Paeonol exerts anti-angiogenic and anti-metastatic activities through downmodulation of Akt activation and inactivation of matrix metalloproteinases

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 7, 2009, Pages 1142-1147

  Kim, Seung Ae ^a   Lee, Hyo Jeong ^a   Ahn, Kwang Seok ^a   Lee, Hyo Jung ^a   Lee, Eun Ok ^a   Ahn, Kyoo Seok ^a   Choi, Seung Hoon ^a   Jung, Soo Jin ^a   Kim, Ji Young ^a   Baek, Namin ^a   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Akt; Angiogenesis; Basic fibroblast growth factor; Human umbilical vein endothelial cell; Paeonol

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BASIC FIBROBLAST GROWTH FACTOR; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; PEONOL; PROTEIN KINASE B; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CHICKEN; CHORIOALLANTOIS; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENTIATION; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FIBROSARCOMA; HUMAN; HUMAN CELL; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ACETOPHENONES; ANGIOGENESIS INHIBITORS; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MOVEMENT; CELL PROLIFERATION; CHICK EMBRYO; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 67650716768     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1142     Document Type: Article

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