An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis

Carcinogenesis

Volumn 27, Issue 12, 2006, Pages 2455-2463

  Lee, Hyo Jeong ^a,b   Lee, Eun Ok ^a   Rhee, Yun Hee ^a   Ahn, Kyoo Seok ^b   Li, Guang Xun ^b   Jiang, Cheng ^b   Lü, Junxuan ^b   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGELICA GIGAS EXTRACT; ANTINEOPLASTIC AGENT; ASINI GELATINUM EXTRACT; ASTRAGALUS MEMBRANACEUS EXTRACT; BASIC FIBROBLAST GROWTH FACTOR; BENINCASA HISPIDA EXTRACT; BLETILLA STRIATA EXTRACT; GINSENG EXTRACT; HERBACEOUS AGENT; HYPOXIA INDUCIBLE FACTOR 1; KA MI KAE KYUK TANG; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PATRINIA VILLOSA EXTRACT; PHASEOLUS ANGULARIS EXTRACT; PLANT EXTRACT; TULIPA EDULIS EXTRACT; VASCULOTROPIN; ZANTHOXYLUM PIPERITUM EXTRACT;

ANGELICA; ANGELICA GIGAS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASINI GELATINUM; BEAN; BENINCASA HISPIDA; BLETILLA STRIATA; CARCINOGENESIS; COLON CANCER; CONTROLLED STUDY; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG TARGETING; ENZYME PHOSPHORYLATION; FEMALE; HERB; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEWIS CARCINOMA; LIVER METASTASIS; MOUSE; NICK END LABELING; NONHUMAN; PATRINIA; PATRINIA VILLOSA; PHASEOLUS ANGULARIS; PLANT ROOT; PLANT SEED; PLANT STEM; PLANT TUBER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; TULIP; TULIPA EDULIS; TUMOR XENOGRAFT; VASCULAR ENDOTHELIUM; WEIGHT REDUCTION; ZANTHOXYLUM; ZANTHOXYLUM PIPERITUM;

ALLANTOIS; ANIMALS; APOPTOSIS; CELL DIVISION; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; CHICK EMBRYO; CHORION; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HUMANS; KOREA; LIVER NEOPLASMS; MEDICINE, ORIENTAL TRADITIONAL; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PLANT EXTRACTS; UMBILICAL VEINS;

EID: 33845366687     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl104     Document Type: Article

References (27)

1. Jemal,A., Murray,T., Ward,E., Samuels,A., Tiwari,R.C., Ghafoor,A., Feuer,E.J. and Thun,M.J. (2005) Cancer statistics, 2005. CA Cancer J. Clin., 55, 10-30.
2. Petrylak,D.P. (2005) The current role of chemotherapy in metastatic hormone-refractory prostate cancer. Urology, 65 (Suppl. 5), 3-7, discussion 7-8.
3. Evans,T. (2005) Chemotherapy in advanced non-small cell lung cancer. Semin. Respir. Crit. Care Med., 26, 304-313.
4. Buchanan,D.R., White,J.D., O'Mara,A.M., Kelaghan,J.W., Smith,W.B. and Minasian,L.M. (2005) Research-design issues in cancer-symptom-management trials using complementary and alternative medicine: Lessons from the National Cancer Institute Community Clinical Oncology Program experience. J. Clin. Oncol., 23, 6682-6689.
5. Jiang,C., Lee,H.J., Li,G.X. et al. (2006) Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: Identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. Cancer Res., 66, 453-463.
6. Folkman,J. (1971) Tumor angiogenesis: Therapeutic implications. N. Engl. J. Med., 285, 1182-1186.
7. Folkman,J. and Shing,Y. (1992) Angiogenesis. J. Biol. Chem., 267, 10931-10934.
8. Folkman,J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med., 1, 27-31.
9. Folkman,J. (2003) Angiogenesis and apoptosis. Semin. Cancer Biol., 13, 159-167.
10. Hanahan,D. and Folkman,J. (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86, 353-364.
11. Carmeliet,P. and Jain,R.K. (2000) Angiogenesis in cancer and other diseases. Nature, 407, 249-257.
12. Bergers,G. and Benjamin,L.E. (2003) Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer, 3, 401-410.
13. Chen,C.H., Poucher,S.M., Lu,J. and Henry,P.D. (2004) Fibroblast growth factor 2: From laboratory evidence to clinical application. Curr. Vasc. Pharmacol., 2, 33-43.
14. Madhusudan,S. and Harris,A.L. (2002) Drug inhibition of angiogenesis. Curr. Opin. Pharmacol., 2, 403-414.
15. Tosetti,F., Ferrari,N., De Flora,S. and Albini,A. (2002) Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents. FASEB. J., 16, 2-14.
16. Jaffe,E.A., Nachman,R.L., Becker,C.G. and Minick,C.R. (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest., 52, 2745-2756.
17. Huh,J.E., Lee,E.O., Kim,M.S., Kang,K.S., Kim,C.H., Cha,B.C., Surh,Y.J. and Kim,S.H. (2005) Penta-O-galloyl-beta-D-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways. Carcinogenesis, 26, 1436-1445.
18. Ohnishi,Y., Sakamoto,T., Fujii,H. et al. (1997) Characterization of a liver metastatic variant of murine colon 26 carcinoma cells. Tumour Biol., 18, 113-122.
19. Grant,D.S., Kinsella,J.L., Fridman,R., Auerbach,R., Piasecki,B.A., Yamada,Y., Zain,M. and Kleinman,H.K. (1992) Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo. J. Cell. Physiol., 153, 614-625.
20. Passaniti,A., Taylor,R.M., Pili,R., Guo,Y., Long,P.V., Haney,J.A., Pauly,R.R., Grant,D.S. and Martin,G.R. (1992) A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Lab. Invest., 67, 519-528.
21. Kibbey,M.C., Grant,D.S. and Kleinman,H.K. (1992) Role of the SIKVAV site of laminin in promotion of angiogenesis and tumor growth: An in vivo Matrigel model. J. Natl Cancer Inst., 84, 1633-1638.
22. Lee,S.J., Sakurai,H., Koizumi,K., Song,G.Y., Bae,Y.S., Kim,H.M., Kang,K.S., Surh,Y.J., Saiki,I. and Kim,S.H. (2006) MAPK regulation and caspase activation are required in DMNQ S-52 induced apoptosis in Lewis lung carcinoma cells. Cancer Lett., 233, 57-67.
23. Lee,S.J., Sakurai,H., Oshima,K., Kim,S.H. and Saiki,I. (2003) Anti-metastatic and anti-angiogenic activities of a new matrix metalloproteinase inhibitor, TN-6b. Eur. J. Cancer, 39, 1632-1641.
24. Semenza,G.L., Agani,F., Iyer,N., Kotch,L., Laughner,E., Leung,S. and Yu,A. (1999) Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1. Ann. NY Acad. Sci., 874, 262-268.
25. Liu,L. and Simon,M.C. (2004) Regulation of transcription and translation by hypoxia. Cancer Biol. Ther., 3, 492-497.
26. Bjorklund,M. and Koivunen,E. (2005) Gelatinase-mediated migration and invasion of cancer cells. Biochim. Biophys. Acta., 1755, 37-69.
27. Li,C.Y., Shan,S., Cao,Y. and Dewhirst,M.W. (2000) Role of incipient angiogenesis in cancer metastasis. Cancer Metastasis. Rev., 19, 7-11.