Chromosomal instability and telomere lengths of each chromosomal arm measured by Q-FISH in human fibroblast strains prior to replicative senescence

Mechanisms of Ageing and Development

Volumn 131, Issue 10, 2010, Pages 614-624

  Takubo, Kaiyo ^a   Aida, Junko ^a   Izumiyama, Naotaka ^a   Ishikawa, Naoshi ^a   Fujiwara, Mutsunori ^b   Poon, Steven S S ^c   Kondo, Hiroshi ^d   Kammori, Makoto ^e   Matsuura, Masaaki ^f   Sawabe, Motoji ^g   Arai, Tomio ^g   Baird, Duncan M ^h   Nakamura, Ken Ichi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b JAPANESE RED CROSS MEDICAL CENTER   (Japan)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

^d UNIVERSITY OF HUMAN ARTS AND SCIENCES   (Japan)

^e TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^f CANCER INSTITUTE   (Japan)

^g Tokyo Metropolitan Institute of Gerontology   (Japan)

^h CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Anaphase bridge; Cellular senescence; Chromosomal instability; Q FISH; Telomere

Indexed keywords

ADULT; AGED; ANAPHASE; ARTICLE; CELL AGING; CELL STRAIN; CHROMOSOMAL INSTABILITY; CHROMOSOME 21Q; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME ARM; CHROMOSOME BANDING PATTERN; CHROMOSOME G BAND; CHROMOSOME LOSS; CHROMOSOME Q BAND; CHROMOSOME XQ; CONTROLLED STUDY; DIPLOIDY; FEMALE; FETUS; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; IMAGE ANALYSIS; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEX CHROMOSOME; SOUTHERN BLOTTING; TELOMERE; TELOPHASE; TETRAPLOIDY; X CHROMOSOME;

ADULT; AGED; ANAPHASE; CELL AGING; CELL LINE; CHROMOSOMAL INSTABILITY; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, X; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; TELOMERE;

EID: 77957927382     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2010.08.007     Document Type: Article

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