-
10344243477
-
Cancer-preventive isothiocyanates: Dichotomous modulators of oxidative stress
-
DOI 10.1016/j.freeradbiomed.2004.09.033, PII S0891584904008081
-
Zhang Y, Li J and Tang L: Cancer-preventive isothiocyanates: Dichotomous modulators of oxidative stress. Free Radie Biol Med 38: 70-77, 2005. (Pubitemid 39626910)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.1
, pp. 70-77
-
-
Zhang, Y.1
Li, J.2
Tang, L.3
-
28
-
-
77958602983
-
Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism
-
Doudican NA, Bowling B and Orlow SJ: Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism. Leuk Res 2009.
-
(2009)
Leuk Res
-
-
Doudican, N.A.1
Bowling, B.2
Orlow, S.J.3
-
29
-
-
0034019294
-
Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate
-
Murata M, Yamashita N, Inoue S and Kawanishi S: Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate. Free Radic Biol Med 28: 797-805, 2000.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 797-805
-
-
Murata, M.1
Yamashita, N.2
Inoue, S.3
Kawanishi, S.4
-
30
-
-
2942614713
-
2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25c
-
2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25c. J Biol Chem 279: 25813-25822, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 25813-25822
-
-
Singh, S.V.1
Herman-Antosiewicz, A.2
Singh, A.V.3
Lew, K.L.4
Srivastava, S.K.5
Kamath, R.6
Brown, K.D.7
Zhang, L.8
Baskaran, R.9
-
31
-
-
0035451660
-
Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens
-
PII S0027510701001889
-
Steinkellner H, Rabot S, Freywald C, Nobis E, Scharf G, Chabicovsky M, Knasmuller S and Kassie F: Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutat Res 480-481: 285-297, 2001. (Pubitemid 32744835)
-
(2001)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.480-481
, pp. 285-297
-
-
Steinkellner, H.1
Rabot, S.2
Freywald, C.3
Nobis, E.4
Scharf, G.5
Chabicovsky, M.6
Knasmuller, S.7
Kassie, F.8
|