메뉴 건너뛰기




Volumn 5, Issue 8, 2010, Pages

Thymic alterations in GM2 gangliosidoses model mice

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BETA N ACETYLHEXOSAMINIDASE; CD19 ANTIGEN; CD3 ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD79A ANTIGEN; CD79B ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CXCR5; COLONY STIMULATING FACTOR 2 RECEPTOR 1; COLONY STIMULATING FACTOR RECEPTOR; COMPLEMENTARY DNA; CXCL13 CHEMOKINE; EARLY B CELL FACTOR 1; FC RECEPTOR; GANGLIOSIDE GM2; GENE PRODUCT; GLYCOLIPID; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR ALPHA; INTERLEUKIN 10 RECEPTOR BETA; INTERLEUKIN 13 RECEPTOR ALPHA1; MACROPHAGE EXPRESSED PROTEIN 1; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE TO MACROPHAGE DIFFERENTIATION ASSOCIATED PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; BETA N ACETYLHEXOSAMINIDASE BETA CHAIN; MESSENGER RNA;

EID: 77957816698     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012105     Document Type: Article
Times cited : (11)

References (47)
  • 1
    • 0025826050 scopus 로고
    • Lysosomal storage diseases
    • Neufeld EF (1991) Lysosomal storage diseases. Annu Rev Biochem 60: 257-280.
    • (1991) Annu Rev Biochem , vol.60 , pp. 257-280
    • Neufeld, E.F.1
  • 3
    • 0028292563 scopus 로고
    • Structure and expression of the mouse β-hexosaminidase genes, Hexa and Hexb
    • Yamanaka S, Johnson ON, Norflus F, Boles DJ, Proia RL (1994) Structure and expression of the mouse β-hexosaminidase genes, Hexa and Hexb. Genomics 1994 21: 588-596.
    • (1994) Genomics , Issue.21 , pp. 588-596
    • Yamanaka, S.1    Johnson, O.N.2    Norflus, F.3    Boles, D.J.4    Proia, R.L.5
  • 4
    • 0029113867 scopus 로고
    • Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Mice lacking both subunits of lysosomal β-hexosaminidase display gangliosidosis and mucopolysaccharidosis
    • Sango K, Yamanaka S, Hoffmann A, Okuda Y, Grinberg A, et al. (1995) Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Mice lacking both subunits of lysosomal β-hexosaminidase display gangliosidosis and mucopolysaccharidosis. Nat Genet 11: 170-176.
    • (1995) Nat Genet , vol.11 , pp. 170-176
    • Sango, K.1    Yamanaka, S.2    Hoffmann, A.3    Okuda, Y.4    Grinberg, A.5
  • 5
    • 9044236158 scopus 로고    scopus 로고
    • Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases
    • Phaneuf D, Wakamatsu N, Huang J-Q, Borowski A, Peterson AC, et al. (1996) Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases. Hum Mol Genet 5: 1-14.
    • (1996) Hum Mol Genet , vol.5 , pp. 1-14
    • Phaneuf, D.1    Wakamatsu, N.2    Huang, J.-Q.3    Borowski, A.4    Peterson, A.C.5
  • 6
    • 0030782030 scopus 로고    scopus 로고
    • M2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases
    • Huang JQ, Trasler JM, Igdoura S, Michaud J, Hanal N, et al. (1997) Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases. Hum Mol Genet 6: 1879-1885.
    • (1997) Hum Mol Genet , vol.6 , pp. 1879-1885
    • Huang, J.Q.1    Trasler, J.M.2    Igdoura, S.3    Michaud, J.4    Hanal, N.5
  • 7
    • 0032080858 scopus 로고    scopus 로고
    • Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice
    • Norflus F, Tifft CJ, McDonald MP, Goldstein G, Crawley JN, et al. (1999) Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice. J Clin Invest 101: 1881-1888.
    • (1999) J Clin Invest , vol.101 , pp. 1881-1888
    • Norflus, F.1    Tifft, C.J.2    McDonald, M.P.3    Goldstein, G.4    Crawley, J.N.5
  • 8
    • 0034718598 scopus 로고    scopus 로고
    • Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation
    • Wada R, Tifft CJ, Proia RL (2000) Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation. Proc Natl Acad Sci USA 97: 10954-10959.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10954-10959
    • Wada, R.1    Tifft, C.J.2    Proia, R.L.3
  • 10
    • 1342268315 scopus 로고    scopus 로고
    • Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses
    • Yamaguchi A, Katsuyama K, Nagahama K, Takai T, Aoki I, et al. (2004) Possible role of autoantibodies in the pathophysiology of GM2 gangliosidoses. J Clin Invest 113: 200-208.
    • (2004) J Clin Invest , vol.113 , pp. 200-208
    • Yamaguchi, A.1    Katsuyama, K.2    Nagahama, K.3    Takai, T.4    Aoki, I.5
  • 11
    • 63849276774 scopus 로고    scopus 로고
    • Innate and adaptive immune activation in the brain of MPS IIIB mouse model
    • DiRosario J, Divers E, Wang C, Etter J, Charrier A, et al. (2008) Innate and adaptive immune activation in the brain of MPS IIIB mouse model. J Neurosci Res 87: 978-990.
    • (2008) J Neurosci Res , vol.87 , pp. 978-990
    • Dirosario, J.1    Divers, E.2    Wang, C.3    Etter, J.4    Charrier, A.5
  • 12
    • 71749101489 scopus 로고    scopus 로고
    • An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease
    • Chattopadhyay S, Ito M, Cooper JD, Brooks AI, Curran TM, et al. (2002) An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease. Hum Mol Genet 11: 1421-1431.
    • (2002) Hum Mol Genet , vol.11 , pp. 1421-1431
    • Chattopadhyay, S.1    Ito, M.2    Cooper, J.D.3    Brooks, A.I.4    Curran, T.M.5
  • 13
  • 15
    • 10444225954 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase autoimmunity in Batten disease and other disorders
    • Pearce DA, Atkinson M, Tagle DA (2004) Glutamic acid decarboxylase autoimmunity in Batten disease and other disorders. Neurology 63: 2001-2005.
    • (2004) Neurology , vol.63 , pp. 2001-2005
    • Pearce, D.A.1    Atkinson, M.2    Tagle, D.A.3
  • 17
    • 20444441569 scopus 로고    scopus 로고
    • Evidence for a link between sphingolipid metabolism and expression of CD1d and MHC-class II: Monocytes from Gaucher disease patients as a model
    • Balreira A, Lacerda L, Miranda CS, Arosa FA (2005) Evidence for a link between sphingolipid metabolism and expression of CD1d and MHC-class II: monocytes from Gaucher disease patients as a model. Br J Haematol 129: 667-676.
    • (2005) Br J Haematol , vol.129 , pp. 667-676
    • Balreira, A.1    Lacerda, L.2    Miranda, C.S.3    Arosa, F.A.4
  • 21
    • 37249025083 scopus 로고    scopus 로고
    • Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease
    • Galbiati F, Basso V, Cantuti L, Givogri MI, Lopez-Rosas A, et al. (2007) Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease. J Neurosci 27: 13730-13738.
    • (2007) J Neurosci , vol.27 , pp. 13730-13738
    • Galbiati, F.1    Basso, V.2    Cantuti, L.3    Givogri, M.I.4    Lopez-Rosas, A.5
  • 22
    • 33749346679 scopus 로고    scopus 로고
    • Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases
    • Gadola SD, Silk JD, Jeans A, Illarionov PA, Salio M, et al. (2006) Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases. J Exp Med 203: 2293-2303.
    • (2006) J Exp Med , vol.203 , pp. 2293-2303
    • Gadola, S.D.1    Silk, J.D.2    Jeans, A.3    Illarionov, P.A.4    Salio, M.5
  • 23
    • 0035260881 scopus 로고    scopus 로고
    • Chemokines and disease
    • Gerard C, Rollins BJ (2001) Chemokines and disease. Nat Immunol 2: 108-115.
    • (2001) Nat Immunol , vol.2 , pp. 108-115
    • Gerard, C.1    Rollins, B.J.2
  • 24
    • 0035908021 scopus 로고    scopus 로고
    • + dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC
    • + dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC. J Exp Med 193: 1393-1402.
    • (2001) J Exp Med , vol.193 , pp. 1393-1402
    • Ishikawa, S.1    Sato, T.2    Abe, M.3    Nagai, S.4    Onai, N.5
  • 25
    • 10944231564 scopus 로고    scopus 로고
    • Aberrant B1 cell migration into the thymus results in activation of CD4 T cells through its potent antigen-presenting activity in the development of murine lupus
    • Sato T, Ishikawa S, Akadegawa K, Ito T, Yurino H, et al. (2004) Aberrant B1 cell migration into the thymus results in activation of CD4 T cells through its potent antigen-presenting activity in the development of murine lupus. Eur J Immunol 34: 3346-3358.
    • (2004) Eur J Immunol , vol.34 , pp. 3346-3358
    • Sato, T.1    Ishikawa, S.2    Akadegawa, K.3    Ito, T.4    Yurino, H.5
  • 26
    • 34249826618 scopus 로고    scopus 로고
    • Aberrant B1 cell trafficking in a murine model for lupus
    • Ishikawa S, Matsushima K (2007) Aberrant B1 cell trafficking in a murine model for lupus. Front Biosci 12: 1790-1803.
    • (2007) Front Biosci , vol.12 , pp. 1790-1803
    • Ishikawa, S.1    Matsushima, K.2
  • 27
    • 0020681403 scopus 로고
    • The "Ly-1 B" cell subpopulations in normal, immunodefective, and autoimmune mice
    • Hayakawa K, Hardy RR, Parks DR, Herzenberg LA (1983) The "Ly-1 B" cell subpopulations in normal, immunodefective, and autoimmune mice. J Exp Med 157: 202-218.
    • (1983) J Exp Med , vol.157 , pp. 202-218
    • Hayakawa, K.1    Hardy, R.R.2    Parks, D.R.3    Herzenberg, L.A.4
  • 29
    • 0033919570 scopus 로고    scopus 로고
    • B-1 cells: The lineage question revisited
    • Herzenberg LA (2000) B-1 cells: the lineage question revisited. Immunol Rev 175: 9-22.
    • (2000) Immunol Rev , vol.175 , pp. 9-22
    • Herzenberg, L.A.1
  • 30
    • 2942563944 scopus 로고    scopus 로고
    • Deletion of macrophage-inflammatory protein 1α retards neurodegeneration in Sandhoff disease mice
    • Wu Y-P, Proia RL (2004) Deletion of macrophage-inflammatory protein 1α retards neurodegeneration in Sandhoff disease mice. Proc Natl Acad Sci U S A 101: 8425-8430.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8425-8430
    • Wu, Y.-P.1    Proia, R.L.2
  • 31
    • 33745939483 scopus 로고    scopus 로고
    • The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis
    • Meraouna A, Cizeron-Clairac G, Panse RL, Bismuth J, Truffault F, et al. (2006) The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis. Blood 108: 432-440.
    • (2006) Blood , vol.108 , pp. 432-440
    • Meraouna, A.1    Cizeron-Clairac, G.2    Panse, R.L.3    Bismuth, J.4    Truffault, F.5
  • 33
    • 13244272042 scopus 로고    scopus 로고
    • Pathogenesis of some neurological immune ultrastructural and morphometrical observations on rat thymus
    • Cavallotti D, D'Andrea V, Pastore FS, Leali FMT, Cavallotti C (2005) Pathogenesis of some neurological immune ultrastructural and morphometrical observations on rat thymus. Neurol Res 27: 41-46.
    • (2005) Neurol Res , vol.27 , pp. 41-46
    • Cavallotti, D.1    D'andrea, V.2    Pastore, F.S.3    Leali, F.M.T.4    Cavallotti, C.5
  • 34
    • 10044280324 scopus 로고    scopus 로고
    • Lysosomal glycosphingolipid recognition by NKT cells
    • Zhou D, Mattner J, Cantu C, Schrantz N, Yin N, Gao Y, et al. (2004) Lysosomal glycosphingolipid recognition by NKT cells. Science 306: 1786-1789.
    • (2004) Science , vol.306 , pp. 1786-1789
    • Zhou, D.1    Mattner, J.2    Cantu, C.3    Schrantz, N.4    Yin, N.5    Gao, Y.6
  • 35
  • 37
    • 0019490892 scopus 로고
    • Glycolipids of murine lymphocyte subpopulations: A defect in the levels of sialidase-sensitive sialosylated asialo GM1 in beige mouse lymphocytes
    • Schwarting GA, Gajewski A (1981) Glycolipids of murine lymphocyte subpopulations: a defect in the levels of sialidase-sensitive sialosylated asialo GM1 in beige mouse lymphocytes. J Immunol 126: 2403-2407.
    • (1981) J Immunol , vol.126 , pp. 2403-2407
    • Schwarting, G.A.1    Gajewski, A.2
  • 38
    • 0020581719 scopus 로고
    • Glycolipids of murine lymphocyte subpopulations. Structural characterization of thymus gangliosides
    • Schwarting GA, Gajewski A (1983) Glycolipids of murine lymphocyte subpopulations. Structural characterization of thymus gangliosides. J Biol Chem 258: 5893-5898.
    • (1983) J Biol Chem , vol.258 , pp. 5893-5898
    • Schwarting, G.A.1    Gajewski, A.2
  • 39
    • 15244355223 scopus 로고    scopus 로고
    • Specific induction of macrophage inflammatory protein 1-α in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates
    • Tsuji D, Kuroki A, Ishibashi Y, Itakura T, Kuwahara J, et al. (2005) Specific induction of macrophage inflammatory protein 1-α in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates. J Neurochem 92: 1497-1507.
    • (2005) J Neurochem , vol.92 , pp. 1497-1507
    • Tsuji, D.1    Kuroki, A.2    Ishibashi, Y.3    Itakura, T.4    Kuwahara, J.5
  • 40
    • 0037378110 scopus 로고    scopus 로고
    • Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis
    • Jeyakumar M, Thomas R, Elliot-Smith E, Smith DA, van der Spoel AC, et al. (2003) Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. Brain 126: 974-987.
    • (2003) Brain , vol.126 , pp. 974-987
    • Jeyakumar, M.1    Thomas, R.2    Elliot-Smith, E.3    Smith, D.A.4    van der Spoel, A.C.5
  • 41
    • 33750465224 scopus 로고    scopus 로고
    • Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
    • Kawane K, Ohtani M, Miwa K, Kizawa T, Kanbara Y, et al. (2004) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443: 998-1002.
    • (2004) Nature , vol.443 , pp. 998-1002
    • Kawane, K.1    Ohtani, M.2    Miwa, K.3    Kizawa, T.4    Kanbara, Y.5
  • 42
    • 47849085872 scopus 로고    scopus 로고
    • The NALP3 inflammasome is involved in the innate immune response to amyloid-β
    • Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, et al. (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-β. Nat Immunol 9: 857-865.
    • (2008) Nat Immunol , vol.9 , pp. 857-865
    • Halle, A.1    Hornung, V.2    Petzold, G.C.3    Stewart, C.R.4    Monks, B.G.5
  • 43
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856.
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5
  • 44
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Petrilli V, Van BR, Steele C, Mossman BT, et al. (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van, B.R.3    Steele, C.4    Mossman, B.T.5
  • 45
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, et al. (2008) The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452: 103-107.
    • (2008) Nature , vol.452 , pp. 103-107
    • Muruve, D.A.1    Petrilli, V.2    Zaiss, A.K.3    White, L.R.4    Clark, S.A.5
  • 46
    • 36849045915 scopus 로고    scopus 로고
    • The inflammasome: A danger sensing complex triggering innate immunity
    • Petrilli V, Dostert C, Muruve DA, Tschopp J (2007) The inflammasome: a danger sensing complex triggering innate immunity. Curr Opin Immunol 19: 615-622.
    • (2007) Curr Opin Immunol , vol.19 , pp. 615-622
    • Petrilli, V.1    Dostert, C.2    Muruve, D.A.3    Tschopp, J.4
  • 47
    • 0021752040 scopus 로고
    • The fine structure of cytoplasmic inclusions in brain and other visceral organs in Sandhoff disease
    • Itoh H, Tanaka J, Morihana Y, Tamaki T (1984) The fine structure of cytoplasmic inclusions in brain and other visceral organs in Sandhoff disease. Brain Dev 6: 467-474.
    • (1984) Brain Dev , vol.6 , pp. 467-474
    • Itoh, H.1    Tanaka, J.2    Morihana, Y.3    Tamaki, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.