메뉴 건너뛰기




Volumn 6, Issue 8, 2010, Pages 45-46

Functional characterisation and drug target validation of a mitotic kinesin-13 in Trypanosoma brucei

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; PROTEIN TBKIF13 1; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; PROTOZOAL PROTEIN;

EID: 77958084230     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001050     Document Type: Article
Times cited : (33)

References (77)
  • 1
    • 40849096098 scopus 로고    scopus 로고
    • Implications of the new eukaryotic systematics for parasitologists
    • Dacks JB, Walker G, Field MC (2008) Implications of the new eukaryotic systematics for parasitologists. Parasitol Int 57: 97-104.
    • (2008) Parasitol Int , vol.57 , pp. 97-104
    • Dacks, J.B.1    Walker, G.2    Field, M.C.3
  • 2
    • 0032724638 scopus 로고    scopus 로고
    • The cytoskeleton of trypanosomatid parasites
    • Gull K (1999) The cytoskeleton of trypanosomatid parasites. Annu Rev Microbiol 53: 629-655.
    • (1999) Annu Rev Microbiol , vol.53 , pp. 629-655
    • Gull, K.1
  • 3
    • 0034871528 scopus 로고    scopus 로고
    • The extended tubulin superfamily
    • McKean PG, Vaughan S, Gull K (2001) The extended tubulin superfamily. J Cell Sci 114: 2723-2733.
    • (2001) J Cell Sci , vol.114 , pp. 2723-2733
    • McKean, P.G.1    Vaughan, S.2    Gull, K.3
  • 4
    • 30544436017 scopus 로고    scopus 로고
    • The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis
    • Dawe HR, Farr H, Portman N, Shaw MK, Gull K (2005) The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis. J Cell Sci.
    • (2005) J Cell Sci
    • Dawe, H.R.1    Farr, H.2    Portman, N.3    Shaw, M.K.4    Gull, K.5
  • 5
    • 35748935579 scopus 로고    scopus 로고
    • The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules
    • Dawe HR, Shaw MK, Farr H, Gull K (2007) The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules. BMC Biol 5: 33.
    • (2007) BMC Biol , vol.5 , pp. 33
    • Dawe, H.R.1    Shaw, M.K.2    Farr, H.3    Gull, K.4
  • 6
    • 54149116728 scopus 로고    scopus 로고
    • Swimming with protists: Perception, motility and flagellum assembly
    • Ginger ML, Portman N, McKean PG (2008) Swimming with protists: perception, motility and flagellum assembly. Nat Rev Microbiol 6: 838-850.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 838-850
    • Ginger, M.L.1    Portman, N.2    McKean, P.G.3
  • 7
    • 17644379059 scopus 로고    scopus 로고
    • An Evolutionarily Conserved Coiled-Coil Protein Implicated in Polycystic Kidney Disease Is Involved in Basal Body Duplication and Flagellar Biogenesis in Trypanosoma brucei
    • Morgan GW, Denny PW, Vaughan S, Goulding D, Jeffries TR, et al. (2005) An Evolutionarily Conserved Coiled-Coil Protein Implicated in Polycystic Kidney Disease Is Involved in Basal Body Duplication and Flagellar Biogenesis in Trypanosoma brucei. Mol Cell Biol 25: 3774-3783.
    • (2005) Mol Cell Biol , vol.25 , pp. 3774-3783
    • Morgan, G.W.1    Denny, P.W.2    Vaughan, S.3    Goulding, D.4    Jeffries, T.R.5
  • 8
    • 33644858832 scopus 로고    scopus 로고
    • Flagellar motility is required for the viability of the bloodstream trypanosome
    • Broadhead R, Dawe HR, Farr H, Griffiths S, Hart SR, et al. (2006) Flagellar motility is required for the viability of the bloodstream trypanosome. Nature 440: 224-227.
    • (2006) Nature , vol.440 , pp. 224-227
    • Broadhead, R.1    Dawe, H.R.2    Farr, H.3    Griffiths, S.4    Hart, S.R.5
  • 9
    • 71449084986 scopus 로고    scopus 로고
    • Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia
    • Duquesnoy P, Escudier E, Vincensini L, Freshour J, Bridoux AM, et al. (2009) Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia. Am J Hum Genet 85: 890-896.
    • (2009) Am J Hum Genet , vol.85 , pp. 890-896
    • Duquesnoy, P.1    Escudier, E.2    Vincensini, L.3    Freshour, J.4    Bridoux, A.M.5
  • 11
    • 33645757529 scopus 로고    scopus 로고
    • Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes
    • Richardson DN, Simmons MP, Reddy AS (2006) Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes. BMC Genomics 7: 18.
    • (2006) BMC Genomics , vol.7 , pp. 18
    • Richardson, D.N.1    Simmons, M.P.2    Reddy, A.S.3
  • 12
    • 33745338902 scopus 로고    scopus 로고
    • A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions
    • Wickstead B, Gull K (2006) A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions. Mol Biol Cell 17: 1734-1743.
    • (2006) Mol Biol Cell , vol.17 , pp. 1734-1743
    • Wickstead, B.1    Gull, K.2
  • 14
    • 0034496239 scopus 로고    scopus 로고
    • Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells
    • Weise F, Stierhof YD, Kuhn C, Wiese M, Overath P (2000) Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells. J Cell Sci 113 Pt 24: 4587-4603.
    • (2000) J Cell Sci 113 Pt , vol.24 , pp. 4587-4603
    • Weise, F.1    Stierhof, Y.D.2    Kuhn, C.3    Wiese, M.4    Overath, P.5
  • 15
    • 0014755202 scopus 로고
    • Spindle microtubules in the dividing nuclei of trypanosomes
    • Vickerman K, Preston TM (1970) Spindle microtubules in the dividing nuclei of trypanosomes. J Cell Science 6: 365-383.
    • (1970) J Cell Science , vol.6 , pp. 365-383
    • Vickerman, K.1    Preston, T.M.2
  • 17
    • 0034007354 scopus 로고    scopus 로고
    • Architecture of the Trypanosoma brucei nucleus during interphase and mitosis
    • Ogbadoyi E, Ersfeld K, Robinson D, Sherwin T, Gull K (2000) Architecture of the Trypanosoma brucei nucleus during interphase and mitosis. Chromosoma 108: 501-513.
    • (2000) Chromosoma , vol.108 , pp. 501-513
    • Ogbadoyi, E.1    Ersfeld, K.2    Robinson, D.3    Sherwin, T.4    Gull, K.5
  • 18
    • 0000060704 scopus 로고    scopus 로고
    • Nuclear and genome organization of Trypanosoma brucei
    • Ersfeld K, Melville SE, Gull K (1999) Nuclear and genome organization of Trypanosoma brucei. Parasitol Today 15: 58-63.
    • (1999) Parasitol Today , vol.15 , pp. 58-63
    • Ersfeld, K.1    Melville, S.E.2    Gull, K.3
  • 19
    • 0031719714 scopus 로고    scopus 로고
    • Segregation of minichromosomes in trypanosomes: Implications for mitotic mechanisms
    • Gull K, Alsford S, Ersfeld K (1998) Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms. Trends Microbiol 6: 319-323.
    • (1998) Trends Microbiol , vol.6 , pp. 319-323
    • Gull, K.1    Alsford, S.2    Ersfeld, K.3
  • 21
    • 24344465919 scopus 로고    scopus 로고
    • Analysis of the kinesin superfamily: Insights into structure and function
    • Miki H, Okada Y, Hirokawa N (2005) Analysis of the kinesin superfamily: insights into structure and function. Trends Cell Biol 15: 467-476.
    • (2005) Trends Cell Biol , vol.15 , pp. 467-476
    • Miki, H.1    Okada, Y.2    Hirokawa, N.3
  • 23
    • 0028245510 scopus 로고
    • Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends
    • Endow SA, Kang SJ, Satterwhite LL, Rose MD, Skeen VP, et al. (1994) Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. Embo J 13: 2708-2713.
    • (1994) Embo J , vol.13 , pp. 2708-2713
    • Endow, S.A.1    Kang, S.J.2    Satterwhite, L.L.3    Rose, M.D.4    Skeen, V.P.5
  • 25
    • 4143075910 scopus 로고    scopus 로고
    • The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK
    • Ganem NJ, Compton DA (2004) The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. J Cell Biol 166: 473-478.
    • (2004) J Cell Biol , vol.166 , pp. 473-478
    • Ganem, N.J.1    Compton, D.A.2
  • 26
    • 34547726131 scopus 로고    scopus 로고
    • The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells
    • Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, et al. (2007) The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol Biol Cell 18: 2970-2979.
    • (2007) Mol Biol Cell , vol.18 , pp. 2970-2979
    • Manning, A.L.1    Ganem, N.J.2    Bakhoum, S.F.3    Wagenbach, M.4    Wordeman, L.5
  • 27
    • 0043199576 scopus 로고    scopus 로고
    • Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension
    • Homma N, Takei Y, Tanaka Y, Nakata T, Terada S, et al. (2003) Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell 114: 229-239.
    • (2003) Cell , vol.114 , pp. 229-239
    • Homma, N.1    Takei, Y.2    Tanaka, Y.3    Nakata, T.4    Terada, S.5
  • 28
    • 34548814434 scopus 로고    scopus 로고
    • Mitotic drug targets and the development of novel anti-mitotic anticancer drugs
    • Schmidt M, Bastians H (2007) Mitotic drug targets and the development of novel anti-mitotic anticancer drugs. Drug Resist Updat 10: 162-181.
    • (2007) Drug Resist Updat , vol.10 , pp. 162-181
    • Schmidt, M.1    Bastians, H.2
  • 29
    • 17144405643 scopus 로고    scopus 로고
    • Mitotic kinesins: Prospects for antimitotic drug discovery
    • Bergnes G, Brejc K, Belmont L (2005) Mitotic kinesins: prospects for antimitotic drug discovery. Curr Top Med Chem 5: 127-145.
    • (2005) Curr Top Med Chem , vol.5 , pp. 127-145
    • Bergnes, G.1    Brejc, K.2    Belmont, L.3
  • 30
    • 42549084401 scopus 로고    scopus 로고
    • A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: A study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)
    • Knox JJ, Gill S, Synold TW, Biagi JJ, Major P, et al. (2008) A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168). Invest New Drugs.
    • (2008) Invest New Drugs
    • Knox, J.J.1    Gill, S.2    Synold, T.W.3    Biagi, J.J.4    Major, P.5
  • 31
    • 74549223522 scopus 로고    scopus 로고
    • Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer
    • Purcell JW, Davis J, Reddy M, Martin S, Samayoa K, et al. (2010) Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer. Clin Cancer Res 16: 566-576.
    • (2010) Clin Cancer Res , vol.16 , pp. 566-576
    • Purcell, J.W.1    Davis, J.2    Reddy, M.3    Martin, S.4    Samayoa, K.5
  • 32
    • 34247515617 scopus 로고    scopus 로고
    • A novel microtubule-depolymerizing kinesin involved in length control of a eukaryotic flagellum
    • Blaineau C, Tessier M, Dubessay P, Tasse L, Crobu L, et al. (2007) A novel microtubule-depolymerizing kinesin involved in length control of a eukaryotic flagellum. Curr Biol 17: 778-782.
    • (2007) Curr Biol , vol.17 , pp. 778-782
    • Blaineau, C.1    Tessier, M.2    Dubessay, P.3    Tasse, L.4    Crobu, L.5
  • 33
    • 33645053253 scopus 로고    scopus 로고
    • Cell cycle- dependent expression regulation by the proteasome pathway and characteriza- tion of the nuclear targeting signal of a Leishmania major Kin-13 kinesin
    • Dubessay P, Blaineau C, Bastien P, Tasse L, Van Dijk J, et al. (2006) Cell cycle- dependent expression regulation by the proteasome pathway and characteriza- tion of the nuclear targeting signal of a Leishmania major Kin-13 kinesin. Mol Microbiol 59: 1162-1174.
    • (2006) Mol Microbiol , vol.59 , pp. 1162-1174
    • Dubessay, P.1    Blaineau, C.2    Bastien, P.3    Tasse, L.4    van Dijk, J.5
  • 34
    • 46949084398 scopus 로고    scopus 로고
    • Functional characterisation of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages
    • Gluenz E, Sharma R, Carrington M, Gull K (2008) Functional characterisation of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages. Mol Microbiol.
    • (2008) Mol Microbiol
    • Gluenz, E.1    Sharma, R.2    Carrington, M.3    Gull, K.4
  • 35
    • 0033398908 scopus 로고    scopus 로고
    • Evidence for novel cell cycle checkpoints in trypanosomes: Kinetoplast segregation and cytokinesis in the absence of mitosis
    • Ploubidou A, Robinson DR, Docherty RC, Ogbadoyi EO, Gull K (1999) Evidence for novel cell cycle checkpoints in trypanosomes: kinetoplast segregation and cytokinesis in the absence of mitosis. J Cell Sci 112 (Pt 24): 4641-4650.
    • (1999) J Cell Sci , vol.112 , Issue.Pt 24 , pp. 4641-4650
    • Ploubidou, A.1    Robinson, D.R.2    Docherty, R.C.3    Ogbadoyi, E.O.4    Gull, K.5
  • 36
    • 30944445981 scopus 로고    scopus 로고
    • Dissociation of cytokinesis initiation from mitotic control in a eukaryote
    • Kumar P, Wang CC (2006) Dissociation of cytokinesis initiation from mitotic control in a eukaryote. Eukaryot Cell 5: 92-102.
    • (2006) Eukaryot Cell , vol.5 , pp. 92-102
    • Kumar, P.1    Wang, C.C.2
  • 37
    • 0024065220 scopus 로고
    • Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei
    • Sasse R, Gull K (1988) Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei. J Cell Sci 90 (Pt 4): 577-589.
    • (1988) J Cell Sci , vol.90 , Issue.Pt 4 , pp. 577-589
    • Sasse, R.1    Gull, K.2
  • 38
    • 48649087988 scopus 로고    scopus 로고
    • Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei
    • Li Z, Lee JH, Chu F, Burlingame AL, Gunzl A, et al. (2008) Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei. PLoS ONE 3: e2354.
    • (2008) PLoS ONE , vol.e2354 , pp. 3
    • Li, Z.1    Lee, J.H.2    Chu, F.3    Burlingame, A.L.4    Gunzl, A.5
  • 39
    • 56849098438 scopus 로고    scopus 로고
    • The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like kinase in trypanosomes to regulate mitosis and cytokinesis
    • Li Z, Umeyama T, Wang CC (2008) The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like kinase in trypanosomes to regulate mitosis and cytokinesis. PLoS ONE 3: e3814.
    • (2008) PLoS ONE , vol.e3814 , pp. 3
    • Li, Z.1    Umeyama, T.2    Wang, C.C.3
  • 40
    • 2342565893 scopus 로고    scopus 로고
    • Structure of a kinesin microtubule depolymerization machine
    • Shipley K, Hekmat-Nejad M, Turner J, Moores C, Anderson R, et al. (2004) Structure of a kinesin microtubule depolymerization machine. Embo J 23: 1422-1432.
    • (2004) Embo J , vol.23 , pp. 1422-1432
    • Shipley, K.1    Hekmat-Nejad, M.2    Turner, J.3    Moores, C.4    Anderson, R.5
  • 42
    • 0034695259 scopus 로고    scopus 로고
    • 15 A resolution model of the monomeric kinesin motor, KIF1A
    • Kikkawa M, Okada Y, Hirokawa N (2000) 15 A resolution model of the monomeric kinesin motor, KIF1A. Cell 100: 241-252.
    • (2000) Cell , vol.100 , pp. 241-252
    • Kikkawa, M.1    Okada, Y.2    Hirokawa, N.3
  • 43
    • 0035966079 scopus 로고    scopus 로고
    • A novel C- terminal kinesin is essential for maintaining functional acidocalcisomes in Trypanosoma brucei
    • Dutoya S, Gibert S, Lemercier G, Santarelli X, Baltz D, et al. (2001) A novel C- terminal kinesin is essential for maintaining functional acidocalcisomes in Trypanosoma brucei. J Biol Chem 276: 49117-49124.
    • (2001) J Biol Chem , vol.276 , pp. 49117-49124
    • Dutoya, S.1    Gibert, S.2    Lemercier, G.3    Santarelli, X.4    Baltz, D.5
  • 44
    • 65249162890 scopus 로고    scopus 로고
    • Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules
    • Cai S, Weaver LN, Ems-McClung SC, Walczak CE (2009) Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules. Mol Biol Cell 20: 1348-1359.
    • (2009) Mol Biol Cell , vol.20 , pp. 1348-1359
    • Cai, S.1    Weaver, L.N.2    Ems-McClung, S.C.3    Walczak, C.E.4
  • 45
    • 31944445529 scopus 로고    scopus 로고
    • Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK
    • Hertzer KM, Ems-McClung SC, Kline-Smith SL, Lipkin TG, Gilbert SP, et al. (2006) Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK. Mol Biol Cell 17: 700-710.
    • (2006) Mol Biol Cell , vol.17 , pp. 700-710
    • Hertzer, K.M.1    Ems-McClung, S.C.2    Kline-Smith, S.L.3    Lipkin, T.G.4    Gilbert, S.P.5
  • 46
    • 2342565893 scopus 로고    scopus 로고
    • Structure of a kinesin microtubule depolymerization machine
    • Shipley K, Hekmat-Nejad M, Turner J, Moores C, Anderson R, et al. (2004) Structure of a kinesin microtubule depolymerization machine. EMBO J 23: 1422-1432.
    • (2004) EMBO J , vol.23 , pp. 1422-1432
    • Shipley, K.1    Hekmat-Nejad, M.2    Turner, J.3    Moores, C.4    Anderson, R.5
  • 47
    • 33748598232 scopus 로고    scopus 로고
    • Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote
    • Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, et al. (2006) Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol 4: e286.
    • (2006) PLoS Biol , vol.e286 , pp. 4
    • Eisen, J.A.1    Coyne, R.S.2    Wu, M.3    Wu, D.4    Thiagarajan, M.5
  • 48
    • 33748158378 scopus 로고    scopus 로고
    • Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle
    • Gupta ML, Jr., Carvalho P, Roof DM, Pellman D (2006) Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle. Nat Cell Biol 8: 913-923.
    • (2006) Nat Cell Biol , vol.8 , pp. 913-923
    • Gupta Jr., M.L.1    Carvalho, P.2    Roof, D.M.3    Pellman, D.4
  • 49
    • 37549037135 scopus 로고    scopus 로고
    • Kinesin-13 regulates flagellar, interphase, and mitotic microtubule dynamics in Giardia intestinalis
    • Dawson SC, Sagolla MS, Mancuso JJ, Woessner DJ, House SA, et al. (2007) Kinesin-13 regulates flagellar, interphase, and mitotic microtubule dynamics in Giardia intestinalis. Eukaryot Cell.
    • (2007) Eukaryot Cell
    • Dawson, S.C.1    Sagolla, M.S.2    Mancuso, J.J.3    Woessner, D.J.4    House, S.A.5
  • 50
    • 63849291991 scopus 로고    scopus 로고
    • A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas
    • Piao T, Luo M, Wang L, Guo Y, Li D, et al. (2009) A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas. Proc Natl Acad Sci U S A 106: 4713-4718.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4713-4718
    • Piao, T.1    Luo, M.2    Wang, L.3    Guo, Y.4    Li, D.5
  • 51
    • 16644375282 scopus 로고    scopus 로고
    • Cytoskeletal motors in Arabidopsis. Sixty-one kinesins and seventeen myosins
    • Lee YR, Liu B (2004) Cytoskeletal motors in Arabidopsis. Sixty-one kinesins and seventeen myosins. Plant Physiol 136: 3877-3883.
    • (2004) Plant Physiol , vol.136 , pp. 3877-3883
    • Lee, Y.R.1    Liu, B.2
  • 52
    • 12844281650 scopus 로고    scopus 로고
    • An internal motor kinesin is associated with the Golgi apparatus and plays a role in trichome morphogenesis in Arabidopsis
    • Lu L, Lee YR, Pan R, Maloof JN, Liu B (2005) An internal motor kinesin is associated with the Golgi apparatus and plays a role in trichome morphogenesis in Arabidopsis. Mol Biol Cell 16: 811-823.
    • (2005) Mol Biol Cell , vol.16 , pp. 811-823
    • Lu, L.1    Lee, Y.R.2    Pan, R.3    Maloof, J.N.4    Liu, B.5
  • 53
    • 0029353950 scopus 로고
    • Mitosis and genome partitioning in trypanosomes
    • Solari AJ (1995) Mitosis and genome partitioning in trypanosomes. BIOCELL 19: 65-84.
    • (1995) BIOCELL , vol.19 , pp. 65-84
    • Solari, A.J.1
  • 54
    • 1642540211 scopus 로고    scopus 로고
    • Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase
    • Rogers GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, et al. (2004) Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature 427: 364-370.
    • (2004) Nature , vol.427 , pp. 364-370
    • Rogers, G.C.1    Rogers, S.L.2    Schwimmer, T.A.3    Ems-McClung, S.C.4    Walczak, C.E.5
  • 55
    • 0030031999 scopus 로고    scopus 로고
    • XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
    • Walczak CE, Mitchison TJ, Desai A (1996) XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell 84: 37-47.
    • (1996) Cell , vol.84 , pp. 37-47
    • Walczak, C.E.1    Mitchison, T.J.2    Desai, A.3
  • 56
    • 0030481488 scopus 로고    scopus 로고
    • Alpha-Tubulin limits its own synthesis: Evidence for a mechanism involving translational repression
    • Gonzalez-Garay ML, Cabral F (1996) alpha-Tubulin limits its own synthesis: evidence for a mechanism involving translational repression. J Cell Biol 135: 1525-1534.
    • (1996) J Cell Biol , vol.135 , pp. 1525-1534
    • Gonzalez-Garay, M.L.1    Cabral, F.2
  • 57
    • 0023634247 scopus 로고
    • Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs
    • Pachter JS, Yen TJ, Cleveland DW (1987) Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs. Cell 51: 283-292.
    • (1987) Cell , vol.51 , pp. 283-292
    • Pachter, J.S.1    Yen, T.J.2    Cleveland, D.W.3
  • 58
    • 77949540170 scopus 로고    scopus 로고
    • How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays
    • in press
    • Wordeman L (2010) How kinesin motor proteins drive mitotic spindle function: lessons from molecular assays. Sem Cell Dev Biolcolon; in press.
    • (2010) Sem Cell Dev Biolcolon
    • Wordeman, L.1
  • 59
    • 0141768258 scopus 로고    scopus 로고
    • The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line
    • Goshima G, Vale RD (2003) The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol 162: 1003-1016.
    • (2003) J Cell Biol , vol.162 , pp. 1003-1016
    • Goshima, G.1    Vale, R.D.2
  • 60
    • 14744287039 scopus 로고    scopus 로고
    • Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase
    • Mennella V, Rogers GC, Rogers SL, Buster DW, Vale RD, et al. (2005) Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nat Cell Biol.
    • (2005) Nat Cell Biol
    • Mennella, V.1    Rogers, G.C.2    Rogers, S.L.3    Buster, D.W.4    Vale, R.D.5
  • 61
  • 62
    • 77951836629 scopus 로고    scopus 로고
    • Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14
    • Hentrich C, Surrey T (2010) Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14. The Journal of Cell Biology 189: 465-480.
    • (2010) The Journal of Cell Biology , vol.189 , pp. 465-480
    • Hentrich, C.1    Surrey, T.2
  • 63
    • 0033534575 scopus 로고    scopus 로고
    • Kin I kinesins are microtubule-destabilizing enzymes
    • Desai A, Verma S, Mitchison TJ, Walczak CE (1999) Kin I kinesins are microtubule-destabilizing enzymes. Cell 96: 69-78.
    • (1999) Cell , vol.96 , pp. 69-78
    • Desai, A.1    Verma, S.2    Mitchison, T.J.3    Walczak, C.E.4
  • 64
    • 0036242697 scopus 로고    scopus 로고
    • A mechanism for microtubule depolymerization by KinI kinesins
    • Moores CA, Yu M, Guo J, Beraud C, Sakowicz R, et al. (2002) A mechanism for microtubule depolymerization by KinI kinesins. Mol Cell 9: 903-909.
    • (2002) Mol Cell , vol.9 , pp. 903-909
    • Moores, C.A.1    Yu, M.2    Guo, J.3    Beraud, C.4    Sakowicz, R.5
  • 65
    • 0024948840 scopus 로고
    • Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
    • Hirumi H, Hirumi K (1989) Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J Parasitol 75: 985-989.
    • (1989) J Parasitol , vol.75 , pp. 985-989
    • Hirumi, H.1    Hirumi, K.2
  • 66
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz E, Leal S, Ochatt C, Cross GA (1999) A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol 99: 89-101.
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.4
  • 67
    • 0018601361 scopus 로고
    • Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Shortcommunication
    • Brun R, Schonenburger M (1979) Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Shortcommunication. Acta Trop 36: 289-292.
    • (1979) Acta Trop , vol.36 , pp. 289-292
    • Brun, R.1    Schonenburger, M.2
  • 68
    • 0037031944 scopus 로고    scopus 로고
    • Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei
    • Bochud-Allemann N, Schneider A (2002) Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei. J Biol Chem 277: 32849-32854.
    • (2002) J Biol Chem , vol.277 , pp. 32849-32854
    • Bochud-Allemann, N.1    Schneider, A.2
  • 69
    • 0037466382 scopus 로고    scopus 로고
    • RNAit: An automated web-based tool for the selection of RNAi targets in Trypanosoma brucei
    • Redmond S, Vadivelu J, Field MC (2003) RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei. Mol Biochem Parasitol 128: 115-118.
    • (2003) Mol Biochem Parasitol , vol.128 , pp. 115-118
    • Redmond, S.1    Vadivelu, J.2    Field, M.C.3
  • 70
    • 33747371179 scopus 로고    scopus 로고
    • Characterization and developmentally regulated localization of the mitochon- drial carrier protein homologue MCP6 from Trypanosoma brucei
    • Colasante C, Alibu VP, Kirchberger S, Tjaden J, Clayton C, et al. (2006) Characterization and developmentally regulated localization of the mitochon- drial carrier protein homologue MCP6 from Trypanosoma brucei. Eukaryot Cell 5: 1194-1205.
    • (2006) Eukaryot Cell , vol.5 , pp. 1194-1205
    • Colasante, C.1    Alibu, V.P.2    Kirchberger, S.3    Tjaden, J.4    Clayton, C.5
  • 71
    • 62449110058 scopus 로고    scopus 로고
    • Functional characterisation of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes in Trypanosoma brucei
    • Bessat M, Ersfeld K (2009) Functional characterisation of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes in Trypanosoma brucei. Mol Microbiol.
    • (2009) Mol Microbiol
    • Bessat, M.1    Ersfeld, K.2
  • 72
    • 66849128079 scopus 로고    scopus 로고
    • Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography
    • Lacomble S, Vaughan S, Gadelha C, Morphew MK, Shaw MK, et al. (2009) Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography. J Cell Sci 122: 1081-1090.
    • (2009) J Cell Sci , vol.122 , pp. 1081-1090
    • Lacomble, S.1    Vaughan, S.2    Gadelha, C.3    Morphew, M.K.4    Shaw, M.K.5
  • 73
    • 0030978125 scopus 로고    scopus 로고
    • Partitioning of large and minichromosomes in Trypanosoma brucei
    • Ersfeld K, Gull K (1997) Partitioning of large and minichromosomes in Trypanosoma brucei. Science 276: 611-614.
    • (1997) Science , vol.276 , pp. 611-614
    • Ersfeld, K.1    Gull, K.2
  • 74
    • 0035234284 scopus 로고    scopus 로고
    • Preparation of recombinant kinesin superfamily proteins using the baculovirus system
    • Vernos I, ed, Totowa: Humana Press
    • Hirokawa N, Noda Y (2001) Preparation of recombinant kinesin superfamily proteins using the baculovirus system. In: Vernos I, ed. Kinesin Protocols. Totowa: Humana Press. pp 57-63.
    • (2001) Kinesin Protocols , pp. 57-63
    • Hirokawa, N.1    Noda, Y.2
  • 75
    • 0035229287 scopus 로고    scopus 로고
    • Assays for microtubule-destabilizing kinesins
    • Desai A, Walczak CE (2001) Assays for microtubule-destabilizing kinesins. Methods Mol Biol 164: 109-121.
    • (2001) Methods Mol Biol , vol.164 , pp. 109-121
    • Desai, A.1    Walczak, C.E.2
  • 76
    • 0028363764 scopus 로고
    • Drosophila kinesin minimal motor domain expressed in Escherichia coli. Purification and kinetic characterization
    • Huang TG, Hackney DD (1994) Drosophila kinesin minimal motor domain expressed in Escherichia coli. Purification and kinetic characterization. J Biol Chem 269: 16493-16501.
    • (1994) J Biol Chem , vol.269 , pp. 16493-16501
    • Huang, T.G.1    Hackney, D.D.2
  • 77
    • 0017168578 scopus 로고
    • Trypanosoma brucei: A rapid "matching" method for estimating the host's parasitemia
    • Herbert WJ, Lumsden WH (1976) Trypanosoma brucei: a rapid "matching" method for estimating the host's parasitemia. Exp Parasitol 40: 427-431.
    • (1976) Exp Parasitol , vol.40 , pp. 427-431
    • Herbert, W.J.1    Lumsden, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.