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Volumn 8, Issue 9, 2006, Pages 913-923

Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DIMER; KINESIN; KINESIN 8; KIP3 PROTEIN; MICROTUBULE PROTEIN; MOLECULAR MOTOR; TUBULIN; UNCLASSIFIED DRUG;

EID: 33748158378     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1457     Document Type: Article
Times cited : (273)

References (50)
  • 1
    • 0033791649 scopus 로고    scopus 로고
    • Structural insights into microtubule function
    • Nogales, E. Structural insights into microtubule function. Annu. Rev. Biochem. 69, 277-302 (2000).
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 277-302
    • Nogales, E.1
  • 2
    • 0034677872 scopus 로고    scopus 로고
    • Roles of motor proteins in building microtubule-based structures: A basic principle of cellular design
    • Sharp, D. J., Rogers, G. C. & Scholey, J. M. Roles of motor proteins in building microtubule-based structures: A basic principle of cellular design. Biochim. Biophys. Acta 1496, 128-141 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1496 , pp. 128-141
    • Sharp, D.J.1    Rogers, G.C.2    Scholey, J.M.3
  • 3
    • 2942557233 scopus 로고    scopus 로고
    • Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules
    • Busch, K. E., Hayles, J., Nurse, P. & Brunner, D. Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules. Dev. Cell 6, 831-843 (2004).
    • (2004) Dev. Cell , vol.6 , pp. 831-843
    • Busch, K.E.1    Hayles, J.2    Nurse, P.3    Brunner, D.4
  • 4
    • 2942617092 scopus 로고    scopus 로고
    • Cell cycle control of kinesinmediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation
    • Carvalho, P., Gupta, M. L., Jr., Hoyt, M. A. & Pellman, D. Cell cycle control of kinesinmediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev. Cell 6, 815-829 (2004).
    • (2004) Dev. Cell , vol.6 , pp. 815-829
    • Carvalho, P.1    Gupta Jr., M.L.2    Hoyt, M.A.3    Pellman, D.4
  • 5
    • 4644219804 scopus 로고    scopus 로고
    • The mechanism, function and regulation of depolymerizing kinesins during mitosis
    • Moore, A. & Wordeman, L. The mechanism, function and regulation of depolymerizing kinesins during mitosis. Trends Cell Biol. 14, 537-546 (2004).
    • (2004) Trends Cell Biol. , vol.14 , pp. 537-546
    • Moore, A.1    Wordeman, L.2
  • 6
    • 0028245510 scopus 로고
    • Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends
    • Endow, S. A. et al. Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. EMBO J. 13, 2708-2713 (1994).
    • (1994) EMBO J. , vol.13 , pp. 2708-2713
    • Endow, S.A.1
  • 7
    • 23244462047 scopus 로고    scopus 로고
    • Cik1 targets the minus-end kinesin depolymerase kar3 to microtubule plus ends
    • Sproul, L. R., Anderson, D. J., Mackey, A. T., Saunders, W. S. & Gilbert, S. P. Cik1 targets the minus-end kinesin depolymerase kar3 to microtubule plus ends. Curr. Biol. 15, 1420-1427 (2005).
    • (2005) Curr. Biol. , vol.15 , pp. 1420-1427
    • Sproul, L.R.1    Anderson, D.J.2    Mackey, A.T.3    Saunders, W.S.4    Gilbert, S.P.5
  • 8
    • 0030931849 scopus 로고    scopus 로고
    • Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins
    • Cottingham, F. R. & Hoyt, M. A. Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J. Cell. Biol. 138, 1041-1053 (1997).
    • (1997) J. Cell. Biol. , vol.138 , pp. 1041-1053
    • Cottingham, F.R.1    Hoyt, M.A.2
  • 9
    • 0030928162 scopus 로고    scopus 로고
    • Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration
    • DeZwaan, T. M., Ellingson, E., Pellman, D. & Roof, D. M. Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration. J. Cell. Biol. 138, 1023-1040 (1997).
    • (1997) J. Cell. Biol. , vol.138 , pp. 1023-1040
    • DeZwaan, T.M.1    Ellingson, E.2    Pellman, D.3    Roof, D.M.4
  • 10
    • 0031878092 scopus 로고    scopus 로고
    • The kinesin-related proteins, Kip2p and Kip3p, function differently in nuclear migration in yeast
    • Miller, R. K. et al. The kinesin-related proteins, Kip2p and Kip3p, function differently in nuclear migration in yeast. Mol. Biol. Cell 9, 2051-2068 (1998).
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2051-2068
    • Miller, R.K.1
  • 11
    • 0035661591 scopus 로고    scopus 로고
    • Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast
    • West, R. R., Malmstrom, T., Troxell, C. L. & McIntosh, J. R. Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast. Mol. Biol. Cell 12, 3919-3932 (2001).
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3919-3932
    • West, R.R.1    Malmstrom, T.2    Troxell, C.L.3    McIntosh, J.R.4
  • 12
    • 0037117406 scopus 로고    scopus 로고
    • Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A
    • Garcia, M. A., Koonrugsa, N. & Toda, T. Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A. Curr. Biol. 12, 610-621 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 610-621
    • Garcia, M.A.1    Koonrugsa, N.2    Toda, T.3
  • 13
    • 21644484234 scopus 로고    scopus 로고
    • Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle
    • Gatt, M. K. et al. Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle. J. Cell Sci. 118, 2671-2682 (2005).
    • (2005) J. Cell Sci. , vol.118 , pp. 2671-2682
    • Gatt, M.K.1
  • 14
    • 0141768258 scopus 로고    scopus 로고
    • The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line
    • Goshima, G. & Vale, R. D. The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line. J. Cell Biol. 162, 1003-1016 (2003).
    • (2003) J. Cell Biol. , vol.162 , pp. 1003-1016
    • Goshima, G.1    Vale, R.D.2
  • 16
    • 0031000089 scopus 로고    scopus 로고
    • Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila
    • Pereira, A. J., Dalby, B., Stewart, R. J., Doxsey, S. J. & Goldstein, L. S. Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. J. Cell Biol. 136, 1081-1090 (1997).
    • (1997) J. Cell Biol. , vol.136 , pp. 1081-1090
    • Pereira, A.J.1    Dalby, B.2    Stewart, R.J.3    Doxsey, S.J.4    Goldstein, L.S.5
  • 17
    • 2942690106 scopus 로고    scopus 로고
    • The Kip3-like kinesin KipB moves along microtubules and determines spindle position during synchronized mitoses in Aspergillus nidulans hyphae
    • Rischitor, P. E., Konzack, S. & Fischer, R. The Kip3-like kinesin KipB moves along microtubules and determines spindle position during synchronized mitoses in Aspergillus nidulans hyphae. Eukaryot. Cell 3, 632-645 (2004).
    • (2004) Eukaryot. Cell , vol.3 , pp. 632-645
    • Rischitor, P.E.1    Konzack, S.2    Fischer, R.3
  • 18
    • 33644894727 scopus 로고    scopus 로고
    • Analysis of kinesin motor function at budding yeast kinetochores
    • Tytell, J. D. & Sorger, P. K. Analysis of kinesin motor function at budding yeast kinetochores. J. Cell Biol. 172, 861-874 (2006).
    • (2006) J. Cell Biol. , vol.172 , pp. 861-874
    • Tytell, J.D.1    Sorger, P.K.2
  • 19
    • 21844473254 scopus 로고    scopus 로고
    • Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference
    • Zhu, C. et al. Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol. Biol. Cell 16, 3187-3199 (2005).
    • (2005) Mol. Biol. Cell , vol.16 , pp. 3187-3199
    • Zhu, C.1
  • 20
    • 24344465919 scopus 로고    scopus 로고
    • Analysis of the kinesin superfamily: Insights into structure and function
    • Miki, H., Okada, Y. & Hirokawa, N. Analysis of the kinesin superfamily: insights into structure and function. Trends Cell Biol. 15, 467-476 (2005).
    • (2005) Trends Cell Biol. , vol.15 , pp. 467-476
    • Miki, H.1    Okada, Y.2    Hirokawa, N.3
  • 21
    • 0035897419 scopus 로고    scopus 로고
    • Stu2 promotes mitotic spindle elongation in anaphase
    • Severin, F., Habermann, B., Huffaker, T. & Hyman, T. Stu2 promotes mitotic spindle elongation in anaphase. J. Cell Biol. 153, 435-442 (2001).
    • (2001) J. Cell Biol. , vol.153 , pp. 435-442
    • Severin, F.1    Habermann, B.2    Huffaker, T.3    Hyman, T.4
  • 22
    • 1342296567 scopus 로고    scopus 로고
    • A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops
    • Ogawa, T., Nitta, R., Okada, Y. & Hirokawa, N. A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell 116, 591-602 (2004).
    • (2004) Cell , vol.116 , pp. 591-602
    • Ogawa, T.1    Nitta, R.2    Okada, Y.3    Hirokawa, N.4
  • 23
    • 2342565893 scopus 로고    scopus 로고
    • Structure of a kinesin microtubule depolymerization machine
    • Shipley, K. et al. Structure of a kinesin microtubule depolymerization machine. EMBO J. 23, 1422-1432 (2004).
    • (2004) EMBO J. , vol.23 , pp. 1422-1432
    • Shipley, K.1
  • 24
    • 0032749860 scopus 로고    scopus 로고
    • Novel roles for Saccharomyces cerevisiae mitotic spindle motors
    • Cottingham, F. R., Gheber, L., Miller, D. L. & Hoyt, M. A. Novel roles for Saccharomyces cerevisiae mitotic spindle motors. J. Cell Biol. 147, 335-350 (1999).
    • (1999) J. Cell Biol. , vol.147 , pp. 335-350
    • Cottingham, F.R.1    Gheber, L.2    Miller, D.L.3    Hoyt, M.A.4
  • 25
    • 0032476715 scopus 로고    scopus 로고
    • Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast
    • Straight, A. F., Sedat, J. W. & Murray, A. W. Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast. J. Cell Biol. 143, 687-694 (1998).
    • (1998) J. Cell Biol. , vol.143 , pp. 687-694
    • Straight, A.F.1    Sedat, J.W.2    Murray, A.W.3
  • 26
    • 0032488046 scopus 로고    scopus 로고
    • Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells
    • Waterman-Storer, C. M., Desai, A., Bulinski, J. C. & Salmon, E. D. Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells. Curr. Biol. 8, 1227-1230 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 1227-1230
    • Waterman-Storer, C.M.1    Desai, A.2    Bulinski, J.C.3    Salmon, E.D.4
  • 27
    • 12344320203 scopus 로고    scopus 로고
    • Microtubule plus-end-tracking proteins: Mechanisms and functions
    • Akhmanova, A. & Hoogenraad, C. C. Microtubule plus-end-tracking proteins: Mechanisms and functions. Curr. Opin. Cell Biol. 17, 47-54 (2005).
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 47-54
    • Akhmanova, A.1    Hoogenraad, C.C.2
  • 28
    • 0027728131 scopus 로고
    • Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy
    • Howard, J. & Hyman, A. A. Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. Methods Cell Biol. 39, 105-113 (1993).
    • (1993) Methods Cell Biol. , vol.39 , pp. 105-113
    • Howard, J.1    Hyman, A.A.2
  • 29
    • 0027075124 scopus 로고
    • Role of GTP hydrolysis in microtubule dynamics: Information from a slowly hydrolyzable analogue, GMPCPP
    • Hyman, A. A., Salser, S., Drechsel, D. N., Unwin, N. & Mitchison, T. J. Role of GTP hydrolysis in microtubule dynamics: Information from a slowly hydrolyzable analogue, GMPCPP. Mol. Biol. Cell 3, 1155-1167 (1992).
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1155-1167
    • Hyman, A.A.1    Salser, S.2    Drechsel, D.N.3    Unwin, N.4    Mitchison, T.J.5
  • 30
    • 0033534575 scopus 로고    scopus 로고
    • Kin I kinesins are microtubule-destabilizing enzymes
    • Desai, A., Verma, S., Mitchison, T. J. & Walczak, C. E. Kin I kinesins are microtubule-destabilizing enzymes. Cell 96, 69-78 (1999).
    • (1999) Cell , vol.96 , pp. 69-78
    • Desai, A.1    Verma, S.2    Mitchison, T.J.3    Walczak, C.E.4
  • 31
    • 0037292454 scopus 로고    scopus 로고
    • The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends
    • Hunter, A. W. et al. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol. Cell 11, 445-457 (2003).
    • (2003) Mol. Cell , vol.11 , pp. 445-457
    • Hunter, A.W.1
  • 32
    • 0037459058 scopus 로고    scopus 로고
    • Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignment
    • Liakopoulos, D., Kusch, J., Grava, S., Vogel, J. & Barral, Y. Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignment. Cell 112, 561-574 (2003).
    • (2003) Cell , vol.112 , pp. 561-574
    • Liakopoulos, D.1    Kusch, J.2    Grava, S.3    Vogel, J.4    Barral, Y.5
  • 33
    • 2942557125 scopus 로고    scopus 로고
    • Dynamic microtubules lead the way for spindle positioning
    • Pearson, C. G. & Bloom, K. Dynamic microtubules lead the way for spindle positioning. Nature Rev. Mol. Cell Biol. 5, 481-492 (2004).
    • (2004) Nature Rev. Mol. Cell Biol. , vol.5 , pp. 481-492
    • Pearson, C.G.1    Bloom, K.2
  • 34
    • 0034657914 scopus 로고    scopus 로고
    • Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae
    • Adames, N. R. & Cooper, J. A. Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae. J. Cell Biol. 149, 863-874 (2000).
    • (2000) J. Cell Biol. , vol.149 , pp. 863-874
    • Adames, N.R.1    Cooper, J.A.2
  • 35
    • 0042426023 scopus 로고    scopus 로고
    • The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast
    • Maddox, P. S., Stemple, J. K., Satterwhite, L., Salmon, E. D. & Bloom, K. The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast. Curr. Biol. 13, 1423-1428 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 1423-1428
    • Maddox, P.S.1    Stemple, J.K.2    Satterwhite, L.3    Salmon, E.D.4    Bloom, K.5
  • 36
    • 0034266786 scopus 로고    scopus 로고
    • CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast
    • Brunner, D. & Nurse, P. CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell 102, 695-704 (2000).
    • (2000) Cell , vol.102 , pp. 695-704
    • Brunner, D.1    Nurse, P.2
  • 37
    • 0035897404 scopus 로고    scopus 로고
    • A mechanism for nuclear positioning in fission yeast based on microtubule pushing
    • Tran, P. T., Marsh, L., Doye, V., Inoue, S. & Chang, F. A mechanism for nuclear positioning in fission yeast based on microtubule pushing. J. Cell Biol. 153, 397-411 (2001).
    • (2001) J. Cell Biol. , vol.153 , pp. 397-411
    • Tran, P.T.1    Marsh, L.2    Doye, V.3    Inoue, S.4    Chang, F.5
  • 38
    • 0036711845 scopus 로고    scopus 로고
    • Life cycle of MTs: Persistent growth in the cell interior, asymmetric transition frequencies and effects of the cell boundary
    • Komarova, Y. A., Vorobjev, I. A. & Borisy, G. G. Life cycle of MTs: persistent growth in the cell interior, asymmetric transition frequencies and effects of the cell boundary. J. Cell Sci. 115, 3527-3539 (2002).
    • (2002) J. Cell Sci. , vol.115 , pp. 3527-3539
    • Komarova, Y.A.1    Vorobjev, I.A.2    Borisy, G.G.3
  • 39
    • 1542317579 scopus 로고    scopus 로고
    • A kinesin-like motor inhibits microtubule dynamic instability
    • Bringmann, H. et al. A kinesin-like motor inhibits microtubule dynamic instability. Science 303, 1519-1522 (2004).
    • (2004) Science , vol.303 , pp. 1519-1522
    • Bringmann, H.1
  • 40
    • 14744287039 scopus 로고    scopus 로고
    • Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase
    • Mennella, V. et al. Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nature Cell Biol. 7, 235-245 (2005).
    • (2005) Nature Cell Biol. , vol.7 , pp. 235-245
    • Mennella, V.1
  • 41
    • 18844410038 scopus 로고    scopus 로고
    • MCAK associates with the tips of polymerizing microtubules
    • Moore, A. T. et al. MCAK associates with the tips of polymerizing microtubules. J. Cell Biol. 169, 391-397 (2005).
    • (2005) J. Cell Biol. , vol.169 , pp. 391-397
    • Moore, A.T.1
  • 42
    • 0033045090 scopus 로고    scopus 로고
    • Regional regulation of microtubule dynamics in polarized, motile cells
    • Wadsworth, P. Regional regulation of microtubule dynamics in polarized, motile cells. Cell Motil. Cytoskeleton 42, 48-59 (1999).
    • (1999) Cell Motil. Cytoskeleton , vol.42 , pp. 48-59
    • Wadsworth, P.1
  • 43
    • 0038457895 scopus 로고    scopus 로고
    • Regulation of leading edge microtubule and actin dynamics downstream of Rac1
    • Wittmann, T., Bokoch, G. M. & Waterman-Storer, C. M. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J. Cell Biol. 161, 845-851 (2003).
    • (2003) J. Cell Biol. , vol.161 , pp. 845-851
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 44
    • 0037799920 scopus 로고    scopus 로고
    • PAR proteins regulate microtubule dynamics at the cell cortex in C. elegans
    • Labbe, J. C., Maddox, P. S., Salmon, E. D. & Goldstein, B. PAR proteins regulate microtubule dynamics at the cell cortex in C. elegans. Curr. Biol. 13, 707-714 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 707-714
    • Labbe, J.C.1    Maddox, P.S.2    Salmon, E.D.3    Goldstein, B.4
  • 45
    • 0036678201 scopus 로고    scopus 로고
    • The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells
    • Kline-Smith, S. L. & Walczak, C. E. The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells. Mol. Biol. Cell 13, 2718-2731 (2002).
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2718-2731
    • Kline-Smith, S.L.1    Walczak, C.E.2
  • 47
    • 0025762199 scopus 로고
    • Preparation of modified tubulins
    • Hyman, A. et al. Preparation of modified tubulins. Methods Enzymol. 196, 478-485 (1991).
    • (1991) Methods Enzymol. , vol.196 , pp. 478-485
    • Hyman, A.1
  • 48
    • 0027720243 scopus 로고
    • Microtubule and axoneme gliding assays for force production by microtubule motor proteins
    • Paschal, B. M. & Vallee, R. B. Microtubule and axoneme gliding assays for force production by microtubule motor proteins. Methods Cell Biol. 39, 65-74 (1993).
    • (1993) Methods Cell Biol. , vol.39 , pp. 65-74
    • Paschal, B.M.1    Vallee, R.B.2
  • 49
    • 0028363764 scopus 로고
    • Drosophila kinesin minimal motor domain expressed in Escherichia coli. Purification and kinetic characterization
    • Huang, T. G. & Hackney, D. D. Drosophila kinesin minimal motor domain expressed in Escherichia coli. Purification and kinetic characterization. J. Biol. Chem. 269, 16493-16501 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 16493-16501
    • Huang, T.G.1    Hackney, D.D.2


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