HNE-induced 5-LO expression is regulated by NF-κB/ERK and Sp1/p38 MAPK pathways via EGF receptor in murine macrophages

Cardiovascular Research

Volumn 88, Issue 2, 2010, Pages 352-359

  Lee, Seung J ^a   Kim, Chae E ^a   Seo, Kyo W ^a   Kim, Chi D ^a  

^a Pusan National University   (South Korea)

Author keywords

5 LO; Atherosclerosis; HNE; Macrophages

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 HYDROXYNONENAL; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; ARACHIDONATE 5 LIPOXYGENASE; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE DELETION; GENE SEQUENCE; GENE SILENCING; GENETIC TRANSCRIPTION; GENOMICS; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION SITE; UPREGULATION;

ALDEHYDES; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; BASE SEQUENCE; BINDING SITES; CELL LINE; ENZYME INDUCTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENES, REPORTER; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 77958081965     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq194     Document Type: Article

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