The homeodomain transcription factor Ste12: Connecting fungal MAPK signalling to plant pathogenicity

Communicative and Integrative Biology

Volumn 3, Issue 4, 2010, Pages 327-332

  Rispail, Nicolas ^a,b   Pietro, Antonio Di ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b INSTITUTO DE AGRICULTURA SOSTENIBLE   (Spain)

Author keywords

Fungal pathogenicity; MAPK cascade; Plant pathogen; Signaling; Ste12; Virulence

Indexed keywords

FUNGI;

EID: 77958102243     PISSN: None     EISSN: 19420889     Source Type: Journal    
DOI: 10.4161/cib.3.4.11908     Document Type: Review

References (42)

1. Lee N, D'Souza CA, Kronstad JW. Of smuts, blasts, mildews and blights: cAMP signaling in phytopathogenic fungi. Annu Rev Phytopathol 2003; 41:399-427.
2. Lengeler KB, Davidson RC, D'Souza C, Harashima T, Shen WC, Wang P, et al. Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev 2000; 64:746-85.
3. Rispail N, Soanes DM, Ant C, Czajkowski R, Grunler A, Huguet R, et al. Comparative genomics of MAP kinase and calcium-calcineurin signalling components in plant and human pathogenic fungi. Fungal Genet Biol 2009; 46:287-98.
4. Zhao X, Mehrabi R, Xu JR. Mitogen-activated protein kinase pathways and fungal pathogenesis. Eukaryot Cell 2007; 6:1701-14.
5. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001; 410:37-40.
6. Qi M, Elion EA. MAP kinase pathways. J Cell Sci 2005; 118:3569-72.
7. Xu JR, Hamer JE. MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev 1996; 10:2696-706.
8. Madhani HD, Styles CA, Fink GR. MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 1997; 91:673-84.
9. Wang Y, Dohlman HG. Pheromone signaling mechanisms in yeast: a prototypical sex machine. Science 2004; 306:1508-9.
10. Cullen PJ, Sabbagh W Jr, Graham E, Irick MM, van Olden EK, Neal C, et al. A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 2004; 18:1695-708.
11. Mosch HU, Roberts RL, Fink GR. Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 1996; 93:5352-6.
12. Pryciak PM, Huntress FA. Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway. Genes Dev 1998; 12:2684-97.
13. Elion EA. Routing MAP kinase cascades. Science 1998; 281:1625-6.
14. Madhani HD, Fink GR. Combinatorial control required for the specificity of yeast MAPK signaling. Science 1997; 275:1314-7.
15. Elion EA, Qi M, Chen W. Signal transduction. Signaling specificity in yeast. Science 2005; 307:687-8.
16. Errede B, Ammerer G. STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Genes Dev 1989; 3:1349-61.
17. Chou S, Lane S, Liu H. Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae. Mol Cell Biol 2006; 26:4794-805.
18. Olson KA, Nelson C, Tai G, Hung W, Yong C, Astell C, et al. Two regulators of Ste12p inhibit pheromoneresponsive transcription by separate mechanisms. Mol Cell Biol 2000; 20:4199-209.
19. Kirkman-Correia C, Stroke IL, Fields S. Functional domains of the yeast STE12 protein, a pheromoneresponsive transcriptional activator. Mol Cell Biol 1993; 13:3765-72.
20. Nelson C, Goto S, Lund K, Hung W, Sadowski I. Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12. Nature 2003; 421:187-90.
21. Esch RK, Wang Y, Errede B. Pheromone-induced degradation of Ste12 contributes to signal attenuation and the specificity of developmental fate. Eukaryot Cell 2006; 5:2147-60.
22. Chou S, Zhao S, Song Y, Liu H, Nie Q. Fus3-triggered Tec1 degradation modulates mating transcriptional output during the pheromone response. Mol Syst Biol 2008; 4:212.
23. Delgado-Jarana J, Martinez-Rocha AL, Roldan-Rodriguez R, Roncero MI, Di Pietro A. Fusarium oxysporum G-protein beta subunit Fgb1 regulates hyphal growth, development and virulence through multiple signalling pathways. Fungal Genet Biol 2005; 42:61-72.
24. Di Pietro A, Garcia-MacEira FI, Meglecz E, Roncero MI. A MAP kinase of the vascular wilt fungus Fusarium oxysporum is essential for root penetration and pathogenesis. Mol Microbiol 2001; 39:1140-52.
25. Hoi JW, Herbert C, Bacha N, O'Connell R, Lafitte C, Borderies G, et al. Regulation and role of a STE12-like transcription factor from the plant pathogen Colletotrichum lindemuthianum. Mol Microbiol 2007; 64:68-82.
26. Deng F, Allen TD, Nuss DL. Ste12 transcription factor homologue CpST12 is downregulated by hypovirus infection and required for virulence and female fertility of the chestnut blight fungus Cryphonectria parasitica. Eukaryot Cell 2007; 6:235-44.
27. Schamber A, Leroch M, Diwo J, Mendgen K, Hahn M. The role of mitogen-activated protein (MAP) kinase signalling components and the Ste12 transcription factor in germination and pathogenicity of Botrytis cinerea. Mol Plant Pathol 2010; 11:105-19.
28. Liu H, Kohler J, Fink GR. Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 1994; 266:1723-6.
29. Yue C, Cavallo LM, Alspaugh JA, Wang P, Cox GM, Perfect JR, et al. The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans. Genetics 1999; 153:1601-15.
30. Li D, Bobrowicz P, Wilkinson HH, Ebbole DJ. A mitogen-activated protein kinase pathway essential for mating and contributing to vegetative growth in Neurospora crassa. Genetics 2005; 170:1091-104.
31. +2 finger transcription factor required for sexual reproduction. Mol Microbiol 2000; 36:290-301.
32. Nolting N, Poggeler S. A STE12 homologue of the homothallic ascomycete Sordaria macrospora interacts with the MADS box protein MCM1 and is required for ascosporogenesis. Mol Microbiol 2006; 62:853-68.
33. Kramer B, Thines E, Foster AJ. MAP kinase signalling pathway components and targets conserved between the distantly related plant pathogenic fungi Mycosphaerella graminicola and Magnaporthe grisea. Fungal Genet Biol 2009; 46:667-81.
34. Wong Sak Hoi J, Dumas B. The STE12 and STE12-like proteins: fungal transcription factors regulating development and pathogenicity. Eukaryot Cell 2010.
35. Park G, Xue C, Zheng L, Lam S, Xu JR. MST12 regulates infectious growth but not appressorium formation in the rice blast fungus Magnaporthe grisea. Mol Plant Microbe Interact 2002; 15:183-92.
36. Rispail N, Di Pietro A. Fusarium oxysporum Ste12 controls invasive growth and virulence downstream of the Fmk1 MAPK cascade. Mol Plant Microbe Interact 2009; 22:830-9.
37. Tsuji G, Fujii S, Tsuge S, Shiraishi T, Kubo Y. The Colletotrichum lagenarium Ste12-like gene CST1 is essential for appressorium penetration. Mol Plant Microbe Interact 2003; 16:315-25.
38. Garcia-Sanchez AM, Martin-Rodrigues N, Ramos B, de Vega-Bartol JJ, Perlin MH, Diaz-Minguez JM. fost12, the Fusarium oxysporum homolog of the transcription factor Ste12, is upregulated during plant infection and required for virulence. Fungal Genet Biol 2010; 47:216-25.
39. Park G, Bruno KS, Staiger CJ, Talbot NJ, Xu JR. Independent genetic mechanisms mediate turgor generation and penetration peg formation during plant infection in the rice blast fungus. Mol Microbiol 2004; 53:1695-707.
40. Pi H, Chien CT, Fields S. Transcriptional activation upon pheromone stimulation mediated by small domain of Saccharomyces cerevisiae Ste12p. Mol Cell Biol 1997; 17:6410-8.
41. Madhani HD, Galitski T, Lander ES, Fink GR. Effectors of a developmental mitogen-activated protein kinase cascade revealed by expression signatures of signaling mutants. Proc Natl Acad Sci USA 1999; 96:12530-5.
42. Zeitlinger J, Simon I, Harbison CT, Hannett NM, Volkert TL, Fink GR, et al. Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling. Cell 2003; 113:395-404.